EPS-EQC-00063

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-EQC-00063

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Asp-Based PTP/FCP	114.8	4.2E-33	155	302	148

Status

Unreviewed

Ensembl Protein

ENSECAP00000001940

UniProt Accession

F6W8S4;

Protein Name

Protein Synonyms/Alias

Gene Name

TIMM50

Gene Synonyms/Alias

TIMM50;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSECAG00000001235	ENSECAP00000001940	ENSECAT00000002710

Organism

Equus caballus

Functional Description

Protein Length

360

Protein Sequence
(FASTA)

WRQRKMAASA ALLLRLRSGL RLGARGLCAR LATPPPRASD QAAEIGSRAG TKAQAQGPQQ 60

QRGTEGPSYA KKVALWLAGL LGAGGTVSVV YIFGNNSVDE TGAKIPDEFD NDPILVQQLR 120

RTYKYFKDYR QMIIEPTSPC LLPDPLREPY YQPPYTLVLE LTGVLLHPEW SLATGWRFKK 180

RPGIETLFQQ LAPLYEIVIF TSETGMTAFP LIDSVDPHGF ISYRLFRDAT RYMDGHHVKD 240

ISCLNRDPAR VVVVDCKKEA FRLQPYNGVA LRPWDGNSDD RVLLDLSAFL KTIALNSVED 300

VRTVLEHYAL EDDPLEAFKQ RQSRLEQEEQ QRLAELSKSS KQNLFFGSLT SRLWPRSKQP 360

Nucleotide Sequence
(FASTA)

TGGCGTCAGC GCAAGATGGC GGCCTCGGCG GCGCTGCTCC TGCGCTTGCG AAGCGGGCTC 60

CGGCTCGGCG CGCGGGGACT GTGCGCGAGG CTGGCGACGC CGCCTCCCCG GGCCTCGGAC 120

CAGGCAGCGG AAATCGGGAG CCGAGCTGGC ACAAAGGCCC AGGCCCAGGG GCCACAGCAG 180

CAGCGGGGCA CGGAGGGTCC CAGCTACGCC AAGAAAGTTG CCCTCTGGCT TGCTGGGCTG 240

CTCGGTGCCG GTGGAACCGT GAGCGTTGTC TATATCTTTG GAAACAACTC TGTGGATGAA 300

ACTGGTGCCA AGATTCCCGA TGAATTCGAC AATGATCCAA TCCTGGTACA GCAGTTGCGC 360

CGGACATACA AATATTTCAA AGATTATAGA CAGATGATCA TCGAGCCCAC CAGCCCCTGC 420

CTTCTCCCAG ACCCTCTGCG GGAGCCGTAC TACCAGCCGC CCTACACCCT GGTCTTGGAG 480

CTCACTGGCG TCCTCCTGCA CCCTGAGTGG TCGCTGGCCA CGGGCTGGAG GTTTAAGAAG 540

CGTCCGGGCA TTGAGACCTT ATTCCAGCAG CTGGCCCCTT TGTATGAAAT CGTCATCTTC 600

ACGTCGGAGA CTGGCATGAC TGCGTTTCCA CTCATCGACA GCGTGGACCC CCACGGCTTC 660

ATCTCCTACC GCCTGTTCCG GGACGCCACA AGATACATGG ATGGGCACCA TGTTAAGGAC 720

ATTTCCTGTC TGAATCGGGA CCCGGCCCGT GTGGTAGTCG TGGACTGCAA GAAGGAAGCC 780

TTCCGCCTGC AGCCCTACAA TGGTGTCGCC CTGCGGCCCT GGGACGGGAA CTCCGATGAC 840

CGTGTCTTGT TGGACCTGTC TGCCTTCCTC AAGACCATTG CCCTGAACAG CGTGGAGGAT 900

GTGCGGACGG TGCTGGAGCA CTACGCCCTG GAGGACGACC CGCTGGAGGC TTTCAAACAG 960

CGGCAAAGCC GGCTGGAACA GGAGGAGCAG CAGCGCCTGG CCGAGCTCTC CAAATCCAGC 1020

AAGCAGAACC TCTTCTTCGG CTCTCTCACC AGCCGCCTGT GGCCTCGATC CAAACAGCCC 1080

TGA 1083

Domain Profile

S: 1     ktLVLDLDetLvhsksekdeeeektkasvkkRPgldeFLkelskayevviftasskeyad  60

         +tLVL+L ++L+h +++       t +++kkRPg + ++++l+  ye+vift+++ ++a

Q: 155   YTLVLELTGVLLHPEWSLA-----TGWRFKKRPGIETLFQQLAPLYEIVIFTSETGMTAF  209

         69*************9776.....9***********************************

S: 61    avldkldpkkklfkkrlyresctlengkyvKdLsllgrdlskvvivDdsprsfelqpdnl  120

         +++d +dp + ++++rl+r+ +++ +g++vKd+s l+rd  +vv+vD ++++f+lqp+n+

Q: 210   PLIDSVDP-HGFISYRLFRDATRYMDGHHVKDISCLNRDPARVVVVDCKKEAFRLQPYNG  268

         ********.6799**************99*******************************

S: 121   ipiepfygdsdkdtellkllpfleale.ks.ddvr  153

         + ++p+ g+ ++d+ ll+l+ fl+ ++ +s +dvr

Q: 269   VALRPWDGN-SDDRVLLDLSAFLKTIAlNSvEDVR  302

         ********9.999**********999986669997

Domain Sequence
(FASTA)

YTLVLELTGV LLHPEWSLAT GWRFKKRPGI ETLFQQLAPL YEIVIFTSET GMTAFPLIDS 60

VDPHGFISYR LFRDATRYMD GHHVKDISCL NRDPARVVVV DCKKEAFRLQ PYNGVALRPW 120

DGNSDDRVLL DLSAFLKTIA LNSVEDVR 148

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Felis catus"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005744	; C:mitochondrial inner membrane presequence translocase complex
GO:0016607	; C:nuclear speck
GO:0004722	; F:protein serine/threonine phosphatase activity
GO:0004725	; F:protein tyrosine phosphatase activity
GO:0043021	; F:ribonucleoprotein complex binding
GO:0007006	; P:mitochondrial membrane organization
GO:0001836	; P:release of cytochrome c from mitochondria

KEGG

InterPros

IPR023214	; HAD-like_dom.
IPR004274	; NIF.

Pfam

PF03031

; NIF; 1.

SMARTs

SM00577

; CPDc; 1.

Prosites

PS50969

; FCP1; 1.

Prints

Created Date

20-Feb-2013