EKS-EQC-00469

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-EQC-00469

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMK1	372.9	8.9E-112	46	299	254

Status

Unreviewed

Ensembl Protein

ENSECAP00000014287

UniProt Accession

F6WUG4;

Protein Name

Protein Synonyms/Alias

Gene Name

CAMK4

Gene Synonyms/Alias

CAMK4;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSECAG00000016696	ENSECAP00000014287	ENSECAT00000017572

Organism

Equus caballus

Functional Description

Protein Length

472

Protein Sequence
(FASTA)

MLKVTVPSCS ASSCSSVTAS VAPATGSLVP DYWIDGSNRD ALNDFFEVES ELGRGATSIV 60

YRCKQKGTQK PYALKVLKKT VDKKIVRTEI GVLLRLSHPN IIKLKEIFET PTEISLVLEL 120

VTGGELFDRI VEKGYYSERD AADAVKQILE AVAYLHENGI VHRDLKPENL LYATPAPDAP 180

LKIADFGLSK IVEHQVLMKT VCGTPGYCAP EILRGCAYGP EVDMWSVGII TYILLCGFEP 240

FYDERGDQFM FRRILNCEYY FIPWWDEVSL NAKDLVRKLI ILDPKKRLTT FQALQHPWVT 300

GKAANFVHMD TAQKKLQEFN ARRKLKAAVK AVVASSRLGS ASSSHGSVQE SQKSSREPSP 360

IQDSNEDVKA IPEGVKVQGD GAQMAVEGAE AELMKAQAVE KVKDADINAA QAAKMVSKAL 420

EHGIRVADPE IEEGLVREKL KTVEEAAAPR EGQENPALGF GAQQNDVILP EY 472

Nucleotide Sequence
(FASTA)

ATGCTCAAAG TCACGGTGCC CTCGTGCTCC GCCTCGTCCT GCTCTTCGGT CACCGCCAGC 60

GTGGCCCCGG CTACCGGGAG CCTCGTCCCG GATTATTGGA TCGACGGCTC CAACAGGGAT 120

GCTTTGAACG ATTTCTTCGA GGTGGAGTCG GAGCTTGGTC GGGGTGCTAC ATCCATTGTG 180

TACAGATGCA AACAGAAGGG GACCCAGAAG CCTTATGCTC TCAAAGTGTT AAAGAAAACA 240

GTGGACAAAA AAATCGTAAG AACTGAGATA GGAGTTCTTC TTCGCCTCTC ACATCCAAAC 300

ATTATAAAAC TTAAAGAGAT ATTTGAAACT CCTACAGAAA TCAGTCTGGT CCTAGAACTC 360

GTCACAGGAG GAGAGCTGTT CGACAGGATT GTGGAAAAAG GATATTATAG TGAACGAGAT 420

GCTGCAGATG CTGTTAAACA AATCCTGGAG GCAGTCGCTT ACTTACATGA AAATGGGATT 480

GTCCATCGTG ATCTCAAACC AGAGAATCTT CTCTATGCAA CTCCAGCCCC AGATGCACCA 540

CTCAAAATCG CTGATTTTGG ACTTTCTAAA ATTGTGGAAC ATCAAGTGCT CATGAAGACA 600

GTATGTGGAA CCCCAGGGTA CTGCGCTCCT GAGATTCTTC GAGGCTGTGC CTATGGGCCT 660

GAGGTGGACA TGTGGTCTGT AGGAATAATC ACCTATATCC TACTTTGTGG ATTTGAACCA 720

TTCTATGATG AAAGAGGCGA TCAATTCATG TTCAGGAGAA TTCTGAATTG TGAATATTAC 780

TTTATCCCCT GGTGGGATGA AGTATCTCTA AATGCCAAGG ACTTGGTCAG AAAATTAATT 840

ATTTTGGATC CTAAGAAACG GCTGACTACC TTCCAAGCTC TCCAGCACCC ATGGGTCACA 900

GGTAAAGCAG CCAATTTTGT ACACATGGAT ACTGCTCAAA AGAAGCTCCA AGAATTCAAT 960

GCCCGGCGCA AGCTTAAGGC AGCAGTGAAG GCCGTGGTGG CCTCTTCCCG CTTGGGAAGC 1020

GCCAGCAGCA GCCATGGCAG CGTCCAGGAG AGCCAGAAGT CCAGCCGAGA GCCATCTCCA 1080

ATCCAGGACA GCAATGAAGA TGTTAAAGCT ATTCCAGAAG GAGTGAAAGT TCAAGGAGAT 1140

GGGGCCCAAA TGGCAGTTGA GGGGGCAGAG GCTGAGCTGA TGAAGGCACA GGCTGTAGAG 1200

AAGGTTAAAG ATGCTGATAT AAATGCTGCC CAGGCCGCCA AAATGGTGTC CAAGGCACTA 1260

GAGCATGGGA TAAGGGTGGC TGACCCAGAA ATAGAGGAGG GCTTAGTGAG GGAGAAGCTG 1320

AAGACTGTGG AGGAAGCAGC AGCCCCCAGA GAAGGGCAAG AAAACCCTGC TCTGGGATTT 1380

GGAGCTCAGC AGAATGATGT GATCCTGCCA GAGTACTAA 1419

Domain Profile

S: 1     yklkeklGeGafsevlkakekktqkavaikvikkkalkgkeesveneiavlkklkhpniv  60

         ++++++lG+Ga+s v+++k+k tqk++a+kv+kk+    +++ v++ei vl +l+hpni+

Q: 46    FEVESELGRGATSIVYRCKQKGTQKPYALKVLKKTV---DKKIVRTEIGVLLRLSHPNII  102

         7899******************************98...89*******************

S: 61    alkdiyesksklylvlelvtGGelfdrivekgvytekdasevikqvleavkylhelgivh  120

         +lk+i+e++++++lvlelvtGGelfdrivekg+y+e+da++ +kq+leav+ylhe+givh

Q: 103   KLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHENGIVH  162

         ************************************************************

S: 121   rdlkPenllylskeedskikiadfGlskleeke.llktacGtvgyvapevlkqkkyskkv  179

         rdlkPenlly++++ d+++kiadfGlsk+ e++ l+kt+cGt+gy+ape+l+ ++y+ +v

Q: 163   RDLKPENLLYATPAPDAPLKIADFGLSKIVEHQvLMKTVCGTPGYCAPEILRGCAYGPEV  222

         ****************************9999989*************************

S: 180   dvWsiGvityillcGyppfydekeekl.lekilkgeyefesPyWdeisesakdfikklle  238

         d+Ws+G+ityillcG++pfyde+ +++ +++il++ey+f  P+Wde+s +akd+++kl+

Q: 223   DMWSVGIITYILLCGFEPFYDERGDQFmFRRILNCEYYFI-PWWDEVSLNAKDLVRKLII  281

         ***********************9998789*******995.*******************

S: 239   ldpekrytieqaledpWi  256

         ldp+kr+t+ qal++pW+

Q: 282   LDPKKRLTTFQALQHPWV  299

         *****************7

Domain Sequence
(FASTA)

FEVESELGRG ATSIVYRCKQ KGTQKPYALK VLKKTVDKKI VRTEIGVLLR LSHPNIIKLK 60

EIFETPTEIS LVLELVTGGE LFDRIVEKGY YSERDAADAV KQILEAVAYL HENGIVHRDL 120

KPENLLYATP APDAPLKIAD FGLSKIVEHQ VLMKTVCGTP GYCAPEILRG CAYGPEVDMW 180

SVGIITYILL CGFEPFYDER GDQFMFRRIL NCEYYFIPWW DEVSLNAKDL VRKLIILDPK 240

KRLTTFQALQ HPWV 254

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005737	; C:cytoplasm
GO:0005634	; C:nucleus
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0007616	; P:long-term memory
GO:0043011	; P:myeloid dendritic cell differentiation
GO:0007270	; P:neuron-neuron synaptic transmission
GO:0006913	; P:nucleocytoplasmic transport
GO:0046827	; P:positive regulation of protein export from nucleus
GO:0045893	; P:positive regulation of transcription, DNA-dependent
GO:0007165	; P:signal transduction

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013