EKS-FEC-00027

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-FEC-00027

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TK/Jak	348.1	3.6E-104	876	1148	273

Status

Unreviewed

Ensembl Protein

ENSFCAP00000001806

Gene Name

JAK1

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSFCAG00000001953	ENSFCAP00000001806	ENSFCAT00000001953

Organism

Felis catus

Protein Length

1155

Protein Sequence
(FASTA)

MQYLNIKEDC NAMAFCAKMR SSKKTEVNLE APEPGVEVLF YLSDREPLRL GSGEYTAEEL 60

CIRAAQECCI SPLCHNLFAL YDENTKLWYA PNRMITVDDK TSLRLHYRMR FYFTNWHGTN 120

DNEQSVWRHS PKKQKNGYEK KKVPDATPLL DASSLEYLFA QGQYDLVKCL APIRDPKTEQ 180

DGHDIENECL GMAVLAISHY AMMKKMQLPE LPKDISYKRY IPETLNKSIR QRNLLTRMRI 240

NNVFKDFLKE FNNKTICDSS VSTHDLKVKY LATLETLTKH YGAEIFETSM LLISSENEMN 300

WFHPDDSGNI LYEVMVTGNL GIQWRQKPNV VPVEKEKNKL KWKKLENKHK KDEEKNKIRE 360

EWNNFSYFPE ITHIVIKECV VSINKQDNKK MELKLSSHEE ALSFVSLVDG YFRLTADAHH 420

YLCTDVAPPL IVHNIQNGCH GPICTEYAIN KLRQEGSEEG MYVLRWSCTD FDNILMTVTC 480

FEKSEEWQVV GSLKQFKNFQ IEVQKGRYSL HGSDRSFPSL GDLMNHLKKQ ILRTDNISFV 540

LKRCCQPKPR EISNLLVATK KAQEWQPVYS MSQLSFDRIL KKDIVQGEHL GRGTRTHIYS 600

GTLLDYKDDE GTSEEKRIKV ILKVLDPSHR DISLAFFEAA SMMRQVSHKH IVYLYGVCVR 660

DVENIMVEEF VEGGPLDLFM HRKSDVLTTP WKFKVAKQLA SALSYLEDKD LVHGNVCTKN 720

LLLAREGIDS EFGPFIKLSD PGIPITVLSR QECIERIPWI APECVEDSKN LSVAADKWSF 780

GTTLWEICYN GEIPLKDKTL IEKERFYESR CRPVTPSCKE LADLMTRCMN YDPNQRPFFR 840

AIMRDINKLE EQNPDIVSER KPATEVDPTH FEKRFLKRIR DLGEGHFGKV ELCRYDPEGD 900

NTGEQVAVKS LKPESGGNHI ADLKKEIEIL RNLYHENIVK YKGICTEDGG NGIKLIMEFL 960

PSGSLKEYLP KNKNKINLKQ QLKYAVQICK GMDYLGSRQY VHRDLAARNV LVESEHQVKI 1020

GDFGLTKAIE TDKEYYTVKD DRDSPVFWYA PECLIQCKFY IASDVWSFGV TLHELLTYCD 1080

SDSSPMALFL KMIGPTHGQM TVTRLVNTLK EGKRLPCPPN CPDEVYQLMR KCWEFQPANR 1140

TTFQNLIKGF EALLE 1155

Nucleotide Sequence
(FASTA)

ATGCAGTATC TAAATATAAA AGAGGACTGC AATGCCATGG CTTTCTGTGC TAAAATGAGG 60

AGCTCCAAGA AGACGGAGGT GAATCTGGAG GCCCCCGAAC CAGGGGTGGA AGTGCTCTTC 120

TATCTGTCCG ATAGGGAGCC GCTCCGGCTG GGCAGCGGGG AGTACACGGC AGAGGAGCTG 180

TGCATCAGGG CGGCGCAGGA ATGCTGTATC TCTCCTCTGT GTCACAACCT TTTTGCCCTG 240

TATGATGAGA ACACCAAGCT TTGGTATGCT CCGAATCGCA TGATCACAGT TGACGACAAG 300

ACATCACTCC GGCTCCACTA CCGGATGAGG TTCTATTTCA CCAACTGGCA TGGGACCAAT 360

GATAATGAGC AGTCTGTATG GCGACATTCT CCGAAGAAGC AGAAAAATGG CTACGAGAAA 420

AAAAAAGTTC CAGATGCAAC CCCTCTCCTT GACGCCAGCT CCCTGGAGTA TCTGTTTGCT 480

CAGGGACAAT ATGATTTGGT CAAATGCCTG GCTCCCATTC GAGACCCCAA GACCGAGCAG 540

GATGGACACG ATATTGAGAA CGAGTGTCTG GGAATGGCTG TCCTGGCCAT CTCCCACTAC 600

GCCATGATGA AGAAGATGCA ATTGCCAGAA CTGCCCAAGG ACATCAGCTA CAAGCGATAT 660

ATCCCAGAAA CATTGAATAA GTCCATCAGG CAGAGGAATC TTCTCACCAG GATGCGGATA 720

AATAACGTTT TCAAGGATTT CCTAAAGGAA TTTAACAACA AGACCATCTG TGACAGCAGT 780

GTATCTACTC ATGACCTGAA GGTGAAATAC CTGGCGACCT TGGAGACTTT GACAAAACAT 840

TATGGTGCTG AAATATTTGA GACTTCCATG TTACTGATTT CGTCAGAAAA TGAGATGAAT 900

TGGTTTCATC CAGATGACAG TGGAAACATT CTCTATGAAG TGATGGTAAC TGGAAATCTT 960

GGAATCCAGT GGAGACAGAA ACCAAATGTT GTTCCTGTTG AAAAGGAAAA AAACAAACTG 1020

AAATGGAAAA AGCTGGAAAA TAAACACAAG AAGGATGAGG AGAAAAACAA AATCCGGGAA 1080

GAGTGGAACA ATTTTTCTTA CTTCCCTGAA ATCACTCACA TTGTAATAAA GGAGTGTGTG 1140

GTCAGCATCA ATAAGCAGGA CAATAAAAAA ATGGAACTGA AGCTTTCGTC CCACGAGGAG 1200

GCCTTGTCCT TTGTGTCCCT GGTAGACGGC TACTTCCGGC TCACAGCAGA TGCCCATCAT 1260

TACCTCTGCA CTGATGTGGC TCCCCCACTG ATTGTCCACA ACATACAGAA TGGTTGTCAC 1320

GGTCCCATCT GCACGGAATA TGCCATCAAT AAGTTGCGGC AAGAAGGAAG TGAGGAGGGA 1380

ATGTATGTGC TGAGGTGGAG CTGTACCGAC TTTGACAATA TCCTCATGAC TGTCACCTGC 1440

TTTGAAAAAT CTGAGGAATG GCAGGTGGTG GGTAGCCTGA AACAGTTCAA GAACTTTCAG 1500

ATCGAGGTGC AGAAGGGCCG TTACAGCCTG CATGGCTCGG ACCGCAGCTT CCCCAGCCTG 1560

GGGGACCTCA TGAACCACCT CAAGAAACAG ATCCTGCGGA CGGACAACAT CAGCTTCGTG 1620

CTGAAACGCT GCTGCCAACC CAAGCCCCGA GAGATCTCCA ATTTGCTGGT GGCTACTAAG 1680

AAAGCCCAGG AGTGGCAGCC TGTCTACTCT ATGAGCCAGC TGAGTTTTGA CCGGATCCTC 1740

AAGAAAGATA TCGTGCAAGG AGAGCACCTT GGGAGAGGCA CGCGGACGCA TATCTACTCT 1800

GGAACCCTTC TGGATTACAA AGATGACGAA GGAACTTCCG AAGAAAAGAG AATAAAAGTG 1860

ATCCTCAAAG TCTTAGACCC CAGCCACAGG GACATTTCTC TGGCCTTCTT TGAGGCAGCC 1920

AGCATGATGA GGCAGGTCTC CCACAAACAC ATCGTGTACC TCTATGGCGT CTGTGTCCGA 1980

GATGTGGAAA ATATCATGGT GGAGGAGTTT GTGGAGGGGG GGCCCCTGGA TCTCTTCATG 2040

CACCGGAAAA GCGATGTCCT CACCACACCG TGGAAGTTTA AAGTTGCCAA ACAACTGGCT 2100

AGTGCCTTGA GTTACTTGGA GGATAAAGAC CTGGTCCACG GAAATGTGTG CACTAAAAAC 2160

CTCCTCTTGG CCCGTGAGGG CATCGACAGT GAGTTCGGCC CGTTCATCAA GCTCAGTGAC 2220

CCCGGCATCC CCATCACCGT GCTGTCCAGG CAAGAGTGCA TAGAACGAAT CCCGTGGATT 2280

GCTCCCGAGT GTGTTGAAGA CTCCAAGAAC CTGAGTGTGG CCGCTGACAA ATGGAGCTTT 2340

GGAACCACAC TCTGGGAAAT CTGCTACAAT GGCGAGATCC CTCTGAAAGA CAAGACACTG 2400

ATTGAGAAAG AGCGATTCTA TGAAAGCCGG TGCCGGCCAG TGACACCATC TTGTAAGGAG 2460

CTGGCTGACC TCATGACCCG CTGCATGAAC TATGACCCCA ACCAGAGACC CTTCTTCCGA 2520

GCCATCATGA GAGACATCAA TAAACTGGAG GAGCAGAATC CAGACATTGT TTCGGAACGA 2580

AAGCCGGCAA CCGAAGTGGA TCCCACACAT TTTGAAAAGC GGTTCTTGAA GAGAATCCGT 2640

GACTTGGGAG AGGGCCACTT TGGGAAGGTT GAGCTCTGCA GATACGACCC TGAGGGTGAC 2700

AATACCGGGG AGCAGGTGGC TGTCAAATCC CTGAAGCCTG AGAGTGGAGG TAACCACATA 2760

GCTGATCTGA AGAAGGAAAT TGAAATCTTA AGGAACCTCT ATCATGAGAA CATTGTGAAG 2820

TACAAAGGCA TCTGTACAGA AGACGGAGGA AATGGTATTA AGCTCATCAT GGAGTTTCTA 2880

CCTTCAGGAA GCCTTAAGGA ATATCTTCCA AAGAATAAGA ACAAAATTAA CCTCAAACAA 2940

CAGTTAAAAT ATGCTGTTCA GATTTGTAAG GGGATGGACT ACTTGGGGTC TCGGCAGTAC 3000

GTTCACCGGG ACTTAGCAGC AAGAAATGTC CTCGTTGAGA GTGAGCACCA AGTGAAAATT 3060

GGAGACTTCG GTTTAACCAA AGCCATTGAA ACCGACAAAG AGTACTACAC AGTCAAGGAT 3120

GATCGGGACA GCCCTGTGTT TTGGTATGCT CCAGAATGTT TAATTCAGTG TAAATTTTAT 3180

ATCGCCTCTG ACGTCTGGTC GTTTGGAGTG ACTCTGCATG AGCTGCTCAC TTACTGTGAC 3240

TCCGATTCTA GCCCCATGGC ATTGTTCCTG AAAATGATAG GCCCAACGCA TGGCCAGATG 3300

ACAGTCACAA GACTTGTGAA CACGTTAAAA GAAGGAAAAC GTTTGCCCTG TCCACCTAAC 3360

TGCCCAGATG AGGTTTATCA ACTCATGAGA AAGTGCTGGG AATTCCAACC AGCTAATAGG 3420

ACAACTTTTC AGAACCTAAT TAAAGGATTT GAAGCACTTT TAGAA 3465

Domain Profile

S: 1     lkqiesLgkgtftkvfevredaegdsteeevalkvLk.esgedisrdfkreaeilsqlsh  59

         lk+i++Lg+g+f+kv+++r+d+egd+t+e+va+k Lk esg ++++d+k+e+eil++l+h

Q: 876   LKRIRDLGEGHFGKVELCRYDPEGDNTGEQVAVKSLKpESGGNHIADLKKEIEILRNLYH  935

         6899********************************************************

S: 60    ehivklkgvcvaegen..rlVmeyvesGsLdiyLrkkkealslsslldvakqlakameYL  117

         e+ivk+kg+c+++g n  +l+me+++sGsL++yL+k+k++++l+++l++a q++k+m+YL

Q: 936   ENIVKYKGICTEDGGNgiKLIMEFLPSGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYL  995

         ************************************************************

S: 118   edkklvhrdvaarnvLveresnegtppfvklsdpglakavnqd.eYylvreerdsripwl  176

         +++++vhrd+aarnvLve+e++      vk++d+gl+ka+++d eYy+v+++rds+++w+

Q: 996   GSRQYVHRDLAARNVLVESEHQ------VKIGDFGLTKAIETDkEYYTVKDDRDSPVFWY  1049

         **********************......********************************

S: 177   apeclseaknlstasdvWsFgvtlyellt.cskgesp....lrsesle.......rklel  224

         apecl+++k +++asdvWsFgvtl+ellt c++++sp    l++++++       r++++

Q: 1050  APECLIQCK-FYIASDVWSFGVTLHELLTyCDSDSSPmalfLKMIGPThgqmtvtRLVNT  1108

         *********.*******************************9****999***********

S: 225   leekerlpkpk.cpaelaelmtnclsyepsqrpsFraile  263

         l+e++rlp+p+ cp+e+++lm++c++ +p +r++F+++++

Q: 1109  LKEGKRLPCPPnCPDEVYQLMRKCWEFQPANRTTFQNLIK  1148

         *************************************986

Domain Sequence
(FASTA)

LKRIRDLGEG HFGKVELCRY DPEGDNTGEQ VAVKSLKPES GGNHIADLKK EIEILRNLYH 60

ENIVKYKGIC TEDGGNGIKL IMEFLPSGSL KEYLPKNKNK INLKQQLKYA VQICKGMDYL 120

GSRQYVHRDL AARNVLVESE HQVKIGDFGL TKAIETDKEY YTVKDDRDSP VFWYAPECLI 180

QCKFYIASDV WSFGVTLHEL LTYCDSDSSP MALFLKMIGP THGQMTVTRL VNTLKEGKRL 240

PCPPNCPDEV YQLMRKCWEF QPANRTTFQN LIK 273

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>