EPS-EQC-00014

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-EQC-00014

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
DSP/aDSP	65.6	4.7E-18	88	200	113

Status

Unreviewed

Ensembl Protein

ENSECAP00000020812

UniProt Accession

F6WA76;

Protein Name

Protein Synonyms/Alias

Gene Name

DUSP11

Gene Synonyms/Alias

DUSP11;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSECAG00000023353	ENSECAP00000020812	ENSECAT00000025028

Organism

Equus caballus

Functional Description

Protein Length

332

Protein Sequence
(FASTA)

MSHWHDAGGR RVQGRIVSRR SSSKKKGGNR IPERWKDYLA VGQRMPGTRF IAFKVPLKKN 60

FEEKLAPEEC FSPLDLFTKI REQNEELGLI IDLTYTHRYY KPEDLPETIP YLKIYTIGHQ 120

VPDDDTIFKF KCAVNGFLKD NKDNDKLIGV HCTHGLNRTG YLICRYLIDV EGMRPDAAIE 180

LFNRCRGHCL ERQNYIEDLQ NGPIRKNWDS SVSRSSGSED LTHMMEPVHT SNKFVSQGPR 240

YELHRTQGYP VPSRHFHTQT QDLQQSVRKF SQSQNIYRRG RIPPPGPPGE DYSQRRYSWN 300

AKPSARPAAQ NEGWYPGSYY RLPYPTHWGW TE 332

Nucleotide Sequence
(FASTA)

ATGAGCCACT GGCATGATGC CGGCGGCCGC CGCGTCCAGG GACGTATCGT TTCCCGACGT 60

TCGTCATCCA AGAAGAAGGG CGGAAACCGC ATCCCCGAAA GGTGGAAAGA CTATCTCGCA 120

GTTGGACAGC GGATGCCTGG CACTCGTTTC ATTGCTTTCA AAGTTCCTTT GAAAAAGAAT 180

TTTGAAGAGA AGCTTGCTCC AGAAGAATGT TTTTCCCCCT TAGATCTTTT TACAAAAATC 240

CGAGAGCAGA ATGAAGAACT TGGACTGATT ATTGATTTAA CATACACTCA CCGCTATTAT 300

AAACCAGAGG ACTTGCCAGA AACTATTCCT TACTTAAAGA TTTATACGAT CGGGCATCAG 360

GTACCCGATG ATGACACTAT TTTTAAATTC AAATGTGCTG TTAATGGGTT TTTGAAAGAC 420

AATAAAGATA ATGACAAACT TATTGGCGTC CACTGTACCC ATGGTTTAAA CAGGACTGGC 480

TACCTCATCT GCAGGTATTT GATTGATGTA GAAGGCATGA GGCCAGATGC TGCAATTGAA 540

TTATTCAATA GGTGCCGGGG ACATTGCTTA GAAAGGCAAA ACTACATTGA AGACCTTCAG 600

AATGGGCCCA TCAGAAAGAA TTGGGATTCC AGTGTATCCA GATCAAGTGG TTCTGAAGAC 660

TTGACACATA TGATGGAACC AGTGCACACC TCTAATAAGT TTGTTAGCCA AGGACCTAGG 720

TATGAGCTAC ATCGAACCCA AGGTTACCCA GTACCTTCTC GGCATTTCCA CACCCAGACT 780

CAAGATTTGC AGCAGTCAGT AAGAAAATTT TCACAGAGTC AGAACATTTA TCGGAGAGGC 840

CGTATCCCTC CTCCTGGGCC TCCTGGAGAG GACTATTCAC AGAGGAGGTA CTCTTGGAAC 900

GCAAAGCCAA GTGCCAGGCC AGCAGCCCAG AATGAAGGCT GGTATCCTGG CAGTTACTAC 960

CGACTTCCGT ACCCAACCCA CTGGGGATGG ACCGAGTGA 999

Domain Profile

S: 27    gitvvinaslsvikvqviPeylikkgityknipvdDsdvtdllqyfdeaaefideakekg  86

         g+ + ++ ++   k +  Pe +   +i   + +v D+d   ++++  +++ f++++k+++

Q: 88    GLIIDLTYTHRYYKPEDLPETIPYLKIYTIGHQVPDDD--TIFKFKCAVNGFLKDNKDND  145

         55566677777777777777776666666666666665..59******************

S: 87    gkvlvHCaaGvsRSatlvlaYLmkveglslsdAieavkrkrpsiepnegfleQLl  141

         + + vHC++G++R+++l++ YL++veg++ + Aie ++r+r+++ ++++++e L

Q: 146   KLIGVHCTHGLNRTGYLICRYLIDVEGMRPDAAIELFNRCRGHCLERQNYIEDLQ  200

         ***************************************************9986

Domain Sequence
(FASTA)

GLIIDLTYTH RYYKPEDLPE TIPYLKIYTI GHQVPDDDTI FKFKCAVNGF LKDNKDNDKL 60

IGVHCTHGLN RTGYLICRYL IDVEGMRPDA AIELFNRCRG HCLERQNYIE DLQ 113

Keyword

Complete proteome; Hydrolase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Taeniopygia guttata"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0004725	; F:protein tyrosine phosphatase activity
GO:0008138	; F:protein tyrosine/serine/threonine phosphatase activity
GO:0035335	; P:peptidyl-tyrosine dephosphorylation

KEGG

InterPros

IPR000340	; Dual-sp_phosphatase_cat-dom.
IPR000387	; Tyr/Dual-specificity_Pase.
IPR016130	; Tyr_Pase_AS.

Pfam

PF00782

; DSPc; 1.

SMARTs

Prosites

PS00383	; TYR_PHOSPHATASE_1; 1.
PS50056	; TYR_PHOSPHATASE_2; 1.

Prints

Created Date

20-Feb-2013