EKS-EQC-00419

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-EQC-00419

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/WEE	327.6	5.8E-98	105	353	249

Status

Unreviewed

Ensembl Protein

ENSECAP00000020376

UniProt Accession

F6VTL4;

Protein Name

Protein Synonyms/Alias

Gene Name

PKMYT1

Gene Synonyms/Alias

PKMYT1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSECAG00000022901	ENSECAP00000020376	ENSECAT00000024523

Organism

Equus caballus

Functional Description

Protein Length

497

Protein Sequence
(FASTA)

PVPAMPVPTE GTPPPLSGTP VPVPAYFRHA EPGFSLKRPR GLSRSLPPRP PAKGSIPLSR 60

LFPPRLPGWQ RLEPRRVSFR GEASETLQSP GYDPRRPESF FQQSFQRLGR LGRGSYGEVF 120

KVRSKEDGRL YAVKRSMSPF RGPKDRARKL AEVGGHEKVG QHPRCVRLEQ AWEEGGILYL 180

QTELCGPSLQ QHCEAWGASL PEAQVWGYLR DTLLALAHLH GQGLVHLDVK PANIFLGPRG 240

RCKLGDFGLL VELGASGAGE AQEGDPRYMA PELLQGSYGT AADVFSLGLT ILEVACNMEL 300

PHGGKGWQQL RQGYLPPEFT ASLSSELRSV LVMMLEPDPK LRATAEALLA LPMLRQPRPW 360

SVLWYMAAEA LSRGWALWQA LLALLCWLWH GLAHPASWLQ PPGPPATPPG SPPCSLLLDS 420

SLSSNWDDES IGPSLFPEAV LARAAGTTST PCSSSPAPRS RDGLDLSDTD SEPPRGSFPS 480

FEPRNLLSLF EDSLGPT 497

Nucleotide Sequence
(FASTA)

CCTGTGCCGG CCATGCCTGT GCCCACAGAG GGCACCCCGC CACCCTTGAG TGGCACCCCG 60

GTCCCAGTCC CAGCCTACTT CCGCCACGCA GAACCCGGCT TCTCCCTCAA GAGGCCCCGG 120

GGGCTCAGTC GGAGCCTCCC ACCCCGGCCT CCTGCCAAGG GCAGCATCCC TCTCAGCCGC 180

CTCTTCCCCC CTCGGCTCCC GGGCTGGCAG CGGCTCGAGC CCCGGAGAGT GTCGTTCCGA 240

GGCGAGGCCT CCGAGACCCT GCAGAGCCCC GGCTATGACC CGAGGCGGCC AGAGTCCTTC 300

TTCCAGCAGA GTTTCCAGAG GCTCGGCCGC CTGGGCCGCG GCTCTTACGG AGAAGTCTTC 360

AAGGTGCGCT CCAAGGAAGA CGGTCGTCTT TATGCAGTAA AGCGCTCCAT GTCACCATTC 420

CGGGGCCCCA AGGACCGGGC CCGCAAGCTG GCCGAGGTCG GTGGCCATGA GAAGGTGGGG 480

CAGCACCCGC GCTGCGTGCG GCTAGAGCAA GCCTGGGAGG AGGGCGGCAT CCTGTACCTG 540

CAGACGGAGC TGTGCGGGCC CAGCCTGCAG CAGCACTGTG AGGCCTGGGG CGCCAGCCTG 600

CCTGAGGCCC AGGTCTGGGG CTACCTGCGG GACACCCTGC TTGCCCTGGC CCACCTGCAT 660

GGCCAAGGCC TGGTCCACCT TGATGTCAAG CCTGCCAATA TCTTCCTGGG GCCCCGGGGC 720

CGCTGCAAAC TGGGTGACTT TGGGTTGCTG GTGGAGCTGG GTGCGTCTGG AGCCGGTGAG 780

GCCCAGGAGG GAGACCCCCG CTACATGGCA CCTGAGCTGC TGCAGGGCTC CTACGGGACG 840

GCGGCGGACG TGTTCAGTCT GGGTCTCACC ATCCTGGAAG TGGCATGCAA CATGGAGCTG 900

CCGCATGGTG GAAAGGGCTG GCAGCAGCTG CGCCAGGGCT ACCTGCCCCC TGAGTTCACT 960

GCCAGCCTGT CTTCTGAGCT GCGTTCTGTC CTTGTCATGA TGCTGGAGCC TGACCCCAAG 1020

CTGCGAGCCA CAGCGGAGGC CCTGCTGGCC CTGCCTATGC TCCGGCAGCC ACGGCCCTGG 1080

AGCGTCCTGT GGTACATGGC TGCCGAAGCC CTGAGTCGAG GGTGGGCCCT GTGGCAGGCC 1140

CTGCTGGCCC TGCTGTGCTG GCTCTGGCAC GGGCTGGCTC ACCCTGCCAG CTGGCTGCAG 1200

CCTCCGGGCC CGCCGGCCAC CCCACCTGGC TCGCCGCCCT GCAGCCTCCT CCTGGACAGC 1260

AGCCTTTCCA GCAACTGGGA TGACGAGAGC ATAGGGCCCT CACTCTTTCC AGAGGCTGTC 1320

CTAGCCAGGG CTGCCGGGAC CACCTCCACC CCCTGCAGCA GCTCCCCTGC CCCCCGAAGC 1380

AGGGATGGCC TGGACCTAAG TGACACTGAC TCAGAGCCCC CTCGGGGCTC CTTCCCCTCC 1440

TTTGAGCCTC GGAACCTCCT CAGCCTCTTT GAGGACTCAC TGGGCCCAAC CTGA 1494

Domain Profile

S: 1     FeevekiGkGefgevfkvvkredgklyAikkskkplkglskekkalrEvtahavlgqhen  60

         F+++ ++G+G++gevfkv+++edg+lyA+k+s++p++g ++++++l+Ev +h+++gqh+

Q: 105   FQRLGRLGRGSYGEVFKVRSKEDGRLYAVKRSMSPFRGPKDRARKLAEVGGHEKVGQHPR  164

         89999*******************************************************

S: 61    vvryisaWeeddslyiqtElCeggsLeaalqeceakkkaleeaelkkilldlllglrylH  120

         +vr+ +aWee ++ly+qtElC g sL+++   cea+ ++l+ea+++ +l d ll+l +lH

Q: 165   CVRLEQAWEEGGILYLQTELC-GPSLQQH---CEAWGASLPEAQVWGYLRDTLLALAHLH  220

         *********************.*******...****************************

S: 121   ssslvHlDikpenifitkevtlklgDlGlvtelnsedkskveEGDsrylakEilqeeysk  180

          + lvHlD+kp+nif+  ++++klgD+Gl++el+++ + +++EGD ry+a+E+lq++y +

Q: 221   GQGLVHLDVKPANIFLGPRGRCKLGDFGLLVELGASGAGEAQEGDPRYMAPELLQGSYGT  280

         ************************************************************

S: 181   lkaDiFslgltilevaanvelPsnGeaWhklRkgklpdeilkelsedlrellklmlepdp  240

         + aD+Fslgltileva+n+elP+ G+ W++lR+g+lp+e++++ls++lr++l +mlepdp

Q: 281   A-ADVFSLGLTILEVACNMELPHGGKGWQQLRQGYLPPEFTASLSSELRSVLVMMLEPDP  339

         *.**********************************************************

S: 241   erRptaeellkhev  254

         + R+tae+ll+ ++

Q: 340   KLRATAEALLALPM  353

         **********9876

Domain Sequence
(FASTA)

FQRLGRLGRG SYGEVFKVRS KEDGRLYAVK RSMSPFRGPK DRARKLAEVG GHEKVGQHPR 60

CVRLEQAWEE GGILYLQTEL CGPSLQQHCE AWGASLPEAQ VWGYLRDTLL ALAHLHGQGL 120

VHLDVKPANI FLGPRGRCKL GDFGLLVELG ASGAGEAQEG DPRYMAPELL QGSYGTAADV 180

FSLGLTILEV ACNMELPHGG KGWQQLRQGY LPPEFTASLS SELRSVLVMM LEPDPKLRAT 240

AEALLALPM 249

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005737	; C:cytoplasm
GO:0005634	; C:nucleus
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0010923	; P:negative regulation of phosphatase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013