EKS-DIO-00060

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-DIO-00060

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/MLK	270.7	9.3E-81	128	349	222

Status

Unreviewed

Ensembl Protein

ENSDORP00000001297

Gene Name

Map3k12

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSDORG00000001389	ENSDORP00000001297	ENSDORT00000001389

Organism

Dipodomys ordii

Protein Length

838

Protein Sequence
(FASTA)

MACLHETRTP SPSFGGFVST LSEASMRKLD PDTSDCTPEK DLTPTHVLQL HEQDSGGPGG 60

ATGSPESRAS RVRADEVRLQ CQSGSGFLEG LFGCLRPVWT MIGKAYSTEH KQQQEDLWEV 120

PFEEILDLQW VGSGAQGAVF LGRFHGEEVA VKKVRDLKET DIKHLRKLKH PNIITFKGVC 180

TQAPCYCILM EFCAQGQLYE VLRAGRPVTP SLLVDWSMGI AGGMNYLHLH KIIHRDLKSP 240

FGTSKELSDK STKMSFAGTV AWMAPEVIRN EPVSEKVDIW SFGVVLWELL TGEIPYKDVD 300

SSAIIWGVGS NSLHLPVPSS CPDGFKILLR QCWNSKPRNR PSFRQILLHL DIASADVLST 360

PQETYFKSQA EWREEVKLHF EKIKSEGTCL HRLEEELVMR RREELRHALD IREHYERKLE 420

RANNLYMELN ALMLQLELKE RELLRREQAL ERRCPGLLKS HPSRSLLHGN TMEKLIKKRN 480

VPQKLSPHSK RPDILKTESL LPKLDAALSG VGLPGCPKGP PSPGRSRRGK TRHRKASAKG 540

SCGDLPGLRA SVPPHEQGGL GMGPSVWEAC PPALRGLHHD LLLRKMSSSS PDLLSAALGA 600

RGRGATGGAG DPGSPPPARG DTPPSEGSAP GSTSPDSPGG AKGEPPPPGP GEGVGLLGTG 660

REGTTGRGSR AGAQHLTPAA LLYRAAVTRS QKRGISSEEE EGEVDSEVEL TSTQRWPQGL 720

NMRQSLSTFS SENPSDGEEG TASEPSPSGT PEVGSTNTDE RPDERSDDMC SQGSEIPLDP 780

PAAEVLPDPE PSSLPLSHQE LLTSKQGPPN SEDSDCDSTE LDNSNSIDAL RPPASLPP 838

Nucleotide Sequence
(FASTA)

ATGGCCTGCC TCCATGAGAC CAGGACACCC TCACCTTCCT TTGGGGGCTT TGTGTCTACC 60

CTAAGTGAGG CGTCCATGCG CAAGCTGGAC CCAGATACTT CGGACTGCAC CCCTGAGAAG 120

GACTTGACAC CTACCCATGT CCTGCAGCTG CATGAGCAGG ACTCAGGTGG CCCAGGGGGA 180

GCCACTGGGT CACCTGAAAG CCGAGCATCT AGAGTTCGAG CTGATGAGGT GCGACTGCAG 240

TGCCAGAGTG GCAGTGGCTT CCTTGAAGGT CTCTTTGGCT GCCTGCGCCC CGTTTGGACC 300

ATGATTGGCA AAGCCTACTC CACAGAGCAC AAGCAGCAGC AGGAAGACCT TTGGGAAGTA 360

CCCTTTGAGG AAATCTTGGA CCTGCAGTGG GTAGGCTCAG GGGCCCAGGG TGCTGTCTTT 420

CTGGGGCGCT TCCATGGGGA AGAGGTGGCT GTGAAGAAGG TACGCGACCT CAAGGAGACT 480

GACATCAAGC ACCTACGCAA ACTGAAGCAC CCCAACATTA TCACTTTCAA GGGTGTTTGT 540

ACACAGGCTC CCTGCTACTG CATCCTCATG GAGTTCTGCG CCCAGGGCCA GTTATATGAG 600

GTGCTTCGAG CTGGTCGCCC TGTTACCCCC TCCCTGCTAG TTGACTGGTC CATGGGCATT 660

GCTGGTGGCA TGAACTACCT GCATCTGCAC AAGATTATTC ACCGAGACCT CAAGTCCCCC 720

TTTGGCACTT CCAAGGAGCT GAGTGACAAG AGCACCAAGA TGTCCTTTGC AGGGACAGTA 780

GCTTGGATGG CCCCAGAGGT GATCCGCAAC GAGCCTGTGT CTGAGAAGGT TGACATCTGG 840

TCCTTTGGTG TGGTGCTATG GGAACTACTA ACTGGTGAAA TTCCCTATAA AGACGTAGAT 900

TCCTCAGCCA TCATCTGGGG TGTGGGAAGC AACAGTCTTC ACTTGCCTGT GCCCTCCAGC 960

TGCCCAGATG GCTTCAAAAT CCTGCTTCGC CAGTGCTGGA ATAGCAAACC ACGAAATCGT 1020

CCATCATTCC GACAGATCTT GCTACATCTA GATATTGCCT CAGCTGATGT GCTCTCCACA 1080

CCCCAAGAAA CTTACTTTAA GTCCCAGGCA GAGTGGCGGG AAGAGGTAAA GCTGCACTTT 1140

GAAAAGATTA AATCAGAAGG AACCTGTTTA CACCGCCTCG AAGAAGAGCT GGTGATGAGG 1200

AGGAGGGAAG AGCTCAGACA TGCCTTGGAC ATCAGGGAGC ACTATGAACG GAAGCTGGAG 1260

AGAGCCAACA ACTTATACAT GGAACTGAAT GCCCTCATGC TGCAGCTAGA ACTCAAGGAG 1320

CGTGAATTGC TAAGGCGGGA GCAAGCTTTA GAGCGCAGGT GCCCAGGACT ACTGAAGTCA 1380

CATCCATCAC GGAGTCTCTT GCATGGGAAC ACGATGGAGA AGCTCATCAA GAAGAGGAAT 1440

GTGCCACAGA AGCTGTCGCC CCATAGCAAA AGGCCAGATA TCCTCAAGAC AGAATCTTTG 1500

CTACCTAAAC TAGATGCAGC CCTAAGTGGG GTGGGGCTTC CTGGGTGTCC TAAGGGCCCC 1560

CCCTCACCAG GACGGAGCCG CCGTGGCAAG ACCCGTCACC GCAAGGCTAG CGCCAAAGGC 1620

AGCTGTGGGG ACCTGCCTGG CCTTCGTGCA TCTGTGCCAC CTCATGAACA AGGAGGCCTA 1680

GGAATGGGAC CCTCAGTCTG GGAGGCATGC CCCCCTGCCC TACGTGGGCT CCACCATGAC 1740

CTTCTGCTCC GCAAGATGTC ATCTTCCTCC CCAGATCTGC TGTCAGCAGC ATTAGGAGCC 1800

CGGGGCCGGG GGGCCACAGG GGGAGCTGGG GATCCTGGCT CACCACCTCC AGCCCGAGGT 1860

GATACTCCCC CAAGTGAGGG CTCAGCTCCT GGTTCCACCA GCCCAGATTC ACCTGGGGGA 1920

GCCAAAGGAG AGCCACCTCC ACCAGGACCT GGTGAAGGTG TGGGGCTGCT GGGAACTGGA 1980

AGGGAAGGGA CAACGGGTCG GGGAAGCCGG GCTGGAGCCC AGCACTTGAC ACCAGCTGCA 2040

CTGCTGTACA GGGCTGCGGT CACTCGAAGT CAGAAACGTG GCATATCATC AGAAGAGGAA 2100

GAAGGAGAGG TAGACAGTGA AGTAGAGCTG ACCTCAACCC AGAGGTGGCC TCAGGGCCTG 2160

AACATGCGCC AGTCACTGTC TACCTTCAGC TCAGAGAACC CATCAGATGG AGAGGAAGGC 2220

ACAGCTAGCG AACCTTCTCC TAGTGGCACA CCAGAAGTTG GTAGCACCAA CACTGATGAG 2280

CGACCAGACG AACGGTCTGA TGACATGTGC TCCCAGGGCT CAGAAATCCC ACTGGACCCA 2340

CCTGCTGCCG AGGTGCTCCC TGATCCTGAA CCCAGCTCCT TGCCTCTCTC ACACCAAGAA 2400

CTACTCACAA GCAAGCAGGG CCCTCCTAAT TCTGAGGACT CAGACTGTGA CAGCACTGAA 2460

TTGGACAACT CCAACAGCAT TGATGCCTTG CGGCCCCCAG CTTCCCTCCC TCCATGA 2517

Domain Profile

S: 4     eeligsgafgkvykakwrkkevavKklreeaeekekleklereakllsklshpniiellG  63

          +++gsga+g+v+ ++++++evavKk+r+ +e+         ++k+l+kl+hpnii+++G

Q: 128   LQWVGSGAQGAVFLGRFHGEEVAVKKVRDLKET---------DIKHLRKLKHPNIITFKG  178

         689**************************9999.........******************

S: 64    vcleepnlllvmeyveggsLsnvlhekskreidlevlvswalqiArGmaYLhseapkkii  123

         vc++ p+++++me++++g+L++vl++   r ++++ lv+w++ iA Gm+YLh +   kii

Q: 179   VCTQAPCYCILMEFCAQGQLYEVLRA--GRPVTPSLLVDWSMGIAGGMNYLHLH---KII  233

         **************************..99************************...9**

S: 124   hrdLksknvLlseekktlkicdFGtarelsk.stkmsaagtlawmaPEvlkeekvseksD  182

         hrdLks+               FGt++els+ stkms+agt+awmaPEv+++e+vsek+D

Q: 234   HRDLKSP---------------FGTSKELSDkSTKMSFAGTVAWMAPEVIRNEPVSEKVD  278

         *****96...............********99****************************

S: 183   vwSygvvLWelltrevPykdlselaiaykvalkglrlpipsscpeklkkLmkecwnedpe  242

         +wS+gvvLWellt+e+Pykd+++ ai+++v++++l+lp+psscp+ +k L+++cwn++p+

Q: 279   IWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPSSCPDGFKILLRQCWNSKPR  338

         ************************************************************

S: 243   kRpsfseivks  253

         +Rpsf++i+ +

Q: 339   NRPSFRQILLH  349

         ********876

Domain Sequence
(FASTA)

LQWVGSGAQG AVFLGRFHGE EVAVKKVRDL KETDIKHLRK LKHPNIITFK GVCTQAPCYC 60

ILMEFCAQGQ LYEVLRAGRP VTPSLLVDWS MGIAGGMNYL HLHKIIHRDL KSPFGTSKEL 120

SDKSTKMSFA GTVAWMAPEV IRNEPVSEKV DIWSFGVVLW ELLTGEIPYK DVDSSAIIWG 180

VGSNSLHLPV PSSCPDGFKI LLRQCWNSKP RNRPSFRQIL LH 222

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>