EKS-FEC-00385

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-FEC-00385

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TK/PDGFR	611.7	4.1E-184	596	953	358

Status

Unreviewed

Ensembl Protein

ENSFCAP00000008478

Gene Name

PDGFRA

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSFCAG00000009141	ENSFCAP00000008478	ENSFCAT00000009145

Organism

Felis catus

Protein Length

1092

Protein Sequence
(FASTA)

MGTSHLALLV LVCLLTGPSL ISCQLSLPSI LPNENEKVVQ LNSSFSLRCF GESEVSWQYP 60

MSEEENPNVE VRNEENNSGL FVTVLEVVNA SAAHTGLYTC YYNHTQTDEN EIEGRRIYIY 120

VPETTDPDVA FVPLGMTDYL VIVEDDDSAI IPCRTTDPKT PVTLRSSDGV VHASYDSRQG 180

FNGTFSVGPY ICEATVSGKK FQTIPFNVYA LKATSELDLE MEALKTVYKS GETIVVTCAV 240

FNNEVVDLQW TYPGEVKGKG ITMLEEIKVP SIKLVYTLTV PEATVKDSGD YECAARQATK 300

EVKEMKKVTI SVHEKGFIEI KPNFSPLEAV DLHEVKHFVV DVQAYPPPRI SWLKDNLTLI 360

ENLTEITTDI EKIQEVRYRS KLKLIRAKEE DSGHYTIVVQ NEDDVKSYTF ELLTQVPSSI 420

LDLVDDHHGS TGGQTVRCTA EGTPLPDIEW MICKDIKKCN NETSWTVLAN NISNIITEVH 480

RRDRSTVEGR VTFTRVEETI AVRCLAKNLL GAENRELKLV APTLRSELTV AAAVLVLLVI 540

VIISLIVLVV IWKQKPRYEI RWRVIESISP DGHEYIYVDP MQLPYDSRWE FPRDGLVLGR 600

ILGSGAFGKV VEGTAYGLSR SQPVMKVAVK MLKPTARSSE KQALMSELKI MTHLGPHLNI 660

VNLLGACTKS GPIYIITEYC FYGDLVNYLH KNRDSFLSRH PEKPKKELDI FGLNPADEST 720

RSYVILSFEN NGDYMDMKQA DTTQYVPMLE RKEVSKYSDI QRSLYDRPAS YKKKSTSDSE 780

VKNLLSDDNS EGLTLLDLLS FTYQVARGME FLASKNCVHR DLAARNVLLA QGKIVKICDF 840

GLARDIMHDS NYVSKGSTFL PVKWMAPESI FDNLYTTLSD VWSYGILLWE IFSLGGTPYP 900

GMMVDSTFYN KIKNGYRMAK PDHATSEVYE IMVKCWHSEP EKRPSFYHLS EIVENLLPGQ 960

YKKSYEKIHL DFLKSDHPAV ARMRVDSDNA YIGVTYKHEE DKLKDWEGSL DEQRLSADSG 1020

YIIPLPDIDP VPEEEDLGKR NRHSSQTSEE SAIETGSSSS TFVKREDETI EDIDMMDDIG 1080

IDSSDLVEDS FL 1092

Nucleotide Sequence
(FASTA)

ATGGGGACTT CCCACCTGGC GCTCCTGGTG TTAGTCTGTC TCCTCACAGG ACCGAGCCTA 60

ATCTCCTGCC AGCTTTCATT ACCCTCTATC CTTCCAAACG AAAATGAAAA GGTCGTGCAG 120

CTGAATTCCT CCTTTTCTCT GCGATGCTTT GGGGAGAGTG AAGTGAGCTG GCAGTACCCC 180

ATGTCTGAAG AAGAGAACCC CAATGTGGAA GTCAGAAATG AAGAAAACAA CAGTGGCCTT 240

TTTGTGACGG TGCTGGAAGT GGTCAATGCG TCGGCGGCCC ACACGGGACT GTACACTTGC 300

TATTACAACC ACACTCAGAC GGACGAAAAC GAGATCGAAG GCAGGCGCAT TTACATCTAT 360

GTCCCAGAAA CCACAGACCC AGACGTAGCC TTCGTACCTC TAGGAATGAC AGATTATTTA 420

GTTATCGTGG AGGACGATGA CTCTGCCATC ATACCTTGTC GCACAACTGA TCCCAAGACT 480

CCGGTTACCT TACGCAGCAG TGACGGGGTG GTACACGCCT CCTATGACAG CAGACAGGGC 540

TTTAATGGGA CCTTCAGCGT CGGGCCCTAT ATCTGCGAAG CCACAGTCAG CGGGAAGAAG 600

TTCCAGACCA TCCCATTTAA TGTTTACGCT TTAAAAGCAA CATCAGAACT TGATCTTGAA 660

ATGGAAGCTC TCAAAACTGT CTATAAGTCA GGGGAGACGA TTGTGGTCAC CTGCGCCGTC 720

TTTAACAACG AGGTGGTTGA CCTTCAGTGG ACTTACCCTG GAGAAGTGAA AGGCAAAGGC 780

ATCACGATGC TGGAGGAGAT CAAGGTCCCG TCCATCAAAC TGGTTTACAC TCTGACGGTC 840

CCCGAGGCCA CGGTGAAGGA TAGTGGAGAT TATGAATGTG CTGCCCGCCA GGCCACCAAG 900

GAGGTCAAAG AGATGAAGAA AGTCACCATT TCCGTCCATG AGAAAGGGTT CATTGAAATC 960

AAACCCAACT TCAGCCCGTT GGAGGCTGTC GACCTGCATG AAGTCAAACA TTTCGTGGTG 1020

GACGTGCAGG CCTACCCGCC TCCCAGGATA TCCTGGCTGA AGGACAACCT GACTCTGATT 1080

GAAAATCTCA CGGAGATCAC CACCGACATA GAAAAGATCC AGGAAGTAAG GTATCGAAGC 1140

AAATTAAAGC TGATCCGTGC GAAGGAAGAA GACAGTGGCC ATTACACTAT TGTCGTCCAA 1200

AATGAAGACG ATGTGAAGAG CTATACTTTC GAACTCTTAA CGCAAGTTCC TTCGTCTATT 1260

CTGGACTTGG TCGACGACCA CCATGGCTCC ACCGGGGGAC AGACTGTGAG ATGCACAGCA 1320

GAAGGGACAC CTCTTCCCGA TATCGAGTGG ATGATTTGCA AGGATATTAA GAAATGTAAT 1380

AACGAAACTT CATGGACGGT TTTGGCGAAC AACATCTCGA ACATCATCAC GGAGGTCCAC 1440

CGCCGGGACA GGAGTACTGT GGAGGGCCGA GTGACGTTCA CCAGAGTGGA GGAGACCATC 1500

GCCGTTCGAT GCCTGGCCAA GAATCTTCTT GGAGCCGAGA ACCGAGAGCT GAAGCTGGTA 1560

GCTCCCACGC TGCGTTCTGA ACTCACAGTG GCGGCTGCAG TCCTGGTCCT GCTGGTGATT 1620

GTGATCATCT CCCTCATTGT CCTGGTCGTC ATTTGGAAAC AGAAACCGAG GTATGAAATT 1680

CGTTGGAGGG TCATTGAATC GATCAGCCCC GATGGACATG AATATATTTA CGTGGACCCG 1740

ATGCAGCTGC CTTATGACTC TAGATGGGAG TTTCCAAGAG ATGGACTAGT GCTTGGTCGT 1800

ATCCTGGGAT CTGGTGCGTT CGGGAAAGTG GTCGAAGGAA CTGCCTATGG ATTGAGCCGG 1860

TCCCAGCCTG TCATGAAAGT AGCAGTAAAG ATGCTAAAAC CCACAGCCAG ATCCAGTGAA 1920

AAACAAGCTC TCATGTCGGA ACTGAAGATA ATGACTCACC TGGGGCCCCA TTTAAACATT 1980

GTGAACTTGC TGGGGGCCTG CACCAAGTCA GGCCCTATTT ACATCATCAC GGAGTACTGC 2040

TTCTATGGGG ATTTGGTCAA CTATTTGCAT AAGAATAGGG ACAGCTTCCT GAGCCGACAC 2100

CCAGAGAAGC CAAAGAAAGA GTTGGACATT TTTGGGCTGA ACCCTGCTGA TGAAAGCACA 2160

CGGAGTTACG TTATTTTATC TTTTGAAAAC AATGGTGACT ATATGGACAT GAAGCAAGCG 2220

GATACCACAC AGTACGTCCC CATGCTGGAA AGGAAAGAGG TTTCTAAATA CTCGGACATC 2280

CAGAGATCGC TGTATGATCG CCCGGCCTCG TATAAGAAGA AATCTACGTC AGACTCGGAA 2340

GTCAAAAACC TCCTCTCGGA CGATAACTCA GAAGGCCTGA CTCTGCTGGA TTTGTTGAGC 2400

TTTACCTATC AAGTGGCGCG AGGGATGGAA TTTTTGGCTT CCAAAAATTG TGTCCACCGG 2460

GACCTGGCTG CTCGCAACGT CCTCCTGGCG CAAGGGAAAA TCGTGAAGAT CTGTGACTTC 2520

GGCCTGGCCA GGGACATCAT GCACGATTCA AACTACGTGT CCAAAGGCAG CACCTTTCTC 2580

CCCGTGAAGT GGATGGCTCC TGAGAGCATC TTCGACAACC TCTACACCAC GCTGAGTGAC 2640

GTCTGGTCTT ACGGCATTCT GCTCTGGGAG ATCTTTTCCC TTGGGGGCAC CCCGTACCCT 2700

GGCATGATGG TGGATTCCAC TTTCTACAAC AAGATCAAGA ACGGGTACCG GATGGCCAAG 2760

CCTGACCACG CCACCAGCGA AGTCTATGAA ATCATGGTCA AGTGCTGGCA CAGTGAGCCG 2820

GAGAAGAGAC CCTCCTTTTA CCACCTGAGT GAGATTGTGG AGAATCTGTT GCCGGGACAA 2880

TATAAGAAGA GCTACGAAAA GATTCACCTG GACTTCTTGA AGAGCGACCA CCCTGCCGTG 2940

GCGCGCATGC GCGTGGACTC GGACAACGCC TACATCGGCG TCACCTACAA ACACGAGGAA 3000

GACAAGCTGA AGGACTGGGA AGGCAGCCTG GACGAGCAGA GGCTGAGTGC AGACAGCGGC 3060

TACATCATCC CTCTGCCCGA CATCGACCCT GTTCCTGAGG AGGAGGACCT GGGCAAGAGG 3120

AACAGACACA GCTCACAGAC CTCAGAAGAG AGCGCCATTG AGACAGGTTC CAGCAGCTCT 3180

ACCTTTGTCA AGAGAGAGGA TGAAACCATC GAGGACATCG ACATGATGGA TGACATTGGC 3240

ATAGACTCCT CAGACCTGGT AGAGGACAGC TTCCTGTGA 3279

Domain Profile

S: 1     lelGkvlGsGafGkvveatayGlsksdavlkvavkmlkstarssekealmselkilshlG  60

         l+lG++lGsGafGkvve+tayGls+s++v+kvavkmlk+tarssek+almselki++hlG

Q: 596   LVLGRILGSGAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIMTHLG  655

         78**********************************************************

S: 61    ehenivnllGactkgGpiyviteyccyGdllnylrrkresflkkslekkkekeeeldska  120

         +h+nivnllGactk+Gpiy+iteyc+yGdl+nyl+++r+sfl+++ ek   +++eld+++

Q: 656   PHLNIVNLLGACTKSGPIYIITEYCFYGDLVNYLHKNRDSFLSRHPEK---PKKELDIFG  712

         *********************************************999...9999*****

S: 121   l.ladkslrsksslssesseeyvdlkkd................vsdvssskadklasek  163

         l +ad+s+rs+++ls+e++++y+d+k++                +sd+++s +d++as+k

Q: 713   LnPADESTRSYVILSFENNGDYMDMKQAdttqyvpmlerkevskYSDIQRSLYDRPASYK  772

         *9*************************9********************************

S: 164   kksalerevkaaleeedsevleledllsfsyqvakGmeflaskncvhrdlaarnvllteG  223

         kks+ ++evk+ l++++se+l+l dllsf+yqva+Gmeflaskncvhrdlaarnvll++G

Q: 773   KKSTSDSEVKNLLSDDNSEGLTLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQG  832

         ************************************************************

S: 224   kvvkicdfGlardimkdsnyvvkGnarlpvkwmapesifdslytvksdvwsyGillweif  283

         k+vkicdfGlardim+dsnyv+kG+++lpvkwmapesifd+lyt+ sdvwsyGillweif

Q: 833   KIVKICDFGLARDIMHDSNYVSKGSTFLPVKWMAPESIFDNLYTTLSDVWSYGILLWEIF  892

         ************************************************************

S: 284   slGstpypgllvdskfyklikeGyrmaqpayateeiyeimqkcweaepekrpsfkqlvel  343

         slG+tpypg++vds+fy++ik+Gyrma+p++at+e+yeim+kcw++epekrpsf++l+e+

Q: 893   SLGGTPYPGMMVDSTFYNKIKNGYRMAKPDHATSEVYEIMVKCWHSEPEKRPSFYHLSEI  952

         *********************************************************998

S: 344   l  344

Q: 953   V  953

Domain Sequence
(FASTA)

LVLGRILGSG AFGKVVEGTA YGLSRSQPVM KVAVKMLKPT ARSSEKQALM SELKIMTHLG 60

PHLNIVNLLG ACTKSGPIYI ITEYCFYGDL VNYLHKNRDS FLSRHPEKPK KELDIFGLNP 120

ADESTRSYVI LSFENNGDYM DMKQADTTQY VPMLERKEVS KYSDIQRSLY DRPASYKKKS 180

TSDSEVKNLL SDDNSEGLTL LDLLSFTYQV ARGMEFLASK NCVHRDLAAR NVLLAQGKIV 240

KICDFGLARD IMHDSNYVSK GSTFLPVKWM APESIFDNLY TTLSDVWSYG ILLWEIFSLG 300

GTPYPGMMVD STFYNKIKNG YRMAKPDHAT SEVYEIMVKC WHSEPEKRPS FYHLSEIV 358

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>