EKS-ERE-00020

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ERE-00020

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/DYRK	369.8	8.7E-111	11	346	336

Status

Unreviewed

Ensembl Protein

ENSEEUP00000013477

Gene Name

HIPK4

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSEEUG00000014774	ENSEEUP00000013477	ENSEEUT00000014770

Organism

Erinaceus europaeus

Protein Length

606

Protein Sequence
(FASTA)

MATIQSETDC YDIIEVLGKG TFGEVAKGWR RSTGEMVAIK ILKNDAYNRI IKNELKLLRC 60

MRGLDPEEAH VIRFLEFFHD ALKFYLVFEL LEQNLFEFQK ENNFAPLPAR HIRTVTLQVL 120

RALARLKELA IIHADLKPEN IMLVDQTRCP FRVKVIDFGS ASIFSEVRYV KEPYIQSRFY 180

RAPEILLGLP FCEKVDVWSL GCVMAELHLG WPLYPGNNEY DQVRYICETQ GLPKPHLLHA 240

ARKAHHFFKR SPHPDTTSPW QLKSSADYLA ETKVRPLERR KYMLKSLDQI ETVNGGGAAG 300

RLPFPDREAL AEHADLKSMV ELIKRMLTWE SHERISPSAA LRHPFVSMQQ LRSAHEATRY 360

YQLSLRSCRL SLQVQGKAGA PAVAAAADGS PYYRLAEEEE ARAAPLFRDD KVPGVQRAID 420

QLDDLSLQEA GRGLWGEALP DGVPDVLAPL GAAHHAADAA PEPILAFYGS RLAGRKARKP 480

PAGCKSDSNF SNLIRLSQAS PDDAGTCRGS GWAEGEPRGA SAEPPAIPQR DGDGPSVKNM 540

IMDTERPDPE LFDPSSCPGE WLSEPDWTLE GLRGPRTQGL TPRHVHVHPH GPPRAANFLQ 600

HVSGHH 606

Nucleotide Sequence
(FASTA)

ATGGCCACCA TCCAGTCGGA GACTGACTGC TATGACATCA TCGAGGTGCT GGGCAAGGGC 60

ACCTTTGGGG AGGTGGCCAA GGGCTGGCGG CGGAGCACGG GTGAGATGGT GGCCATCAAG 120

ATCCTGAAGA ATGACGCCTA CAACCGTATC ATCAAGAACG AGCTGAAGCT GCTGCGCTGC 180

ATGCGGGGGC TGGACCCTGA GGAGGCCCAT GTCATCCGCT TTCTTGAATT CTTCCACGAC 240

GCCCTCAAGT TCTACCTAGT CTTCGAGCTG CTGGAGCAAA ACCTCTTTGA GTTCCAGAAA 300

GAGAACAACT TCGCGCCCCT GCCAGCCCGC CACATCCGCA CGGTCACACT GCAGGTGCTC 360

AGAGCCCTGG CCCGGCTCAA GGAGCTGGCC ATCATCCATG CCGATCTCAA GCCCGAGAAC 420

ATCATGCTGG TGGACCAGAC CCGCTGCCCT TTCCGGGTCA AGGTGATCGA CTTCGGCTCT 480

GCCAGCATCT TCAGCGAGGT GCGCTATGTG AAGGAACCCT ACATCCAGTC TCGCTTCTAC 540

CGGGCCCCCG AGATCCTGCT GGGGCTGCCC TTCTGCGAGA AGGTGGACGT GTGGTCGCTG 600

GGCTGTGTCA TGGCCGAGCT GCACCTGGGC TGGCCCCTCT ACCCCGGCAA CAATGAGTAT 660

GACCAGGTGC GCTACATCTG CGAGACGCAG GGCCTGCCCA AGCCCCACCT GCTGCACGCC 720

GCACGCAAGG CCCACCATTT CTTCAAGCGC AGCCCCCACC CCGACACCAC CAGCCCCTGG 780

CAGCTCAAGT CCTCGGCTGA CTACCTGGCA GAGACCAAGG TGCGCCCCCT GGAGCGCCGG 840

AAGTACATGC TCAAGTCGCT GGACCAGATC GAGACGGTGA ACGGCGGCGG CGCGGCCGGC 900

CGGCTGCCCT TCCCGGACCG CGAGGCGCTG GCGGAGCACG CCGACCTCAA GAGCATGGTG 960

GAGCTCATCA AGCGCATGCT CACGTGGGAG TCGCACGAGC GCATCAGCCC GAGCGCCGCG 1020

CTGCGCCACC CCTTCGTGTC CATGCAGCAG CTCCGCAGCG CGCACGAAGC CACGCGATAT 1080

TACCAGCTCT CGCTGCGCAG CTGCCGCCTG TCGCTGCAGG TGCAGGGCAA GGCCGGCGCG 1140

CCCGCCGTGG CCGCCGCCGC CGACGGGTCC CCGTACTACC GCCTGGCTGA GGAGGAGGAG 1200

GCGCGGGCGG CGCCCCTCTT CCGCGACGAC AAGGTGCCCG GCGTGCAGCG GGCCATCGAC 1260

CAGCTAGACG ACCTGAGCCT GCAGGAGGCG GGCCGCGGGC TGTGGGGCGA GGCGCTCCCC 1320

GACGGGGTCC CCGACGTGCT GGCGCCGCTC GGCGCCGCCC ACCACGCGGC CGACGCGGCC 1380

CCCGAGCCCA TCCTCGCCTT CTACGGTAGC CGCCTGGCCG GCCGCAAGGC CCGCAAGCCT 1440

CCCGCCGGTT GCAAGTCGGA CTCCAACTTC AGCAACCTCA TCCGGCTGAG CCAGGCCTCG 1500

CCCGACGACG CGGGAACCTG CAGGGGCAGC GGCTGGGCCG AGGGGGAGCC CCGCGGGGCC 1560

TCCGCAGAGC CGCCCGCCAT CCCGCAGCGC GACGGGGATG GCCCCAGCGT CAAGAACATG 1620

ATCATGGACA CGGAGAGGCC GGACCCTGAG CTCTTTGACC CCAGCAGCTG TCCTGGGGAA 1680

TGGCTGAGCG AGCCAGACTG GACCCTGGAG GGCCTCCGGG GGCCACGCAC CCAGGGTCTC 1740

ACGCCCCGTC ACGTGCATGT GCACCCACAT GGCCCACCCC GGGCCGCCAA CTTTCTGCAG 1800

CACGTCAGCG GACACCACTG A 1821

Domain Profile

S: 1     yevlevigkGsfgqVvkaldkktkeivaikiiknkkrfarqaqeEveiLeklnkkdkeek  60

         y+++ev+gkG+fg+V+k+++++t e+vaiki+kn+ +++r +++E+++L++++  d+ee+

Q: 11    YDIIEVLGKGTFGEVAKGWRRSTGEMVAIKILKND-AYNRIIKNELKLLRCMRGLDPEEA  69

         99******************************986.6899*****************988

S: 61    ynvvrllelfvfrnhlclvfellsqnLyellkknkfsglslklvrklaqqilkaLklLke  120

          +v+r+le+f+   +++lvfell+qnL+e+ k+n+f++l+ +++r+++ q+l+aL+ Lke

Q: 70    -HVIRFLEFFHDALKFYLVFELLEQNLFEFQKENNFAPLPARHIRTVTLQVLRALARLKE  128

         .9**********************************************************

S: 121   lkiiHaDlKPeNillvekkrse..vkviDFGsssavsqk..eiytyiqsrfYraPEiilg  176

         l+iiHaDlKPeNi+lv+++r++  vkviDFGs+s +s+   + ++yiqsrfYraPEi+lg

Q: 129   LAIIHADLKPENIMLVDQTRCPfrVKVIDFGSASIFSEVryVKEPYIQSRFYRAPEILLG  188

         *********************999**********99987447899***************

S: 177   lkydeaiDmWSlGcvlaElftGkpLfpGenevdqlalivevlglppekllekakkakkff  236

         l+++e++D+WSlGcv+aEl++G+pL+pG+ne+dq+++i+e++glp+++ll++a+ka++ff

Q: 189   LPFCEKVDVWSLGCVMAELHLGWPLYPGNNEYDQVRYICETQGLPKPHLLHAARKAHHFF  248

         ************************************************************

S: 237   tkkeapkyilktk.............ksdrkkklvlnvkkaakkrkaplsk.....elge  278

         +++ +p  +  ++                +++k++l+  +++++++  +++       +e

Q: 249   KRSPHPDTTSPWQlkssadylaetkvRPLERRKYMLKSLDQIETVNGGGAAgrlpfPDRE  308

         888888777666667779999988886667778888888888877765554111224578

S: 279   alkekedkl.fkdllkrmleldpakRitpkealkhpfv  315

         al+e++d + +++l+krml++++++Ri+p++al+hpfv

Q: 309   ALAEHADLKsMVELIKRMLTWESHERISPSAALRHPFV  346

         8888888888***************************7

Domain Sequence
(FASTA)

YDIIEVLGKG TFGEVAKGWR RSTGEMVAIK ILKNDAYNRI IKNELKLLRC MRGLDPEEAH 60

VIRFLEFFHD ALKFYLVFEL LEQNLFEFQK ENNFAPLPAR HIRTVTLQVL RALARLKELA 120

IIHADLKPEN IMLVDQTRCP FRVKVIDFGS ASIFSEVRYV KEPYIQSRFY RAPEILLGLP 180

FCEKVDVWSL GCVMAELHLG WPLYPGNNEY DQVRYICETQ GLPKPHLLHA ARKAHHFFKR 240

SPHPDTTSPW QLKSSADYLA ETKVRPLERR KYMLKSLDQI ETVNGGGAAG RLPFPDREAL 300

AEHADLKSMV ELIKRMLTWE SHERISPSAA LRHPFV 336

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Dasypus novemcinctus"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>