EKS-EQC-00015

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-EQC-00015

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/PHK	525.9	2.2E-158	23	291	269

Status

Unreviewed

Ensembl Protein

ENSECAP00000004911

UniProt Accession

F6U196;

Protein Name

Protein Synonyms/Alias

Gene Name

PHKG1

Gene Synonyms/Alias

PHKG1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSECAG00000005983	ENSECAP00000004911	ENSECAT00000006836

Organism

Equus caballus

Functional Description

Protein Length

390

Protein Sequence
(FASTA)

ELSMTRDEAL PDSYSAQGFY ENYEPKEILG RGVSSVVRRC IHKPTCQEYA VKIIDITGGG 60

SFSSEEVREL REATLKEVDI LRKVSGHPNI IQLKDTYETN TFFFLVFDLM KRGELFDYLT 120

EKVTLSEKET RKIMRALLEV ICALHKLNIV HRDLKPENIL LDDNMNIKLT DFGFSCQLEP 180

GEKLREVCGT PSYLAPEIIE CSMNDDHPGY GKEVDMWSTG VIMYTLLAGS PPFWHRKQML 240

MLRMIMSGNY QFGSPEWDDY SDTVKDLVSR FLVVSPQGRC SAEEALAHPF FQQYVVEEVR 300

HFSPRGKFKV ICLTVLASVR IYYQYRRVKP VTREIVIRDP YALRPLRRLI DAYAFRIYGH 360

WVKKGQQQNR AALFENTPKA VLLSLAEEDY 390

Nucleotide Sequence
(FASTA)

GAGCTGAGCA TGACCCGAGA CGAGGCATTG CCGGACTCGT ATTCTGCACA GGGCTTCTAC 60

GAGAACTACG AGCCCAAGGA GATCCTGGGC AGGGGTGTTA GCAGTGTTGT CAGGCGCTGC 120

ATCCACAAGC CCACATGCCA GGAGTATGCT GTGAAGATCA TCGACATCAC TGGTGGGGGC 180

AGCTTCAGCT CCGAGGAGGT GCGGGAGCTG CGAGAGGCCA CGTTGAAGGA GGTGGACATC 240

CTGCGCAAGG TTTCAGGGCA CCCCAACATC ATACAGCTGA AGGACACTTA TGAGACCAAC 300

ACTTTCTTCT TCTTGGTGTT TGATCTGATG AAGAGAGGGG AGCTCTTTGA TTACCTCACT 360

GAGAAGGTCA CCCTGAGTGA GAAGGAAACC AGAAAGATCA TGAGAGCCCT GTTGGAGGTG 420

ATCTGCGCCT TGCACAAACT CAACATCGTG CATCGGGATC TGAAGCCCGA GAATATCCTC 480

TTGGATGATA ACATGAACAT CAAGCTCACA GACTTTGGCT TTTCCTGCCA GCTGGAGCCA 540

GGAGAGAAGC TGCGAGAGGT CTGTGGGACC CCCAGTTACC TGGCCCCTGA GATCATTGAG 600

TGCTCCATGA ATGATGATCA CCCAGGCTAC GGGAAGGAGG TGGACATGTG GAGTACAGGG 660

GTCATCATGT ACACCCTGCT GGCTGGCTCC CCGCCCTTTT GGCACCGGAA GCAGATGCTG 720

ATGCTGAGGA TGATCATGAG TGGCAACTAC CAGTTTGGCT CACCTGAATG GGATGATTAC 780

TCAGACACAG TGAAGGACTT GGTTTCCCGC TTCTTGGTGG TGAGCCCCCA GGGCCGCTGT 840

TCAGCAGAAG AGGCCTTAGC ACATCCCTTC TTCCAGCAGT ATGTGGTTGA AGAAGTACGT 900

CACTTCAGCC CCCGGGGGAA GTTCAAGGTG ATCTGTCTAA CAGTGCTGGC CTCAGTGCGG 960

ATCTACTACC AGTACCGCCG GGTGAAGCCT GTGACCCGGG AGATTGTCAT CCGAGATCCC 1020

TATGCCCTCC GGCCTCTGCG CCGACTCATC GATGCCTATG CTTTCCGAAT ATATGGCCAC 1080

TGGGTAAAGA AGGGGCAGCA GCAGAACCGG GCTGCCCTCT TTGAGAACAC ACCCAAGGCC 1140

GTGCTCCTCT CCTTGGCTGA GGAGGACTAC TGA 1173

Domain Profile

S: 1     yepkeilGrGvssvvrrciekatgqefavkiidvs.aeklseeevkelreatlkeveilr  59

         yepkeilGrGvssvvrrci+k+t+qe+avkiid++ ++++s+eev+elreatlkev+ilr

Q: 23    YEPKEILGRGVSSVVRRCIHKPTCQEYAVKIIDITgGGSFSSEEVRELREATLKEVDILR  82

         9**********************************899**********************

S: 60    qvsGhpsiiklkdvyesssflflvfdlmkkGelfdyltekvtlseketrkimralleave  119

         +vsGhp+ii+lkd+ye+++f+flvfdlmk+Gelfdyltekvtlseketrkimralle+++

Q: 83    KVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRALLEVIC  142

         ************************************************************

S: 120   ylhaknivhrdlkpenillddneniklsdfGfstqleeGeklrelcGtpgylapeilkcs  179

          lh+ nivhrdlkpenillddn+nikl+dfGfs+qle+Geklre+cGtp+ylapei++cs

Q: 143   ALHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGEKLREVCGTPSYLAPEIIECS  202

         ************************************************************

S: 180   mdeeapGyskevdlwalGvilytllaGsppfwhrkqllmlrlimeGkyqftspewddise  239

         m++++pGy+kevd+w++Gvi+ytllaGsppfwhrkq+lmlr+im+G+yqf+spewdd+s+

Q: 203   MNDDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWDDYSD  262

         ************************************************************

S: 240   evkdliskllvvdpekrltaeealahpff  268

         +vkdl+s++lvv p+ r++aeealahpff

Q: 263   TVKDLVSRFLVVSPQGRCSAEEALAHPFF  291

         ****************************8

Domain Sequence
(FASTA)

YEPKEILGRG VSSVVRRCIH KPTCQEYAVK IIDITGGGSF SSEEVRELRE ATLKEVDILR 60

KVSGHPNIIQ LKDTYETNTF FFLVFDLMKR GELFDYLTEK VTLSEKETRK IMRALLEVIC 120

ALHKLNIVHR DLKPENILLD DNMNIKLTDF GFSCQLEPGE KLREVCGTPS YLAPEIIECS 180

MNDDHPGYGK EVDMWSTGVI MYTLLAGSPP FWHRKQMLML RMIMSGNYQF GSPEWDDYSD 240

TVKDLVSRFL VVSPQGRCSA EEALAHPFF 269

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005964	; C:phosphorylase kinase complex
GO:0005524	; F:ATP binding
GO:0004689	; F:phosphorylase kinase activity
GO:0005978	; P:glycogen biosynthetic process

KEGG

InterPros

IPR020636	; Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR011009	; Kinase-like_dom.
IPR002291	; Phosph_kin_gamma.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

PR01049

; PHOSPHBKNASE.

Created Date

20-Feb-2013