EKS-EQC-00185

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-EQC-00185

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/NKF5	526.1	1.5E-158	272	519	248

Status

Unreviewed

Ensembl Protein

ENSECAP00000021116

UniProt Accession

F7C8B0;

Protein Name

Protein Synonyms/Alias

Gene Name

TEX14

Gene Synonyms/Alias

TEX14;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSECAG00000023617	ENSECAP00000021116	ENSECAT00000025388

Organism

Equus caballus

Functional Description

Protein Length

1498

Protein Sequence
(FASTA)

MSRAVPLPVP CPVQLGSLRN DSLEAQLHEY VKQGNYVKVK KILKKGIYVD AVNSLGQTAL 60

FVAALLGLTK LVDVLVDYGS DPNHRCFDGS TPVHAAAFSG NQWILSKLLD AGGDLRLHDE 120

KGRNPKTWAL TAGKERSTVM VEFMQRCASH MQAIIQGFSQ DLLKKIDSPQ RLICGLPRFG 180

GLMQGSPNGS PNRLLKAGVV SAQNIYSFGF GKVRAVFCFQ FYITGGTQLA YLGSLPVIGE 240

KEVIQADDEP TFSFFSGPYM VMINLVWNGS RVTVKELNLP THPHCSRLRL ADLLIAEQEH 300

SSKLRHPHLL QLMAVCLSQD LEKTRLVYER ITVGTLFSVL HERRSQFPVL HMEVIVHLLL 360

QISDALRYLH SRGFIHRSLS SYAVHIVSTG EARLTNLEYM MESQDGGVHR DLTRVPLPTQ 420

LYNWAAPEVI LQKAATVKSD IYSFSVIIQE ILTDNIPWNG LDGSVIKDAI VLGKYLEADV 480

RLPKPYYDIV KSGIQVKQKD RTMNLQDIRY ILKNDLKDFI GAQRTQPTVS PRVQRYELHP 540

DVNVYLGLTS EHPKETSDLE IKELKEMGMA LTHRMILQAL VTFGALSHVA PEGERMAQKD 600

WAGFCSAPSG LVVNFAHSAS VAQGSLVQIS AADLHTAHQA MLWHQLHSPR GRSSPTEKAA 660

PDPQVPDSSL MAKETQNQET ASPACSVDES SSEADTELSF EDLDWQNGSL SSLSLPEPAR 720

EAEGNVSNRS MTEEYISKCV LNLKISQMLM HQNADLLRNT QQKIDKLEMI QKEQEERKSL 780

WASSREFANV CDLPSALGPP ALSYVPPVMQ LSGGQQPDTG GNCLTLARSS RTLPTLCGPG 840

KQSRSEQVQP PQGAKDSLER NRNQNINSQG RPSEASAQAK VSQLSSVLFT TSSRQQGPPM 900

SSSPGQGSAI SMESVSSEIC NAKSRNNEDS GEVHLKWKTE VKEIAEKAAT GQLAVPPWHP 960

RSGLTLENEA GNEPDPLLQP PIMEPENVDW QQVAEYPRKN DEPGGSVKFD KTGHSDHDSD 1020

QHGRQSGPRS FTGIRHPSLR KNEQPEHSEV FQASSDASVV IEKSYSDQSV QSTCSPESSE 1080

DITDEFLTPE YDYFYSSAAQ ENLALETSSP IEEGFEGIQD AFAQPQASGE EKFQVRKSLG 1140

KNAEVLTKSH FQPVRSTAGE QEETLKESPV EVKEKDISLT DIQDLSSISY EQDGSFKEVS 1200

CKTPRINHAP TSVSTPLSPG SISSAASRYK DCLESITFQV KTGSTSCWNS QESIPTLCDT 1260

FTTVRERAKS LDSLLTSSET LRSRLTDLKK LSTFTGAGSS SIAKAPDTSS HAMQRRSLPK 1320

VETISQHNID ELPPPSQELL DEIEHLKQQQ ASSTVLDEST ASHLGITAND QRHLEEQETI 1380

SKKEDNMLWT KETQDLEEDT ERAHSTLDED LERWLQQPED SMELQDLPKG SAREMNTKDQ 1440

EVGKKKRKGE ESTKPERRKS ESFLGTSEEE ELKPCIWKRL GWSEPSRIIV LDQSDSSD 1498

Nucleotide Sequence
(FASTA)

ATGTCTCGTG CTGTTCCTCT TCCAGTCCCC TGTCCAGTTC AGCTTGGTTC CTTAAGAAAT 60

GATTCCTTGG AAGCTCAGCT TCATGAGTAT GTCAAACAAG GGAACTATGT GAAAGTGAAG 120

AAGATTCTTA AGAAAGGAAT TTATGTTGAT GCAGTCAACT CCCTGGGCCA GACAGCTCTT 180

TTTGTTGCAG CATTATTAGG CCTTACAAAA TTAGTTGATG TTCTGGTGGA TTATGGATCA 240

GATCCAAATC ACCGCTGCTT TGATGGGAGC ACCCCTGTCC ACGCAGCAGC ATTTTCCGGC 300

AACCAGTGGA TCCTCAGCAA ACTGCTAGAT GCAGGGGGTG ACCTTCGACT CCATGACGAG 360

AAGGGTCGAA ACCCGAAGAC CTGGGCCCTG ACAGCAGGGA AGGAGCGCAG CACTGTGATG 420

GTGGAGTTCA TGCAGCGCTG TGCCTCACAC ATGCAGGCCA TCATCCAGGG CTTCTCCCAG 480

GACCTCCTGA AGAAGATTGA CTCCCCTCAG CGCCTCATCT GTGGCCTGCC CCGGTTTGGG 540

GGCCTCATGC AGGGAAGCCC TAATGGCTCT CCTAACCGAC TGCTTAAAGC TGGAGTCGTT 600

TCTGCCCAAA ATATCTACAG CTTTGGCTTT GGGAAGGTAA GAGCTGTGTT TTGCTTTCAG 660

TTTTATATCA CAGGGGGGAC ACAGCTGGCC TACCTAGGAT CTCTTCCAGT CATTGGAGAA 720

AAGGAAGTGA TTCAAGCTGA TGATGAGCCC ACCTTCTCTT TCTTCAGTGG CCCCTACATG 780

GTCATGATCA ACCTGGTGTG GAACGGGAGC AGGGTCACAG TGAAGGAGCT GAATCTCCCC 840

ACCCACCCAC ATTGCAGCAG GCTGCGGCTG GCTGACTTGT TAATTGCTGA GCAGGAGCAC 900

AGCAGCAAGC TGCGGCACCC CCACCTGCTG CAGCTGATGG CTGTGTGCCT GTCCCAGGAC 960

CTGGAGAAGA CCCGCCTCGT GTACGAGCGC ATTACTGTCG GCACGCTGTT CAGTGTCCTC 1020

CATGAACGGC GCTCTCAGTT CCCGGTGCTG CACATGGAGG TGATTGTACA CCTGCTGCTC 1080

CAGATTTCCG ATGCTCTGAG ATACCTGCAT TCCCGAGGCT TTATCCACCG CTCCCTCAGC 1140

TCCTACGCTG TCCACATCGT CTCCACAGGG GAAGCGAGGC TGACCAACCT GGAGTACATG 1200

ATGGAAAGCC AGGATGGAGG TGTCCATAGG GACCTGACTC GAGTGCCCCT CCCCACCCAG 1260

CTGTATAACT GGGCGGCCCC GGAGGTGATC CTACAGAAGG CAGCCACGGT GAAGTCGGAC 1320

ATCTACAGCT TTTCTGTGAT CATACAGGAG ATTTTAACAG ATAACATACC TTGGAATGGC 1380

TTAGATGGCT CAGTTATTAA AGATGCTATA GTCTTGGGAA AGTATTTAGA AGCTGATGTC 1440

AGGCTTCCAA AACCTTATTA CGATATTGTT AAGTCAGGCA TCCAGGTCAA GCAGAAGGAC 1500

CGAACTATGA ACCTTCAGGA CATCCGGTAT ATTCTGAAGA ATGACTTAAA GGATTTTATT 1560

GGAGCCCAGA GAACTCAGCC AACCGTGAGC CCCAGGGTTC AGAGATATGA ACTCCATCCT 1620

GATGTTAATG TCTATCTAGG ACTGACTTCA GAACATCCAA AAGAGACCTC TGACTTGGAA 1680

ATAAAAGAGC TGAAGGAAAT GGGTATGGCT TTAACCCACA GAATGATCCT CCAAGCTCTC 1740

GTTACTTTTG GAGCATTGTC TCATGTAGCG CCAGAAGGTG AGAGAATGGC ACAAAAAGAC 1800

TGGGCAGGAT TCTGCTCTGC TCCCAGTGGC CTAGTGGTTA ATTTTGCGCA CTCTGCTTCA 1860

GTAGCCCAGG GTTCACTGGT TCAGATCTCA GCCGCAGACC TACACACTGC TCATCAAGCC 1920

ATGCTGTGGC ATCAGCTTCA TTCACCAAGG GGTCGCTCTT CTCCCACCGA GAAAGCAGCA 1980

CCAGATCCTC AGGTTCCAGA TTCAAGTCTG ATGGCCAAGG AGACGCAGAA CCAAGAGACT 2040

GCTTCTCCTG CTTGTTCTGT GGATGAGAGC TCTTCAGAAG CTGACACAGA GCTCTCCTTT 2100

GAGGACTTAG ACTGGCAAAA TGGTTCTCTT AGTTCCCTCA GCCTACCTGA GCCAGCCAGA 2160

GAAGCCGAGG GCAATGTGAG CAACAGGTCC ATGACTGAGG AGTACATCAG TAAGTGTGTG 2220

CTGAATCTAA AGATTTCACA GATGTTAATG CACCAGAATG CTGATTTGCT AAGGAATACC 2280

CAACAGAAAA TAGATAAGCT TGAGATGATA CAGAAGGAGC AGGAGGAGCG CAAGTCTCTG 2340

TGGGCCTCTT CAAGAGAGTT TGCAAACGTC TGTGACTTGC CTTCAGCCCT GGGCCCCCCA 2400

GCTTTAAGCT ATGTTCCTCC TGTCATGCAG CTGTCAGGGG GCCAGCAGCC AGACACTGGT 2460

GGCAATTGCT TGACTTTAGC AAGGTCTTCA AGAACACTGC CAACTCTTTG TGGCCCTGGA 2520

AAACAGAGCA GAAGTGAACA AGTTCAGCCC CCTCAAGGAG CGAAGGACAG TTTGGAAAGA 2580

AATAGGAACC AAAATATCAA CAGCCAGGGA AGGCCTAGTG AGGCCAGTGC CCAAGCCAAA 2640

GTGTCACAGC TAAGTAGTGT ACTCTTCACC ACGTCAAGCC GCCAGCAGGG ACCTCCCATG 2700

TCATCCAGCC CTGGCCAGGG CTCTGCGATC AGTATGGAAT CTGTGTCTTC TGAAATCTGT 2760

AATGCAAAGT CAAGAAATAA TGAAGATAGT GGAGAGGTAC ACTTAAAATG GAAAACGGAG 2820

GTGAAAGAAA TAGCAGAGAA AGCAGCTACT GGGCAGCTGG CAGTACCTCC TTGGCATCCT 2880

CGGAGTGGTT TGACTTTAGA GAATGAGGCT GGAAATGAGC CTGATCCCCT GCTGCAGCCC 2940

CCCATTATGG AACCTGAGAA TGTGGACTGG CAGCAAGTTG CAGAGTATCC CAGGAAAAAT 3000

GATGAGCCAG GAGGAAGTGT CAAGTTTGAC AAAACAGGCC ACAGTGACCA TGACAGTGAC 3060

CAGCATGGCA GACAGTCTGG GCCTCGAAGC TTCACTGGTA TCAGGCACCC GTCCCTCAGG 3120

AAAAATGAGC AGCCAGAGCA TAGTGAAGTC TTTCAAGCAA GTTCTGATGC ATCTGTGGTC 3180

ATTGAGAAAT CTTACAGCGA TCAGTCTGTG CAATCAACTT GTTCACCAGA GTCTTCTGAG 3240

GACATAACAG ATGAATTTTT AACTCCAGAA TATGACTATT TTTACTCCTC GGCAGCTCAA 3300

GAAAACTTAG CTCTAGAGAC CTCAAGTCCC ATAGAAGAGG GCTTTGAAGG AATACAAGAT 3360

GCGTTTGCCC AACCGCAAGC TTCTGGTGAA GAAAAGTTCC AAGTGAGAAA AAGCCTTGGA 3420

AAGAATGCTG AGGTTTTGAC TAAGTCTCAT TTCCAACCTG TACGGAGTAC TGCAGGTGAA 3480

CAAGAGGAGA CATTAAAGGA GTCACCAGTG GAAGTGAAAG AGAAAGACAT ATCATTGACA 3540

GACATTCAAG ACCTGTCTAG TATCTCATAT GAGCAGGACG GTTCTTTTAA GGAAGTCTCA 3600

TGCAAAACAC CCAGAATAAA CCATGCACCT ACTAGTGTCA GCACTCCACT CAGCCCAGGG 3660

TCAATTTCTT CAGCTGCCAG TCGGTATAAA GACTGCCTTG AAAGTATCAC ATTTCAAGTT 3720

AAAACAGGGT CTACCTCATG CTGGAACAGT CAAGAATCTA TCCCAACTTT GTGTGATACA 3780

TTTACAACTG TCCGGGAGAG AGCAAAGAGC CTAGATTCCC TTCTTACTTC CTCTGAAACT 3840

CTCCGTTCAA GATTGACTGA TCTCAAAAAG TTGTCTACAT TTACTGGGGC TGGTTCCTCC 3900

AGCATTGCTA AGGCACCGGA CACATCATCC CATGCCATGC AGAGAAGGAG TCTGCCAAAA 3960

GTAGAAACCA TCTCACAGCA TAACATTGAT GAGCTACCAC CACCATCTCA GGAGCTACTT 4020

GACGAAATTG AGCACTTGAA GCAGCAGCAG GCCTCATCCA CAGTGTTGGA TGAGAGCACA 4080

GCAAGTCACC TGGGCATCAC TGCAAATGAT CAAAGGCACT TAGAAGAGCA AGAAACTATC 4140

AGTAAAAAAG AAGATAATAT GCTTTGGACC AAAGAAACTC AGGATCTAGA AGAGGACACA 4200

GAGAGAGCTC ACTCTACTCT GGATGAGGAC CTGGAAAGAT GGCTGCAGCA ACCTGAGGAC 4260

AGCATGGAGC TACAGGATCT CCCCAAGGGC TCTGCAAGGG AGATGAATAC CAAGGATCAA 4320

GAAGTTGGTA AAAAGAAGAG AAAAGGGGAA GAAAGCACCA AGCCAGAGAG AAGGAAGTCA 4380

GAGAGCTTTT TAGGGACTTC TGAAGAAGAG GAACTTAAAC CCTGTATTTG GAAGCGACTG 4440

GGTTGGTCTG AACCATCCAG GATAATTGTG CTGGATCAGA GTGACTCATC AGACTGA 4497

Domain Profile

S: 1     vtvkelnlpthphcsrlrladlliaeqehssklrhpyllqllavclsqdlektrlvyeri  60

         vtvkelnlpthphcsrlrladlliaeqehssklrhp+llql+avclsqdlektrlvyeri

Q: 272   VTVKELNLPTHPHCSRLRLADLLIAEQEHSSKLRHPHLLQLMAVCLSQDLEKTRLVYERI  331

         79**********************************************************

S: 61    tigtlfsvlherrsqfpvlhmevivhlllqisdalrylhfrgfihrslssyavhiisage  120

         t+gtlfsvlherrsqfpvlhmevivhlllqisdalrylh+rgfihrslssyavhi+s+ge

Q: 332   TVGTLFSVLHERRSQFPVLHMEVIVHLLLQISDALRYLHSRGFIHRSLSSYAVHIVSTGE  391

         ************************************************************

S: 121   arltnleyllesedrgvqrdltrvplptqlynwaapevilqkaatvksdiysfsiiiqei  180

         arltnley++es+d gv+rdltrvplptqlynwaapevilqkaatvksdiysfs+iiqei

Q: 392   ARLTNLEYMMESQDGGVHRDLTRVPLPTQLYNWAAPEVILQKAATVKSDIYSFSVIIQEI  451

         ************************************************************

S: 181   ltdeiPWkGldGsvvkkavvaGnyleadvrlPkPyydivksGihvkqkdrtmnlqdiryi  240

         ltd+iPW+GldGsv+k+a+v+G+yleadvrlPkPyydivksGi+vkqkdrtmnlqdiryi

Q: 452   LTDNIPWNGLDGSVIKDAIVLGKYLEADVRLPKPYYDIVKSGIQVKQKDRTMNLQDIRYI  511

         ************************************************************

S: 241   lkndlkdf  248

         lkndlkdf

Q: 512   LKNDLKDF  519

         *******9

Domain Sequence
(FASTA)

VTVKELNLPT HPHCSRLRLA DLLIAEQEHS SKLRHPHLLQ LMAVCLSQDL EKTRLVYERI 60

TVGTLFSVLH ERRSQFPVLH MEVIVHLLLQ ISDALRYLHS RGFIHRSLSS YAVHIVSTGE 120

ARLTNLEYMM ESQDGGVHRD LTRVPLPTQL YNWAAPEVIL QKAATVKSDI YSFSVIIQEI 180

LTDNIPWNGL DGSVIKDAIV LGKYLEADVR LPKPYYDIVK SGIQVKQKDR TMNLQDIRYI 240

LKNDLKDF 248

Keyword

ANK repeat; Complete proteome; Reference proteome; Repeat.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Felis catus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Xenopus tropicalis"; ?>

Gene Ontology

GO:0045171	; C:intercellular bridge
GO:0000776	; C:kinetochore
GO:0030496	; C:midbody
GO:0005524	; F:ATP binding
GO:0004672	; F:protein kinase activity
GO:0008608	; P:attachment of spindle microtubules to kinetochore
GO:0043063	; P:intercellular bridge organization
GO:0007140	; P:male meiosis
GO:0007094	; P:mitotic cell cycle spindle assembly checkpoint
GO:0051306	; P:mitotic sister chromatid separation
GO:0032466	; P:negative regulation of cytokinesis
GO:0032091	; P:negative regulation of protein binding

KEGG

InterPros

IPR002110	; Ankyrin_rpt.
IPR020683	; Ankyrin_rpt-contain_dom.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR001245	; Ser-Thr/Tyr_kinase_cat_dom.

Pfam

PF12796	; Ank_2; 1.
PF07714	; Pkinase_Tyr; 1.

SMARTs

SM00248

; ANK; 3.

Prosites

PS50297	; ANK_REP_REGION; 1.
PS50088	; ANK_REPEAT; 2.
PS50011	; PROTEIN_KINASE_DOM; 1.

Prints

Created Date

20-Feb-2013