EKS-FEC-00196

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-FEC-00196

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDKL	464.3	1.0E-139	13	297	285

Status

Unreviewed

Ensembl Protein

ENSFCAP00000001003

Gene Name

CDKL5

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSFCAG00000001075	ENSFCAP00000001003	ENSFCAT00000001078

Organism

Felis catus

Protein Length

960

Protein Sequence
(FASTA)

MKIPNIGNVM NKFEILGVVG EGAYGVVLKC RHKETHEIVA IKKFKDSEEN EEVKETTLRE 60

LKMLRTLKQE NIVELKEAFR RRGKLYLVFE YVEKNMLELL EEMPNGVPPE KVKSYIYQLI 120

KAIHWCHKND IVHRDIKPEN LLISHNDVLK LCDFGFARNL SEGNNANYTE YVATRWYRSP 180

ELLLGAPYGK SVDMWSVGCI LGELSDGQPL FPGESEIDQL FTIQKVLGPL PSEQMKLFYS 240

NPRFHGLRFP AVNHPQTLER RYLGILNSVL LDLMKNLLKL DPADRYLTEQ CLNHPTFQTQ 300

RLLDRSPSRS AKRKPYHVES STLSNRNQAS KSTALQSHHR SNSKDIQNLS VGLPRADEGL 360

PANETFLNGN LAGATLSPMH TKTYQGSSQP GSTSKDLTNN NIPHLLSPKE AKSKTEFDFN 420

IDPKPSEGPG TKYLKSSSRS QQNRHSFMES SQSKAGTLQP SEKQSRHSYI DTIPQSSRSP 480

SYRTKAKSHG ALSDSKSVSN LSEARAQIAE SSTSRYFPSS CLDLNSPTSP TPTRHSDTRT 540

LLSPSGRNNR SEGTLDSRRT TTRHSKTMEE LKLPEHMDSS HSHSLSAPHE SFSYGLGYTS 600

PFSSQQRPHR HSMYVTRDKV RAKGLDGNLS VGQGMAARAN SLQLLSPQPG EQLPPEMTVA 660

RSSVKESSRE GTSSFHARQK SEGGAYHDPH SDDGTAPKEN RHLYNDPVPR RVGSFYRVPS 720

PRPDNSFHEN NVSTRVSSLP SESSSGTNHS KRQPAFDPWK SPENISHSEQ LKEKEKQGFF 780

RSMKKKKKKS QTVPNPDGPD LLTLQKAIHS ASTPGSRPKE WRPDKISDLQ TQSQPLKSLR 840

KLLHLSSASN HPASSDPRFQ PLTTQQAKNS FSEIRIHPLS QASGGSSNIR QEPTPKGRPA 900

LQLPGQMDPG WHVSSVSRSA TEGPSYSEQL GAKSGPNGHP YNRTNRSRMP NLNDLKETAL 960

Nucleotide Sequence
(FASTA)

ATGAAGATTC CTAACATTGG TAATGTGATG AATAAATTTG AGATCCTTGG GGTTGTAGGT 60

GAAGGAGCCT ATGGAGTTGT GCTTAAATGC AGACACAAGG AAACACATGA AATTGTGGCA 120

ATCAAGAAAT TCAAGGACAG TGAAGAAAAT GAAGAAGTCA AGGAAACGAC TTTACGAGAG 180

CTTAAAATGC TGCGTACTCT CAAGCAGGAA AACATCGTGG AGCTGAAGGA AGCCTTTCGT 240

CGGAGGGGGA AATTGTACTT GGTGTTTGAA TATGTTGAAA AAAATATGCT TGAACTGCTG 300

GAGGAAATGC CAAATGGAGT TCCACCTGAA AAAGTTAAAA GTTATATCTA TCAGCTAATC 360

AAAGCTATTC ACTGGTGCCA TAAGAACGAT ATTGTACATA GAGATATCAA GCCAGAAAAT 420

CTCTTAATCA GCCACAATGA TGTTTTGAAA CTGTGTGATT TTGGTTTTGC TCGGAATCTA 480

TCAGAAGGCA ATAATGCTAA TTATACAGAA TATGTGGCCA CCAGGTGGTA TCGGTCTCCA 540

GAACTCTTAC TTGGAGCTCC TTATGGAAAG TCCGTAGATA TGTGGTCAGT GGGCTGTATT 600

CTTGGGGAGC TCAGTGATGG ACAGCCTTTA TTTCCTGGAG AAAGTGAAAT CGACCAACTT 660

TTTACTATTC AGAAGGTGCT AGGACCACTT CCATCTGAGC AGATGAAGCT CTTCTACAGT 720

AATCCTCGAT TCCATGGGCT CCGGTTTCCA GCTGTTAACC ATCCTCAGAC ATTGGAGAGA 780

AGATACCTTG GAATTTTAAA TAGCGTCTTA CTTGACTTAA TGAAGAATTT ACTGAAGTTG 840

GACCCAGCTG ACAGATACCT GACAGAACAG TGTTTGAATC ACCCTACATT TCAAACCCAG 900

AGGCTTTTGG ATCGCTCCCC TTCAAGGTCA GCAAAAAGAA AACCTTACCA CGTGGAAAGC 960

AGCACTTTGT CTAATAGAAA TCAAGCCAGT AAAAGTACTG CTTTGCAGTC TCACCACAGA 1020

TCCAACAGCA AGGATATCCA GAACCTAAGT GTGGGTCTGC CCCGGGCTGA CGAAGGCCTT 1080

CCCGCCAATG AAACTTTCCT AAACGGAAAT CTTGCTGGAG CTACTCTTAG TCCCATGCAT 1140

ACCAAAACCT ATCAAGGAAG CAGCCAACCT GGGTCTACCA GCAAAGATCT TACCAACAAC 1200

AATATACCAC ATCTTCTCAG CCCAAAAGAA GCTAAGTCAA AGACAGAGTT TGATTTTAAT 1260

ATTGACCCGA AGCCTTCGGA AGGCCCAGGC ACAAAGTACC TCAAGTCAAG CAGCAGATCT 1320

CAGCAGAACC GGCACTCATT TATGGAAAGC TCTCAGAGCA AAGCCGGGAC GCTGCAGCCC 1380

AGTGAAAAAC AGAGCCGGCA TAGCTACATT GACACTATTC CCCAGTCCTC TAGGAGTCCC 1440

TCCTACAGGA CCAAGGCCAA AAGCCACGGG GCTTTGAGTG ACTCCAAGTC TGTGAGCAAC 1500

CTTTCTGAAG CCAGGGCCCA AATTGCAGAG TCTAGTACCA GTAGGTACTT CCCATCCAGC 1560

TGCTTGGACT TGAACTCTCC CACCAGCCCG ACCCCCACCA GGCACAGCGA CACGAGAACT 1620

TTGCTGAGCC CCTCGGGGAG AAATAATCGA AGTGAGGGCA CTCTTGACTC CCGCCGAACC 1680

ACAACCAGGC ATTCTAAAAC GATGGAGGAA TTAAAGCTGC CAGAGCACAT GGACAGCAGC 1740

CATTCCCATT CTCTGTCCGC ACCTCATGAA TCTTTTTCTT ATGGGCTGGG TTACACTAGC 1800

CCCTTTTCCT CCCAGCAGCG TCCACACAGG CATTCCATGT ACGTGACCCG GGACAAAGTG 1860

AGAGCCAAAG GCTTGGACGG AAACTTGAGC GTAGGGCAAG GAATGGCGGC CAGGGCCAAC 1920

AGCCTGCAGC TCTTATCACC TCAGCCTGGA GAACAGCTCC CTCCAGAGAT GACTGTGGCT 1980

CGATCTTCCG TTAAAGAATC CTCCAGAGAA GGCACCTCTT CATTCCACGC AAGGCAGAAG 2040

TCTGAGGGTG GAGCATATCA TGACCCCCAC TCTGATGATG GCACCGCCCC CAAAGAAAAT 2100

AGACACCTGT ACAATGATCC TGTTCCGAGG AGAGTTGGCA GTTTCTACCG AGTGCCATCT 2160

CCTCGTCCAG ACAATTCTTT CCATGAAAAT AATGTATCAA CCAGAGTGTC TTCCCTACCA 2220

TCAGAGAGTA GTTCTGGAAC TAACCACTCA AAAAGACAAC CAGCATTCGA TCCATGGAAA 2280

AGTCCTGAAA ACATTAGTCA TTCTGAACAA CTCAAGGAAA AGGAAAAACA AGGTTTTTTC 2340

AGGTCAATGA AAAAGAAAAA GAAGAAATCT CAAACAGTAC CCAATCCTGA TGGCCCTGAT 2400

CTTCTGACAC TACAGAAAGC CATTCACTCT GCTAGCACCC CGGGCAGCAG ACCAAAGGAG 2460

TGGCGTCCTG ACAAGATCTC TGATTTACAG ACCCAAAGCC AGCCGTTAAA ATCACTGCGC 2520

AAGCTGTTAC ATCTCTCTTC AGCCTCAAAT CACCCGGCTT CCTCAGACCC CCGCTTCCAG 2580

CCCTTAACAA CTCAACAAGC CAAAAATTCC TTCTCAGAAA TTCGGATCCA CCCCCTGAGC 2640

CAGGCCTCTG GCGGGAGCAG TAACATCCGG CAGGAGCCCA CACCCAAGGG CCGGCCAGCC 2700

CTCCAGCTGC CAGGTCAGAT GGACCCTGGT TGGCACGTGT CCTCTGTGAG CCGGAGTGCC 2760

ACAGAGGGGC CCTCCTACTC TGAACAGCTG GGTGCCAAGA GTGGGCCAAA CGGGCACCCT 2820

TATAACAGAA CAAATCGGTC TCGAATGCCA AATCTGAATG ATTTAAAAGA GACAGCCTTG 2880

TAG 2883

Domain Profile

S: 1     yeklgkvGeGsyGvvlkcrnkdtgqivaikkfleseddkevkkialreikllkqlkhenl  60

         +e lg+vGeG+yGvvlkcr+k+t++ivaikkf++se+++evk+++lre+k+l++lk+en+

Q: 13    FEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTLKQENI  72

         799*********************************************************

S: 61    vnllevfrrkkklylvfeyvdktvldelerypnGveeelvkkilyqilkaiefchknnii  120

         v+l+e+frr+ klylvfeyv+k++l+ le++pnGv+ e+vk+++yq++kai++chkn+i+

Q: 73    VELKEAFRRRGKLYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQLIKAIHWCHKNDIV  132

         ************************************************************

S: 121   hrdikpenilisksgvvklcdfGfarlla.apgdvytdyvatrwyrapellvgdtkyGks  179

         hrdikpen+lis+++v+klcdfGfar+l+ +++++yt+yvatrwyr+pell+g + yGks

Q: 133   HRDIKPENLLISHNDVLKLCDFGFARNLSeGNNANYTEYVATRWYRSPELLLG-APYGKS  191

         ****************************98999********************.9*****

S: 180   vdvwaiGcllaelltGeplfpgksdvdqlykirktlGeliprhqkifsknevfaGvklpe  239

         vd+w++Gc+l el++G+plfpg+s++dql++i+k+lG+l ++++k+f++n++f+G+++p+

Q: 192   VDMWSVGCILGELSDGQPLFPGESEIDQLFTIQKVLGPLPSEQMKLFYSNPRFHGLRFPA  251

         ************************************************************

S: 240   vedleslekkyp.klnevlldllkkclkldpaerlsceellkheyf  284

         v+++++le++y   ln+vlldl+k++lkldpa+r+++e++l+h++f

Q: 252   VNHPQTLERRYLgILNSVLLDLMKNLLKLDPADRYLTEQCLNHPTF  297

         ***********9899****************************998

Domain Sequence
(FASTA)

FEILGVVGEG AYGVVLKCRH KETHEIVAIK KFKDSEENEE VKETTLRELK MLRTLKQENI 60

VELKEAFRRR GKLYLVFEYV EKNMLELLEE MPNGVPPEKV KSYIYQLIKA IHWCHKNDIV 120

HRDIKPENLL ISHNDVLKLC DFGFARNLSE GNNANYTEYV ATRWYRSPEL LLGAPYGKSV 180

DMWSVGCILG ELSDGQPLFP GESEIDQLFT IQKVLGPLPS EQMKLFYSNP RFHGLRFPAV 240

NHPQTLERRY LGILNSVLLD LMKNLLKLDP ADRYLTEQCL NHPTF 285

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>