EKS-EQC-00463

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-EQC-00463

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMK2	587.2	3.9E-177	14	272	259

Status

Unreviewed

Ensembl Protein

ENSECAP00000001198

UniProt Accession

F6TEC0;

Protein Name

Protein Synonyms/Alias

Gene Name

CAMK2G

Gene Synonyms/Alias

CAMK2G;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSECAG00000000031	ENSECAP00000001198	ENSECAT00000001588

Organism

Equus caballus

Functional Description

Protein Length

556

Protein Sequence
(FASTA)

MATTATCTRF TDDYQLFEEL GKGAFSVVRR CVKKTSTQEY AAKIINTKKL SARDHQKLER 60

EARICRLLKH PNIVRLHDSI SEEGFHYLVF DLVTGGELFE DIVAREYYSE ADASHCIHQI 120

LESVNHIHQH DIVHRDLKPE NLLLASKCKG AAVKLADFGL AIEVQGEQQA WFGFAGTPGY 180

LSPEVLRKDP YGKPVDIWAC GVILYILLVG YPPFWDEDQH KLYQQIKAGA YDFPSPEWDT 240

VTPEAKNLIN QMLTINPAKR ITADQALKHP WVCQRSTVAS MMHRQETVEC LRKFNARRKL 300

KGAILTTMLV SRNFSAAKSL LNKKSDGGVK PQSNNKNSLV SPAQEPAPLQ TAMEPQTTVV 360

HNATDGIKGS TESCNTTTED EDLKAAPLRT GNGSSVPEGR SSRDRTAPSA GMQPQPSLCS 420

SAMRKQEIIK ITEQLIEAIN NGDFEAYTKI CDPGLTSFEP EALGNLVEGM DFHKFYFENL 480

LSKNSKPIHT TILNPHVHVI GEDAACIAYI RLTQYIDGQG RPRTSQSEET RVWHRRDGKW 540

LNVHYHCSGA PAAPLQ 556

Nucleotide Sequence
(FASTA)

ATGGCCACCA CCGCCACCTG CACCCGCTTC ACCGACGACT ACCAGCTCTT CGAGGAGCTC 60

GGCAAGGGTG CTTTCTCTGT GGTCCGCAGG TGTGTGAAGA AAACCTCCAC GCAGGAGTAT 120

GCAGCAAAAA TCATCAATAC CAAGAAGTTG TCTGCCCGAG ATCACCAGAA ACTAGAACGT 180

GAAGCCCGGA TATGCCGACT TTTAAAACAT CCAAACATTG TGCGCCTCCA TGACAGTATT 240

TCTGAAGAAG GGTTTCACTA CCTCGTGTTT GACCTTGTTA CTGGAGGTGA GCTGTTTGAA 300

GACATTGTGG CCAGAGAGTA CTACAGTGAA GCTGATGCCA GCCACTGTAT ACATCAGATT 360

CTGGAGAGTG TTAACCACAT TCACCAGCAT GACATTGTCC ACCGGGACCT GAAGCCTGAG 420

AACCTGCTAC TGGCCAGTAA ATGCAAGGGT GCCGCCGTCA AGCTGGCTGA TTTTGGCCTA 480

GCCATTGAAG TACAGGGAGA GCAGCAGGCT TGGTTTGGTT TTGCTGGCAC CCCAGGTTAC 540

TTGTCCCCTG AGGTCTTGAG GAAAGATCCC TATGGAAAAC CTGTGGATAT CTGGGCCTGC 600

GGGGTCATCC TGTATATCCT CCTGGTGGGA TACCCTCCCT TCTGGGATGA GGATCAGCAC 660

AAGCTGTATC AGCAGATCAA GGCTGGAGCC TATGATTTCC CATCACCCGA GTGGGACACC 720

GTGACTCCTG AAGCCAAGAA TTTGATCAAC CAGATGCTGA CCATAAACCC TGCAAAGCGC 780

ATCACAGCTG ACCAGGCTCT CAAGCACCCA TGGGTCTGCC AACGATCCAC AGTGGCATCC 840

ATGATGCATC GTCAAGAGAC AGTGGAGTGC TTGCGCAAGT TCAACGCCCG GAGAAAACTG 900

AAGGGTGCCA TCCTCACGAC CATGCTTGTC TCCAGGAACT TTTCAGCTGC CAAAAGCCTA 960

TTAAACAAGA AGTCAGACGG TGGTGTGAAG CCACAGAGCA ACAACAAAAA CAGTCTCGTA 1020

AGCCCAGCCC AAGAGCCCGC GCCCTTGCAG ACGGCCATGG AACCTCAAAC CACTGTGGTG 1080

CACAATGCTA CAGATGGGAT CAAGGGCTCC ACAGAGAGCT GCAACACCAC CACAGAAGAT 1140

GAGGACCTCA AAGCTGCCCC GCTCCGCACT GGGAATGGCA GCTCGGTGCC TGAAGGACGG 1200

AGCTCCCGGG ACAGAACAGC CCCCTCTGCA GGCATGCAGC CCCAGCCTTC TCTCTGCTCC 1260

TCAGCCATGC GAAAACAGGA GATCATTAAG ATCACAGAAC AACTGATTGA GGCCATCAAC 1320

AATGGGGACT TTGAGGCCTA CACGAAGATT TGTGATCCAG GCCTCACTTC CTTTGAGCCT 1380

GAGGCCCTTG GTAACCTCGT GGAGGGGATG GATTTCCATA AGTTTTACTT TGAGAATCTC 1440

CTATCTAAGA ACAGCAAGCC CATCCACACC ACCATCCTGA ACCCACACGT CCATGTGATT 1500

GGGGAGGACG CAGCTTGCAT CGCCTACATC CGCCTCACCC AGTACATCGA TGGGCAGGGT 1560

CGGCCTCGCA CCAGCCAGTC GGAGGAGACC CGGGTCTGGC ACCGCCGGGA TGGCAAGTGG 1620

CTCAATGTCC ACTATCACTG CTCAGGGGCC CCTGCCGCAC CGCTGCAGTG A 1671

Domain Profile

S: 1     yqlfeelgkgafsvvrrcvkvttgqeyaakiintkklsardhqklerearicrllkhpni  60

         yqlfeelgkgafsvvrrcvk+t++qeyaakiintkklsardhqklerearicrllkhpni

Q: 14    YQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNI  73

         9***********************************************************

S: 61    vrlhdsiseegfhylvfdlvtggelfedivareyyseadashciqqilesvlhihqngvv  120

         vrlhdsiseegfhylvfdlvtggelfedivareyyseadashci+qilesv+hihq+++v

Q: 74    VRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIV  133

         ************************************************************

S: 121   hrdlkpenlllaskakgaavkladfglaievqgdqqawfgfagtpgylspevlrkdpygk  180

         hrdlkpenlllask+kgaavkladfglaievqg+qqawfgfagtpgylspevlrkdpygk

Q: 134   HRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGK  193

         ************************************************************

S: 181   pvdlwacgvilyillvgyppfwdedqhrlyqqikagaydfpspewdtvtpeakdlinkml  240

         pvd+wacgvilyillvgyppfwdedqh+lyqqikagaydfpspewdtvtpeak+lin+ml

Q: 194   PVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQML  253

         ************************************************************

S: 241   tinpakritadealkhpwi  259

         tinpakritad+alkhpw+

Q: 254   TINPAKRITADQALKHPWV  272

         ******************8

Domain Sequence
(FASTA)

YQLFEELGKG AFSVVRRCVK KTSTQEYAAK IINTKKLSAR DHQKLEREAR ICRLLKHPNI 60

VRLHDSISEE GFHYLVFDLV TGGELFEDIV AREYYSEADA SHCIHQILES VNHIHQHDIV 120

HRDLKPENLL LASKCKGAAV KLADFGLAIE VQGEQQAWFG FAGTPGYLSP EVLRKDPYGK 180

PVDIWACGVI LYILLVGYPP FWDEDQHKLY QQIKAGAYDF PSPEWDTVTP EAKNLINQML 240

TINPAKRITA DQALKHPWV 259

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004683	; F:calmodulin-dependent protein kinase activity
GO:0006816	; P:calcium ion transport
GO:0000082	; P:G1/S transition of mitotic cell cycle
GO:0046777	; P:protein autophosphorylation

KEGG

ecb:100064138

;

InterPros

IPR020636	; Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR013543	; Ca/CaM-dep_prot_kinase-assoc.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF08332	; CaMKII_AD; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013