EKS-FEC-00388

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-FEC-00388

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TK/PDGFR	581.4	7.0E-175	616	949	334

Status

Unreviewed

Ensembl Protein

ENSFCAP00000004196

Gene Name

FLT3

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSFCAG00000004539	ENSFCAP00000004196	ENSFCAT00000004543

Organism

Felis catus

Protein Length

996

Protein Sequence
(FASTA)

KVCVLSTSLS LFCFTVVFSA MIFETITNQD LPVIKCVLIN HKNNDSSLGI SSSYPMVNRK 60

PESDEQNCND GRQSQSVLGV TCLPDVWGDV SVTDSYQLFA FVPLSYLYLG VKPKPSCRQH 120

FGFKKCSGVV SMVILKMTET QAGEYLLFIQ SEATNYTILF TVSIRNTNAR SLRKPYYLQC 180

KNRTAATQVH CNVLSASCWW EIPCPIYICS CKGESPAVVT KEESVLHELF GTDIRCCASN 240

ELGRKCTKLF TIDLNQTPQT TLPQLFLKVG EPLWIRCKAV HVNHGFGLTW ELENKALEEG 300

SYFEMSTYST NRTMIRILFA FVSSVGRNDT GHYTCSSSEH PSKSTLVTII EKGFINASKS 360

SEDYEIDQYE EFCFSVRFKA YPQIRCTWTF SQKSFPCEQS GLDDGYSISK FCNHKHQPGE 420

YIFHAENDDA EFTKMFTLNI RRKPQVVVEG SSASQASCSS DGYPLPSWIW KKCSDKSPNC 480

TEEITEGIWN KTANRKVFGQ WISSSTLNMS EAVKGFLVKC CAYNSLGTSC ETILLNASVP 540

FAFIQDNILF YATLGLCLPF IAVLTMLICH KYKKQFRYES QLQMVQVTGS LDNEYFYVDF 600

REYEYDLKWE FPRENLEFGK VLGSGAFGKV MNATAYGISQ TGVSIQVAVK MLKEKADSSE 660

REALMSELKM MSHLGNHENI VNLLGACTLS GPVYLIFEYC CYGDLLNYLR NKREKFHRTW 720

TEIFKEHNFS FYPAFQSYPN SSMPGSREVQ IRQDLDHISG FNGNSFQSED EIEYENQKRL 780

EEEEDLNVLT FEDLLCFAYQ VAKGMEFLEF KSCVHRDLAA RNVLVTHGKV VKICDFGLAR 840

DIMSDSNYVI RGNARLPVKW MAPESLFEGV YTIKSDVWSY GILLWEIFSL GVNPYPGIPV 900

DANFYKLIQS GFKMDQPFYA TEEIYFIMQS CWAFDSRKRP SFPNLTSFLG CQLADAEEAG 960

DIHPPSHRGE PLTPGWCSGL QSRSPGSRAE IGLQAP 996

Nucleotide Sequence
(FASTA)

AAGGTGTGCG TGTTATCAAC ATCCTTGTCT TTATTTTGTT TTACAGTTGT TTTTTCAGCA 60

ATGATATTTG AGACTATTAC AAATCAAGAT CTGCCTGTGA TCAAGTGTGT TTTAATCAAT 120

CATAAGAACA ATGATTCATC ACTGGGGATA TCATCATCGT ATCCCATGGT AAACAGAAAG 180

CCAGAATCTG ATGAGCAGAA TTGCAATGAT GGGCGACAGT CACAAAGTGT CTTAGGGGTA 240

ACCTGCCTGC CTGACGTATG GGGGGATGTA TCCGTGACCG ACTCGTACCA ACTTTTTGCA 300

TTTGTTCCTT TAAGTTACTT GTATCTTGGG GTTAAACCAA AGCCCTCTTG TAGGCAGCAT 360

TTTGGCTTCA AGAAATGTTC TGGGGTTGTT TCCATGGTCA TTTTGAAAAT GACAGAAACC 420

CAAGCTGGAG AATACCTACT TTTCATTCAG AGTGAAGCTA CCAATTATAC AATATTGTTT 480

ACAGTGAGTA TAAGAAATAC AAATGCTAGA TCACTACGCA AACCGTATTA TTTACAGTGT 540

AAAAATAGGA CAGCAGCTAC CCAAGTTCAT TGTAATGTGC TTTCAGCATC CTGCTGGTGG 600

GAAATCCCAT GTCCTATTTA CATTTGCAGC TGTAAAGGGG AGAGTCCGGC AGTTGTCACG 660

AAGGAGGAAA GCGTACTTCA TGAACTGTTT GGAACAGACA TAAGGTGCTG TGCAAGCAAT 720

GAGCTGGGTA GAAAGTGCAC CAAGCTGTTC ACAATAGATC TCAATCAGAC TCCGCAGACC 780

ACACTGCCAC AACTATTTCT TAAAGTAGGG GAACCCTTAT GGATAAGGTG CAAAGCTGTT 840

CATGTGAATC ATGGATTCGG ACTCACCTGG GAATTAGAAA ATAAAGCCTT GGAGGAGGGC 900

AGCTACTTTG AGATGAGTAC CTATTCTACA AACAGAACTA TGATACGGAT TCTGTTTGCT 960

TTTGTATCAT CAGTGGGAAG AAACGACACT GGCCATTACA CTTGTTCCTC TTCCGAACAT 1020

CCCAGTAAAT CAACTTTGGT TACCATCATA GAAAAAGGAT TTATAAACGC TTCCAAATCA 1080

AGTGAAGATT ATGAGATTGA CCAGTATGAA GAGTTTTGCT TTTCTGTCAG GTTTAAAGCA 1140

TACCCACAAA TCAGGTGTAC GTGGACCTTC TCTCAAAAAT CATTTCCTTG TGAGCAGAGC 1200

GGCCTTGATG ATGGGTACAG CATATCTAAG TTTTGCAACC ATAAACACCA GCCAGGAGAA 1260

TACATATTTC ATGCAGAAAA CGATGATGCC GAATTCACAA AAATGTTCAC GCTGAACATA 1320

AGAAGGAAAC CTCAGGTGGT AGTCGAGGGA TCATCAGCAA GTCAGGCTTC TTGCTCCTCT 1380

GATGGGTACC CATTACCATC TTGGATCTGG AAGAAGTGTT CAGACAAGTC TCCCAACTGC 1440

ACAGAGGAAA TCACAGAAGG AATTTGGAAT AAAACGGCTA ACAGAAAAGT GTTTGGACAA 1500

TGGATATCAA GCAGTACTCT TAACATGAGT GAGGCCGTAA AAGGGTTCCT GGTGAAGTGC 1560

TGTGCATACA ATTCCCTTGG CACATCTTGT GAAACAATCC TTTTAAACGC CTCAGTGCCC 1620

TTCGCTTTCA TCCAAGACAA CATCTTGTTC TATGCGACCC TTGGGCTTTG TCTTCCCTTC 1680

ATCGCTGTTC TAACCATGCT CATCTGTCAC AAGTACAAAA AGCAATTTAG GTACGAAAGC 1740

CAGCTGCAAA TGGTGCAGGT GACCGGCTCT TTGGATAATG AGTACTTCTA CGTTGACTTC 1800

AGAGAATATG AATACGATCT CAAGTGGGAG TTTCCAAGAG AAAACTTAGA ATTTGGGAAG 1860

GTCCTGGGAT CAGGTGCTTT TGGAAAAGTG ATGAATGCGA CAGCTTACGG AATTAGTCAA 1920

ACGGGAGTCT CAATCCAGGT GGCAGTCAAA ATGCTGAAAG AAAAAGCAGA CAGTTCCGAA 1980

AGAGAGGCTC TCATGTCCGA ACTCAAAATG ATGAGTCACC TGGGAAACCA TGAGAATATC 2040

GTAAATCTGC TGGGGGCCTG CACACTGTCA GGACCAGTTT ACTTGATTTT TGAATACTGT 2100

TGCTATGGTG ATCTTCTCAA CTACCTAAGA AATAAGAGAG AAAAATTTCA CAGGACGTGG 2160

ACGGAGATTT TCAAGGAGCA CAATTTCAGT TTTTACCCCG CTTTCCAATC ATACCCAAAT 2220

TCCAGCATGC CTGGTTCAAG AGAAGTTCAG ATACGCCAGG ACTTGGATCA CATCTCAGGG 2280

TTCAACGGGA ACTCATTTCA ATCTGAAGAT GAAATCGAAT ATGAAAACCA AAAGAGGCTG 2340

GAAGAAGAAG AGGACTTGAA CGTGCTGACA TTTGAGGATC TTCTCTGCTT CGCCTATCAA 2400

GTTGCCAAGG GAATGGAATT TCTGGAATTT AAGTCGTGTG TTCACAGAGA CCTGGCGGCC 2460

AGGAACGTGC TCGTGACCCA CGGGAAAGTG GTGAAGATCT GTGACTTTGG ACTGGCTCGA 2520

GATATCATGA GTGACTCCAA CTACGTTATC CGGGGCAATG CCCGTCTCCC TGTAAAGTGG 2580

ATGGCTCCCG AAAGCTTATT TGAAGGGGTC TACACCATAA AGAGTGACGT CTGGTCATAT 2640

GGAATATTAC TCTGGGAAAT ATTCTCACTT GGTGTCAATC CGTACCCTGG CATTCCGGTC 2700

GACGCTAACT TCTATAAACT CATTCAGAGT GGATTTAAGA TGGACCAGCC ATTTTATGCT 2760

ACAGAAGAAA TATACTTTAT AATGCAATCG TGCTGGGCTT TTGACTCGAG GAAACGGCCG 2820

TCCTTCCCCA ACCTGACCTC GTTTTTAGGA TGTCAGCTGG CCGATGCAGA AGAAGCGGGA 2880

GACATTCATC CGCCCAGCCA CCGTGGGGAG CCTCTCACCC CCGGCTGGTG CAGTGGGCTC 2940

CAGTCTAGAA GCCCGGGGAG CAGAGCAGAG ATTGGACTTC AGGCCCCC 2988

Domain Profile

S: 1     lelGkvlGsGafGkvveatayGlsksdavlkvavkmlkstarssekealmselkilshlG  60

         le+GkvlGsGafGkv++atayG+s+++++++vavkmlk++a+sse+ealmselk++shlG

Q: 616   LEFGKVLGSGAFGKVMNATAYGISQTGVSIQVAVKMLKEKADSSEREALMSELKMMSHLG  675

         79**********************************************************

S: 61    ehenivnllGactkgGpiyviteyccyGdllnylrrkresflkkslekkkekeeeldska  120

         +henivnllGact +Gp+y+i+eyccyGdllnylr+kre+f+++++e++ke++++++

Q: 676   NHENIVNLLGACTLSGPVYLIFEYCCYGDLLNYLRNKREKFHRTWTEIFKEHNFSFYPA-  734

         *********************************************************98.

S: 121   lladkslrsksslssesseeyvdlkkdvsdvssskadklasekkksalerevkaaleeed  180

               ++s+ ++s+++s+e v++++d++++s ++ ++++se++ +++++++   +eeed

Q: 735   ------FQSYPNSSMPGSRE-VQIRQDLDHISGFNGNSFQSEDEIEYENQKRL--EEEED  785

         ......9*************.**************************999877..78999

S: 181   sevleledllsfsyqvakGmeflaskncvhrdlaarnvllteGkvvkicdfGlardimkd  240

          +vl++edll+f+yqvakGmefl++k+cvhrdlaarnvl+t+GkvvkicdfGlardim+d

Q: 786   LNVLTFEDLLCFAYQVAKGMEFLEFKSCVHRDLAARNVLVTHGKVVKICDFGLARDIMSD  845

         ************************************************************

S: 241   snyvvkGnarlpvkwmapesifdslytvksdvwsyGillweifslGstpypgllvdskfy  300

         snyv++Gnarlpvkwmapes+f+++yt+ksdvwsyGillweifslG++pypg++vd++fy

Q: 846   SNYVIRGNARLPVKWMAPESLFEGVYTIKSDVWSYGILLWEIFSLGVNPYPGIPVDANFY  905

         ************************************************************

S: 301   klikeGyrmaqpayateeiyeimqkcweaepekrpsfkqlvell  344

         kli++G++m+qp+yateeiy imq+cw+++++krpsf +l+++l

Q: 906   KLIQSGFKMDQPFYATEEIYFIMQSCWAFDSRKRPSFPNLTSFL  949

         ****************************************9986

Domain Sequence
(FASTA)

LEFGKVLGSG AFGKVMNATA YGISQTGVSI QVAVKMLKEK ADSSEREALM SELKMMSHLG 60

NHENIVNLLG ACTLSGPVYL IFEYCCYGDL LNYLRNKREK FHRTWTEIFK EHNFSFYPAF 120

QSYPNSSMPG SREVQIRQDL DHISGFNGNS FQSEDEIEYE NQKRLEEEED LNVLTFEDLL 180

CFAYQVAKGM EFLEFKSCVH RDLAARNVLV THGKVVKICD FGLARDIMSD SNYVIRGNAR 240

LPVKWMAPES LFEGVYTIKS DVWSYGILLW EIFSLGVNPY PGIPVDANFY KLIQSGFKMD 300

QPFYATEEIY FIMQSCWAFD SRKRPSFPNL TSFL 334

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>