EKS-EQC-00408

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-EQC-00408

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/DAPK	418.9	7.8E-126	1	253	253

Status

Unreviewed

Ensembl Protein

ENSECAP00000005206

UniProt Accession

F7CSH1;

Protein Name

Protein Synonyms/Alias

Gene Name

STK17A

Gene Synonyms/Alias

STK17A;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSECAG00000006915	ENSECAP00000005206	ENSECAT00000007186

Organism

Equus caballus

Functional Description

Protein Length

346

Protein Sequence
(FASTA)

RGKFAVVRKC IEKDSGKEFA AKFMRKRRKG QDCRMEIIHE IAVLELAQDN PWVINLHEVY 60

ETPSEMILVL EYAAGGEIFD QCVADREEAF KEKDVQRLMR QILEGVSFLH AHDVVHLDLK 120

PQNILLTSES PLGDIKIVDF GLSRIMKNSE ELREIMGTPE YVAPEILSYD PISMATDMWS 180

IGVLTYVMLT GISPFLGDNK QETFLNISQM NLSYSEEEFD AVSESAVDFI KTLLVKKPED 240

RATAEECLNH PWLTPSSSQD PSVKVKGAEE AAGALPEGDS LPEISSDTQT PDAEEAVAAE 300

ELIVVTSYTL GQCRQSEKEK MEQKAISKRF KFEEPLLQEI PGEFIY 346

Nucleotide Sequence
(FASTA)

AGGGGCAAAT TTGCAGTGGT GAGGAAATGT ATAGAGAAAG ATTCTGGAAA AGAATTTGCA 60

GCAAAGTTCA TGAGAAAAAG AAGAAAAGGC CAGGATTGTC GGATGGAAAT AATTCATGAG 120

ATTGCCGTAC TTGAACTAGC ACAGGACAAT CCGTGGGTCA TTAATTTACA TGAAGTCTAT 180

GAAACTCCGT CAGAAATGAT CTTAGTTCTG GAATATGCCG CTGGGGGTGA AATCTTTGAC 240

CAGTGTGTTG CAGACAGAGA AGAAGCCTTT AAAGAAAAAG ATGTTCAAAG ACTCATGAGG 300

CAGATTTTAG AAGGCGTTAG CTTTTTACAC GCTCATGACG TAGTTCATCT TGATTTGAAG 360

CCTCAGAATA TTCTGCTGAC AAGTGAATCT CCACTGGGTG ACATTAAGAT AGTTGATTTT 420

GGTCTTTCAA GAATAATGAA GAACAGTGAA GAGCTCCGAG AAATCATGGG TACTCCTGAG 480

TATGTGGCTC CTGAAATTCT TAGTTATGAT CCCATCAGCA TGGCGACAGA TATGTGGAGC 540

ATTGGAGTGT TAACGTACGT CATGCTGACA GGAATATCGC CTTTCTTAGG TGATAATAAA 600

CAAGAAACGT TCCTAAACAT CTCACAGATG AACTTAAGTT ACTCTGAGGA AGAATTCGAT 660

GCTGTGTCTG AGTCAGCTGT TGACTTCATC AAGACACTTT TAGTTAAGAA ACCTGAAGAC 720

CGAGCCACCG CTGAAGAGTG TCTAAACCAC CCGTGGTTGA CCCCGAGCAG CAGTCAGGAT 780

CCTTCCGTCA AGGTGAAAGG GGCAGAAGAA GCAGCAGGTG CCCTCCCGGA AGGTGATTCT 840

CTGCCGGAAA TTAGTTCAGA CACTCAGACA CCAGACGCTG AGGAGGCCGT TGCAGCAGAG 900

GAGTTAATCG TGGTCACTTC ATATACTTTA GGACAATGCA GACAGTCTGA GAAAGAGAAA 960

ATGGAGCAAA AGGCCATTTC CAAACGATTT AAATTTGAGG AACCCTTGCT ACAGGAAATT 1020

CCAGGAGAAT TTATCTACTG A 1041

Domain Profile

S: 9     sGkfavvrkcrekstGkeyaakflkkrrlkssrrgvsreeierevavlkeirsepnvinl  68

         +Gkfavvrkc+ek++Gke+aakf++krr    +++++r+ei +e+avl++++++p+vinl

Q: 1     RGKFAVVRKCIEKDSGKEFAAKFMRKRR----KGQDCRMEIIHEIAVLELAQDNPWVINL  56

         79**************************....****************************

S: 69    hevyenksdvililelvaGGelfd..llaekeslseeeatellkqilegvkylhskkivh  126

         hevye+ s++il+le++aGGe+fd  +++++e+++e+++++l++qilegv +lh +++vh

Q: 57    HEVYETPSEMILVLEYAAGGEIFDqcVADREEAFKEKDVQRLMRQILEGVSFLHAHDVVH  116

         ************************988999******************************

S: 127   ldlkPenillldkkvpkgdiklidfGlsrkieegaelkeilGtPefvaPeivnyeplsle  186

         ldlkP+nill++++ p gdik++dfGlsr +++++el+ei+GtPe+vaPei++y+p+s++

Q: 117   LDLKPQNILLTSES-PLGDIKIVDFGLSRIMKNSEELREIMGTPEYVAPEILSYDPISMA  175

         **************.*********************************************

S: 187   tdmwsiGvityillsgasPflGdtkqetllnisavnldfseelfssvselakdfirrllv  246

         tdmwsiGv+ty++l+g+sPflGd+kqet+lnis++nl++see f+ vse+a+dfi++llv

Q: 176   TDMWSIGVLTYVMLTGISPFLGDNKQETFLNISQMNLSYSEEEFDAVSESAVDFIKTLLV  235

         ************************************************************

S: 247   kdpekrltieeclehswl  264

         k+pe+r+t+eecl+h+wl

Q: 236   KKPEDRATAEECLNHPWL  253

         *****************7

Domain Sequence
(FASTA)

RGKFAVVRKC IEKDSGKEFA AKFMRKRRKG QDCRMEIIHE IAVLELAQDN PWVINLHEVY 60

ETPSEMILVL EYAAGGEIFD QCVADREEAF KEKDVQRLMR QILEGVSFLH AHDVVHLDLK 120

PQNILLTSES PLGDIKIVDF GLSRIMKNSE ELREIMGTPE YVAPEILSYD PISMATDMWS 180

IGVLTYVMLT GISPFLGDNK QETFLNISQM NLSYSEEEFD AVSESAVDFI KTLLVKKPED 240

RATAEECLNH PWL 253

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005634	; C:nucleus
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0006917	; P:induction of apoptosis
GO:0007243	; P:intracellular protein kinase cascade
GO:2000377	; P:regulation of reactive oxygen species metabolic process

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013