EKS-DAR-00775

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-DAR-00775

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE11	314.7	1.2E-93	1065	1329	265

Status

Unreviewed

Ensembl Protein

ENSDARP00000116651

UniProt Accession

E7FBI5;

Protein Name

Protein Synonyms/Alias

Gene Name

si:rp71-80a19.2

Gene Synonyms/Alias

si:rp71-80a19.2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSDARG00000088180	ENSDARP00000110235	ENSDART00000126052
ENSDARG00000088180	ENSDARP00000116651	ENSDART00000139062

Organism

Danio rerio

Functional Description

Protein Length

1334

Protein Sequence
(FASTA)

MENKETLRGL QKMEDRPEER LIREKLKATC MPTWKSEWLE RRSRRGPMVV KPIPLRADGT 60

EAGSDSHNSS SSQSRGQRSP SPGPSSFSAA SSSSSSSSTK TAGKPDSPGL RRRRASPVPS 120

GRVTPPRRAP SPDGFSPYSP EETSRRVNKV MRARLYLLQQ IGPNSFLIGG DSPDNKFRVF 180

IGPQTCSCGR GTFCIHVLFV MLRVFQLEPS DPLLWRKTLK NFEVESLFQK YHNRRSSRIK 240

APSRSTIQKF VSRMSNSHTS CTSSASPSSN ESSMKDEEEQ MCPICLLDML DEESLTVCEE 300

GCRNKLHHHC MSIWAEECRR NHDPLICPLC RAKWKPHDFY SYEAPSTVES TTSRSQSQTA 360

ASSSSSSSSL HAESSRTGQD GDFSLPQYGV QHIPQTYTEL AEPWIKVFGL ELVGCLFSRN 420

WNIREMALRR LSHDVSGALL LANGEHSLAG AGAGAGLAEV SGDVVVESCC SVLSMVCADP 480

VYKVYVAALK TLRAMLVYTP CHSASERTRL QQLLRPVVET ILVKCADANS RTSQLSVSTL 540

LELCKGQMGE LAVGREILKA GSIGIGGVDY VLNCILGSKT EANNWQALLG RLCLIDRLLL 600

EFPAEFYPHI VSGGDCNQAQ NVVERYQKLL PLLSFALKSI DNSHSMVGKL SRRVFLSAAR 660

MVARVPHVFV KLLDMLNVTS STHYARMRRR LLAIAEEMDI LDAIHLGLDD LQKEHTSPSC 720

AFLEPSAPHN SPCTTERSSP THGLQQPAAK VALSGQASST PVEDITERLS NIVASPAEFP 780

KPPIQARNRP VSQCLNSPSS GQPPSLPSLS MANASAFPPE NPKALPQSFI PSKFAQSSLG 840

SQRKLPLQKG ACSSKEPEKL PSPVFTQARP LPQSQIHRPR PSRPTPAASS DGAKALSPLT 900

KGNMKLDLQE ARSRDDVACS GGSALIPSED TAFTPVEEKF HGLDASADLS SSMEDLLEAS 960

IPAADSTVTF QSEVAVLSPE QANANDDTYS EDVTQNQKCK EKMEAEEEEA LAVVMAMSES 1020

QDALPVIPQL QVDKGEDVII IQVDTPETLP GHTKAKQPYR EGNEWLKGQQ IGLGAFSSCY 1080

QAQDVGTGTL MAVKQVTYVR NTSSEQEEVV EALREEIRMM GLLNHPHIIR MLGATCEKNN 1140

YNLFVEWMAG GSVSHLLNKY GAFKEGVIIN YTEQLLRGLA YLHENQIIHR DIKGANLLID 1200

STGQRLRIAD FGAAARLASK GTGAGEFQGQ LLGTIAFMAP EVLRGQQYGR SCDVWSVGCA 1260

IIEMSCAKPP WNAEKHSNHL ALIFKIASAT TAPSIPPHLS PGLRDVTLRC LELQPTDRPP 1320

SRELLKHPVF RHSW 1334

Nucleotide Sequence
(FASTA)

ATGGAGAACA AGGAGACTCT GCGCGGGCTG CAGAAGATGG AGGACCGGCC TGAGGAGCGA 60

CTGATCCGAG AGAAGCTCAA GGCCACCTGT ATGCCCACCT GGAAGAGCGA GTGGCTGGAG 120

AGGCGGAGCA GGAGAGGACC AATGGTTGTG AAGCCCATTC CTCTGAGAGC CGACGGCACT 180

GAAGCCGGGA GTGACAGTCA CAACTCTTCT TCATCCCAGA GCCGAGGTCA ACGCAGCCCG 240

TCTCCCGGAC CTTCCTCTTT CTCAGCCGCT TCCTCCTCCT CATCATCGTC CTCCACAAAG 300

ACTGCTGGGA AGCCAGATTC TCCTGGCCTA CGCAGACGGA GAGCTTCACC AGTGCCCAGT 360

GGACGTGTGA CCCCTCCTCG AAGAGCTCCC TCCCCTGATG GCTTTTCCCC ATACAGTCCA 420

GAGGAGACCA GCCGCAGGGT CAACAAGGTC ATGAGGGCGC GCCTGTACCT GCTCCAGCAA 480

ATAGGACCCA ACTCATTCTT GATTGGCGGA GACAGTCCTG ACAACAAGTT CAGGGTGTTC 540

ATTGGTCCAC AGACCTGCAG CTGCGGCAGA GGAACTTTCT GCATCCATGT GCTCTTCGTC 600

ATGCTCCGAG TTTTCCAGCT GGAGCCTTCA GATCCTCTTC TGTGGCGGAA AACCCTCAAG 660

AATTTTGAGG TGGAGAGCTT ATTTCAGAAG TACCACAATC GCCGCAGCTC CCGCATCAAA 720

GCTCCCTCAC GCAGCACCAT CCAGAAGTTT GTGTCCCGCA TGTCCAACTC TCACACCTCG 780

TGTACCTCCA GTGCCTCACC ATCCAGTAAT GAAAGCAGTA TGAAGGACGA GGAGGAGCAG 840

ATGTGTCCCA TCTGTCTGCT GGACATGCTG GATGAAGAAA GTCTGACAGT GTGTGAAGAG 900

GGCTGCCGAA ACAAACTCCA CCATCACTGC ATGTCTATAT GGGCCGAGGA GTGCAGAAGA 960

AATCACGATC CTTTAATCTG CCCACTGTGT AGAGCCAAAT GGAAGCCTCA TGATTTTTAC 1020

AGTTATGAAG CGCCATCTAC TGTGGAAAGC ACAACCAGCC GCTCTCAGAG TCAAACAGCT 1080

GCTTCATCAT CATCATCATC TTCATCTCTT CATGCTGAGA GCTCCAGGAC GGGCCAGGAT 1140

GGAGACTTCT CTCTTCCTCA ATATGGAGTT CAGCACATCC CTCAGACGTA CACGGAGCTC 1200

GCCGAACCCT GGATCAAGGT GTTTGGATTG GAGCTGGTCG GCTGCCTCTT CTCTCGTAAC 1260

TGGAACATCA GAGAAATGGC TCTGCGGCGG CTGTCCCATG ACGTGAGTGG AGCCCTGCTC 1320

TTGGCCAACG GCGAGCACTC ATTGGCCGGA GCGGGTGCAG GGGCAGGGCT GGCCGAGGTA 1380

TCTGGAGACG TGGTGGTGGA GTCCTGCTGT AGTGTGCTCT CCATGGTCTG TGCAGACCCT 1440

GTCTACAAAG TCTACGTAGC AGCGCTGAAA ACCCTGCGAG CGATGCTTGT CTACACCCCA 1500

TGCCACTCTG CTTCAGAGAG GACTCGATTA CAGCAGCTTC TGCGGCCCGT GGTGGAAACC 1560

ATACTGGTCA AGTGTGCAGA TGCTAACAGT CGCACCAGTC AGCTGTCCGT GTCCACTCTG 1620

CTGGAGCTGT GCAAAGGTCA AATGGGAGAA CTCGCTGTGG GCAGAGAAAT TCTCAAAGCA 1680

GGCTCTATTG GTATTGGTGG AGTTGACTAT GTCCTGAACT GCATCTTGGG CTCTAAAACG 1740

GAGGCCAATA ACTGGCAAGC ACTGCTGGGT CGGCTGTGTC TGATTGACAG GCTCTTACTG 1800

GAGTTTCCTG CTGAATTCTA CCCTCACATC GTGTCAGGTG GAGACTGCAA CCAGGCGCAA 1860

AACGTTGTGG AGAGGTACCA GAAGCTGCTG CCTCTTCTAA GTTTTGCTCT GAAGTCCATT 1920

GATAACTCTC ACTCCATGGT GGGAAAGCTT TCTCGTCGTG TCTTCCTGAG CGCTGCCCGT 1980

ATGGTAGCTC GTGTGCCTCA TGTCTTCGTT AAGCTACTGG ACATGCTCAA CGTCACCAGC 2040

TCCACCCACT ATGCACGCAT GCGCCGGCGT CTTCTGGCCA TTGCGGAGGA GATGGACATC 2100

CTGGATGCGA TTCATCTGGG ACTAGATGAC CTACAGAAAG AGCACACCTC ACCCTCTTGT 2160

GCTTTCCTTG AACCCTCAGC CCCTCATAAC TCCCCATGTA CGACTGAAAG AAGCTCCCCC 2220

ACCCATGGTC TACAGCAGCC CGCCGCTAAG GTGGCACTTT CAGGTCAAGC CAGTTCTACT 2280

CCTGTAGAGG ACATAACCGA GAGACTCTCA AACATAGTCG CTAGCCCTGC TGAATTTCCA 2340

AAGCCCCCCA TTCAGGCTCG AAACAGACCC GTTAGTCAGT GTCTGAACTC CCCCTCATCT 2400

GGTCAACCCC CAAGCCTTCC TTCTCTGTCC ATGGCCAATG CCTCAGCCTT CCCTCCAGAA 2460

AACCCCAAAG CCCTGCCACA GAGTTTTATT CCCAGCAAGT TTGCCCAGTC CTCACTGGGT 2520

TCCCAACGCA AGTTGCCTCT TCAGAAAGGT GCCTGTAGTA GTAAAGAACC AGAGAAGCTT 2580

CCATCCCCTG TGTTTACTCA AGCTCGGCCA CTGCCCCAGA GTCAGATCCA CCGGCCCAGA 2640

CCTTCTCGAC CCACTCCTGC TGCCTCATCT GATGGAGCTA AAGCTTTAAG CCCTTTGACA 2700

AAGGGCAACA TGAAACTGGA CCTTCAGGAG GCCCGGTCCA GAGATGATGT GGCCTGCAGT 2760

GGGGGATCTG CTCTCATCCC CAGTGAGGAC ACTGCCTTCA CGCCAGTGGA GGAGAAGTTC 2820

CACGGTCTGG ATGCTTCAGC CGATCTCAGC TCCAGCATGG AGGACCTGCT GGAAGCCTCT 2880

ATCCCTGCGG CAGACAGCAC GGTCACCTTC CAGTCTGAAG TGGCAGTGCT GTCCCCCGAG 2940

CAGGCAAATG CAAACGATGA CACGTACAGT GAAGACGTGA CCCAGAACCA GAAGTGCAAG 3000

GAGAAGATGG AAGCTGAAGA AGAGGAGGCA TTGGCTGTAG TCATGGCCAT GTCTGAGTCA 3060

CAAGACGCCC TACCTGTAAT CCCACAGTTA CAGGTGGACA AAGGGGAGGA CGTGATCATT 3120

ATTCAGGTGG ATACACCAGA GACTCTGCCT GGTCATACCA AAGCAAAGCA GCCATACAGG 3180

GAGGGAAACG AATGGCTAAA AGGTCAACAG ATTGGCCTGG GTGCCTTTTC GTCATGTTAC 3240

CAGGCTCAGG ATGTGGGCAC TGGGACTCTG ATGGCTGTCA AACAGGTGAC GTACGTGAGG 3300

AACACTTCAT CAGAGCAGGA GGAGGTGGTT GAGGCGCTAC GAGAGGAGAT TCGCATGATG 3360

GGTCTACTAA ACCACCCACA CATCATCCGC ATGCTGGGGG CAACCTGTGA GAAGAACAAC 3420

TACAACCTTT TCGTAGAGTG GATGGCAGGT GGCTCTGTAT CTCATCTCTT GAATAAGTAT 3480

GGCGCATTTA AAGAAGGTGT GATCATCAAC TACACGGAGC AGCTTCTGCG GGGTCTGGCC 3540

TACCTTCATG AGAACCAGAT CATCCACCGC GACATCAAAG GTGCCAATCT ACTGATTGAC 3600

AGCACAGGCC AGAGGCTGAG GATAGCTGAT TTTGGGGCTG CAGCACGTTT GGCTTCGAAA 3660

GGCACTGGAG CAGGGGAGTT CCAGGGTCAA CTTCTGGGAA CCATTGCCTT CATGGCTCCG 3720

GAGGTGCTGA GAGGACAGCA GTACGGCCGG AGCTGTGATG TCTGGAGTGT TGGCTGTGCC 3780

ATCATTGAGA TGTCCTGTGC TAAACCTCCC TGGAACGCTG AAAAACACTC CAACCACCTG 3840

GCGCTCATTT TCAAGATCGC CAGCGCCACC ACAGCGCCCT CCATCCCACC ACACTTGTCT 3900

CCAGGCCTGC GGGACGTGAC CCTGCGCTGT CTGGAGCTCC AGCCCACCGA CCGGCCGCCC 3960

TCCAGAGAGC TCCTGAAACA CCCCGTCTTC AGACACAGCT GGTAG 4005

Domain Profile

S: 1     wqkrevigkGsfgsvyaaldvdtgellavKeveikpekksekk.evkalkeEikllkelk  59

         w k+++ig G+f+s+y+a+dv tg+l+avK+v++ ++++se++ +v+al+eEi+++  l+

Q: 1065  WLKGQQIGLGAFSSCYQAQDVGTGTLMAVKQVTYVRNTSSEQEeVVEALREEIRMMGLLN  1124

         899*******************************999998887699**************

S: 60    HenivkyyGveveeeelkiflEyvegGslssllekygkleesvikkytkqileglayLHe  119

         H+ i++++G+++e++++++f+E+++gGs+s+ll+kyg+++e vi +yt+q+l+glayLHe

Q: 1125  HPHIIRMLGATCEKNNYNLFVEWMAGGSVSHLLNKYGAFKEGVIINYTEQLLRGLAYLHE  1184

         ************************************************************

S: 120   kkivHRDiKgaNillds.sgvvklsDFGaskrlaelntkaae.lesltGtlaymaPEvik  177

         ++i+HRDiKgaN+l+ds  + ++++DFGa++rla++ t a+e + +l Gt+a+maPEv++

Q: 1185  NQIIHRDIKGANLLIDStGQRLRIADFGAAARLASKGTGAGEfQGQLLGTIAFMAPEVLR  1244

         *****************7789******************9996779*************9

S: 178   kkekgygrkaDiWslgcvviemltgkrPfa..eldeelaimfkvgakktkPeipeklsee  235

         ++  +ygr++D+Ws+gc++iem ++k+P++  +++++la++fk+++++t+P+ip +ls+

Q: 1245  GQ--QYGRSCDVWSVGCAIIEMSCAKPPWNaeKHSNHLALIFKIASATTAPSIPPHLSPG  1302

         98..8************************87678899***********************

S: 236   gkdflekcleldpkkrpsaeeLLkhef  262

          +d+  +clel+p++rp ++eLLkh++

Q: 1303  LRDVTLRCLELQPTDRPPSRELLKHPV  1329

         *************************86

Domain Sequence
(FASTA)

WLKGQQIGLG AFSSCYQAQD VGTGTLMAVK QVTYVRNTSS EQEEVVEALR EEIRMMGLLN 60

HPHIIRMLGA TCEKNNYNLF VEWMAGGSVS HLLNKYGAFK EGVIINYTEQ LLRGLAYLHE 120

NQIIHRDIKG ANLLIDSTGQ RLRIADFGAA ARLASKGTGA GEFQGQLLGT IAFMAPEVLR 180

GQQYGRSCDV WSVGCAIIEM SCAKPPWNAE KHSNHLALIF KIASATTAPS IPPHLSPGLR 240

DVTLRCLELQ PTDRPPSREL LKHPV 265

Keyword

ATP-binding; Complete proteome; Metal-binding; Nucleotide-binding; Reference proteome; Zinc; Zinc-finger.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Vicugna pacos"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0008270	; F:zinc ion binding

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.
IPR001841	; Znf_RING.
IPR013083	; Znf_RING/FYVE/PHD.
IPR007527	; Znf_SWIM.

Pfam

PF00069	; Pkinase; 1.
PF04434	; SWIM; 1.

SMARTs

SM00184	; RING; 1.
SM00220	; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.
PS50089	; ZF_RING_2; 1.
PS50966	; ZF_SWIM; 1.

Prints

Created Date

20-Feb-2013