EKS-FEC-00067

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-FEC-00067

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	354.0	5.5E-106	10	297	288

Status

Unreviewed

Ensembl Protein

ENSFCAP00000002522

UniProt Accession

A4GRV3;

Protein Name

Protein Synonyms/Alias

Cyclin-dependent kinase 6;

Gene Name

CDK6

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSFCAG00000002746	ENSFCAP00000002522	ENSFCAT00000002744

Organism

Felis catus

Functional Description

Protein Length

323

Protein Sequence
(FASTA)

DGLSRADQQY ECVAEIGEGA YGKVFKARDL KNGGRFVALK RVRVQTGEEG MPLSTIREVA 60

VLRHLETFEH PNVVRLFDVC TVSRTDRETK LTLVFEHVDQ DLTTYLDKVP EPGVPTETIK 120

DMMFQLLRGL DFLHSHRVVH RDLKPQNILV TSSGQIKLAD FGLARIYSFQ MALTSVVVTL 180

WYRAPEVLLQ SSYATPVDLW SVGCIFAEMF RRKPLFRGSS DVDQLGKILD VIGLPGEEDW 240

PRDVALPRQA FHSKSPQPIE KFVTDIDEQG KDLLLKCLTF NPAKRISAYS ALSHPYFHDL 300

ERCKENLDSR LPPSQNSSEM NTA 323

Nucleotide Sequence
(FASTA)

GACGGCCTGA GCCGCGCGGA CCAGCAGTAC GAGTGCGTGG CGGAGATCGG GGAGGGCGCC 60

TATGGAAAGG TGTTCAAGGC CCGGGACCTG AAGAACGGAG GCCGGTTCGT GGCGCTGAAG 120

CGCGTGCGGG TGCAGACAGG CGAGGAGGGC ATGCCGCTCT CCACCATCCG CGAGGTGGCG 180

GTGCTGAGGC ACCTGGAGAC CTTCGAGCAC CCCAACGTGG TCAGGTTGTT TGATGTATGC 240

ACAGTGTCAC GAACAGACAG AGAAACCAAA CTAACATTAG TGTTTGAACA TGTTGATCAA 300

GACCTGACCA CTTATTTGGA TAAAGTCCCG GAGCCTGGAG TGCCCACTGA AACCATAAAG 360

GATATGATGT TTCAGCTTCT CCGAGGTCTG GACTTTCTTC ATTCTCACCG AGTAGTGCAT 420

CGTGATCTAA AACCGCAGAA CATTCTGGTG ACCAGCAGCG GACAAATAAA ACTGGCTGAC 480

TTTGGCCTTG CCCGCATCTA CAGTTTTCAG ATGGCTCTTA CCTCAGTGGT CGTCACGCTG 540

TGGTACAGAG CTCCAGAAGT CTTGCTTCAG TCCAGCTACG CCACCCCCGT GGACCTCTGG 600

AGTGTTGGCT GCATATTTGC AGAAATGTTT CGTAGAAAGC CTCTTTTTCG TGGAAGTTCA 660

GACGTTGATC AACTTGGAAA AATCTTGGAT GTAATTGGAC TCCCAGGAGA AGAAGACTGG 720

CCCAGAGATG TCGCCCTTCC CAGACAGGCT TTTCACTCAA AATCTCCTCA ACCAATTGAG 780

AAGTTCGTAA CAGATATTGA TGAACAAGGC AAAGACCTAC TCCTGAAGTG CCTAACCTTT 840

AATCCGGCCA AAAGAATATC TGCCTACAGT GCCCTGTCTC ACCCCTACTT CCATGATCTG 900

GAGAGGTGCA AGGAGAATCT GGATTCCCGT CTGCCTCCCA GCCAGAACAG CTCAGAGATG 960

AATACAGCC 969

Domain Profile

S: 1     yeklekigeGtygkvykakd.ketgevvAlKkirlekekegvpitalrEisllkel...k  56

         ye++++igeG+ygkv+ka+d k+ g++vAlK++r+++ +eg+p +++rE+++l++l   +

Q: 10    YECVAEIGEGAYGKVFKARDlKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLetfE  69

         899*****************888999*****************************98889

S: 57    hknivkLlevva....kdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqlleg  112

         h+n+v+L +v++     +++kl+Lvfe+++qdL+++l+k ++ ++++e++k +++qll+g

Q: 70    HPNVVRLFDVCTvsrtDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLLRG  129

         ************99855569****************************************

S: 113   laylHsnkilHRDlKpqNlLiskegklklaDfGlarafssplktytkevvTlwYraPelL  172

         l++lHs++++HRDlKpqN+L++++g++klaDfGlar +s ++  +t++vvTlwYraPe+L

Q: 130   LDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMA-LTSVVVTLWYRAPEVL  188

         *****************************************99.****************

S: 173   lgakeYstavDiWsvgcilaelltrkplfqgkseidqlerifkllgtpsekvwpevsklp  232

         l++ +Y t vD+Wsvgci+ae+++rkplf+g+s++dql +i++++g p e++wp+   lp

Q: 189   LQS-SYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWPRDVALP  247

         *88.5*******************************************************

S: 233   eykksfpkkkkkklkekvkklkekaldllekllaldpkkRisakealqhkyf  284

         +   +f++k+++ +++ v++++e++ dll k+l+++p+kRisa +al+h+yf

Q: 248   RQ--AFHSKSPQPIEKFVTDIDEQGKDLLLKCLTFNPAKRISAYSALSHPYF  297

         95..599999*****************************************9

Domain Sequence
(FASTA)

YECVAEIGEG AYGKVFKARD LKNGGRFVAL KRVRVQTGEE GMPLSTIREV AVLRHLETFE 60

HPNVVRLFDV CTVSRTDRET KLTLVFEHVD QDLTTYLDKV PEPGVPTETI KDMMFQLLRG 120

LDFLHSHRVV HRDLKPQNIL VTSSGQIKLA DFGLARIYSF QMALTSVVVT LWYRAPEVLL 180

QSSYATPVDL WSVGCIFAEM FRRKPLFRGS SDVDQLGKIL DVIGLPGEED WPRDVALPRQ 240

AFHSKSPQPI EKFVTDIDEQ GKDLLLKCLT FNPAKRISAY SALSHPYF 288

Keyword

Cyclin; Kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sorex araneus"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>