EPS-EQC-00054

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-EQC-00054

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
DSP/PTEN	259.5	2.4E-77	135	308	174

Status

Unreviewed

Ensembl Protein

ENSECAP00000006709

UniProt Accession

F6UJL0;

Protein Name

Protein Synonyms/Alias

Gene Name

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSECAG00000008376	ENSECAP00000006650	ENSECAT00000008826
ENSECAG00000008376	ENSECAP00000006709	ENSECAT00000008900

Organism

Equus caballus

Functional Description

Protein Length

450

Protein Sequence
(FASTA)

FRIFGILLVF VDMSLIIADQ FISDSKVYIP LEYRSISLAI ALFFLMDVLL RVCVEGMQRY 60

FSDLLNSLDA VIILLTLLID IIYIFYDFSY FNDIPRLAII FRPLRLIILM RVFHLAYQKR 120

HLEILTRRMV SGNKRRYRKD GFDLDLTYIT GRIIAMSFPS SGKHSFYRNP IKEVVRFLDT 180

KHRNHYQVYN LCSERSYNPK HFHHRVHRIM IDDHNVPTLK EMLTLSKEVI EWMAEDKRNI 240

VIHCKGGKGR TGTMVCACLI ACEIFVTAEE SLYYFGERRT DKTSSSKFQG VETPSQNRYV 300

GYFAAVKNIY NMNLPPRRIL MIKKIIVHSI HGVGNGNGRD LKVQIIMRKR IVFVCSASKN 360

CRIHHDVETD RVIITPVNCP PLYDDVKVQF FSSSNIPKYY DKCPFFFWFH TSFMKNRLYL 420

SRSELDNPHK QKTWKIYGPK FAVEIYFKAR 450

Nucleotide Sequence
(FASTA)

TTTAGAATAT TTGGAATCTT GCTCGTCTTT GTGGACATGT CTCTTATCAT CGCAGATCAA 60

TTCATCTCTG ATAGCAAAGT GTATATTCCT TTGGAATATC GTTCAATTTC TTTAGCTATT 120

GCTTTATTTT TTTTAATGGA TGTTCTTCTT CGAGTATGTG TAGAAGGGAT GCAACGATAT 180

TTCTCTGATT TACTTAACTC CTTAGATGCT GTCATTATTC TGCTGACTCT ACTGATTGAT 240

ATAATTTACA TTTTTTATGA CTTCAGTTAT TTTAATGATA TCCCCAGATT GGCAATTATA 300

TTTCGACCTC TACGACTTAT CATTCTGATG AGAGTTTTTC ATCTGGCTTA CCAAAAAAGA 360

CATCTTGAAA TACTGACCAG AAGGATGGTT TCAGGAAACA AACGGCGATA CAGGAAAGAT 420

GGATTTGACT TAGACCTCAC TTACATTACT GGGCGTATTA TTGCGATGTC ATTCCCATCT 480

TCTGGAAAAC ACTCTTTCTA TAGGAATCCC ATTAAGGAAG TTGTGCGGTT CCTGGACACC 540

AAGCATCGAA ACCACTACCA AGTCTACAAT CTATGCAGTG AAAGATCTTA CAATCCTAAG 600

CATTTCCACC ACAGGGTCCA TCGAATCATG ATTGATGATC ACAATGTGCC CACTCTAAAA 660

GAGATGCTGA CTCTTTCGAA GGAAGTCATT GAGTGGATGG CTGAGGATAA AAGAAACATT 720

GTGATTCACT GTAAAGGCGG AAAAGGACGG ACTGGTACTA TGGTTTGTGC CTGCCTGATT 780

GCCTGTGAAA TATTTGTAAC TGCAGAGGAG AGCCTTTATT ATTTTGGAGA ACGACGAACA 840

GATAAAACCA GCAGCTCTAA ATTTCAGGGA GTAGAAACTC CTTCCCAGAA TAGGTATGTT 900

GGATACTTTG CAGCTGTGAA AAATATCTAC AATATGAATC TTCCTCCAAG AAGGATACTT 960

ATGATAAAAA AAATTATTGT TCATTCAATT CATGGTGTTG GAAACGGAAA TGGACGTGAT 1020

CTGAAAGTAC AAATAATAAT GCGCAAAAGG ATTGTCTTTG TCTGTTCTGC TTCCAAGAAC 1080

TGTAGGATAC ATCATGATGT GGAAACAGAT AGAGTGATAA TCACTCCAGT TAATTGTCCA 1140

CCTCTGTATG ATGACGTGAA AGTGCAATTT TTCTCTTCCT CCAATATTCC TAAGTACTAT 1200

GACAAATGCC CGTTTTTCTT CTGGTTTCAT ACATCATTCA TGAAAAACAG GCTTTATCTT 1260

TCAAGAAGCG AACTGGATAA TCCCCATAAA CAGAAGACAT GGAAAATTTA CGGTCCAAAG 1320

TTTGCAGTCG AGATATATTT TAAAGCCAGA 1350

Domain Profile

S: 1     rrltedgfdldltyvteriiavsfPaeareevyrnnlrevvrlldskhrnkyklynlcse  60

         rr+ +dgfdldlty+t riia+sfP+++++++yrn+++evvr+ld khrn+y++ynlcse

Q: 135   RRYRKDGFDLDLTYITGRIIAMSFPSSGKHSFYRNPIKEVVRFLDTKHRNHYQVYNLCSE  194

         79**********************************************************

S: 61    rrydltklnakvaefgiedlnaPaleklvsickeldeWlseddenvvvlhckggkgrlGv  120

         r y++++++ +v++++i+d+n+P+l+++ +++ke+ eW++ed++n+v +hckggkgr+G+

Q: 195   RSYNPKHFHHRVHRIMIDDHNVPTLKEMLTLSKEVIEWMAEDKRNIV-IHCKGGKGRTGT  253

         *********************************************85.9***********

S: 121   ivcayllaseisakadealdtfgerr...tredkvagvkqPsqrryvsyfsqllk  172

         +vca l+a ei+++a+e+l++fgerr   t + k++gv++Psq+ryv yf+ +++

Q: 254   MVCACLIACEIFVTAEESLYYFGERRtdkTSSSKFQGVETPSQNRYVGYFAAVKN  308

         *************************9888899********************987

Domain Sequence
(FASTA)

RRYRKDGFDL DLTYITGRII AMSFPSSGKH SFYRNPIKEV VRFLDTKHRN HYQVYNLCSE 60

RSYNPKHFHH RVHRIMIDDH NVPTLKEMLT LSKEVIEWMA EDKRNIVIHC KGGKGRTGTM 120

VCACLIACEI FVTAEESLYY FGERRTDKTS SSKFQGVETP SQNRYVGYFA AVKN 174

Keyword

Complete proteome; Ion transport; Ionic channel; Membrane; Reference proteome; Transmembrane; Transport.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0016021	; C:integral to membrane
GO:0005216	; F:ion channel activity
GO:0004725	; F:protein tyrosine phosphatase activity
GO:0008138	; F:protein tyrosine/serine/threonine phosphatase activity
GO:0035335	; P:peptidyl-tyrosine dephosphorylation

KEGG

InterPros

IPR008973	; C2_Ca/lipid-bd_dom_CaLB.
IPR000340	; Dual-sp_phosphatase_cat-dom.
IPR005821	; Ion_trans_dom.
IPR014019	; Phosphatase_tensin-typ.
IPR014020	; Tensin_phosphatase_C2-dom.
IPR016130	; Tyr_Pase_AS.

Pfam

PF00782	; DSPc; 1.
PF00520	; Ion_trans; 1.
PF10409	; PTEN_C2; 1.

SMARTs

Prosites

PS51182	; C2_TENSIN; 1.
PS51181	; PPASE_TENSIN; 1.
PS00383	; TYR_PHOSPHATASE_1; 1.

Prints

Created Date

20-Feb-2013