EKS-DAR-00827

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-DAR-00827

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/ULK	391.4	4.3E-117	9	271	263

Status

Unreviewed

Ensembl Protein

ENSDARP00000113763

UniProt Accession

E9QIB7;

Protein Name

Protein Synonyms/Alias

Gene Name

ulk1b

Gene Synonyms/Alias

ulk1b;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSDARG00000074481	ENSDARP00000098248	ENSDART00000112407
ENSDARG00000074481	ENSDARP00000113763	ENSDART00000131237

Organism

Danio rerio

Functional Description

Protein Length

1011

Protein Sequence
(FASTA)

METVGKFEFS RKDLIGHGAF AVVFKGRHRE KHEWEVAVKC INKKNLAKSQ TLLGKEIKIL 60

KELKHENIVA LHDFQETASS VYLVMEYCNG GDLADYLHSK GTLSEDTIRV FLQQITGAMR 120

VLQAKGIIHR DLKPQNILLS HPAGRKSHFN NTCIKIADFG FARYLQNNMM AATLCGSPMY 180

MAPEVIMSQN YDAKADLWSI GTIVFQCLTG KAPFQASSPQ DLRLFYEKNK TLSPNIPRET 240

STHLRHLLLG LLQRNHKDRM DFDEFFRHPF LEASSSMKKS TPVTVTCFPN SASASSCSSS 300

STSHLASPPQ SLAEIQHVRA KALASPTQDS PGYLLKDSGG GGGGSSSKNS SCDTDDFVMV 360

PAHFPSELTC DMPTGKVLQD SLMYSGSSLL ASGGQCSQGK TPPRSPSFSS SPGPSGRPSE 420

FSGSSYGNYG QSVPIPVPTQ IHNYQRMEQN FQFPGQEGSP RSGLAQRCSS GSFLACGRTG 480

PSPPRSGSAV MSRRLSTGGS KPFQLSPQVG TIPELPGQVC PASAEVGHRG SRGGEAKTWP 540

QQQGLGTRLN SAPCLLEAAG GCRQKIRKQH SDPVVAPQAN VMPFRTLHSS PRLSELMQRN 600

PLPTILGSPS RAMPPFEFPK PPSSPNMVTF LTQQGLRTAQ GEPSYSPAYQ PEERKGFGRS 660

QSAGRLSDVL LMAAFGGQRG ERGSMENLNT DRAIDITAPP GGGGIVVGSG SPARVVFTIG 720

SPPSGATPPQ NSRSRKLSAG SSSSVSPVGS LTSRYTQAGN YMDCYEGSSS PRYGFSDPIS 780

AVTFEAPELP EETLMEQEHT ETLCRLRFML DFARCMVEVA GARSGEMAQT ELSSTSLLQQ 840

QSLMADQISS LSREWSYAEQ LVLYMKTAEL LSSSLQTAME GIKQGKLYPS STVKQVVRRL 900

NDLYKSSVMS CRSLSNQLER FFTRKHKLMD HINSITAERL LFGHTVQMVQ AAALDEMFHQ 960

GEASIQRYHK ALLLMEGLSL LLTEQADILS ISKCKQCIER RLTALQSGLC V 1011

Nucleotide Sequence
(FASTA)

ATGGAGACTG TCGGGAAATT CGAGTTCAGC AGGAAGGACC TCATAGGACA CGGTGCCTTC 60

GCAGTGGTTT TCAAAGGCAG ACATCGAGAG AAGCATGAAT GGGAGGTTGC CGTCAAATGC 120

ATAAACAAGA AGAATTTGGC CAAATCGCAG ACTCTTCTGG GCAAAGAAAT CAAGATATTG 180

AAGGAACTGA AACATGAAAA CATCGTTGCA TTGCACGACT TTCAGGAAAC GGCTAGCTCC 240

GTGTACCTTG TAATGGAGTA CTGCAACGGG GGAGACCTGG CTGACTACTT GCACTCAAAG 300

GGCACTTTAA GTGAAGACAC CATCCGAGTA TTCCTACAGC AGATCACAGG GGCCATGAGG 360

GTTCTGCAGG CCAAAGGGAT CATCCACAGA GACCTGAAAC CCCAAAACAT CCTGTTGTCC 420

CATCCTGCAG GCCGAAAGTC TCACTTCAAC AACACCTGCA TTAAGATAGC TGACTTTGGC 480

TTTGCGAGGT ACCTCCAGAA CAACATGATG GCTGCCACTC TCTGTGGGTC TCCGATGTAC 540

ATGGCTCCTG AAGTTATCAT GTCACAAAAC TATGATGCCA AGGCTGACCT GTGGAGCATA 600

GGGACCATTG TGTTTCAGTG TCTGACTGGG AAGGCTCCAT TTCAGGCCAG CAGTCCCCAG 660

GATCTCCGCT TGTTTTATGA GAAAAATAAA ACTCTTAGCC CAAACATTCC CAGAGAAACT 720

TCCACCCATC TCAGACACCT GCTGCTCGGC CTCCTGCAGA GGAACCATAA GGACCGAATG 780

GACTTCGATG AATTCTTCAG ACATCCATTT TTGGAAGCAA GCTCATCTAT GAAGAAGTCT 840

ACACCAGTGA CCGTGACATG CTTTCCCAAT TCAGCCTCTG CAAGCTCATG CAGCAGTTCA 900

TCTACTTCAC ACCTGGCCTC TCCTCCTCAA TCGCTTGCTG AGATCCAGCA TGTCCGTGCA 960

AAGGCGTTAG CCTCCCCTAC CCAGGATTCT CCAGGATATC TGCTGAAAGA CTCAGGAGGA 1020

GGTGGAGGAG GCAGCAGTAG CAAAAACTCA TCCTGTGACA CTGATGATTT CGTCATGGTT 1080

CCAGCTCATT TCCCCAGTGA GCTTACCTGT GACATGCCAA CTGGAAAGGT TCTCCAGGAC 1140

AGTTTGATGT ATAGCGGGAG TTCTCTTCTG GCGTCCGGAG GTCAGTGCAG TCAAGGAAAG 1200

ACTCCGCCAC GCTCTCCATC ATTCAGCAGC TCTCCAGGAC CCAGCGGCAG GCCGAGTGAG 1260

TTTTCTGGGA GTAGCTATGG CAACTATGGG CAGTCTGTAC CCATTCCAGT GCCCACACAG 1320

ATTCACAACT ACCAGCGCAT GGAGCAAAAC TTCCAGTTTC CAGGTCAAGA GGGTTCTCCT 1380

CGATCTGGTT TGGCTCAGAG ATGCAGTAGT GGTAGTTTTC TGGCCTGTGG AAGGACAGGG 1440

CCTTCTCCTC CTCGGTCTGG TTCTGCTGTC ATGTCCCGCA GGCTTTCCAC AGGAGGCAGC 1500

AAACCCTTCC AGCTCTCTCC ACAGGTGGGC ACCATTCCTG AATTGCCAGG CCAAGTTTGC 1560

CCAGCGAGTG CAGAAGTGGG TCACAGGGGC TCTCGTGGTG GAGAAGCCAA GACTTGGCCT 1620

CAGCAGCAGG GTCTAGGCAC GCGGCTCAAC AGTGCCCCCT GTTTGCTGGA GGCCGCTGGA 1680

GGCTGCAGGC AGAAGATCAG GAAGCAGCAC TCAGATCCAG TGGTCGCCCC TCAGGCAAAC 1740

GTGATGCCCT TCAGGACCCT GCACTCCTCA CCCAGGCTCA GTGAACTTAT GCAACGCAAC 1800

CCCCTACCAA CTATCCTGGG TTCTCCTTCA AGAGCCATGC CCCCGTTTGA GTTTCCCAAG 1860

CCTCCGAGTT CCCCAAACAT GGTCACATTT CTGACCCAGC AGGGCCTCAG AACAGCTCAG 1920

GGAGAGCCTA GTTATTCACC TGCCTACCAG CCAGAGGAGC GGAAAGGATT TGGGAGGTCT 1980

CAGAGCGCTG GTCGCCTGTC TGATGTGCTG CTGATGGCAG CATTTGGAGG ACAGAGAGGA 2040

GAACGAGGCA GCATGGAGAA TCTCAACACT GACAGAGCCA TCGACATCAC AGCGCCACCT 2100

GGTGGTGGGG GCATCGTGGT CGGCTCAGGT AGCCCTGCTC GAGTGGTGTT CACCATTGGT 2160

TCTCCACCCA GTGGAGCAAC ACCTCCGCAG AATTCTCGCT CAAGAAAGCT CTCCGCAGGT 2220

TCTTCAAGCT CCGTTAGTCC AGTAGGCTCT CTCACCAGCC GCTACACACA AGCAGGCAAT 2280

TACATGGACT GCTATGAGGG ATCTTCCAGT CCCCGCTACG GTTTCTCTGA CCCCATCTCA 2340

GCCGTGACTT TTGAAGCCCC TGAACTACCA GAGGAGACCC TGATGGAACA GGAACACACG 2400

GAGACTCTTT GCAGGCTCCG CTTCATGCTG GACTTTGCTC GTTGTATGGT GGAGGTAGCA 2460

GGAGCTCGGA GTGGAGAGAT GGCCCAGACT GAGCTCTCCT CCACCAGCCT GCTCCAACAA 2520

CAGAGCCTGA TGGCCGACCA GATCAGCTCT CTGAGCCGAG AGTGGAGTTA TGCTGAGCAG 2580

TTGGTGCTTT ACATGAAGAC CGCAGAGCTT CTGTCATCTT CACTACAAAC AGCCATGGAA 2640

GGAATCAAGC AGGGAAAATT GTACCCCTCA AGCACCGTCA AACAAGTGGT CAGGAGGTTG 2700

AATGACCTGT ACAAGTCCAG CGTGATGTCC TGTCGGTCTC TGAGCAATCA GCTGGAGCGA 2760

TTCTTCACCC GAAAACACAA ACTCATGGAC CACATCAACA GCATCACTGC AGAAAGGCTC 2820

CTCTTCGGCC ACACTGTGCA AATGGTGCAG GCTGCAGCTC TGGATGAGAT GTTTCATCAG 2880

GGGGAAGCAT CAATTCAGCG CTACCATAAG GCCTTGCTGC TCATGGAGGG TCTGTCGCTT 2940

CTCCTCACTG AACAGGCTGA CATCCTTAGC ATTAGCAAGT GTAAACAATG CATTGAACGC 3000

CGTCTCACCG CCTTGCAGTC GGGTCTCTGT GTGTAA 3036

Domain Profile

S: 1     ysleeeiGkGsfavvykgrlrkktsqvvAikvvekkklkkslenlekeikilkelkheni  60

         +s ++ iG+G+favv+kgr+r+k++++vA+k+++kk+l+ks++ l keikilkelkheni

Q: 9     FSRKDLIGHGAFAVVFKGRHREKHEWEVAVKCINKKNLAKSQTLLGKEIKILKELKHENI  68

         7889********************************************************

S: 61    valldveetskevylvmeycaggdLakllkqkkeLsedtvreflqqlasalkaLhskkiv  120

         val+d++et+++vylvmeyc+ggdLa++l++k++Lsedt+r+flqq+  a+++L++k+i+

Q: 69    VALHDFQETASSVYLVMEYCNGGDLADYLHSKGTLSEDTIRVFLQQITGAMRVLQAKGII  128

         ************************************************************

S: 121   hrDlkPqniLlsyadakk.elkkvtlkladFglarvlkeesmaatlkGsplYmaPEvvke  179

         hrDlkPqniLls+  ++k +++++++k+adFg+ar+l++++maatl+Gsp+YmaPEv+++

Q: 129   HRDLKPQNILLSHPAGRKsHFNNTCIKIADFGFARYLQNNMMAATLCGSPMYMAPEVIMS  188

         ************99998889****************************************

S: 180   qqydakaDlWSiGtilyellvGkpPfaaesiseLvekiekndvleppipkeisselkdll  239

         q+ydakaDlWSiGti++++l+Gk+Pf+a+s+++L+ ++ekn++l+p+ip+e+s++l++ll

Q: 189   QNYDAKADLWSIGTIVFQCLTGKAPFQASSPQDLRLFYEKNKTLSPNIPRETSTHLRHLL  248

         ************************************************************

S: 240   qsLLqrdpkkRisfeelfahpfl  262

          +LLqr++k+R++f+e+f+hpfl

Q: 249   LGLLQRNHKDRMDFDEFFRHPFL  271

         *********************96

Domain Sequence
(FASTA)

FSRKDLIGHG AFAVVFKGRH REKHEWEVAV KCINKKNLAK SQTLLGKEIK ILKELKHENI 60

VALHDFQETA SSVYLVMEYC NGGDLADYLH SKGTLSEDTI RVFLQQITGA MRVLQAKGII 120

HRDLKPQNIL LSHPAGRKSH FNNTCIKIAD FGFARYLQNN MMAATLCGSP MYMAPEVIMS 180

QNYDAKADLW SIGTIVFQCL TGKAPFQASS PQDLRLFYEK NKTLSPNIPR ETSTHLRHLL 240

LGLLQRNHKD RMDFDEFFRH PFL 263

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

dre:558848

;

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.
IPR022708	; Ser/Thr_kinase_C.

Pfam

PF12063	; DUF3543; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013