EKS-FEC-00105

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-FEC-00105

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TK/Tec	472.7	2.2E-142	364	614	251

Status

Unreviewed

Ensembl Protein

ENSFCAP00000009237

Gene Name

ITK

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSFCAG00000009952	ENSFCAP00000009237	ENSFCAT00000009955

Organism

Felis catus

Protein Length

621

Protein Sequence
(FASTA)

MNNFILLEEQ LIKKSQQKRR TSPSNFKVRF FVLTKTSLAY FENRHGGEKR TLKGSIELSR 60

IKCVEIVKSD ISIPCHYKYP FQVVHDNYLL YVFAPDRESR QRWVLALKEE TRNNNSLVPM 120

YHPNFWMDGR WRCCAQLEKL AVGCAQYDPT KNASKKPLPP TPEDNRRSLQ EPEETLVIAL 180

YDYQTNDPQE LTLQRNEEYY LLDSSEIHWW RVQDRNGHEG YVPSSYLVEK SPNSLETYEW 240

YNKSISRDKA EKLLLDTAKE GAFMVRDSRT PGTYTVSVFT KAVVSENNPC IKHYHIKETN 300

DNPKRYYVAE KYVFDSIPLL INYHQHNGGG LVTRLRYPVC SWRQKAPVTA GLRYGKWVID 360

PSELTFVQEI GSGQFGLVHL GYWLNKDKVA IKTIQEGAMS EEDFIEEAEV MMKLSHPKLV 420

QLYGVCLEQA PICLVFEFME HGCLSDYLRN QRGLFAAETL LGMCLDVCEG MAYLEEACVI 480

HRDLAARNCL VGENQVIKVS DFGMTRFVLD DQYTSSTGTK FPVKWASPEV FSFSRYSSKS 540

DVWSFGVLMW EVFSEGKIPY ENRSNSEVVE DISTGFRLYK PRLASSNIYQ IMNHCWKEKP 600

EDRPPFCRLL SQLAEIAESG L 621

Nucleotide Sequence
(FASTA)

ATGAACAACT TTATCCTCCT AGAAGAACAG CTCATCAAGA AATCGCAACA AAAGAGAAGA 60

ACTTCTCCCT CCAACTTTAA AGTCCGCTTC TTTGTTTTAA CCAAAACCAG CCTGGCGTAC 120

TTTGAGAACC GTCATGGGGG AGAAAAGCGC ACATTGAAGG GCTCCATTGA ACTCTCCCGA 180

ATCAAATGTG TTGAGATTGT GAAAAGTGAC ATTAGTATCC CATGCCACTA TAAATATCCA 240

TTTCAGGTTG TGCATGACAA TTACCTCCTG TATGTGTTTG CTCCAGACCG TGAGAGCCGG 300

CAGCGCTGGG TTCTGGCCCT TAAAGAAGAA ACAAGGAACA ATAACAGTTT GGTACCCATG 360

TATCATCCTA ACTTCTGGAT GGATGGGAGG TGGAGGTGCT GTGCTCAGCT GGAGAAGCTC 420

GCAGTGGGCT GTGCCCAGTA CGATCCAACC AAGAATGCTT CAAAGAAGCC TCTTCCTCCT 480

ACTCCTGAAG ACAACAGGCG ATCACTCCAG GAACCTGAAG AAACCCTTGT CATTGCCTTG 540

TATGACTACC AAACGAACGA CCCACAGGAA CTTACGTTAC AACGCAATGA GGAATACTAC 600

CTGCTGGACA GTTCCGAGAT TCACTGGTGG AGAGTGCAGG ACAGGAATGG GCATGAAGGA 660

TATGTACCAA GCAGTTATCT GGTGGAAAAG TCTCCAAATA GCCTGGAAAC CTATGAGTGG 720

TACAATAAGA GCATCAGCCG AGACAAAGCT GAAAAACTTC TTTTGGACAC AGCCAAAGAA 780

GGAGCCTTCA TGGTACGAGA TTCCAGGACT CCAGGAACTT ACACCGTGTC TGTTTTCACT 840

AAAGCCGTTG TAAGTGAGAA CAACCCCTGT ATCAAGCATT ATCACATCAA GGAAACTAAT 900

GATAACCCCA AGCGATATTA TGTGGCTGAA AAGTATGTGT TTGATTCCAT CCCTCTCCTC 960

ATCAATTACC ACCAACACAA TGGAGGAGGT CTGGTCACTC GACTCCGGTA TCCAGTTTGT 1020

TCCTGGAGGC AGAAAGCCCC AGTCACGGCA GGACTGAGAT ATGGGAAATG GGTGATTGAT 1080

CCCTCAGAGC TCACTTTTGT ACAGGAAATT GGCAGTGGGC AGTTTGGGTT GGTGCATCTT 1140

GGCTACTGGC TCAACAAGGA CAAGGTGGCC ATCAAAACCA TTCAAGAAGG GGCTATGTCC 1200

GAAGAGGACT TCATAGAGGA GGCTGAAGTC ATGATGAAAC TCTCTCACCC CAAACTGGTG 1260

CAGCTGTATG GGGTATGCCT AGAGCAGGCC CCCATCTGCC TGGTGTTTGA GTTCATGGAA 1320

CACGGCTGCC TGTCGGATTA CCTGCGCAAC CAGCGAGGAC TCTTTGCTGC AGAAACCTTG 1380

CTGGGCATGT GCCTGGACGT GTGTGAGGGC ATGGCCTACC TGGAAGAGGC ATGTGTCATC 1440

CACAGAGACC TGGCTGCCAG AAATTGTTTA GTGGGAGAAA ACCAAGTCAT CAAGGTGTCC 1500

GACTTTGGGA TGACAAGGTT CGTCCTTGAT GATCAATACA CCAGTTCCAC AGGCACCAAG 1560

TTCCCAGTGA AGTGGGCATC CCCGGAAGTC TTCTCCTTCA GTCGCTATAG CAGCAAGTCA 1620

GATGTGTGGT CATTTGGTGT GCTGATGTGG GAAGTCTTCA GTGAAGGCAA AATCCCGTAT 1680

GAAAACCGAA GCAACTCAGA GGTGGTGGAA GATATCTCTA CTGGATTTCG CTTATACAAG 1740

CCCCGGCTGG CCTCCTCAAA TATCTACCAG ATCATGAATC ATTGCTGGAA AGAGAAACCA 1800

GAAGACCGGC CACCTTTCTG CAGACTCTTG AGTCAACTGG CTGAAATTGC AGAATCAGGA 1860

CTTTAG 1866

Domain Profile

S: 1     ltllkelgsgqfgvvklgkwrakidvaikaikegamseedfieeakvmmklshpklvqly  60

         lt+++e+gsgqfg+v+lg+w +k++vaik+i+egamseedfieea+vmmklshpklvqly

Q: 364   LTFVQEIGSGQFGLVHLGYWLNKDKVAIKTIQEGAMSEEDFIEEAEVMMKLSHPKLVQLY  423

         79**********************************************************

S: 61    gvclkqkpiyivteylengcllnylrekkkklekelllemckdvcegmeylerksfihrd  120

         gvcl+q+pi++v+e++e+gcl++ylr++++ +++e+ll mc dvcegm+yle++++ihrd

Q: 424   GVCLEQAPICLVFEFMEHGCLSDYLRNQRGLFAAETLLGMCLDVCEGMAYLEEACVIHRD  483

         ************************************************************

S: 121   laarnclvdeelvvkvsdfglaryvlddqyvssvgakfpvkwsppevlsyskyssksdvw  180

         laarnclv+e++v+kvsdfg++r+vlddqy+ss+g+kfpvkw++pev+s+s+yssksdvw

Q: 484   LAARNCLVGENQVIKVSDFGMTRFVLDDQYTSSTGTKFPVKWASPEVFSFSRYSSKSDVW  543

         ************************************************************

S: 181   afgvlmwevfsegklpyekksnsevvekvsrglrlyrpklaskkvyevmkscwkekpeer  240

         +fgvlmwevfsegk+pye++snsevve++s+g+rly+p+las+++y++m++cwkekpe+r

Q: 544   SFGVLMWEVFSEGKIPYENRSNSEVVEDISTGFRLYKPRLASSNIYQIMNHCWKEKPEDR  603

         ************************************************************

S: 241   ptfkellsale  251

         p f +lls+l+

Q: 604   PPFCRLLSQLA  614

         ********986

Domain Sequence
(FASTA)

LTFVQEIGSG QFGLVHLGYW LNKDKVAIKT IQEGAMSEED FIEEAEVMMK LSHPKLVQLY 60

GVCLEQAPIC LVFEFMEHGC LSDYLRNQRG LFAAETLLGM CLDVCEGMAY LEEACVIHRD 120

LAARNCLVGE NQVIKVSDFG MTRFVLDDQY TSSTGTKFPV KWASPEVFSF SRYSSKSDVW 180

SFGVLMWEVF SEGKIPYENR SNSEVVEDIS TGFRLYKPRL ASSNIYQIMN HCWKEKPEDR 240

PPFCRLLSQL A 251

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dasypus novemcinctus"; ?>Equus caballus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>