EKS-EQC-00090

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-EQC-00090

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Atypical/PIKK	444.2	3.5E-133	2138	2462	325

Status

Unreviewed

Ensembl Protein

ENSECAP00000014596

UniProt Accession

F6Z3T6;

Protein Name

Protein Synonyms/Alias

Gene Name

MTOR

Gene Synonyms/Alias

MTOR;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSECAG00000015638	ENSECAP00000014529	ENSECAT00000017852
ENSECAG00000015638	ENSECAP00000014596	ENSECAT00000017925

Organism

Equus caballus

Functional Description

Protein Length

2534

Protein Sequence
(FASTA)

MLGTGPAAAT TATTTSSNVS VLQQFASGLK SRNEETRAKA AKELQHYVTM ELREMSQEES 60

TRFYDQLNHH IFELVSSSDA NERKGGILAI ASLIGVEGGN ATRIGRFANY LRNLLPSNDP 120

VVMEMASKAI GRLAMAGDTF TAEYVEFEVK RALEWLGADR NEGRRHAAVL VLRELAISVP 180

TFFFQQVQPF FDNIFVAVWD PKQAIREGAV AALRACLILT TQREPKEMQK PQWYRHTFEE 240

AEKGFDETLA KEKGMNRDDR IHGALLILNE LVRISSMEGE RLREEMEEIT QQQLVHDKYC 300

KDLMGFGTKP RHITPFTSFQ AVQPQQSNAL VGLLGYSSHQ GLMGFGASPC PAKSTLVESR 360

CCRDLMEEKF DQVCQWVLKC RNSKNSLIQM TILNLLPRLA AFRPSAFTDT QYLQDTMNHV 420

LSCVKKEKER TAAFQALGLL SVAVRSEFKV YLPRVLDIIR AALPPKDFAH KRQKAMQVDA 480

TVFTCISMLA RAMGPGIQQD IKELLEPMLA VGLSPALTAV LYDLSRQIPQ LKKDIQDGLL 540

KMLSLVLMHK PLRHPGMPKG LAHQLASPGL TTLPEASDVG SITLALRTLG SFEFEGHSLT 600

QFVRHCADHF LNSEHKEIRM EAARTCSRLL TPSVHLISGH AHVVSQTAVQ VVADVLSKLL 660

VVGITDPDPD IRYCVLASLD ERFDAHLAQA ENLQALFVAL NDQVFEIREL AICTVGRLSS 720

MNPAFVMPFL RKMLIQILTE LEHSGIGRIK EQSARMLGHL VSNAPRLIRP YMEPILKALI 780

LKLKDPDPDP NPGVINNVLA TIGELAQVSG LEMRKWVDEL FIIIMDMLQD SSLLAKRQVA 840

LWTLGQLVAS TGYVVEPYRK YPTLLEVLLN FLKTEQNQGT RREAIRVLGL LGALDPYKHK 900

VNIGMIDQSR DASAVSLSES KSSQDSSDYS TSEMLVNMGN LPLDEFYPAV SMVALMRIFR 960

DQSLSHHHTM VVQAITFIFK SLGLKCVQFL PQVMPTFLNV IRVCDGAIRE FLFQQLGMLV 1020

SFVKSHIRPY MDEIVTLMRE FWVMNTSIQS TIILLIEQIV VALGGEFKLY LPQLIPHMLR 1080

VFMHDNSPGR IVSIKLLAAI QLFGANLDDY LHLLLPPIVK LFDAPEVPLP SRKAALETVD 1140

RLTESLDFTD YASRIIHPIV RTLDQSPELR PTAMDTLSSL VFQLGKKYQI FIPMVNKVLV 1200

RHRINHQRYD VLICRIVKGY TLADEEEDPL IYQHRMLRSG QGDALASGPV ETGPMKKLHV 1260

STINLQKAEA WGAARRVSKD DWLEWLRRLS LELLKDSSSP SLRSCWALAQ AYNPMARDLF 1320

NAAFVSCWSE LNEDQQDELI RSIELALTSQ DIAEVTQTLL NLAEFMEHSD KGPLPLRDDN 1380

GIVLLGERAA KCRAYAKALH YKELEFQKGP TPAILESLIS INNKLQQPEA AAGVLEYAMK 1440

HFGELEIQAT WYEKLHEWED ALVAYDKKMD TNKDDPELML GRMRCLEALG EWGQLHQQCC 1500

EKWTLVNDET QAKMARMAAA AAWGLGQWDS MEEYTCMIPR DTHDGAFYRA VLALHQDLFS 1560

LAQQCIDKAR DLLDAELTAM AGESYSRAYG AMVSCHMLSE LEEVIQYKLV PERREIIRQI 1620

WWERLQGCQR IVEDWQKILM VRSLVVSPHE DMRTWLKYAS LCGKSGRLAL AHKTLVLLLG 1680

VDPSRQLDHP LPTVHPQVTY AYMKNMWKSA RKIDAFQHMQ HFVQTMQQQA QHAIATEDQQ 1740

HKQELHKLMA RCFLKLGEWQ LNLQGINEST IPKVLQYYSA ATEHDRSWYK AWHAWAVMNF 1800

EAVLHYKHQN QARDEKKKLP TATATATSTE GSNSESEAES TENSPTPSPL QKKVTEDLSK 1860

TLLMYTVPAV QGFFRSISLS RGNNLQDTLR VLTLWFDYGH WPDVNEALVE GVKAIQIDTW 1920

LQVIPQLIAR IDTPRPLVGR LIHQLLTDIG RYHPQALIYP LTVASKSTTT ARHNAANKIL 1980

KNMCEHSNTL VQQAMMVSEE LIRVAILWHE MWHEGLEEAS RLYFGERNVK GMFEVLEPLH 2040

AMMERGPQTL KETSFNQAYG RDLMEAQEWC RKYMKSGNVK DLTQAWDLYY HVFRRISKQL 2100

PQLTSLELQY VSPKLLMCRD LELAVPGTYD PNQPIIRIQS IAPSLQVITS KQRPRKLTLM 2160

GSNGHEFVFL LKGHEDLRQD ERVMQLFGLV NTLLANDPTS LRKNLSIQRY AVIPLSTNSG 2220

LIGWVPHCDT LHALIRDYRE KKKILLNIEH RIMLRMAPDY DHLTLMQKVE VFEHAVNNTA 2280

GDDLAKLLWL KSPSSEVWFD RRTNYTRSLA VMSMVGYILG LGDRHPSNLM LDRLSGKILH 2340

IDFGDCFEVA MTREKFPEKI PFRLTRMLTN AMEVTGLDGN YRITCHTVME VLREHKDSVM 2400

AVLEAFVYDP LLNWRLMDTN TKGNKRSRTR TDSYSAGQSV EILDGVELGE PAHKKTGTTV 2460

PESIHSFIGD GLVKPEALNK KAIQIINRVR DKLTGRDFSH DETLDVPTQV ELLIKQATSH 2520

ENLCQCYIGW CPFW 2534

Nucleotide Sequence
(FASTA)

ATGCTTGGGA CCGGACCTGC CGCCGCCACC ACAGCTACCA CCACATCCAG CAATGTGAGC 60

GTTCTGCAGC AGTTTGCCAG TGGTCTGAAG AGCCGGAATG AGGAGACCAG AGCAAAAGCT 120

GCCAAGGAGC TCCAGCACTA TGTCACCATG GAGCTTCGAG AGATGAGTCA AGAGGAGTCA 180

ACTCGCTTCT ATGATCAACT GAACCATCAC ATTTTTGAAC TGGTTTCCAG CTCAGATGCC 240

AATGAGAGGA AAGGTGGCAT CTTGGCCATA GCCAGCCTCA TAGGAGTGGA AGGCGGCAAT 300

GCCACCCGGA TCGGCAGATT TGCTAACTAT CTTCGGAACC TCCTTCCCTC TAATGACCCA 360

GTTGTCATGG AAATGGCCTC CAAGGCTATT GGCCGCCTTG CCATGGCAGG GGACACTTTC 420

ACTGCTGAGT ACGTGGAGTT TGAGGTGAAG CGAGCCCTGG AATGGCTGGG TGCTGACCGC 480

AACGAGGGCC GGAGACATGC AGCTGTTCTG GTTCTCCGTG AGCTGGCCAT CAGCGTCCCC 540

ACCTTCTTCT TCCAGCAAGT GCAACCCTTC TTTGACAACA TTTTTGTGGC TGTATGGGAT 600

CCCAAACAGG CCATCCGTGA GGGAGCTGTA GCTGCCCTTC GTGCCTGTCT GATTCTCACC 660

ACCCAGCGTG AGCCAAAGGA GATGCAGAAG CCCCAGTGGT ACAGGCACAC ATTCGAAGAA 720

GCGGAGAAAG GGTTTGACGA GACCTTGGCC AAGGAGAAGG GCATGAATCG GGATGATCGG 780

ATCCATGGAG CCTTGCTGAT CCTCAATGAG CTGGTCCGAA TCAGCAGCAT GGAGGGAGAG 840

CGCCTGAGAG AAGAAATGGA AGAAATCACA CAGCAGCAAT TGGTCCATGA CAAGTACTGC 900

AAAGATCTCA TGGGCTTCGG AACAAAACCT CGCCACATTA CCCCCTTTAC CAGTTTCCAG 960

GCTGTGCAGC CCCAGCAGTC AAATGCCTTG GTAGGACTGC TGGGATACAG CTCTCACCAA 1020

GGCCTCATGG GATTTGGGGC TTCCCCCTGC CCAGCTAAGT CCACCCTGGT GGAGAGCCGG 1080

TGTTGCAGAG ACTTGATGGA GGAGAAATTT GATCAGGTGT GCCAGTGGGT GCTGAAATGC 1140

AGGAATAGCA AGAACTCGCT GATCCAAATG ACAATCCTTA ATTTGTTGCC CCGCTTGGCT 1200

GCATTTCGGC CTTCTGCCTT CACAGATACC CAGTACCTCC AAGATACCAT GAACCATGTC 1260

CTAAGCTGTG TCAAGAAGGA GAAGGAACGT ACAGCAGCCT TCCAAGCCCT GGGGCTACTT 1320

TCTGTGGCTG TGAGGTCTGA GTTTAAGGTC TATTTACCTC GTGTGCTGGA CATCATTCGA 1380

GCAGCCTTGC CCCCTAAGGA CTTTGCCCAT AAGAGACAGA AGGCAATGCA GGTGGACGCC 1440

ACAGTGTTCA CTTGCATCAG CATGTTAGCT CGAGCAATGG GTCCAGGCAT CCAGCAGGAT 1500

ATCAAGGAGC TGCTAGAGCC CATGCTGGCA GTGGGACTGA GCCCTGCCCT CACAGCTGTG 1560

CTCTATGACC TGAGCCGTCA GATTCCACAG CTGAAGAAGG ACATCCAAGA TGGGCTACTG 1620

AAGATGCTGT CCCTGGTCCT TATGCACAAA CCCCTCCGGC ACCCAGGAAT GCCCAAGGGC 1680

CTAGCCCATC AGCTGGCTTC CCCTGGCCTC ACAACCCTCC CTGAGGCCAG CGATGTGGGC 1740

AGCATCACTC TTGCCCTCCG AACTCTTGGC AGCTTTGAAT TTGAAGGCCA CTCTCTGACC 1800

CAGTTTGTCC GCCACTGTGC GGATCATTTC CTGAACAGCG AGCACAAGGA GATCCGCATG 1860

GAAGCCGCCC GCACCTGCTC CCGCCTGCTC ACGCCCTCTG TCCACCTCAT CAGCGGCCAC 1920

GCTCATGTGG TTAGCCAGAC TGCAGTGCAA GTGGTAGCAG ATGTACTCAG CAAACTGCTC 1980

GTGGTTGGGA TAACAGATCC TGACCCTGAC ATCCGCTACT GTGTCTTGGC ATCCCTGGAT 2040

GAGCGCTTTG ATGCACACCT GGCCCAGGCA GAGAATTTGC AGGCCCTCTT TGTGGCCCTG 2100

AATGACCAAG TGTTTGAGAT CCGGGAGCTG GCCATCTGCA CTGTGGGCCG GCTCAGTAGC 2160

ATGAACCCAG CTTTCGTCAT GCCTTTCCTA CGCAAGATGC TCATCCAGAT TTTGACAGAG 2220

CTGGAGCACA GTGGCATTGG AAGAATCAAA GAGCAGAGTG CCCGCATGCT GGGGCACCTT 2280

GTCTCCAACG CTCCCCGGCT CATCCGCCCC TACATGGAGC CTATTCTGAA GGCTTTAATT 2340

TTGAAACTGA AAGATCCAGA CCCTGATCCA AACCCAGGTG TGATCAATAA TGTCTTGGCT 2400

ACAATAGGAG AATTGGCTCA GGTTAGTGGC TTAGAAATGA GAAAATGGGT TGATGAACTG 2460

TTTATCATCA TCATGGACAT GCTCCAGGAC TCTTCTCTTT TGGCCAAAAG GCAGGTGGCT 2520

CTCTGGACCC TGGGACAGTT GGTGGCCAGC ACTGGTTATG TGGTGGAGCC CTACAGGAAG 2580

TACCCCACTT TGCTTGAGGT GCTGCTGAAT TTTCTGAAGA CTGAGCAGAA CCAGGGTACC 2640

CGGAGAGAGG CTATCCGTGT GTTAGGGCTT CTGGGGGCCT TGGATCCCTA CAAGCACAAA 2700

GTGAACATCG GCATGATCGA CCAGTCCCGT GATGCTTCTG CTGTCAGCCT GTCAGAATCC 2760

AAGTCAAGTC AGGATTCCTC TGACTACAGC ACCAGTGAAA TGCTGGTCAA CATGGGGAAC 2820

CTGCCTCTGG ACGAGTTCTA CCCAGCTGTG TCCATGGTGG CCCTGATGCG GATCTTCCGA 2880

GACCAGTCCC TCTCTCACCA TCACACCATG GTTGTCCAGG CCATCACCTT CATCTTCAAG 2940

TCCCTGGGGC TCAAGTGTGT GCAGTTCCTG CCCCAGGTCA TGCCCACGTT CCTGAATGTC 3000

ATTCGGGTCT GTGACGGGGC CATCCGGGAA TTTCTGTTCC AGCAGTTGGG AATGTTGGTG 3060

TCCTTTGTGA AGAGCCACAT CAGACCTTAT ATGGATGAAA TAGTCACCCT CATGAGAGAA 3120

TTCTGGGTCA TGAACACCTC AATCCAGAGC ACAATCATTC TTCTCATTGA GCAAATTGTG 3180

GTAGCTCTTG GGGGTGAATT TAAGCTGTAC CTGCCCCAGC TGATCCCGCA CATGCTACGT 3240

GTCTTCATGC ATGACAACAG CCCAGGCCGC ATTGTCTCCA TCAAGTTGCT GGCTGCAATC 3300

CAGCTGTTTG GTGCCAACCT GGATGACTAT CTGCACTTGT TGTTGCCTCC GATTGTGAAG 3360

TTGTTTGATG CCCCTGAAGT TCCACTGCCA TCTCGAAAGG CAGCATTAGA GACGGTGGAC 3420

CGCCTAACAG AGTCCCTGGA TTTCACTGAC TATGCCTCCC GGATCATTCA CCCAATTGTT 3480

CGAACACTGG ACCAGAGCCC AGAACTGCGT CCCACAGCCA TGGACACCTT GTCTTCACTT 3540

GTCTTTCAGC TGGGGAAGAA GTATCAAATT TTCATTCCAA TGGTGAATAA AGTCCTGGTG 3600

CGACACCGAA TCAACCATCA GCGCTATGAT GTGCTTATCT GCAGAATTGT CAAGGGATAC 3660

ACCCTTGCTG ATGAAGAAGA GGACCCTTTG ATTTACCAGC ATCGAATGCT GAGGAGTGGC 3720

CAAGGGGATG CATTGGCTAG TGGACCAGTA GAAACGGGGC CCATGAAGAA ACTGCATGTC 3780

AGCACCATCA ACCTCCAAAA GGCAGAAGCC TGGGGAGCTG CCAGAAGGGT CTCCAAAGAT 3840

GACTGGCTGG AATGGCTGCG GCGGCTGAGT CTGGAGCTGC TGAAGGACTC CTCATCACCC 3900

TCCCTGCGCT CCTGCTGGGC CCTGGCTCAG GCCTACAACC CAATGGCCAG GGATCTCTTC 3960

AATGCTGCAT TTGTGTCCTG CTGGTCTGAA CTGAATGAAG ACCAGCAGGA TGAACTCATT 4020

AGAAGCATCG AGTTGGCCCT CACTTCACAG GACATTGCTG AAGTCACACA AACGCTCTTA 4080

AACTTGGCTG AATTCATGGA ACACAGTGAC AAGGGCCCCC TGCCATTGAG AGACGACAAT 4140

GGCATCGTCC TGCTGGGTGA GAGGGCTGCC AAGTGCCGAG CATATGCCAA AGCACTACAC 4200

TACAAAGAAC TGGAGTTCCA GAAAGGTCCA ACCCCCGCCA TCCTAGAATC TCTCATCAGC 4260

ATTAATAATA AGCTACAGCA ACCAGAGGCA GCTGCCGGGG TGTTAGAATA CGCCATGAAA 4320

CACTTTGGAG AGCTGGAGAT TCAGGCTACC TGGTATGAGA AACTGCATGA GTGGGAGGAT 4380

GCTCTTGTAG CATATGATAA GAAAATGGAC ACCAACAAGG ATGACCCAGA GCTGATGCTG 4440

GGCCGCATGC GCTGCCTCGA GGCCTTGGGG GAATGGGGGC AGCTCCACCA GCAGTGCTGT 4500

GAAAAGTGGA CCCTGGTTAA TGATGAGACC CAAGCCAAGA TGGCCCGGAT GGCTGCTGCA 4560

GCCGCGTGGG GCTTAGGTCA GTGGGACAGC ATGGAAGAGT ACACCTGTAT GATCCCTCGG 4620

GACACCCACG ATGGGGCATT TTATAGGGCT GTGCTGGCAC TACATCAGGA CCTCTTCTCC 4680

TTGGCACAAC AGTGCATCGA CAAAGCCAGA GACCTGCTGG ATGCTGAGTT AACCGCTATG 4740

GCAGGAGAGA GCTACAGTCG GGCATATGGG GCCATGGTTT CTTGCCACAT GCTCTCTGAG 4800

CTGGAGGAGG TTATCCAGTA CAAACTTGTC CCCGAGCGAC GAGAGATCAT CCGCCAGATC 4860

TGGTGGGAGA GACTGCAGGG CTGCCAGCGT ATTGTGGAGG ACTGGCAGAA AATCCTTATG 4920

GTGCGCTCCC TTGTGGTCAG CCCTCATGAG GACATGAGGA CCTGGCTCAA GTATGCAAGC 4980

CTATGTGGCA AGAGTGGCAG GCTGGCTCTT GCTCATAAAA CCTTAGTGTT GCTCCTGGGA 5040

GTTGATCCAT CTCGGCAACT TGACCATCCT CTGCCAACAG TTCATCCTCA GGTGACCTAC 5100

GCCTACATGA AAAACATGTG GAAGAGTGCT CGCAAGATCG ATGCCTTCCA GCACATGCAG 5160

CACTTTGTTC AGACCATGCA GCAGCAGGCC CAGCACGCCA TTGCTACTGA GGACCAGCAG 5220

CACAAGCAAG AGCTGCACAA GCTCATGGCC CGGTGTTTCC TGAAACTCGG GGAGTGGCAG 5280

CTGAACCTAC AGGGCATCAA CGAGAGCACC ATCCCCAAAG TCCTGCAGTA CTACAGCGCC 5340

GCCACGGAGC ACGACCGCAG CTGGTACAAG GCCTGGCATG CATGGGCAGT GATGAACTTC 5400

GAAGCTGTGC TACACTACAA ACATCAGAAC CAAGCCCGTG ATGAGAAGAA GAAGCTGCCC 5460

ACTGCCACCG CCACTGCCAC CAGCACTGAG GGCAGCAACA GTGAGAGCGA GGCCGAGAGC 5520

ACCGAGAACA GCCCTACCCC ATCTCCTCTG CAGAAGAAGG TCACTGAGGA TTTGTCCAAA 5580

ACCCTCTTGA TGTACACTGT CCCTGCTGTC CAGGGCTTCT TCCGTTCTAT CTCGCTGTCA 5640

CGAGGCAACA ACCTCCAGGA TACGCTCAGA GTCCTCACCT TATGGTTTGA TTATGGCCAC 5700

TGGCCAGATG TAAATGAAGC CTTAGTGGAA GGGGTGAAAG CGATCCAGAT TGACACTTGG 5760

TTACAGGTTA TACCTCAGCT CATTGCAAGA ATTGATACAC CCAGGCCCTT GGTGGGACGT 5820

CTCATTCACC AGCTTCTCAC AGACATTGGT CGGTACCACC CCCAGGCCCT CATCTACCCC 5880

TTGACTGTGG CTTCTAAGTC CACCACCACA GCCCGTCACA ACGCAGCCAA CAAGATTCTG 5940

AAGAACATGT GTGAGCACAG TAACACCCTG GTCCAGCAGG CCATGATGGT GAGTGAGGAG 6000

CTGATCCGAG TGGCCATCCT CTGGCATGAG ATGTGGCATG AAGGCCTGGA GGAAGCGTCG 6060

CGTTTGTACT TTGGGGAGAG GAATGTGAAA GGCATGTTTG AGGTGCTGGA GCCCCTGCAT 6120

GCTATGATGG AACGGGGACC CCAGACTCTG AAGGAAACAT CCTTTAACCA GGCGTATGGT 6180

CGAGATTTAA TGGAGGCCCA AGAGTGGTGC AGGAAGTATA TGAAATCAGG GAATGTCAAG 6240

GATCTCACTC AAGCCTGGGA CCTCTATTAT CATGTGTTCA GACGAATCTC AAAGCAGCTG 6300

CCTCAGCTCA CATCCTTAGA GCTGCAATAT GTTTCCCCAA AACTTCTGAT GTGCCGGGAC 6360

CTCGAATTGG CTGTGCCAGG AACCTATGAC CCCAACCAGC CGATCATTCG CATTCAGTCC 6420

ATAGCACCGT CTTTGCAAGT CATCACATCC AAGCAGAGGC CCCGGAAGTT GACACTTATG 6480

GGCAGCAACG GGCATGAGTT TGTTTTCCTC CTGAAGGGCC ATGAAGATCT ACGACAGGAC 6540

GAACGAGTGA TGCAGCTCTT TGGCCTGGTT AACACTCTTT TGGCCAATGA CCCAACATCT 6600

CTTCGGAAAA ACCTCAGCAT CCAGAGATAT GCTGTCATCC CGTTATCAAC TAACTCGGGC 6660

CTCATCGGCT GGGTCCCCCA CTGTGACACT CTGCATGCTC TCATCCGGGA CTACAGGGAG 6720

AAAAAGAAGA TCCTTCTCAA CATTGAGCAT CGCATCATGT TGCGGATGGC TCCGGACTAC 6780

GATCACCTGA CCCTGATGCA GAAGGTCGAG GTGTTTGAGC ATGCTGTCAA TAACACAGCC 6840

GGGGACGACC TGGCCAAGCT GCTGTGGCTG AAAAGCCCCA GCTCCGAGGT GTGGTTTGAC 6900

CGAAGAACCA ATTATACCCG CTCCTTAGCA GTCATGTCCA TGGTTGGGTA TATTTTGGGC 6960

CTGGGAGATA GACACCCATC CAACCTAATG CTGGACCGGC TGAGTGGGAA GATCCTGCAC 7020

ATTGACTTTG GGGACTGCTT TGAGGTTGCT ATGACCAGAG AGAAATTCCC AGAGAAGATT 7080

CCTTTTAGAC TAACAAGAAT GTTGACCAAT GCTATGGAGG TTACCGGTCT GGATGGCAAC 7140

TACAGAATCA CGTGCCACAC AGTGATGGAA GTGCTTCGGG AACACAAGGA CAGTGTCATG 7200

GCCGTGCTGG AAGCCTTTGT CTATGACCCC TTGCTGAACT GGAGGCTGAT GGACACAAAT 7260

ACCAAAGGCA ACAAGCGGTC CCGAACGAGG ACAGATTCCT ACTCTGCTGG CCAGTCAGTA 7320

GAAATTTTGG ATGGTGTGGA ACTTGGGGAA CCAGCCCATA AGAAAACGGG GACCACAGTG 7380

CCAGAATCTA TTCATTCTTT CATTGGAGAC GGTTTGGTGA AACCAGAGGC CCTAAATAAG 7440

AAAGCTATTC AAATTATTAA CAGGGTTCGA GATAAACTCA CTGGTCGGGA CTTCTCTCAT 7500

GATGAAACTT TGGATGTCCC AACACAAGTT GAGCTGCTCA TCAAACAAGC AACATCCCAT 7560

GAAAACCTCT GCCAGTGCTA CATCGGCTGG TGTCCTTTCT GGTAA 7605

Domain Profile

S: 1     iagfderveilaskqkpkklllrGsdgkeypyLvkgkeDlrqdervlqlfslvNtlLakd  60

         i+++++++++++skq+p+kl+l+Gs+g+e+++L+kg+eDlrqderv+qlf+lvNtlLa+d

Q: 2138  IQSIAPSLQVITSKQRPRKLTLMGSNGHEFVFLLKGHEDLRQDERVMQLFGLVNTLLAND  2197

         899*********************************************************

S: 61    ketsrrkLkirtykVvplstrsgliewventvsLkellkklvekkavlldqpisyrykdl  120

         +++ r++L+i++y+V+plst+sgli+wv+++++L++l+++++ekk++ll+        ++

Q: 2198  PTSLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKKILLN-------IEH  2250

         *************************************************9.......9**

S: 121   stvqarkpklkhlkls..levfkevlenlvpkdllkklllekfpspeewfelrkaytrsl  178

         +++ +++p+++hl+l+  +evf+++++n ++ d l+kll+ k+ps+e+wf++r++ytrsl

Q: 2251  RIMLRMAPDYDHLTLMqkVEVFEHAVNN-TAGDDLAKLLWLKSPSSEVWFDRRTNYTRSL  2309

         ****************************.999****************************

S: 179   AvislvgyiLgLgdrhlenllidqetgevvhidfgvafekaktqlkvpekvPFRLTrniv  238

         Av+s+vgyiLgLgdrh++nl++d+ +g+++hidfg +fe a+t++k+pek+PFRLTr+++

Q: 2310  AVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLT  2369

         ************************************************************

S: 239   nalgvtgveGvfrasceavlrvlreskeklltiLevflydplvdwkkkkktsketeeela  298

         na++vtg++G++r++c++v++vlre+k++++++Le+f+ydpl++w+ +++++k+++++++

Q: 2370  NAMEVTGLDGNYRITCHTVMEVLREHKDSVMAVLEAFVYDPLLNWRLMDTNTKGNKRSRT  2429

         ************************************************************

S: 299   ekakaealkikkllskvekaenavatrdlllle  331

         ++++++a +++++l++ve +e+a+++++++++e

Q: 2430  RTDSYSAGQSVEILDGVELGEPAHKKTGTTVPE  2462

         ****************************99987

Domain Sequence
(FASTA)

IQSIAPSLQV ITSKQRPRKL TLMGSNGHEF VFLLKGHEDL RQDERVMQLF GLVNTLLAND 60

PTSLRKNLSI QRYAVIPLST NSGLIGWVPH CDTLHALIRD YREKKKILLN IEHRIMLRMA 120

PDYDHLTLMQ KVEVFEHAVN NTAGDDLAKL LWLKSPSSEV WFDRRTNYTR SLAVMSMVGY 180

ILGLGDRHPS NLMLDRLSGK ILHIDFGDCF EVAMTREKFP EKIPFRLTRM LTNAMEVTGL 240

DGNYRITCHT VMEVLREHKD SVMAVLEAFV YDPLLNWRLM DTNTKGNKRS RTRTDSYSAG 300

QSVEILDGVE LGEPAHKKTG TTVPE 325

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005829	; C:cytosol
GO:0012505	; C:endomembrane system
GO:0005764	; C:lysosome
GO:0016020	; C:membrane
GO:0016605	; C:PML body
GO:0005524	; F:ATP binding
GO:0008144	; F:drug binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0043022	; F:ribosome binding
GO:0001030	; F:RNA polymerase III type 1 promoter DNA binding
GO:0001031	; F:RNA polymerase III type 2 promoter DNA binding
GO:0001032	; F:RNA polymerase III type 3 promoter DNA binding
GO:0071456	; P:cellular response to hypoxia
GO:0031669	; P:cellular response to nutrient levels
GO:0007281	; P:germ cell development
GO:0045792	; P:negative regulation of cell size
GO:0016242	; P:negative regulation of macroautophagy
GO:0051534	; P:negative regulation of NFAT protein import into nucleus
GO:0018105	; P:peptidyl-serine phosphorylation
GO:0018107	; P:peptidyl-threonine phosphorylation
GO:0030838	; P:positive regulation of actin filament polymerization
GO:0010592	; P:positive regulation of lamellipodium assembly
GO:0046889	; P:positive regulation of lipid biosynthetic process
GO:0050731	; P:positive regulation of peptidyl-tyrosine phosphorylation
GO:0051496	; P:positive regulation of stress fiber assembly
GO:0045945	; P:positive regulation of transcription from RNA polymerase III promoter
GO:0045859	; P:regulation of protein kinase activity
GO:0032314	; P:regulation of Rac GTPase activity
GO:0043200	; P:response to amino acid stimulus
GO:0032868	; P:response to insulin stimulus
GO:0031529	; P:ruffle organization
GO:0031929	; P:TOR signaling cascade

KEGG

InterPros

IPR011989	; ARM-like.
IPR016024	; ARM-type_fold.
IPR024585	; DUF3385_TOR.
IPR003152	; FATC.
IPR011009	; Kinase-like_dom.
IPR000403	; PI3/4_kinase_cat_dom.
IPR018936	; PI3/4_kinase_CS.
IPR003151	; PIK-rel_kinase_FAT.
IPR014009	; PIK_FAT.
IPR009076	; Rapamycin-bd_dom.
IPR026683	; TOR/Smg1.

Pfam

PF11865	; DUF3385; 1.
PF02259	; FAT; 1.
PF02260	; FATC; 1.
PF00454	; PI3_PI4_kinase; 1.
PF08771	; Rapamycin_bind; 1.

SMARTs

SM00146

; PI3Kc; 1.

Prosites

PS51189	; FAT; 1.
PS51190	; FATC; 1.
PS00915	; PI3_4_KINASE_1; 1.
PS00916	; PI3_4_KINASE_2; 1.
PS50290	; PI3_4_KINASE_3; 1.

Prints

Created Date

20-Feb-2013