EPS-EQC-00120

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-EQC-00120

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PDP	395.4	7.1E-119	229	443	215

Status

Unreviewed

Ensembl Protein

ENSECAP00000004474

UniProt Accession

F7A4F3;

Protein Name

Protein Synonyms/Alias

Gene Name

PDP2

Gene Synonyms/Alias

PDP2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSECAG00000006359	ENSECAP00000004474	ENSECAT00000006330

Organism

Equus caballus

Functional Description

Protein Length

532

Protein Sequence
(FASTA)

FRMSSSVSYW ILNSARNSIA TLQGGGRLYS RCASNWNKSK WRLFSPALAT LKNDAPCGSF 60

ALQKAYRHTS TEEDDFHLQL SPEQVNEVLR AGESAHKILD LVNGVPNSVL RFESNQLAAN 120

SPVEDRRGVA SCLQTNGLMF GIFDGHGGHA CAQAVSERLF YYVAVSLMSQ QTLEQMEGAM 180

ESMKPLLPIL QWLKHPGDSI YKDVTSMHLD HLRVYWQELL DVHMEMGLNI EEALMYSFQR 240

LDSDISLEIQ APLEDEMTRN LSLQVAFSGA TACMAHVDGV HLHVANAGDC RAILGVQEDN 300

GMWSCLPLTR DHNAWNQAEL SRLKKEHPAS EDKTVIMDDR LLGILMPCRA FGDVQLKWSK 360

ELQRSVLERG FDTEALNIYQ FTSPHYYTPP YLTAKPEVTY HRLRPQDKFL VLASDGLWDM 420

LGNEDVVRLV VEHLAEAGRH KPDLAQRPAN LGLMQSLLLQ RKAQGLQAAD QNAATHLIRH 480

AIGSNEYGEM EPERLTAMLT LPEDLARMYR DDITVTVVYF NSDSIDACYK GD 532

Nucleotide Sequence
(FASTA)

TTCAGAATGT CAAGTTCTGT GTCCTACTGG ATCTTAAATT CTGCAAGGAA TAGCATTGCC 60

ACATTACAAG GAGGTGGACG TTTATATTCA AGGTGTGCCT CAAATTGGAA TAAATCAAAA 120

TGGAGGCTCT TTTCCCCGGC ACTGGCCACT CTAAAAAATG ATGCACCATG TGGTAGCTTT 180

GCTCTGCAGA AAGCCTACAG ACACACATCA ACGGAGGAAG ACGATTTCCA CTTACAGCTC 240

AGCCCTGAGC AGGTAAATGA AGTGCTTCGA GCTGGTGAGT CTGCCCACAA GATTCTTGAC 300

CTGGTCAACG GAGTTCCAAA TTCCGTGTTG CGGTTTGAGA GCAACCAGCT GGCTGCCAAC 360

TCCCCAGTGG AGGACCGACG AGGTGTGGCC TCCTGCCTGC AGACCAATGG GCTCATGTTT 420

GGCATCTTTG ATGGACATGG TGGCCATGCA TGTGCTCAAG CAGTGAGCGA ACGGCTCTTC 480

TACTATGTGG CAGTGTCACT GATGTCCCAG CAGACCCTGG AGCAGATGGA GGGAGCAATG 540

GAAAGCATGA AGCCCCTGCT GCCCATCCTG CAGTGGCTCA AGCATCCAGG GGACAGTATC 600

TATAAGGATG TCACATCCAT GCACCTTGAT CACCTCCGTG TCTACTGGCA GGAGCTGCTT 660

GACGTGCACA TGGAAATGGG ACTGAACATT GAGGAAGCAT TAATGTACTC CTTCCAGAGA 720

CTGGATTCTG ACATCTCGCT GGAAATCCAG GCCCCCCTGG AAGATGAGAT GACAAGGAAC 780

CTTTCACTCC AGGTCGCTTT CTCCGGGGCA ACAGCTTGCA TGGCCCATGT CGACGGAGTT 840

CACTTGCATG TGGCAAACGC AGGTGACTGT CGGGCCATCC TTGGTGTCCA GGAGGACAAT 900

GGCATGTGGT CTTGTCTTCC CCTCACCCGC GATCACAATG CCTGGAACCA GGCTGAGTTG 960

TCACGGCTAA AGAAGGAGCA TCCTGCGTCA GAGGACAAGA CAGTCATCAT GGATGACAGG 1020

CTGCTGGGCA TCCTCATGCC CTGCAGGGCC TTTGGGGACG TCCAGCTAAA GTGGAGCAAG 1080

GAGCTGCAAC GCAGTGTCCT AGAGAGGGGC TTTGACACTG AGGCCCTCAA CATTTACCAG 1140

TTCACCTCCC CGCACTACTA TACTCCACCC TACCTGACTG CCAAGCCTGA GGTCACATAC 1200

CACAGACTGA GGCCCCAGGA TAAGTTCCTC GTGCTGGCCT CAGACGGCCT GTGGGACATG 1260

CTGGGCAATG AGGATGTAGT GAGGCTGGTG GTGGAGCACC TGGCTGAAGC TGGTCGGCAC 1320

AAGCCGGACC TGGCCCAGAG ACCTGCCAAC CTGGGCCTCA TGCAGAGCCT GCTGCTGCAG 1380

AGGAAAGCCC AGGGGCTCCA GGCTGCCGAC CAGAATGCAG CCACACATCT GATCAGACAT 1440

GCCATTGGGA GCAACGAGTA TGGGGAGATG GAGCCGGAGC GGCTGACGGC CATGCTGACG 1500

TTGCCGGAGG ATTTGGCGAG GATGTACAGG GATGACATCA CTGTCACTGT GGTGTATTTT 1560

AACTCAGACT CAATTGATGC ATGTTACAAG GGAGATTAA 1599

Domain Profile

S: 4     dvkealvnafkrldedisleaqvsdedevlrylvlrvalsGataclahvdGvdlhvantG  63

         +++eal+++f+rld+disle+q++ ede++r+l+l+va+sGatac+ahvdGv+lhvan+G

Q: 229   NIEEALMYSFQRLDSDISLEIQAPLEDEMTRNLSLQVAFSGATACMAHVDGVHLHVANAG  288

         79**********************************************************

S: 64    dsravlGvqeedgswsavklsrdhnaqneselerlkaehpkseaktvikedrllgllipl  123

         d+ra+lGvqe++g+ws+++l+rdhna+n++el+rlk+ehp se+ktvi++drllg+l+p+

Q: 289   DCRAILGVQEDNGMWSCLPLTRDHNAWNQAELSRLKKEHPASEDKTVIMDDRLLGILMPC  348

         ************************************************************

S: 124   rafGdvkfkwskelqkrvvesgfdvladneykfiapnyytppyltaepevtyhrlrpqdk  183

         rafGdv++kwskelq++v+e+gfd++a+n+y+f++p+yytppylta+pevtyhrlrpqdk

Q: 349   RAFGDVQLKWSKELQRSVLERGFDTEALNIYQFTSPHYYTPPYLTAKPEVTYHRLRPQDK  408

         ************************************************************

S: 184   flvlasdGlwdllsredvvrlvgeylaeadttlte  218

         flvlasdGlwd+l +edvvrlv+e+laea  ++ +

Q: 409   FLVLASDGLWDMLGNEDVVRLVVEHLAEAGRHKPD  443

         *****************************999876

Domain Sequence
(FASTA)

NIEEALMYSF QRLDSDISLE IQAPLEDEMT RNLSLQVAFS GATACMAHVD GVHLHVANAG 60

DCRAILGVQE DNGMWSCLPL TRDHNAWNQA ELSRLKKEHP ASEDKTVIMD DRLLGILMPC 120

RAFGDVQLKW SKELQRSVLE RGFDTEALNI YQFTSPHYYT PPYLTAKPEV TYHRLRPQDK 180

FLVLASDGLW DMLGNEDVVR LVVEHLAEAG RHKPD 215

Keyword

Complete proteome; Hydrolase; Magnesium; Metal-binding; Protein phosphatase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005739	; C:mitochondrion
GO:0046872	; F:metal ion binding
GO:0004722	; F:protein serine/threonine phosphatase activity
GO:0006470	; P:protein dephosphorylation

KEGG

InterPros

IPR001932	; PP2C-like.
IPR000222	; PP2C_Mn2_Asp60_BS.
IPR015655	; Protein_Pase_2C.

Pfam

PF00481

; PP2C; 1.

SMARTs

SM00331	; PP2C_SIG; 1.
SM00332	; PP2Cc; 1.

Prosites

PS01032

; PP2C; 1.

Prints

Created Date

20-Feb-2013