EKS-EQC-00248

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-EQC-00248

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMKL	287.5	8.7E-86	2	208	207

Status

Unreviewed

Ensembl Protein

ENSECAP00000017424

UniProt Accession

F7DHY7;

Protein Name

Protein Synonyms/Alias

Gene Name

BRSK2

Gene Synonyms/Alias

BRSK2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSECAG00000019668	ENSECAP00000017424	ENSECAT00000021172

Organism

Equus caballus

Functional Description

Protein Length

675

Protein Sequence
(FASTA)

QVEREIAILK LIEHPHVLKL HDVYENKKYL YLVLEHVSGG ELFDYLVKKG RLTPKEARKF 60

FRQIISALDF CHSHSICHRD LKPENLLLDE KNNIRIADFG MSLQVGDSLL ETSCGSPHYA 120

CPEVIRGEKY DGRKADVWSC GVILFALLVG ALPFDDDNLR QLLEKVKRGV FHMPHFIPPD 180

CQSLLRGMIE VDAARRLTLE HIQKHTWYIG GKNEPEPEQP IPRKVQIRSL PSLEDIDPDV 240

LDSMHSLGCF RDRNKLLQDL LSEEENQEKM IYFLLLDRKE RYPSHEDEDL PPRNEIDPPR 300

KRVDSPMLNR HGKRRPERKS MEVLSVTDGG SPVPARRAIE MAQHGQRSRS ISGASSGLST 360

SPLSSPRVTP HPSPRGSPLP TPKGTPVHTP KESPAGTPNP TPPSSPSVGG VPWRTRLNSI 420

KNSFLGSPRF HRRKLQVPTP EEMSNLTPES SPELAKKSWF GNFINLEKEE QIFVVIKDKP 480

LSSIKADIVH AFLSARPALL HSVISQTSFR AEYKATGGPA VFQKPVKFQV DITYTEGGAA 540

QKENGIYSVT FTLLSGPSRR FKRVVETIQT QLLSTHDQPS TQHLSDTTNC MEMMTGRLSK 600

CGSPLSNFFD VIKQLFSDEK NGQAAQAPST PAKRSAHSPL GDSAAAGPGP GGDAEYPTGK 660

DMAKTGPPAA RREQP 675

Nucleotide Sequence
(FASTA)

CAGGTAGAGC GGGAGATTGC CATCCTGAAG CTCATCGAGC ACCCTCACGT CCTAAAGCTG 60

CACGACGTTT ATGAAAACAA AAAATATTTA TACCTGGTGC TAGAACACGT GTCTGGAGGT 120

GAGCTCTTCG ACTACCTGGT CAAAAAGGGG AGGCTGACCC CCAAAGAGGC GCGCAAGTTC 180

TTCCGGCAGA TCATCTCGGC GCTAGACTTC TGCCACAGCC ACTCCATATG CCACAGGGAC 240

CTGAAACCAG AGAACTTGCT GCTGGACGAG AAGAACAACA TCCGCATCGC GGACTTCGGG 300

ATGTCCCTGC AGGTGGGCGA CAGCCTGCTG GAGACCAGCT GTGGGTCGCC CCACTATGCC 360

TGCCCCGAGG TGATCCGGGG GGAGAAGTAT GACGGCCGTA AGGCGGACGT GTGGAGCTGC 420

GGGGTGATCC TGTTCGCCTT GCTGGTGGGG GCGCTGCCCT TCGACGACGA CAACCTGCGG 480

CAGCTGCTGG AGAAGGTGAA GCGGGGCGTG TTCCACATGC CGCACTTCAT CCCGCCCGAC 540

TGCCAGAGCC TGCTGCGTGG CATGATCGAG GTGGACGCCG CGCGGCGCCT CACGCTAGAG 600

CACATTCAGA AACACACATG GTATATAGGG GGCAAGAACG AGCCGGAGCC TGAGCAGCCC 660

ATTCCCCGCA AGGTGCAGAT CCGCTCACTG CCCAGCCTGG AGGACATCGA CCCTGATGTG 720

CTGGATAGCA TGCACTCGCT GGGCTGCTTC CGCGACCGCA ACAAGCTGCT GCAGGACCTG 780

CTGTCCGAGG AGGAGAACCA GGAGAAGATG ATCTACTTCC TCCTCCTGGA CCGGAAGGAG 840

AGGTACCCAA GCCACGAGGA CGAGGACCTG CCCCCAAGGA ATGAAATAGA CCCTCCCCGG 900

AAGCGTGTGG ACTCCCCGAT GCTGAACCGG CACGGCAAGC GACGGCCAGA GCGCAAGTCC 960

ATGGAGGTGC TCAGCGTGAC GGACGGTGGC TCCCCGGTGC CCGCACGGAG GGCCATCGAG 1020

ATGGCTCAGC ACGGCCAGAG GTCTAGGTCC ATCAGCGGCG CCTCCTCAGG CCTCTCCACC 1080

AGCCCTCTCA GCAGCCCTCG GGTGACCCCT CACCCCTCTC CAAGGGGCAG TCCCCTCCCC 1140

ACCCCCAAGG GGACGCCCGT GCACACGCCC AAGGAGAGCC CAGCCGGCAC GCCCAACCCC 1200

ACGCCGCCGT CCAGTCCCAG CGTTGGAGGG GTGCCCTGGA GGACACGGCT CAACTCCATC 1260

AAGAACAGCT TCCTGGGGTC GCCCCGCTTC CACCGCCGGA AACTGCAAGT TCCAACGCCA 1320

GAGGAGATGT CCAACCTAAC CCCGGAGTCG TCCCCAGAGC TCGCCAAGAA GTCCTGGTTT 1380

GGGAACTTCA TCAACCTGGA GAAGGAGGAG CAGATCTTCG TGGTCATCAA GGACAAGCCG 1440

CTGAGCTCCA TCAAAGCAGA CATCGTCCAC GCCTTCCTGT CGGCCAGGCC TGCTCTCCTC 1500

CACAGCGTCA TCTCCCAAAC CAGCTTCCGG GCTGAGTACA AGGCAACGGG GGGCCCAGCG 1560

GTGTTCCAGA AGCCAGTCAA GTTCCAGGTG GACATCACCT ACACTGAGGG GGGTGCAGCA 1620

CAGAAGGAGA ATGGCATCTA CTCTGTCACG TTCACGCTTC TGTCAGGCCC TAGCCGCCGC 1680

TTCAAGAGGG TCGTGGAGAC TATTCAGACC CAGCTGCTGA GCACACACGA CCAGCCCTCC 1740

ACCCAGCATT TGTCAGACAC CACTAACTGT ATGGAAATGA TGACGGGGAG GCTTTCCAAA 1800

TGTGGCAGCC CATTGAGTAA CTTCTTTGAC GTAATTAAAC AACTTTTTTC AGACGAGAAG 1860

AACGGGCAGG CGGCCCAGGC CCCCAGCACG CCCGCCAAGC GGAGTGCCCA CAGCCCACTC 1920

GGTGACTCCG CGGCCGCTGG CCCCGGCCCT GGAGGGGACG CCGAGTACCC AACGGGCAAG 1980

GACATGGCCA AGACGGGGCC GCCCGCCGCC CGCCGCGAGC AGCCTTAG 2028

Domain Profile

S: 45    ikrEieilkklkhpniikllevietkkklylvleyasggeLfdyieekgrlkekearklf  104

         ++rEi+ilk ++hp+++kl++v+e+kk+lylvle++sggeLfdy+++kgrl+ keark+f

Q: 2     VEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFF  61

         89**********************************************************

S: 105   kqlvsavkYlhskgivHrDlKpeNllldkkenikiaDFGlanlfkegklletfcGsppYa  164

         +q++sa++++hs++i+HrDlKpeNllld+k+ni+iaDFG++ ++ + +llet+cGsp+Ya

Q: 62    RQIISALDFCHSHSICHRDLKPENLLLDEKNNIRIADFGMSLQVGD-SLLETSCGSPHYA  120

         *****************************************98876.5************

S: 165   aPellkgkkYegpkvDvWslGvvLyalvtgklPfdeenlkellekilkgkleipkklske  224

         +Pe+++g+kY+g+k+DvWs+Gv+L+al++g+lPfd++nl++llek+++g +++p+ + ++

Q: 121   CPEVIRGEKYDGRKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPD  180

         ************************************************************

S: 225   lesLlrklLvvdpekRatieeilkhewl  252

         ++sLlr +++vd+++R+t+e+i+kh+w+

Q: 181   CQSLLRGMIEVDAARRLTLEHIQKHTWY  208

         ***************************5

Domain Sequence
(FASTA)

VEREIAILKL IEHPHVLKLH DVYENKKYLY LVLEHVSGGE LFDYLVKKGR LTPKEARKFF 60

RQIISALDFC HSHSICHRDL KPENLLLDEK NNIRIADFGM SLQVGDSLLE TSCGSPHYAC 120

PEVIRGEKYD GRKADVWSCG VILFALLVGA LPFDDDNLRQ LLEKVKRGVF HMPHFIPPDC 180

QSLLRGMIEV DAARRLTLEH IQKHTWY 207

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Gallus gallus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Otolemur garnettii"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0000287	; F:magnesium ion binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0050321	; F:tau-protein kinase activity
GO:0007409	; P:axonogenesis
GO:0030010	; P:establishment of cell polarity
GO:0018105	; P:peptidyl-serine phosphorylation

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013