EKS-DAR-00580

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-DAR-00580

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMKL	286.2	4.0E-85	49	307	259

Status

Unreviewed

Ensembl Protein

ENSDARP00000118480

UniProt Accession

E7FDP6;

Protein Name

Protein Synonyms/Alias

Gene Name

hunk

Gene Synonyms/Alias

hunk; si:dkey-189i22.2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSDARG00000091317	ENSDARP00000118480	ENSDART00000142655
ENSDARG00000091317	ENSDARP00000106262	ENSDART00000128049

Organism

Danio rerio

Functional Description

Protein Length

609

Protein Sequence
(FASTA)

MIDAETDTGI DGGRMITEDK EVLKRGDVLK LLPPDADKNF YFKKKVSDYL IGRKLGEGSF 60

AIVREGLHVI TGEKVAVKII DKKKAKKDSY VLKNLRREGN IQQMIRHPHI AQLLDIMETE 120

NRFYLVMELC PGGNLMNYIY ENKRLEEREA NKYVRQLVMA VEHLHRAGVV HRDLKIENLL 180

LDDHDNLKLI DFGLSNSAGI LGYSDPFSTQ CGSPAYAAPE LLSRKKYGPK VDVWSIGVNM 240

YAMLTGTLPF TVEPFSLNAL YKKMINKEMN PLPSNISSDA KHLLEVLLEP KPDLRPNIHQ 300

VLSHPWLQLG NPHTGAPLFN RIHITEINKS VLCHMTEKMG YSHSAVLNAL LTNKASTTLA 360

VYFLLNNKMN RLSKECKQDK QRQNLDNREN KPEIIRLLKA VKGGFKDAYS GNGGCITSSS 420

LEYLKIHRLH PTPEPILPTP ETQPPEQCSS KDPPKAEKIP ARPPSSLGSH SWTSESKEPS 480

KDSPPSPWYK LTNGALSPPK HVSAFQPESS YLKKATIPSP PVLVVRPQPR KNAPSSDSMS 540

SSDSNGSPLS SRGSEEPQSP PIRGNKLTPK DFKQILRARF PLRIQNFPFK PESGLRRKSF 600

FPSDFKTRS 609

Nucleotide Sequence
(FASTA)

ATGATAGACG CTGAAACGGA CACGGGGATC GACGGCGGGA GGATGATTAC TGAAGATAAA 60

GAAGTCTTGA AACGTGGTGA TGTGCTCAAA CTTCTTCCAC CTGACGCTGA CAAAAACTTT 120

TACTTCAAAA AGAAAGTTTC CGACTATCTG ATCGGGAGGA AGCTGGGAGA AGGGTCTTTC 180

GCCATAGTGC GAGAGGGGCT TCATGTCATC ACCGGCGAGA AGGTGGCGGT GAAAATAATT 240

GACAAGAAGA AGGCTAAAAA GGATTCATAC GTCTTAAAGA ACCTGCGGCG TGAAGGAAAT 300

ATTCAGCAGA TGATCCGGCA CCCGCACATC GCCCAACTGC TGGACATAAT GGAGACGGAA 360

AACAGGTTCT ACCTCGTCAT GGAGCTCTGT CCTGGAGGAA ACCTCATGAA CTACATTTAC 420

GAGAACAAAA GATTGGAAGA AAGAGAAGCC AACAAATATG TCCGCCAGCT AGTGATGGCC 480

GTGGAACACC TGCACAGAGC AGGAGTTGTT CACAGAGACT TGAAGATTGA AAATCTCCTT 540

CTTGATGACC ATGACAACCT AAAGCTGATC GATTTTGGCC TAAGTAACTC GGCGGGAATT 600

CTGGGATACT CGGATCCCTT CAGCACACAG TGTGGCAGTC CAGCATATGC CGCCCCTGAG 660

CTTCTCTCAA GAAAGAAATA CGGCCCCAAA GTTGATGTTT GGTCAATAGG GGTGAACATG 720

TACGCTATGC TGACTGGTAC GCTGCCATTT ACAGTGGAGC CATTTAGCCT GAACGCTTTG 780

TATAAGAAGA TGATAAACAA GGAAATGAAC CCCCTTCCTT CGAATATCAG CTCAGATGCT 840

AAACATTTGC TGGAAGTGCT TCTAGAGCCT AAACCTGATT TGAGACCTAA CATCCATCAA 900

GTGTTATCTC ACCCGTGGCT TCAGTTGGGA AACCCTCACA CTGGAGCTCC TTTATTTAAT 960

AGGATCCACA TTACGGAAAT CAACAAGTCT GTTTTGTGCC ACATGACTGA GAAAATGGGC 1020

TACTCACACA GCGCTGTACT GAATGCATTG CTCACCAACA AAGCTTCCAC CACGCTAGCT 1080

GTGTACTTCC TCCTCAACAA CAAGATGAAC AGACTCTCAA AAGAGTGCAA GCAGGACAAA 1140

CAGCGGCAAA ACTTGGATAA TAGAGAGAAT AAGCCTGAGA TCATTCGTCT GCTGAAAGCC 1200

GTGAAAGGAG GATTTAAAGA TGCTTACTCA GGAAATGGCG GTTGTATCAC CTCGTCCTCC 1260

TTAGAGTACC TGAAGATTCA CCGCCTACAC CCAACCCCAG AGCCAATCCT TCCTACTCCC 1320

GAGACTCAAC CACCCGAACA ATGCAGCTCC AAAGATCCCC CAAAAGCTGA GAAAATTCCT 1380

GCTCGTCCAC CTTCTTCCCT CGGCTCTCAT TCCTGGACAT CCGAGAGCAA GGAACCGAGC 1440

AAAGACTCTC CTCCATCACC ATGGTACAAG CTGACCAATG GAGCGCTCTC TCCACCAAAA 1500

CACGTCTCTG CTTTCCAGCC TGAGAGCTCC TACTTGAAAA AGGCTACAAT CCCTAGCCCG 1560

CCTGTTCTCG TTGTCAGACC TCAGCCCAGG AAAAATGCTC CCAGTTCAGA CTCTATGAGC 1620

TCCTCAGACT CAAATGGAAG CCCGCTCAGC AGCAGGGGAA GCGAAGAACC ACAGAGTCCT 1680

CCAATCAGAG GCAATAAGCT CACTCCAAAG GACTTTAAGC AGATTTTGAG GGCAAGGTTT 1740

CCTTTGCGGA TACAGAACTT CCCATTCAAA CCGGAGTCTG GGTTGAGAAG GAAGAGCTTC 1800

TTCCCGAGCG ATTTTAAAAC CCGGAGTTGA 1830

Domain Profile

S: 1     ykllktlGegsfgkVklakhketkekvavKiikkkkl..seeslekikrEieilkklkhp  58

         y ++++lGegsf+ V++  h  t+ekvavKii+kkk+  ++  l++++rE +i+++++hp

Q: 49    YLIGRKLGEGSFAIVREGLHVITGEKVAVKIIDKKKAkkDSYVLKNLRREGNIQQMIRHP  108

         77899*****************************99844556689***************

S: 59    niikllevietkkklylvleyasggeLfdyieekgrlkekearklfkqlvsavkYlhskg  118

         +i +ll+++et++++ylv+e++ gg+L++yi e++rl+e+ea+k+++qlv av++lh+ g

Q: 109   HIAQLLDIMETENRFYLVMELCPGGNLMNYIYENKRLEEREANKYVRQLVMAVEHLHRAG  168

         ************************************************************

S: 119   ivHrDlKpeNllldkkenikiaDFGlan...lfkegklletfcGsppYaaPellkgkkYe  175

         +vHrDlK eNllld+++n+k++DFGl+n   ++ +++ ++t+cGsp+YaaPell++kkY

Q: 169   VVHRDLKIENLLLDDHDNLKLIDFGLSNsagILGYSDPFSTQCGSPAYAAPELLSRKKY-  227

         ****************************77677888***********************.

S: 176   gpkvDvWslGvvLyalvtgklPfdee..nlkellekilkgkl.eipkklskelesLlrkl  232

         gpkvDvWs+Gv +ya++tg+lPf+ e  +l++l++k+ ++++  +p+++s+++++Ll+ l

Q: 228   GPKVDVWSIGVNMYAMLTGTLPFTVEpfSLNALYKKMINKEMnPLPSNISSDAKHLLEVL  287

         ************************9988999****9999999789***************

S: 233   LvvdpekRatieeilkhewl  252

         L+ +p+ R++i+++l+h+wl

Q: 288   LEPKPDLRPNIHQVLSHPWL  307

         *******************7

Domain Sequence
(FASTA)

YLIGRKLGEG SFAIVREGLH VITGEKVAVK IIDKKKAKKD SYVLKNLRRE GNIQQMIRHP 60

HIAQLLDIME TENRFYLVME LCPGGNLMNY IYENKRLEER EANKYVRQLV MAVEHLHRAG 120

VVHRDLKIEN LLLDDHDNLK LIDFGLSNSA GILGYSDPFS TQCGSPAYAA PELLSRKKYG 180

PKVDVWSIGV NMYAMLTGTL PFTVEPFSLN ALYKKMINKE MNPLPSNISS DAKHLLEVLL 240

EPKPDLRPNI HQVLSHPWL 259

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013