EKS-EQC-00405

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-EQC-00405

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/DAPK	481.9	4.6E-145	13	275	263

Status

Unreviewed

Ensembl Protein

ENSECAP00000010504

UniProt Accession

F6SGZ8;

Protein Name

Protein Synonyms/Alias

Gene Name

DAPK3

Gene Synonyms/Alias

DAPK3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSECAG00000012570	ENSECAP00000010504	ENSECAT00000013252

Organism

Equus caballus

Functional Description

Protein Length

454

Protein Sequence
(FASTA)

MSTFRQEDVE DHYEMGEELG SGQFAIVRKC RQKGTGKEYA AKFIKKRRLS SSRRGVSREE 60

IEREVNILRE IRHPNIITLH DIFENKTDVV LILELVSGGE LFDFLAEKES LTEDEATQFL 120

KQILDGVHYL HSKRIAHFDL KPENIMLLDK NVPNPRIKLI DFGIAHKIEA GNEFKNIFGT 180

PEFVAPEIVN YEPLGLEADM WSIGVITYIL LSGASPFLGE TKQETLTNIS AVNYDFDEEY 240

FSNTSELAKD FIRRLLVKDP KRRMTIAQSL EHSWIKAIRR RNVRREDSGR KPERRRLKTS 300

RLKEYTIKSH SSMPPNNTYV NFERFSKVLE EVAAAEEGLR GLEHSRRLFH EDIEALTAIY 360

EEKEAWYREE NESIGQDLRR LRQELHKTEA LQRQAQEEAK GALLGASGLK RRFSRLENRY 420

EALAKQVASE MRFVQELVRA MEQEKLQGGE CSLR 454

Nucleotide Sequence
(FASTA)

ATGTCCACGT TCAGGCAGGA AGATGTGGAA GACCACTATG AGATGGGGGA GGAGCTGGGC 60

AGCGGCCAGT TTGCGATCGT GCGCAAGTGC CGGCAGAAGG GCACGGGCAA GGAGTACGCG 120

GCCAAGTTCA TCAAGAAGCG CCGCCTGTCG TCCAGCCGGC GGGGGGTGAG CCGGGAGGAG 180

ATCGAGCGGG AGGTGAACAT CCTGCGGGAG ATCCGGCACC CCAACATCAT CACGCTCCAC 240

GACATCTTCG AGAACAAGAC CGACGTCGTG CTCATCCTGG AGCTGGTCTC GGGCGGCGAG 300

CTCTTCGACT TCCTGGCCGA GAAGGAGTCG CTGACGGAGG ACGAGGCCAC CCAGTTCCTC 360

AAGCAGATCC TGGACGGCGT CCACTACCTG CACTCCAAGC GCATCGCCCA CTTCGACCTC 420

AAGCCAGAAA ACATCATGCT CCTGGACAAG AACGTGCCCA ACCCGCGGAT CAAGCTCATC 480

GACTTCGGCA TCGCCCACAA GATCGAGGCG GGGAATGAGT TCAAGAACAT CTTTGGCACC 540

CCGGAGTTTG TGGCGCCCGA GATTGTCAAC TACGAGCCCC TGGGCCTGGA GGCGGACATG 600

TGGAGCATCG GCGTCATCAC CTACATCCTC CTGAGCGGCG CGTCCCCGTT CCTGGGCGAG 660

ACCAAGCAGG AGACGCTGAC CAACATCTCG GCCGTGAACT ATGACTTCGA CGAGGAATAC 720

TTCAGCAACA CCAGCGAGCT GGCCAAGGAC TTCATCCGCC GGCTGCTCGT CAAAGACCCC 780

AAGAGGAGAA TGACCATCGC CCAGAGCCTG GAGCATTCCT GGATCAAGGC GATCCGGCGC 840

CGGAACGTGC GGCGAGAGGA CAGCGGCAGG AAGCCGGAGC GGCGGCGCCT GAAGACGTCC 900

CGCCTCAAGG AGTACACCAT CAAGTCGCAC TCCAGCATGC CCCCCAACAA CACCTACGTC 960

AACTTCGAGC GCTTCTCCAA GGTGCTGGAG GAGGTGGCGG CCGCCGAGGA GGGCCTGCGC 1020

GGGCTCGAGC ACAGCCGGCG CCTGTTCCAC GAGGACATCG AGGCGCTGAC GGCCATCTAC 1080

GAGGAGAAGG AGGCCTGGTA CCGGGAGGAG AACGAGAGCA TCGGCCAGGA CCTGCGGCGG 1140

CTGCGGCAGG AGCTGCACAA GACCGAGGCG CTGCAGCGGC AGGCCCAGGA GGAGGCCAAG 1200

GGCGCGCTGC TGGGGGCCAG CGGGCTCAAG CGCCGCTTCA GCCGCCTGGA GAACCGCTAC 1260

GAGGCCCTGG CCAAGCAGGT GGCCTCCGAG ATGCGCTTCG TGCAGGAGCT GGTGCGCGCC 1320

ATGGAGCAGG AGAAGCTGCA GGGCGGGGAG TGCAGCCTCC GCTAG 1365

Domain Profile

S: 1     letgkelgsGkfavvrkcrekstGkeyaakflkkrrlkssrrgvsreeierevavlkeir  60

         +e+g+elgsG+fa+vrkcr+k tGkeyaakf+kkrrl+ssrrgvsreeierev++l+eir

Q: 13    YEMGEELGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRRGVSREEIEREVNILREIR  72

         5789********************************************************

S: 61    sepnvinlhevyenksdvililelvaGGelfdllaekeslseeeatellkqilegvkylh  120

          +pn+i+lh+++enk+dv+lilelv+GGelfd+laekesl+e+eat++lkqil+gv+ylh

Q: 73    -HPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLH  131

         .***********************************************************

S: 121   skkivhldlkPenillldkkvpkgdiklidfGlsrkieegaelkeilGtPefvaPeivny  180

         sk+i+h+dlkPeni+lldk+vp+++iklidfG+++kie+g+e+k+i+GtPefvaPeivny

Q: 132   SKRIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGNEFKNIFGTPEFVAPEIVNY  191

         ************************************************************

S: 181   eplsletdmwsiGvityillsgasPflGdtkqetllnisavnldfseelfssvselakdf  240

         epl+le+dmwsiGvityillsgasPflG+tkqetl+nisavn+df+ee+fs++selakdf

Q: 192   EPLGLEADMWSIGVITYILLSGASPFLGETKQETLTNISAVNYDFDEEYFSNTSELAKDF  251

         ************************************************************

S: 241   irrllvkdpekrltieeclehswl  264

         irrllvkdp++r+ti+++lehsw+

Q: 252   IRRLLVKDPKRRMTIAQSLEHSWI  275

         ***********************8

Domain Sequence
(FASTA)

YEMGEELGSG QFAIVRKCRQ KGTGKEYAAK FIKKRRLSSS RRGVSREEIE REVNILREIR 60

HPNIITLHDI FENKTDVVLI LELVSGGELF DFLAEKESLT EDEATQFLKQ ILDGVHYLHS 120

KRIAHFDLKP ENIMLLDKNV PNPRIKLIDF GIAHKIEAGN EFKNIFGTPE FVAPEIVNYE 180

PLGLEADMWS IGVITYILLS GASPFLGETK QETLTNISAV NYDFDEEYFS NTSELAKDFI 240

RRLLVKDPKR RMTIAQSLEH SWI 263

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sorex araneus"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0006917	; P:induction of apoptosis
GO:0007243	; P:intracellular protein kinase cascade
GO:0090263	; P:positive regulation of canonical Wnt receptor signaling pathway

KEGG

ecb:100061244

;

InterPros

IPR011009	; Kinase-like_dom.
IPR020675	; Myosin_light_ch_kinase-rel.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013