EKS-EQC-00473

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-EQC-00473

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/RSKL	306.0	5.0E-91	882	1057	176

Status

Unreviewed

Ensembl Protein

ENSECAP00000019244

UniProt Accession

F6Y142;

Protein Name

Protein Synonyms/Alias

Gene Name

RPS6KC1

Gene Synonyms/Alias

RPS6KC1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSECAG00000021706	ENSECAP00000019244	ENSECAT00000023249

Organism

Equus caballus

Functional Description

Protein Length

1067

Protein Sequence
(FASTA)

MTSPRERGAD LARFYTVTDP QRHPRGYTVY KVTARVVSRR NPEDVQEIIV WKRYSDFKKL 60

HKELWQIHKN LFRHSELFPP FAKGIVFGRF DGAVIEERRQ CAEDLLQFSA SIPALYNSKQ 120

LADFFKGGII NDGSELIGPA EAYSDSLTDN FPECSTEGFS SDSDLVSLTV DVDSLAELDD 180

GMASNQNSPI RTFGLNQSSD SSALGAVASD SEQNKAEEER ESRSLFPGSL KSKLGKRDYL 240

EKAGELIKLA LKKEEEDDYE AASDFYRKGV DLLLEGVQGE SSPTRREAVK RRTAEYLMRA 300

ESLCSLYKGK PQLDDVAQPP GSLSSRPPWN LRSPAEELKA FRVLGVIDKV LLVVDTRTEQ 360

TFILKGLRKS SEYSRNRKTI IPRCVPNMVC LHKYIVSEES VFLVLQHAEG GKLWSYISKF 420

LNRSLEESFD IEEVKKSTLS KVHLQQPTSG PRDSSSFESR GSDGGTMLKV LPLKTSLTPS 480

SQEDSYQDDD GQDSSPKWPD SGSSSEEECT TSYLTLCNEY GQEKIEPGSL SEEPFMKTEG 540

IGVDTKAIES FPACLAPDSD SPSTQLIAHE LKFFPGDDGL EAVSPPGTSD SLSRSKNSPM 600

EFFRIDSKDS TSELLGLDFG EKLYSRKSEP LKPFFTLPDG DSTSRSFSIS ESKVELIAQD 660

TISRGSDDSV PVISFKDAAF DDLSGTDEGR PDLLVNLPGE LEPPKDGAAM GPTKFVQTNI 720

GIMESKLLEA PDVLCLRLST EQCQAYEEKG TEELSDPSRP KSHSLTEKHY AQGELGMLFA 780

AAVDHCSSGD RSLLHSSDPK FQGLGVVASA VTANSTEESL FHISNPLSGA NEYNANTETL 840

KTEEVLLFTD QTDDLAKEEP TLFQRDYETR GDSGLALQGD KEIHHIFEDL DKKLALNSRF 900

YIPEGCIQRW AAEMVVALDA LHREGIVCRD LNPNNILLND RGHIQLTYFS RWSEVEDSCD 960

SDAIERMYCA PEVGAITEET EACDWWSLGA VLFELLTGKT LVECHPAGIN THTTLNMPEC 1020

VSEEARSLIQ QLLQFNPVER LGAGVAGVED IKSHPFFTPV DWAELMR 1067

Nucleotide Sequence
(FASTA)

ATGACCTCTC CTCGGGAGCG GGGTGCCGAC CTCGCCCGTT TCTACACTGT CACCGATCCC 60

CAGCGACACC CGAGGGGCTA CACGGTGTAT AAGGTCACCG CCCGGGTTGT TTCACGAAGA 120

AATCCAGAGG ATGTCCAGGA GATAATCGTA TGGAAGAGAT ACAGTGACTT TAAGAAACTA 180

CACAAAGAAC TATGGCAAAT TCACAAAAAC TTATTTCGAC ACTCAGAATT GTTTCCTCCC 240

TTTGCTAAAG GAATCGTGTT TGGACGGTTT GATGGAGCTG TGATTGAAGA GAGAAGACAG 300

TGTGCCGAAG ACCTGCTGCA GTTCTCTGCC AGTATTCCCG CTCTTTACAA CAGCAAACAG 360

CTTGCAGACT TTTTCAAGGG TGGGATAATT AATGATGGTT CTGAATTGAT TGGTCCTGCT 420

GAAGCCTATT CGGATTCCCT CACTGATAAT TTTCCTGAGT GTAGTACAGA AGGCTTCTCC 480

AGCGACAGCG ATCTTGTATC TCTTACTGTT GATGTGGATT CTCTTGCTGA GTTAGATGAT 540

GGAATGGCTT CCAATCAAAA TTCTCCCATT AGAACTTTTG GTCTCAACCA GTCTTCAGAT 600

TCTTCAGCGC TAGGAGCTGT TGCTTCTGAC AGCGAACAGA ACAAAGCCGA AGAAGAACGG 660

GAAAGTCGTA GCCTCTTTCC CGGCAGTTTA AAATCCAAGC TTGGCAAGAG AGATTATTTG 720

GAGAAAGCAG GAGAATTAAT AAAGCTGGCT TTAAAAAAGG AAGAAGAAGA CGACTATGAA 780

GCTGCCTCTG ATTTTTATAG GAAGGGAGTT GATTTACTCC TAGAAGGTGT TCAAGGAGAG 840

TCAAGTCCTA CCCGTCGAGA AGCTGTGAAG AGAAGAACAG CCGAGTATCT CATGCGAGCG 900

GAGAGTCTCT GTAGCCTTTA TAAAGGAAAA CCTCAACTTG ATGACGTAGC TCAGCCTCCA 960

GGATCACTAA GTTCAAGGCC CCCTTGGAAC CTAAGGAGCC CTGCCGAGGA GCTGAAGGCC 1020

TTCAGAGTCC TTGGGGTGAT TGACAAGGTT TTACTTGTAG TGGACACAAG GACAGAGCAG 1080

ACATTCATTT TAAAGGGTCT AAGGAAAAGC AGTGAATACA GCAGGAACAG AAAGACCATC 1140

ATCCCCCGCT GTGTGCCCAA CATGGTGTGT CTGCACAAGT ACATCGTTTC TGAGGAGTCG 1200

GTGTTTCTTG TGCTGCAGCA CGCAGAAGGT GGCAAACTCT GGTCATATAT CAGTAAATTT 1260

CTAAACAGAA GTCTTGAAGA AAGCTTTGAC ATCGAGGAAG TGAAAAAATC TACACTTAGT 1320

AAAGTTCACC TGCAACAGCC GACTTCTGGT CCTCGGGACA GCAGCAGCTT TGAATCCAGA 1380

GGAAGTGATG GTGGAACCAT GCTTAAAGTT CTGCCCTTGA AGACTAGTCT TACTCCAAGC 1440

TCTCAAGAGG ATAGCTACCA AGATGATGAT GGCCAAGATA GCTCTCCAAA ATGGCCAGAT 1500

TCTGGCTCAA GTTCAGAAGA AGAATGTACT ACTAGTTATT TAACATTATG CAATGAATAT 1560

GGGCAAGAAA AGATTGAACC AGGGTCATTG AGTGAGGAGC CTTTCATGAA GACTGAAGGG 1620

ATTGGTGTTG ATACCAAAGC TATTGAAAGC TTCCCGGCAT GCCTTGCTCC TGACAGCGAC 1680

AGCCCTAGCA CACAGCTGAT AGCTCACGAG CTAAAGTTCT TCCCTGGAGA TGATGGCCTA 1740

GAAGCAGTTA GTCCTCCAGG AACATCAGAT TCCCTCAGTA GATCTAAAAA CAGCCCCATG 1800

GAATTCTTTA GAATAGACAG TAAGGATAGC ACTAGTGAAC TCCTAGGACT TGATTTTGGA 1860

GAAAAATTGT ATAGTCGAAA GTCAGAGCCT TTGAAACCAT TTTTCACTCT TCCAGATGGA 1920

GACAGCACTT CCAGGAGTTT TAGTATTAGT GAAAGCAAGG TAGAGTTGAT AGCTCAGGAC 1980

ACCATTAGCA GGGGCTCAGA TGATTCAGTC CCAGTTATTT CTTTTAAAGA TGCTGCTTTC 2040

GATGATCTCA GTGGTACAGA TGAAGGAAGG CCTGATCTTC TTGTAAATCT ACCTGGTGAA 2100

TTGGAGCCAC CAAAAGATGG TGCAGCAATG GGACCTACTA AATTTGTACA GACTAATATA 2160

GGCATAATGG AAAGTAAACT ATTGGAAGCC CCCGATGTTT TATGCCTCAG GCTTAGTACG 2220

GAACAGTGCC AAGCATATGA AGAAAAAGGC ACAGAGGAAT TGAGTGATCC CTCTAGGCCT 2280

AAATCCCATA GTTTAACAGA GAAACACTAT GCACAGGGCG AGCTTGGGAT GTTATTTGCA 2340

GCAGCTGTTG ATCACTGTAG TTCAGGAGAC AGGTCTTTGT TACACAGCTC AGATCCTAAG 2400

TTTCAAGGGC TTGGAGTGGT TGCATCGGCT GTAACTGCAA ACAGCACAGA AGAAAGCTTA 2460

TTCCATATTT CTAACCCACT CTCAGGTGCT AATGAGTATA ATGCAAACAC GGAGACTTTA 2520

AAAACTGAAG AAGTATTGCT GTTTACAGAT CAAACTGATG ATTTGGCTAA AGAGGAACCG 2580

ACTTTATTCC AGAGAGACTA TGAGACTAGG GGAGACAGTG GGTTAGCACT ACAAGGAGAC 2640

AAGGAAATAC ATCACATTTT TGAGGACCTT GATAAAAAAT TAGCACTAAA CTCCAGGTTT 2700

TACATCCCAG AGGGCTGCAT TCAAAGATGG GCAGCTGAAA TGGTGGTAGC CCTTGATGCT 2760

CTGCATAGAG AGGGAATTGT GTGCCGCGAT TTGAACCCAA ACAACATCTT ATTGAATGAT 2820

AGAGGACACA TTCAGCTAAC GTATTTTAGC AGGTGGAGTG AGGTTGAAGA TTCCTGTGAC 2880

AGCGATGCCA TAGAGAGAAT GTACTGTGCC CCAGAGGTTG GAGCAATCAC GGAGGAAACT 2940

GAAGCCTGTG ATTGGTGGAG TTTGGGCGCT GTCCTCTTTG AACTTCTCAC TGGCAAGACT 3000

CTGGTTGAGT GCCATCCAGC AGGAATAAAT ACTCACACTA CTTTGAACAT GCCGGAATGT 3060

GTCTCTGAAG AGGCTCGCTC ACTCATTCAA CAGCTCTTGC AGTTCAACCC TGTGGAGCGA 3120

CTTGGTGCTG GAGTTGCTGG TGTTGAAGAT ATCAAATCTC ATCCATTTTT CACCCCTGTG 3180

GATTGGGCAG AGCTGATGAG ATGA 3204

Domain Profile

S: 189   eiklvsedadkslealsrgldkalqsvdkalslrravwslpEelikqWaaelvvaleaLH  248

         ei+ ++ed+dk+l++ sr                   +++pE++i++Waae+vval+aLH

Q: 882   EIHHIFEDLDKKLALNSR-------------------FYIPEGCIQRWAAEMVVALDALH  922

         444444444444444444...................99*********************

S: 249   eegvlirDlnadniLldskGhllltYfgrwsevekscrreavdnlysAPEvgaiseltea  308

         +eg+++rDln++niLl+++Gh++ltYf+rwseve+sc+++a++++y+APEvgai+e+tea

Q: 923   REGIVCRDLNPNNILLNDRGHIQLTYFSRWSEVEDSCDSDAIERMYCAPEVGAITEETEA  982

         ************************************************************

S: 309   sDwWslGalLyelLtGkalaeahPsgiqahtelqlPevvSeeAkdLleeLLqfePalRlG  368

         +DwWslGa+L+elLtGk+l+e+hP+gi++ht+l++Pe+vSeeA++L+++LLqf+P +RlG

Q: 983   CDWWSLGAVLFELLTGKTLVECHPAGINTHTTLNMPECVSEEARSLIQQLLQFNPVERLG  1042

         ************************************************************

S: 369   aGeagvdelkaHPFF  383

         aG+agv+++k+HPFF

Q: 1043  AGVAGVEDIKSHPFF  1057

         **************9

Domain Sequence
(FASTA)

EIHHIFEDLD KKLALNSRFY IPEGCIQRWA AEMVVALDAL HREGIVCRDL NPNNILLNDR 60

GHIQLTYFSR WSEVEDSCDS DAIERMYCAP EVGAITEETE ACDWWSLGAV LFELLTGKTL 120

VECHPAGINT HTTLNMPECV SEEARSLIQQ LLQFNPVERL GAGVAGVEDI KSHPFF 176

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005769	; C:early endosome
GO:0005524	; F:ATP binding
GO:0035091	; F:phosphatidylinositol binding
GO:0004672	; F:protein kinase activity
GO:0007154	; P:cell communication

KEGG

ecb:100050383

;

InterPros

IPR011009	; Kinase-like_dom.
IPR007330	; MIT.
IPR001683	; Phox.
IPR000719	; Prot_kinase_cat_dom.

Pfam

PF04212	; MIT; 1.
PF00069	; Pkinase; 1.
PF00787	; PX; 1.

SMARTs

SM00745	; MIT; 1.
SM00312	; PX; 1.

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS50195	; PX; 1.

Prints

Created Date

20-Feb-2013