EKS-EQC-00058

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-EQC-00058

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	392.0	1.6E-117	195	476	282

Status

Unreviewed

Ensembl Protein

ENSECAP00000019638

UniProt Accession

F6Z1J1;

Protein Name

Protein Synonyms/Alias

Gene Name

CDK17

Gene Synonyms/Alias

CDK17;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSECAG00000021679	ENSECAP00000019638	ENSECAT00000023693

Organism

Equus caballus

Functional Description

Protein Length

526

Protein Sequence
(FASTA)

IDRMKKFKRR LSLTLRGSQT IDESLSELAE QMTIEENSNK DNEPIVKNGR PPTSHSMHSF 60

LHQYTGSFKK PPLRRPHSVI GGSLGSFMAM PRNGSRLDIV HENLKMGSDG ESDQASGTSS 120

DEVQSPTGVC LRNRIHRRIS MEDLNKRLSL PADIRIPDGY LEKLQINSPP FDQPMSRRSR 180

RASLSEIGFG KMETYIKLEK LGEGTYATVY KGRSKLTENL VALKEIRLEH EEGAPCTAIR 240

EVSLLKDLKH ANIVTLHDIV HTDKSLTLVF EYLDKDLKQY MDDCGNIMSM HNVKLFLYQI 300

LRGLAYCHRR KVLHRDLKPQ NLLINEKGEL KLADFGLARA KSVPTKTYSN EVVTLWYRPP 360

DVLLGSSEYS TQIDMWGVGC IFFEMASGRP LFPGSTVEDE LHLIFRLLGT PSQETWPGVS 420

SNDEFKNYNF PKYKPQPLIN HAPRLDSEGI ELITKFLQYE SKKRVSAEEA MKHVYFRSLG 480

PRIHALPESV SIFSLKEIQL QKDPGFRNSS YPETGHGKNR RQSMLF 526

Nucleotide Sequence
(FASTA)

ATTGATAGGA TGAAAAAGTT TAAGAGAAGA CTATCCCTCA CGCTTCGAGG AAGCCAGACT 60

ATTGATGAAT CATTGTCTGA ACTGGCTGAA CAAATGACTA TTGAAGAAAA CAGCAACAAG 120

GATAATGAGC CAATTGTGAA GAATGGCAGG CCTCCAACCT CTCACAGTAT GCATTCCTTC 180

CTCCACCAGT ACACAGGATC CTTCAAGAAG CCCCCATTGC GGAGACCACA TAGCGTTATT 240

GGAGGAAGCC TTGGCTCCTT CATGGCGATG CCTAGAAATG GAAGCAGATT AGATATTGTT 300

CATGAAAATC TAAAAATGGG ATCAGATGGT GAGAGTGACC AAGCTTCTGG GACATCATCT 360

GATGAAGTCC AGTCACCTAC AGGTGTTTGT CTTAGAAATC GTATACATAG ACGGATCTCA 420

ATGGAGGATT TAAATAAGCG GTTATCACTG CCTGCAGATA TCAGAATACC TGATGGATAT 480

CTTGAAAAAT TGCAGATAAA CAGTCCACCG TTTGATCAAC CAATGAGCCG AAGGTCTCGG 540

AGAGCTTCCT TATCAGAAAT TGGGTTTGGG AAAATGGAAA CCTACATCAA ATTGGAAAAA 600

CTTGGAGAGG GTACATATGC AACAGTATAT AAAGGAAGAA GTAAACTGAC AGAGAATTTG 660

GTGGCATTAA AAGAGATCCG GTTGGAACAT GAAGAAGGTG CACCCTGCAC AGCTATAAGA 720

GAAGTTTCGC TATTAAAGGA TCTAAAACAT GCAAATATAG TAACCTTACA TGACATTGTT 780

CACACAGATA AATCTTTGAC TCTGGTCTTT GAGTATCTGG ATAAAGACCT AAAACAGTAC 840

ATGGATGACT GTGGAAACAT CATGAGTATG CACAATGTGA AGCTGTTTTT ATACCAAATT 900

CTACGTGGTT TGGCATATTG CCACAGAAGA AAAGTGTTGC ACCGAGACTT GAAACCACAG 960

AACCTCCTGA TTAATGAAAA AGGAGAATTA AAGCTAGCAG ATTTTGGACT AGCCAGAGCC 1020

AAGTCAGTTC CCACAAAGAC CTACTCAAAT GAAGTTGTCA CACTGTGGTA CCGGCCACCT 1080

GATGTGCTTC TTGGTTCCTC AGAGTACTCA ACACAGATCG ACATGTGGGG TGTTGGTTGC 1140

ATTTTCTTTG AAATGGCTTC TGGAAGACCT CTATTTCCAG GATCAACTGT TGAAGATGAA 1200

CTGCACTTAA TCTTCCGACT GCTAGGAACT CCATCTCAGG AAACTTGGCC AGGTGTTTCT 1260

TCAAATGATG AGTTCAAGAA CTACAACTTT CCAAAATATA AACCACAGCC TCTAATTAAC 1320

CATGCACCCA GATTAGACTC TGAAGGAATC GAGTTGATAA CAAAATTTCT TCAGTATGAA 1380

TCTAAGAAAA GGGTTTCAGC AGAAGAGGCC ATGAAACATG TGTACTTTCG AAGTCTGGGA 1440

CCAAGAATAC ATGCTTTACC TGAAAGTGTA TCAATATTCA GTTTGAAAGA GATTCAGTTG 1500

CAAAAGGACC CGGGTTTTCG AAATTCTTCT TATCCAGAGA CAGGACATGG GAAGAACAGA 1560

AGACAGAGCA TGCTCTTTTA A 1581

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkelkhkni  60

         y klek+geGty++vyk+++k t+++vAlK+irle+e eg p+ta+rE+sllk+lkh+ni

Q: 195   YIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHE-EGAPCTAIREVSLLKDLKHANI  253

         7799********************************9.9*********************

S: 61    vkLlevvakdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqlleglaylHsnk  120

         v+L+++v+ ++k+l+Lvfe+l++dLk++++++ +  +s+++vk +l+q+l+glay+H++k

Q: 254   VTLHDIVH-TDKSLTLVFEYLDKDLKQYMDDCGN-IMSMHNVKLFLYQILRGLAYCHRRK  311

         ********.99***********************.*************************

S: 121   ilHRDlKpqNlLiskegklklaDfGlarafssplktytkevvTlwYraPelLlgakeYst  180

         +lHRDlKpqNlLi+++g+lklaDfGlara s+p+kty++evvTlwYr+P++Llg++eYst

Q: 312   VLHRDLKPQNLLINEKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSEYST  371

         ************************************************************

S: 181   avDiWsvgcilaelltrkplfqgkseidqlerifkllgtpsekvwpevsklpeyk.ksfp  239

         ++D+W+vgci+ e+++ +plf+g++  d+l+ if+llgtps+++wp+vs+  e+k ++fp

Q: 372   QIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQETWPGVSSNDEFKnYNFP  431

         *******************************************************99***

S: 240   kkkkkklkekvkklkekaldllekllaldpkkRisakealqhkyf  284

         k+k++ l ++ ++l++++++l++k+l+++ kkR+sa+ea++h yf

Q: 432   KYKPQPLINHAPRLDSEGIELITKFLQYESKKRVSAEEAMKHVYF  476

         ********************************************8

Domain Sequence
(FASTA)

YIKLEKLGEG TYATVYKGRS KLTENLVALK EIRLEHEEGA PCTAIREVSL LKDLKHANIV 60

TLHDIVHTDK SLTLVFEYLD KDLKQYMDDC GNIMSMHNVK LFLYQILRGL AYCHRRKVLH 120

RDLKPQNLLI NEKGELKLAD FGLARAKSVP TKTYSNEVVT LWYRPPDVLL GSSEYSTQID 180

MWGVGCIFFE MASGRPLFPG STVEDELHLI FRLLGTPSQE TWPGVSSNDE FKNYNFPKYK 240

PQPLINHAPR LDSEGIELIT KFLQYESKKR VSAEEAMKHV YF 282

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013