EKS-ERE-00006

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ERE-00006

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/IRAK	332.0	2.1E-99	2	271	270

Status

Unreviewed

Ensembl Protein

ENSEEUP00000011117

Gene Name

IRAK1

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSEEUG00000012190	ENSEEUP00000011117	ENSEEUT00000012188

Organism

Erinaceus europaeus

Protein Length

457

Protein Sequence
(FASTA)

ADLEWSTVRQ SFLTEVEQLS RFRHPNIVDF AGYCAQSGFY CLVYGFLPSG SLEDRLHLQS 60

QAHGPLSWSQ RLHVLVGTAR ALQFLHQDSP SLIHGDVKSS NILLDEQLLP KLGDFGLARL 120

SRFSGATPGQ SSTVARTRSV RGTLAYLPED YVKTGRLAVD TDTFSFGVVV LECLAGQRAV 180

LTQGTKTKYL KDLVEEEAEE AGLTLKSTQQ AGMAADGWAA PIAARICQKH VDPRPGPCPR 240

ELGLPLAQLL CCCLQRRAKK RPPMTQVYAR LEQLQAALMG PSQEPEAALR GPPSPQENSY 300

VSAASCAPNT ASPQQPLTVP SEVPTTARLQ KGPNQPEESD ESLPGLFTAL RSWRLGPSRT 360

PTPPARQPGT SPWAPAPLGP ASHEPGALHA VEGSLPGSPS APRIVINPAR RKMLQKLALY 420

EDGVLDSLQL LSSSSLPDLG LEREGRQRPE ESDEFQS 457

Nucleotide Sequence
(FASTA)

GCAGACCTGG AGTGGAGCAC TGTGCGGCAG AGCTTCCTAA CAGAGGTGGA ACAGCTGTCG 60

AGGTTCCGAC ACCCCAACAT CGTGGACTTT GCTGGCTACT GTGCTCAGAG TGGCTTCTAC 120

TGCCTGGTCT ATGGCTTCCT GCCCAGCGGC TCCCTGGAAG ACCGCCTGCA CCTCCAGTCC 180

CAGGCCCATG GCCCTCTGTC CTGGTCGCAG CGGCTGCACG TGCTTGTGGG CACCGCCCGG 240

GCCCTCCAGT TCCTCCATCA GGACAGCCCC AGCCTCATCC ACGGAGATGT CAAGAGTTCC 300

AACATTCTTC TGGATGAGCA GCTGCTGCCC AAGCTGGGGG ACTTCGGCCT GGCCCGCCTG 360

AGCCGCTTCT CGGGGGCCAC CCCCGGCCAG AGCAGCACTG TGGCGCGGAC CCGCTCAGTG 420

CGAGGCACCC TGGCCTACCT GCCCGAGGAC TATGTGAAGA CGGGGCGGCT GGCTGTGGAC 480

ACAGACACCT TCAGCTTTGG CGTGGTGGTG CTGGAGTGCC TGGCTGGCCA GAGGGCAGTG 540

CTGACACAGG GCACCAAGAC CAAGTACCTG AAGGACCTGG TTGAGGAGGA AGCCGAGGAG 600

GCCGGGCTGA CCCTGAAAAG CACACAGCAG GCAGGCATGG CCGCAGATGG CTGGGCCGCC 660

CCCATCGCTG CCCGAATCTG CCAGAAGCAC GTGGACCCTA GGCCCGGGCC GTGCCCCCGC 720

GAGTTAGGCC TGCCACTGGC CCAGCTGCTG TGCTGCTGCC TGCAGCGCCG GGCCAAGAAG 780

AGACCGCCCA TGACGCAGGT GTACGCGAGG CTGGAGCAGC TGCAGGCAGC CCTGATGGGC 840

CCGTCCCAGG AGCCAGAGGC AGCCCTCAGA GGGCCCCCGT CCCCACAGGA GAACTCCTAT 900

GTGTCTGCCG CGAGCTGTGC CCCGAACACT GCCAGCCCAC AGCAGCCCCT GACTGTGCCC 960

TCAGAGGTCC CGACCACAGC GCGGCTCCAG AAAGGCCCCA ACCAGCCAGA GGAGAGCGAC 1020

GAGAGCCTAC CCGGCCTGTT CACAGCCCTG CGCTCCTGGC GGCTGGGTCC CAGCCGCACC 1080

CCTACCCCTC CTGCCAGGCA GCCCGGCACC TCGCCGTGGG CCCCGGCACC CCTCGGGCCA 1140

GCCAGCCATG AGCCAGGAGC GCTGCACGCT GTGGAAGGCT CCCTCCCGGG CAGTCCCTCG 1200

GCCCCACGCA TCGTCATCAA CCCGGCGCGG CGGAAGATGC TGCAGAAGCT GGCCCTGTAT 1260

GAGGACGGGG TCCTGGACAG CCTGCAGCTG CTCTCATCCA GCTCCCTGCC AGATCTGGGC 1320

CTGGAGCGTG AGGGCAGACA GCGGCCCGAG GAGAGCGATG AGTTTCAGAG CTGA 1374

Domain Profile

S: 35    dlslkelkqsfltElkvlarfrHdnilellgysaeseklcLvYqymknGsLedrLqcq.k  93

         dl++++++qsfltE+++l+rfrH+ni++++gy+a+s+++cLvY++++ GsLedrL+ q +

Q: 2     DLEWSTVRQSFLTEVEQLSRFRHPNIVDFAGYCAQSGFYCLVYGFLPSGSLEDRLHLQsQ  61

         7899******************************************************99

S: 94    gsepLsWpqRlsillGtaraiefLHeaspslihgdiksaNiLLDekltpKlgDfglar..  151

         +  pLsW qRl++l+Gtara++fLH++spslihgd+ks+NiLLDe+l pKlgDfglar

Q: 62    AHGPLSWSQRLHVLVGTARALQFLHQDSPSLIHGDVKSSNILLDEQLLPKLGDFGLARls  121

         99*******************************************************999

S: 152   .fapesekqsstvlrtskvrgtlaYlpeefirvgqltvkvDvySfGiVllEvltGlra.v  209

          f ++++ qsstv+rt +vrgtlaYlpe+++++g+l+v++D++SfG+V+lE l+G+ra

Q: 122   rFSGATPGQSSTVARTRSVRGTLAYLPEDYVKTGRLAVDTDTFSFGVVVLECLAGQRAvL  181

         999*******************************************************78

S: 210   dedrktkyLkdllkeeieeekv.....................eilekfldkkagkleee  248

         +++ ktkyLkdl++ee+ee+++                      i++k++d ++g++++e

Q: 182   TQGTKTKYLKDLVEEEAEEAGLtlkstqqagmaadgwaapiaaRICQKHVDPRPGPCPRE  241

         999*********************************************************

S: 249   llealielalaclaekakkrPtmsqvlell  278

         l   l++l ++cl+++akkrP+m+qv+ +l

Q: 242   LGLPLAQLLCCCLQRRAKKRPPMTQVYARL  271

         **************************9886

Domain Sequence
(FASTA)

DLEWSTVRQS FLTEVEQLSR FRHPNIVDFA GYCAQSGFYC LVYGFLPSGS LEDRLHLQSQ 60

AHGPLSWSQR LHVLVGTARA LQFLHQDSPS LIHGDVKSSN ILLDEQLLPK LGDFGLARLS 120

RFSGATPGQS STVARTRSVR GTLAYLPEDY VKTGRLAVDT DTFSFGVVVL ECLAGQRAVL 180

TQGTKTKYLK DLVEEEAEEA GLTLKSTQQA GMAADGWAAP IAARICQKHV DPRPGPCPRE 240

LGLPLAQLLC CCLQRRAKKR PPMTQVYARL 270

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dasypus novemcinctus"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>