EKS-EQC-00202

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-EQC-00202

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDKL	484.0	1.2E-145	4	286	283

Status

Unreviewed

Ensembl Protein

ENSECAP00000015775

UniProt Accession

F6Q3Y7;

Protein Name

Protein Synonyms/Alias

Gene Name

CDKL3

Gene Synonyms/Alias

CDKL3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSECAG00000018013	ENSECAP00000015775	ENSECAT00000019284

Organism

Equus caballus

Functional Description

Protein Length

589

Protein Sequence
(FASTA)

MEMYESLGKV GEGSYGTVMK CKHKETGQIV AIKIFYEKPE KSVNKIATRE IKFLKQFRHE 60

NLVNLIEVFR QKKKIHLVFE FIDHTVLDEL QHYCHGLESK RLRKYLFQIL RAIEYLHDNN 120

IIHRDIKPEN ILVSQSGITK LCDFGFARTL AAPGDIYTDY VATRWYRAPE LVLKDTSYGK 180

PVDIWALGCM IIEMATGNPY LPSSSDLDLL HKIVLKVGNL TPHLQNIFSN NPIFAGVVLP 240

QVQHPKNARK KYPKLNGLLA DIVHACLQID PAERISSTEL LHHEYFTRDG FVEKFIPELR 300

AKLLQEAKVN SFIKPKENSK ANELMKNERK TIYTNTLLST SVLGKEMEKE KKPKEIKVRV 360

IKVKGGKGDI LESKKMECEG RHCQQEATEN AHTMSQDANP IINESPNPVN PSTNSNGMKD 420

SPHAGGSMMM PPINLTSSNL MALNTNSKLS HSNSRSTERA KKRRTSLQSI GQVVSNSRQE 480

DTGSTQSQME KGVFNEQMGQ SDQMANRNKR KLNFSRSDRK EFHFPELPFT IHSKEMKRME 540

VKQIKVLKRE SKKTDSSKIP TLLNVDQNQE KQESGDGYCE GKSLKRNRF 589

Nucleotide Sequence
(FASTA)

ATGGAGATGT ATGAAAGCCT TGGAAAAGTG GGAGAGGGAA GTTATGGAAC AGTTATGAAG 60

TGTAAACATA AGGAAACTGG GCAGATAGTG GCCATTAAGA TATTTTATGA GAAACCGGAA 120

AAATCTGTCA ACAAAATTGC AACAAGAGAA ATAAAGTTTC TGAAGCAATT TCGTCATGAA 180

AACCTGGTCA ATCTGATTGA AGTTTTTAGA CAGAAAAAGA AAATTCATTT GGTGTTTGAA 240

TTTATTGACC ACACAGTATT AGATGAGTTA CAACATTATT GTCATGGACT AGAGAGTAAA 300

CGACTTAGAA AATACCTCTT CCAGATCCTC CGAGCGATTG AATATCTTCA CGATAATAAT 360

ATCATTCATC GAGATATAAA ACCTGAGAAT ATTTTAGTAT CCCAGTCAGG AATTACTAAA 420

CTCTGTGATT TTGGTTTTGC ACGAACGCTA GCAGCTCCTG GAGACATTTA TACAGACTAT 480

GTAGCCACAC GCTGGTATAG AGCTCCAGAA TTAGTATTAA AAGATACCTC TTACGGAAAA 540

CCTGTGGATA TCTGGGCTTT GGGCTGTATG ATCATTGAGA TGGCCACTGG AAATCCCTAT 600

CTTCCTAGCA GCTCTGATTT GGATTTACTT CATAAAATTG TTTTAAAAGT AGGCAATTTG 660

ACACCTCATT TGCAGAATAT CTTTTCCAAT AATCCCATTT TTGCTGGAGT GGTCCTTCCT 720

CAAGTTCAAC ACCCCAAAAA TGCAAGGAAA AAATATCCAA AGCTAAATGG ATTGTTGGCA 780

GATATAGTTC ATGCTTGTTT ACAAATTGAT CCTGCTGAGA GGATATCGTC TACTGAACTT 840

TTGCATCATG AGTATTTTAC AAGAGATGGA TTTGTTGAAA AATTCATACC GGAACTGAGA 900

GCTAAATTAC TACAAGAAGC AAAAGTCAAT TCATTCATAA AGCCAAAAGA GAATTCTAAA 960

GCAAATGAAC TTATGAAAAA TGAACGAAAA ACAATTTATA CCAATACATT GCTAAGTACT 1020

TCAGTTTTGG GAAAGGAAAT GGAAAAAGAG AAAAAGCCCA AGGAGATCAA AGTCAGAGTT 1080

ATTAAAGTCA AAGGAGGAAA AGGAGATATC TTAGAATCGA AAAAGATGGA GTGTGAAGGT 1140

AGACATTGTC AGCAGGAGGC AACTGAAAAT GCTCATACCA TGTCTCAAGA TGCAAACCCT 1200

ATAATCAATG AATCACCAAA CCCTGTCAAT CCCAGCACTA ACTCTAACGG CATGAAAGAC 1260

AGTCCACATG CTGGAGGTAG TATGATGATG CCACCCATCA ATTTAACTAG CAGTAATTTG 1320

ATGGCTTTAA ATACCAATTC AAAACTTTCC CACTCCAATT CAAGGTCAAC TGAAAGAGCG 1380

AAAAAGAGAC GCACGTCTTT ACAGTCTATT GGACAAGTTG TGTCTAATAG CAGGCAAGAG 1440

GATACAGGTT CCACTCAAAG CCAAATGGAG AAGGGCGTAT TTAATGAGCA AATGGGTCAA 1500

AGTGACCAAA TGGCAAATAG AAACAAAAGG AAGCTTAATT TTTCCAGATC TGACAGGAAA 1560

GAGTTCCATT TCCCAGAACT GCCTTTCACA ATACATTCAA AGGAGATGAA AAGAATGGAA 1620

GTTAAACAGA TAAAAGTGCT GAAGAGGGAA TCGAAGAAAA CAGATTCATC TAAAATACCA 1680

ACTTTACTTA ATGTGGATCA AAATCAAGAG AAACAAGAGA GTGGAGATGG CTACTGTGAG 1740

GGGAAAAGTT TGAAGAGGAA CAGATTT 1767

Domain Profile

S: 1     yeklgkvGeGsyGvvlkcrnkdtgqivaikkfleseddkevkkialreikllkqlkhenl  60

         ye+lgkvGeGsyG+v+kc++k+tgqivaik f+e+++ k+v+kia+reik+lkq++henl

Q: 4     YESLGKVGEGSYGTVMKCKHKETGQIVAIKIFYEKPE-KSVNKIATREIKFLKQFRHENL  62

         9***********************************9.9*********************

S: 61    vnllevfrrkkklylvfeyvdktvldelerypnGveeelvkkilyqilkaiefchknnii  120

         vnl+evfr+kkk++lvfe++d+tvldel++y++G+e+++++k+l+qil+aie++h nnii

Q: 63    VNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIEYLHDNNII  122

         ************************************************************

S: 121   hrdikpenilisksgvvklcdfGfarllaapgdvytdyvatrwyrapellvgdtkyGksv  180

         hrdikpenil+s+sg++klcdfGfar+laapgd+ytdyvatrwyrapel+++dt+yGk+v

Q: 123   HRDIKPENILVSQSGITKLCDFGFARTLAAPGDIYTDYVATRWYRAPELVLKDTSYGKPV  182

         ************************************************************

S: 181   dvwaiGcllaelltGeplfpgksdvdqlykirktlGeliprhqkifsknevfaGvklpev  240

         d+wa+Gc+++e++tG+p++p++sd+d l+ki+ ++G+l+p+ q+ifs+n++faGv+lp+v

Q: 183   DIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLKVGNLTPHLQNIFSNNPIFAGVVLPQV  242

         ************************************************************

S: 241   edleslekkypklnevlldllkkclkldpaerlsceellkheyf  284

         +++++++kkypkln +l+d++++cl++dpaer+s++ell+heyf

Q: 243   QHPKNARKKYPKLNGLLADIVHACLQIDPAERISSTELLHHEYF  286

         *******************************************9

Domain Sequence
(FASTA)

YESLGKVGEG SYGTVMKCKH KETGQIVAIK IFYEKPEKSV NKIATREIKF LKQFRHENLV 60

NLIEVFRQKK KIHLVFEFID HTVLDELQHY CHGLESKRLR KYLFQILRAI EYLHDNNIIH 120

RDIKPENILV SQSGITKLCD FGFARTLAAP GDIYTDYVAT RWYRAPELVL KDTSYGKPVD 180

IWALGCMIIE MATGNPYLPS SSDLDLLHKI VLKVGNLTPH LQNIFSNNPI FAGVVLPQVQ 240

HPKNARKKYP KLNGLLADIV HACLQIDPAE RISSTELLHH EYF 283

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Felis catus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Vicugna pacos"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013