EPS-EQC-00022

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-EQC-00022

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	192.6	1.1E-56	7	223	217

Status

Unreviewed

Ensembl Protein

ENSECAP00000018150

UniProt Accession

F6UGB1;

Protein Name

Protein Synonyms/Alias

Gene Name

PPM1L

Gene Synonyms/Alias

PPM1L;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSECAG00000020721	ENSECAP00000018150	ENSECAT00000021987

Organism

Equus caballus

Functional Description

Protein Length

234

Protein Sequence
(FASTA)

MCMPYLQTAA EYVKSRLPEA LKQHLQDYEK DKENSVLSYQ TILEQQILSI DREMLEKLTV 60

SYDEAGTTCL IALLSDKDLT VANVGDSRGV LCDKDGNAIP LSHDHKPYQL KERKRIKRAG 120

GFISFNGSWR VQGILAMSRS LGDYPLKNLN VVIPDPDILT FDLDKLQPEF MILASDGLWD 180

AFSNEEAVRF IKERLDEPHF GAKSIVLQSF YRGCPDNITV MVVKFRNSSK TEEQ 234

Nucleotide Sequence
(FASTA)

ATGTGCATGC CTTATCTGCA GACTGCAGCT GAATATGTAA AATCTCGACT CCCAGAGGCC 60

CTTAAACAGC ATCTTCAGGA CTATGAGAAA GACAAAGAAA ATAGCGTATT GTCTTACCAG 120

ACCATCCTTG AACAGCAGAT TCTGTCAATT GACCGAGAAA TGCTAGAAAA ATTGACTGTA 180

TCCTATGACG AAGCAGGTAC AACATGTTTG ATTGCCCTCC TATCAGATAA AGACCTCACC 240

GTGGCCAACG TGGGTGACTC GAGAGGGGTC CTGTGTGACA AGGACGGGAA TGCCATTCCT 300

TTGTCTCACG ATCACAAGCC TTACCAACTG AAGGAAAGAA AGAGGATCAA GAGAGCTGGA 360

GGTTTCATCA GTTTCAATGG CTCCTGGAGG GTCCAGGGAA TCCTGGCCAT GTCTCGATCC 420

CTGGGGGATT ATCCACTGAA AAACCTCAAC GTGGTCATCC CAGACCCAGA TATCCTAACC 480

TTTGACCTGG ACAAGCTCCA GCCTGAGTTC ATGATCTTGG CATCAGATGG CCTCTGGGAT 540

GCTTTCAGCA ATGAAGAAGC TGTCCGATTC ATCAAGGAGC GCTTGGATGA ACCTCACTTT 600

GGGGCCAAGA GCATAGTTTT GCAGTCATTT TACAGAGGCT GCCCTGACAA TATAACAGTC 660

ATGGTGGTGA AGTTCAGGAA TAGCAGCAAA ACAGAAGAGC AGTGA 705

Domain Profile

S: 47    sevakfcseklheilaeele....sseseerkvkkalakaFlstdeelkvleeksldidk  102

         +++a++++++l e+l++ l+    ++e++    +++l++  ls+d+e+  le+ + + d+

Q: 7     QTAAEYVKSRLPEALKQHLQdyekDKENSVLSYQTILEQQILSIDREM--LEKLTVSYDE  64

         6899**************99654333334444459*************..999999****

S: 103   sGstavvalikdsklyvanvGdSravLcr.ngkavelssdHkpsredEleRieeaggsvi  161

          G+t+++al++d++l+vanvGdSr vLc+ +g+a++ls dHkp + +E++Ri++agg +

Q: 65    AGTTCLIALLSDKDLTVANVGDSRGVLCDkDGNAIPLSHDHKPYQLKERKRIKRAGGFIS  124

         *****************************566************************9999

S: 162   lkdga.RvlGvLavsRalGdlylk..pyvtpePevtshrltsede.fliLasDGlwdvvs  217

          + g  Rv+G La+sR+lGd+ lk   +v+p+P++  ++l++ +  f+iLasDGlwd +s

Q: 125   FN-GSwRVQGILAMSRSLGDYPLKnlNVVIPDPDILTFDLDKLQPeFMILASDGLWDAFS  183

         77.667******************8889************765544**************

S: 218   neeavslvrdvlekkeaeqeaakkLvklalargskdnvsaivv  260

         neeav++++++l+   ++   ak++v ++  rg+ dn++++vv

Q: 184   NEEAVRFIKERLD---EPHFGAKSIVLQSFYRGCPDNITVMVV  223

         *************...999********************9997

Domain Sequence
(FASTA)

QTAAEYVKSR LPEALKQHLQ DYEKDKENSV LSYQTILEQQ ILSIDREMLE KLTVSYDEAG 60

TTCLIALLSD KDLTVANVGD SRGVLCDKDG NAIPLSHDHK PYQLKERKRI KRAGGFISFN 120

GSWRVQGILA MSRSLGDYPL KNLNVVIPDP DILTFDLDKL QPEFMILASD GLWDAFSNEE 180

AVRFIKERLD EPHFGAKSIV LQSFYRGCPD NITVMVV 217

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0004722	; F:protein serine/threonine phosphatase activity
GO:0000165	; P:MAPK cascade
GO:0008152	; P:metabolic process
GO:0007178	; P:transmembrane receptor protein serine/threonine kinase signaling pathway

KEGG

InterPros

IPR001932	; PP2C-like.
IPR015655	; Protein_Pase_2C.

Pfam

PF00481

; PP2C; 1.

SMARTs

SM00331	; PP2C_SIG; 1.
SM00332	; PP2Cc; 1.

Prosites

Prints

Created Date

20-Feb-2013