EKS-DIO-00022

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-DIO-00022

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/DYRK	436.5	4.8E-131	111	431	321

Status

Unreviewed

Ensembl Protein

ENSDORP00000005387

Gene Name

Dyrk1b

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSDORG00000005757	ENSDORP00000005387	ENSDORT00000005756

Organism

Dipodomys ordii

Protein Length

625

Protein Sequence
(FASTA)

MAVPPGHGPF SGFPGPQEHT QTLPDVRLLP RRLPLAFRDA TSAPLRKLSV DLIKTYKYIN 60

EVYYAKKKRR AQQVPPQDSS TKKEKRVLNH GYDDDNHDYI VRSGERWLER YEIDSLIGKG 120

SFGQVVKAYD HQTQELVAIK IIKNKKAFLN QAQIELRLLE LMNQHDTEMK YYIVHLKRHF 180

MFRNHLCLVF ELLSYNLYDL LRNTHFRGVS LNLTRKLAQQ LCTALLFLAT PELSIIHCDL 240

KPENILLCNP KRSAIKIVDF GSSCQLGQRI YQYIQSRFYR SPEVLLGTPY DLAIDMWSLG 300

CILVEMHTGE PLFSGSNEVD QMGRIVEVLG IPPAPMLEQA PKARKYFERL PGGGWTLRRT 360

KELRKDYQGP GTRRLQEVLG VQTGGPGGRR AGEPGHSPAD YLRFQDLVLR MLEYEPAARI 420

SPLGALQHGF FHRTDDATNT GPAGDASTSP APLDTCPSST TASSFSSSGG SSGSSSDNRA 480

YRYSNRYCGG PGPPISDCEM NSPQVLPSQP LRPWAGGDVP HKTHQAPTSA SSLPGTGAQL 540

PPQPRCLGRP PSPTSPPPPE LMDVSLVSPS DSPPHPAPAP QHPAASALRT RMTGGRPPLP 600

PPDDPASLGP RLGLRGVPQS TAASS 625

Nucleotide Sequence
(FASTA)

ATGGCCGTTC CACCAGGCCA TGGCCCCTTC TCTGGCTTCC CGGGGCCCCA GGAGCACACA 60

CAGACATTGC CTGATGTGCG GCTGCTGCCT CGGAGGCTGC CGCTGGCCTT CCGGGATGCC 120

ACTTCAGCCC CCCTGCGCAA GCTCTCTGTG GATCTCATCA AGACCTACAA GTACATCAAT 180

GAGGTGTACT ATGCGAAGAA GAAACGGCGG GCCCAGCAGG TGCCACCCCA GGACTCGAGC 240

ACCAAGAAGG AGAAGCGGGT CCTGAACCAT GGTTACGATG ACGACAACCA TGACTACATT 300

GTGCGCAGTG GCGAGCGCTG GCTGGAGCGC TACGAGATTG ACTCTCTGAT TGGCAAAGGC 360

TCCTTTGGCC AGGTGGTGAA AGCCTATGAT CATCAGACCC AGGAGCTGGT GGCCATCAAG 420

ATCATCAAGA ACAAAAAGGC CTTCCTGAAC CAGGCACAGA TCGAGTTGCG GCTGCTGGAG 480

CTGATGAACC AGCATGACAC AGAGATGAAG TACTACATAG TGCACCTGAA GCGGCACTTC 540

ATGTTCCGGA ACCACCTGTG CCTGGTGTTC GAGCTGCTGT CCTACAACCT GTATGACCTC 600

CTGCGAAACA CACACTTCCG AGGCGTCTCG CTGAACCTGA CCCGGAAGCT GGCACAGCAG 660

CTCTGTACAG CGTTGCTCTT CCTGGCCACG CCCGAACTCA GCATCATCCA CTGCGACCTC 720

AAGCCAGAGA ACATTCTCCT CTGCAACCCC AAGCGCAGTG CCATCAAGAT CGTGGACTTC 780

GGCAGCTCCT GCCAACTTGG CCAGCGGATC TACCAGTACA TCCAGAGCCG CTTCTACCGC 840

TCCCCGGAGG TGCTCCTGGG CACACCCTAC GACCTGGCCA TCGACATGTG GTCCCTGGGC 900

TGCATCCTGG TAGAGATGCA CACTGGGGAG CCCCTCTTCA GTGGCTCCAA TGAGGTGGAC 960

CAGATGGGCC GCATTGTGGA GGTGCTGGGC ATCCCACCAG CCCCCATGCT GGAGCAGGCC 1020

CCCAAGGCTC GCAAGTACTT TGAGCGGCTG CCTGGGGGTG GCTGGACCCT ACGCAGGACA 1080

AAGGAACTCA GGAAGGATTA CCAGGGCCCC GGGACACGGC GGCTGCAGGA GGTGCTGGGC 1140

GTGCAGACGG GCGGGCCCGG GGGCCGGCGG GCGGGGGAGC CGGGCCACAG CCCCGCCGAC 1200

TACCTCCGCT TCCAGGACCT GGTGCTGCGC ATGCTGGAGT ACGAGCCTGC CGCCCGCATC 1260

AGCCCCCTGG GCGCCCTGCA GCATGGCTTC TTCCACCGCA CGGACGACGC CACCAACACG 1320

GGCCCGGCAG GCGATGCCTC CACCTCGCCC GCGCCCCTCG ACACCTGCCC CTCCTCTACC 1380

ACCGCCAGCT CCTTCTCCAG CTCGGGAGGT TCCAGTGGCT CCTCCAGTGA CAACCGGGCC 1440

TACCGCTACA GCAACCGATA TTGTGGGGGC CCTGGGCCCC CAATCTCTGA CTGTGAGATG 1500

AACAGCCCCC AGGTTCTGCC CTCCCAGCCG CTGCGCCCCT GGGCAGGGGG CGATGTGCCC 1560

CACAAGACAC ATCAAGCCCC TACCTCTGCC TCATCACTGC CGGGGACCGG GGCCCAGTTA 1620

CCCCCCCAGC CCCGATGCCT TGGCCGTCCC CCATCACCAA CCTCACCACC ACCCCCGGAG 1680

CTGATGGATG TGAGCCTGGT GAGCCCTTCA GACTCCCCAC CTCACCCAGC GCCTGCCCCC 1740

CAGCACCCGG CTGCCTCAGC CCTCCGGACT CGGATGACAG GAGGTCGTCC ACCTCTCCCA 1800

CCCCCTGATG ACCCTGCCTC TCTGGGGCCT CGCCTGGGCC TCCGTGGTGT ACCCCAGAGC 1860

ACAGCAGCCA GCTCATGA 1878

Domain Profile

S: 1     yevlevigkGsfgqVvkaldkktkeivaikiiknkkrfarqaqeEveiLeklnkkdkeek  60

         ye++++igkGsfgqVvka+d++t+e vaikiiknkk+f++qaq+E+++Le +n++d+e+k

Q: 111   YEIDSLIGKGSFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMK  170

         9***********************************************************

S: 61    ynvvrllelfvfrnhlclvfellsqnLyellkknkfsglslklvrklaqqilkaLklLk.  119

         y++v+l+++f+frnhlclvfells+nLy+ll++++f+g+sl+l+rklaqq+++aL +L+

Q: 171   YYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKLAQQLCTALLFLAt  230

         **********************************************************99

S: 120   .elkiiHaDlKPeNillvekkrsevkviDFGsssavsqkeiytyiqsrfYraPEiilglk  178

          el+iiH+DlKPeNill+++krs++k++DFGss++  q+ iy+yiqsrfYr+PE++lg++

Q: 231   pELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQR-IYQYIQSRFYRSPEVLLGTP  289

         99*************************************.********************

S: 179   ydeaiDmWSlGcvlaElftGkpLfpGenevdqlalivevlglppekllekakkakkfftk  238

         yd aiDmWSlGc+l+E++tG+pLf+G+nevdq+  ivevlg+pp+ +le+a ka+k+f++

Q: 290   YDLAIDMWSLGCILVEMHTGEPLFSGSNEVDQMGRIVEVLGIPPAPMLEQAPKARKYFER  349

         ************************************************************

S: 239   keapkyilktk.........ksdrkkklvlnvkkaakkrkaplskelgealkekedkl.f  288

              ++l+++          ++r+ ++vl+v++ +     p+ +++ge+ ++ +d+l f

Q: 350   LPGGGWTLRRTkelrkdyqgPGTRRLQEVLGVQTGG-----PGGRRAGEPGHSPADYLrF  404

         ********9997888888777778888888887777.....99*****************

S: 289   kdllkrmleldpakRitpkealkhpfv  315

         +dl+ rmle++pa+Ri+p  al+h f+

Q: 405   QDLVLRMLEYEPAARISPLGALQHGFF  431

         *************************97

Domain Sequence
(FASTA)

YEIDSLIGKG SFGQVVKAYD HQTQELVAIK IIKNKKAFLN QAQIELRLLE LMNQHDTEMK 60

YYIVHLKRHF MFRNHLCLVF ELLSYNLYDL LRNTHFRGVS LNLTRKLAQQ LCTALLFLAT 120

PELSIIHCDL KPENILLCNP KRSAIKIVDF GSSCQLGQRI YQYIQSRFYR SPEVLLGTPY 180

DLAIDMWSLG CILVEMHTGE PLFSGSNEVD QMGRIVEVLG IPPAPMLEQA PKARKYFERL 240

PGGGWTLRRT KELRKDYQGP GTRRLQEVLG VQTGGPGGRR AGEPGHSPAD YLRFQDLVLR 300

MLEYEPAARI SPLGALQHGF F 321

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dasypus novemcinctus"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Schizosaccharomyces pombe"; ?>