EKS-ECT-00043

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ECT-00043

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	234.8	9.5E-70	9	241	233

Status

Unreviewed

Ensembl Protein

ENSETEP00000015329

Gene Name

CDK4

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSETEG00000018867	ENSETEP00000015329	ENSETET00000018866

Organism

Echinops telfairi

Protein Length

246

Protein Sequence
(FASTA)

MATSRYEPVA ENCVGTYGTV YKAREPHSGH FVARKSVRVP NGEGTGCGLP ISTVREVALL 60

RRLEAFDHPS VVRLMDVCAT ARTDWETKVT LVLEHVDQDL RTYLDKAPSP GLPVEIIKDL 120

MRQFLRGLDF LHANCIVHRD LKPENILMTS NGTVKLADGL ARIYSYQMAL TPVVVALWYR 180

APEVLVQSAY ATPVDMWSVG CIFPEMFRRF CGNSDADLLG NIFLIGLPPE DDWSRDVSLP 240

QGAFPS 246

Nucleotide Sequence
(FASTA)

ATGGCTACCT CTCGCTATGA GCCAGTGGCC GAGAATTGTG TGGGCACCTA TGGCACGGTG 60

TACAAGGCCC GTGAGCCCCA CAGTGGCCAC TTTGTGGCCC GCAAGAGTGT GAGAGTCCCC 120

AATGGAGAAG GCACTGGCTG CGGCCTTCCT ATCAGCACTG TTCGGGAGGT GGCCCTACTG 180

AGACGGCTGG AGGCGTTCGA CCATCCCAGT GTTGTCCGGC TGATGGACGT CTGTGCCACA 240

GCCCGAACTG ACTGGGAAAC CAAGGTGACG CTGGTGCTTG AACATGTGGA CCAAGACCTA 300

AGGACGTACT TAGATAAAGC CCCCTCACCA GGCTTGCCAG TGGAGATCAT CAAGGATTTA 360

ATGCGGCAGT TTCTAAGAGG CCTTGATTTC CTGCATGCCA ATTGCATCGT TCATCGGGAC 420

CTGAAGCCAG AGAACATTCT GATGACAAGC AATGGGACGG TCAAGCTGGC CGACGGCTTA 480

GCCAGAATCT ACAGCTATCA GATGGCCCTT ACACCTGTGG TGGTTGCACT CTGGTACAGG 540

GCTCCTGAAG TTCTTGTGCA ATCTGCATAT GCAACACCCG TGGACATGTG GAGTGTTGGC 600

TGTATCTTCC CAGAGATGTT TCGTCGGTTC TGTGGAAACT CGGATGCTGA CCTGTTAGGC 660

AACATTTTTC TGATCGGCTT GCCCCCAGAG GATGACTGGT CCCGAGATGT CTCTCTCCCC 720

CAGGGAGCCT TTCCCTCC 738

Domain Profile

S: 4     lekigeGtygkvykakdketgevvAlKkirlekeke...gvpitalrEisllkel...kh  57

         +++   Gtyg+vyka++ ++g++vA K++r+ + +    g+pi+++rE++ll++l   +h

Q: 9     VAENCVGTYGTVYKAREPHSGHFVARKSVRVPNGEGtgcGLPISTVREVALLRRLeafDH  68

         555567*************************997745669**************98889*

S: 58    knivkLlevva....kdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqllegl  113

         + +v+L++v+a      ++k++Lv+e+++qdL ++l+k ++ +l+ e +k l++q+l+gl

Q: 69    PSVVRLMDVCAtartDWETKVTLVLEHVDQDLRTYLDKAPSPGLPVEIIKDLMRQFLRGL  128

         ***********88644459*****************************************

S: 114   aylHsnkilHRDlKpqNlLiskegklklaDfGlarafssplktytkevvTlwYraPelLl  173

         ++lH+n i+HRDlKp+N+L++++g++klaD Glar +s ++  +t++vv lwYraPe+L+

Q: 129   DFLHANCIVHRDLKPENILMTSNGTVKLAD-GLARIYSYQMA-LTPVVVALWYRAPEVLV  186

         ******************************.********999.****************9

S: 174   gakeYstavDiWsvgcilaelltrkplfqgkseidqlerifkllgtpsekvwpevsklpe  233

         ++  Y t vD+Wsvgci+ e+++r   f g+s+ d l +if l+g p e++w++  +lp+

Q: 187   QS-AYATPVDMWSVGCIFPEMFRR---FCGNSDADLLGNIF-LIGLPPEDDWSRDVSLPQ  241

         87.5******************98...7************9.79*********9998886

Domain Sequence
(FASTA)

VAENCVGTYG TVYKAREPHS GHFVARKSVR VPNGEGTGCG LPISTVREVA LLRRLEAFDH 60

PSVVRLMDVC ATARTDWETK VTLVLEHVDQ DLRTYLDKAP SPGLPVEIIK DLMRQFLRGL 120

DFLHANCIVH RDLKPENILM TSNGTVKLAD GLARIYSYQM ALTPVVVALW YRAPEVLVQS 180

AYATPVDMWS VGCIFPEMFR RFCGNSDADL LGNIFLIGLP PEDDWSRDVS LPQ 233

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>