EKS-ECT-00012

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ECT-00012

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/PLK	409.2	5.4E-123	53	303	251

Status

Unreviewed

Ensembl Protein

ENSETEP00000015861

Gene Name

PLK1

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSETEG00000019524	ENSETEP00000015861	ENSETET00000019526

Organism

Echinops telfairi

Protein Length

554

Protein Sequence
(FASTA)

MSAAVTAGKL ARVPADTGKP GVPGAAAPGP TAAVPPAKEI PEVLVDPRSR RRYLRGRFLG 60

KGGFAKCFEI SDVDTKEVFA GKIVPKSLLL KPHQKEKMSM EISIHRSLAH LHVVGFHGFF 120

EDDFVFVVLE LCQRSLLELH KRRKALTEPE ARYYLRQIVL GCQYLHRNRV IHRDLKLGNL 180

FLNEDLEVKI GDFGLATKVE YDGERKKTLC GTPNYIAPEV LSKKGHSFEV DVWSIGCIMY 240

TLLVGKPPFE TSCLKETYLR IKKNEYSIPK HINPTAASLI QKMLQTDPCA RPTISELLND 300

EFFTSGYIPA RLPITCLTIP PRFSIAPSSL DSSTRKPLTV LNKGMENPVP ERPREKEEPV 360

AQEMGEAVDC HLSDMLQQLH SVNATKPSER GLVRQEEAED PACIPIFWIS KWVDYSDKYG 420

LCHPNSVMKM ITLLKYFRNY MSEHLLKAGA NITPREGDEL ARLPYLRTWF RTRSAIILHL 480

SNGCVQINFF QDHTKLILCP LMAAVTYINE KRDFRTYRLS LLEEHGCSKL ASRLRYARTM 540

VDKLLSSRSA TNRL 554

Nucleotide Sequence
(FASTA)

ATGAGTGCGG CGGTGACCGC AGGGAAGCTG GCGCGGGTCC CGGCCGACAC GGGGAAGCCC 60

GGGGTCCCCG GAGCTGCGGC TCCGGGCCCG ACGGCTGCGG TGCCGCCGGC CAAGGAGATC 120

CCGGAGGTCC TGGTGGACCC GCGCAGCCGG CGGCGCTATC TGCGGGGTCG CTTCCTGGGC 180

AAGGGAGGCT TTGCCAAGTG CTTCGAGATC TCGGATGTGG ACACCAAGGA GGTGTTCGCC 240

GGGAAGATCG TGCCGAAGTC GCTGCTGCTC AAGCCGCACC AGAAGGAGAA GATGTCCATG 300

GAGATTTCCA TTCACCGCAG TCTCGCCCAC CTACACGTCG TCGGCTTCCA CGGCTTTTTC 360

GAGGACGACT TCGTGTTCGT GGTCCTGGAA CTCTGCCAGA GGTCCCTGCT GGAGCTGCAC 420

AAGCGGAGGA AAGCGCTGAC GGAGCCCGAG GCCCGCTACT ACCTGCGGCA GATCGTCCTT 480

GGCTGCCAGT ATCTGCACCG CAATCGAGTC ATTCACCGGG ACCTCAAGCT GGGCAACCTC 540

TTTCTGAACG AAGATCTGGA GGTGAAAATA GGGGATTTTG GACTGGCCAC CAAAGTTGAG 600

TATGACGGGG AGCGGAAGAA GACACTGTGT GGGACTCCCA ACTACATCGC TCCTGAGGTG 660

CTGAGCAAGA AAGGGCACAG TTTCGAGGTG GACGTGTGGT CCATTGGGTG CATCATGTAT 720

ACTTTGTTAG TGGGCAAACC GCCGTTTGAG ACGTCCTGCC TAAAAGAGAC CTACCTCCGG 780

ATCAAGAAGA ATGAATACAG CATTCCTAAG CACATCAACC CCACGGCGGC CTCCCTCATC 840

CAGAAAATGC TTCAGACCGA TCCCTGCGCT CGCCCGACCA TTAGTGAGCT GCTGAACGAC 900

GAGTTCTTTA CTTCGGGTTA TATCCCTGCC CGGCTGCCCA TCACCTGCCT CACCATTCCA 960

CCCCGGTTCT CCATCGCTCC CAGCAGCCTG GACTCCAGCA CCCGGAAACC TCTCACAGTC 1020

CTCAATAAAG GCATGGAGAA CCCTGTGCCC GAACGTCCCC GGGAAAAAGA GGAGCCAGTG 1080

GCTCAGGAGA TGGGTGAGGC AGTTGACTGC CACCTCAGTG ACATGCTACA GCAGCTACAT 1140

AGCGTCAATG CCACTAAGCC CTCGGAACGG GGGCTAGTGA GGCAAGAGGA GGCTGAGGAT 1200

CCCGCCTGCA TTCCCATCTT CTGGATCAGC AAGTGGGTGG ACTATTCAGA CAAATATGGT 1260

CTTTGCCATC CGAATTCGGT AATGAAGATG ATCACACTCC TTAAGTATTT CCGGAATTAC 1320

ATGAGCGAAC ACTTGTTGAA GGCTGGTGCC AACATCACGC CACGGGAAGG GGATGAGCTG 1380

GCCCGGCTAC CCTACCTGCG GACCTGGTTC CGTACCCGCA GCGCCATCAT CCTGCATCTC 1440

AGCAATGGCT GTGTGCAGAT CAACTTTTTC CAGGACCATA CTAAACTCAT CCTGTGCCCG 1500

CTGATGGCGG CGGTGACCTA CATCAACGAG AAGCGGGACT TCCGCACGTA CCGCCTGAGC 1560

CTCCTGGAGG AGCACGGTTG CTCCAAGCTG GCCAGCCGCC TGCGCTACGC CCGCACCATG 1620

GTGGACAAGC TGCTGAGCTC CCGCTCGGCC ACCAACCGCC TC 1662

Domain Profile

S: 1     yergkllGkGgfakcyelkdletkevfavkvvpksllakekqrekvekeieihrslkhkn  60

         y rg++lGkGgfakc+e++d++tkevfa k+vpksll k++q+ek+++ei+ihrsl+h +

Q: 53    YLRGRFLGKGGFAKCFEISDVDTKEVFAGKIVPKSLLLKPHQKEKMSMEISIHRSLAHLH  112

         889*********************************************************

S: 61    ivklyeffedkenvylvlelcsrrslaellkrrkaltepevryylrqivsglkylhekri  120

         +v ++ ffed ++v++vlelc+r sl el+krrkaltepe+ryylrqiv g++ylh++r+

Q: 113   VVGFHGFFED-DFVFVVLELCQR-SLLELHKRRKALTEPEARYYLRQIVLGCQYLHRNRV  170

         *********9.69********85.899*********************************

S: 121   lhrdlklgnlflneelevkigdfGlatrlekeeerkktlcGtPnyiaPevlskkghslev  180

         +hrdlklgnlflne+levkigdfGlat++e+++erkktlcGtPnyiaPevlskkghs+ev

Q: 171   IHRDLKLGNLFLNEDLEVKIGDFGLATKVEYDGERKKTLCGTPNYIAPEVLSKKGHSFEV  230

         ************************************************************

S: 181   diWslGcilytllvGkPPfetkelketyekikkaeyslPsslskeaksliakllkkePee  240

         d+Ws+Gci+ytllvGkPPfet++lkety +ikk+eys+P++++++a+sli+k+l+++P +

Q: 231   DVWSIGCIMYTLLVGKPPFETSCLKETYLRIKKNEYSIPKHINPTAASLIQKMLQTDPCA  290

         ************************************************************

S: 241   rpsleevlkdefl  253

         rp+++e+l+def+

Q: 291   RPTISELLNDEFF  303

         ************8

Domain Sequence
(FASTA)

YLRGRFLGKG GFAKCFEISD VDTKEVFAGK IVPKSLLLKP HQKEKMSMEI SIHRSLAHLH 60

VVGFHGFFED DFVFVVLELC QRSLLELHKR RKALTEPEAR YYLRQIVLGC QYLHRNRVIH 120

RDLKLGNLFL NEDLEVKIGD FGLATKVEYD GERKKTLCGT PNYIAPEVLS KKGHSFEVDV 180

WSIGCIMYTL LVGKPPFETS CLKETYLRIK KNEYSIPKHI NPTAASLIQK MLQTDPCARP 240

TISELLNDEF F 251

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>