EPS-FEC-00034

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-FEC-00034

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	191.5	2.3E-56	776	1022	247

Status

Unreviewed

Ensembl Protein

ENSFCAP00000011041

Gene Name

PHLPP2

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSFCAG00000011901	ENSFCAP00000011041	ENSFCAT00000011904

Organism

Felis catus

Protein Length

1314

Protein Sequence
(FASTA)

MKRNGSRTCL NRRSRFGSRE RDWLREDVKR GCVYLYGADT TTASTTASAS SDLHLVLCTV 60

ETPASEICAG EGRESLYLQL HGDLVRRLEP TERPLQIVYD YLARLGFDDP VRIQEEATDP 120

DLGCMLRFYG EKPCQMDHLD RILLSGIYNV RKGKTQLHKW AERLVVLCGT CLIVSSVKDC 180

QTGKMHILPL VGGKVEEVKR RQHSLAFSSA GAQAQTYHVS FETLAECQRW QRQASKVVSQ 240

RISTVDLSCY SLEEVPEHLF YSQDITYLNL RHNFMQLERP GGLDTLYRFS QLKGLNLSHN 300

KLGLFPVLLC EISTLTELNL SCNGFHDLPS QIGNLLNLQT LCVDGNFLTT LPEELGNLQQ 360

LSSLGISFNN FSHIPEVYEK LTMLDKVVMA GNHLEVLNLG VLNRMSHIKH VDLRMNHLKT 420

VVTENLEGNK YITHMDLRDN QLADLDLNSL CSLEQLHCER NQLRELTLSG FSLRTLYASS 480

NRLTAVNVYP VPSQLTSLEL SRNLLECVPD WACEAKKMEI LDVSCNLLTE VPMRILSSLS 540

LRKLMLGHNQ VQSLPALVDH IPLEVLDIQH NLLTRLPDTL FSKALNLRYL NASANSLESL 600

PSAGTGEESL SALQLLYLTN NLLTDQCVPV LVGHPHLRIL HLANNQLQTF PASKLNKLEQ 660

LEELNLSGNK LKTIPTTIAN CRRLHTLVAH SNNISIFPEI LQLPQIQFVD LSCNDLTEIL 720

IPEALPATLQ DLDLTGNTNL VLEHKTLDTF SHITTLKIDQ KPLPTTDSTV TSTFWSHGLA 780

EMAGQRNKLC VSALAVDNFA EGVGAVYGMF DGDRNEELPR LLQCTMADVL LEEVQQSTND 840

TVFMANTFLV SHRKLGMAGQ KLGSSALLCY IRPDTADPTS SFSLTVANVG TCQAVLCRGG 900

KPVPLSKVFS LEQDPEEAQR VKDQKAIITE DNKVNGVTCC TRMLGCTYLY PWILPKPHIS 960

ATPLTIQDEL LILGNKALWE HLSYTEAVNA VRHVQDPLAA AKKLCTLAQS YGCQDNVGAM 1020

VVYLNIGEEG CTCEMNGLTL PGPVGFASTT IIKDPPKPTT PSSSSGIASE FGSEMSTSEV 1080

SSEVGSTASD EHNTVGLDAG LLPRPERRCS LHPTPTSGVF QRQPSCATFS SNQSDNGLDS 1140

DDDQPVEGVI TNGSKVEVEV DIHCCRGRDL ENSPTLTENS HTPCPEEHAR GSFFGIRRQN 1200

SVNSGILLPV SKDKMELQKS PSTSCLYGKK LSNGSIVPLE DSLNLIEVAT EAPKKKTGYF 1260

AAPTQLEPED QFVVPRDLEE EVKEQMKQHQ EGRPEPEPSE EDRTELPEEF DTAL 1314

Nucleotide Sequence
(FASTA)

ATGAAACGCA ATGGGAGCAG AACTTGTTTG AATAGGAGAA GTAGGTTTGG TTCTCGAGAA 60

AGAGACTGGC TGAGAGAAGA TGTGAAGAGA GGTTGTGTTT ACCTTTATGG AGCAGACACG 120

ACCACTGCCT CTACAACCGC CTCTGCCTCC TCTGACTTAC ATCTCGTCCT GTGTACAGTG 180

GAGACCCCCG CGTCGGAAAT CTGTGCTGGA GAGGGAAGGG AAAGTCTGTA TCTACAGCTT 240

CATGGGGACC TAGTCAGGCG ACTGGAACCT ACTGAACGAC CTCTTCAGAT TGTTTATGAT 300

TACTTAGCCA GGCTGGGATT TGACGACCCT GTGCGCATAC AGGAGGAGGC AACAGATCCT 360

GACCTTGGCT GTATGCTTCG ATTTTATGGT GAAAAACCAT GCCAGATGGA TCATCTGGAT 420

CGAATCCTTC TGTCTGGTAT CTATAATGTA CGCAAGGGAA AGACCCAGCT GCATAAGTGG 480

GCTGAACGCC TAGTTGTTCT CTGTGGTACC TGCCTCATCG TTTCCTCAGT AAAAGATTGT 540

CAAACTGGAA AGATGCACAT TTTGCCTTTG GTTGGGGGAA AGGTGGAAGA AGTGAAGCGA 600

CGGCAGCACT CCCTTGCATT CAGCTCAGCT GGAGCCCAGG CTCAGACCTA TCATGTCAGC 660

TTTGAGACAT TGGCTGAGTG CCAGAGATGG CAGCGACAAG CGTCCAAGGT GGTGTCCCAG 720

CGAATCAGCA CCGTCGACCT CTCGTGTTAC AGCCTTGAGG AGGTTCCTGA GCATCTCTTC 780

TATAGTCAAG ATATCACCTA CCTCAACTTG CGACACAACT TCATGCAGCT GGAAAGACCA 840

GGGGGCCTTG ACACTCTCTA CAGATTTTCT CAGCTGAAGG GCCTGAACTT GTCCCACAAT 900

AAACTTGGGT TGTTTCCTGT ATTGTTATGT GAGATTTCTA CCCTGACTGA GCTCAACCTC 960

TCCTGTAATG GATTTCATGA CCTACCAAGT CAGATTGGCA ATCTGCTAAA TCTTCAAACC 1020

CTCTGTGTTG ATGGCAACTT TCTGACAACT TTACCTGAGG AACTGGGAAA TCTGCAACAG 1080

CTTTCTTCCC TGGGAATTTC CTTCAACAAC TTTAGTCATA TTCCTGAGGT TTATGAGAAA 1140

CTCACTATGT TAGATAAAGT AGTTATGGCG GGAAATCACC TGGAAGTCCT AAACCTTGGG 1200

GTGCTGAATA GGATGAGCCA TATCAAACAT GTGGATTTAA GGATGAACCA TTTGAAAACT 1260

GTAGTTACTG AAAATCTGGA GGGAAATAAA TACATCACCC ACATGGATTT GCGGGACAAT 1320

CAACTGGCTG ACTTAGATCT CAACTCCTTA TGTAGCTTGG AGCAGCTGCA TTGTGAGCGG 1380

AACCAACTGA GAGAGCTGAC ACTCAGTGGC TTCTCCCTTC GAACTCTGTA CGCCAGTTCG 1440

AACAGGCTGA CAGCAGTGAA TGTCTATCCA GTACCCAGTC AACTCACTTC TCTAGAACTT 1500

TCCCGAAACC TGCTGGAGTG TGTCCCTGAT TGGGCCTGTG AAGCAAAGAA GATGGAGATA 1560

CTAGATGTGA GCTGTAATCT TCTGACGGAG GTTCCCATGA GAATTCTTAG TAGCTTGAGT 1620

CTTAGAAAAC TGATGCTGGG GCACAACCAG GTACAGAGCC TGCCAGCCCT GGTGGACCAC 1680

ATCCCTCTTG AGGTGCTGGA TATTCAGCAT AACTTACTCA CCAGGCTGCC AGATACTCTC 1740

TTCTCCAAGG CCTTAAATCT CAGATACTTG AATGCATCTG CAAACAGTTT GGAATCTTTG 1800

CCATCCGCTG GCACTGGAGA GGAGAGTCTG AGTGCTCTGC AGCTGCTTTA TCTGACGAAC 1860

AACCTCCTGA CAGACCAGTG TGTGCCCGTT CTGGTGGGGC ATCCACACCT GCGAATCTTG 1920

CATCTTGCAA ACAACCAGCT ACAGACCTTT CCTGCAAGCA AACTGAATAA ATTGGAGCAG 1980

TTGGAAGAAC TGAACCTAAG TGGCAACAAG CTTAAAACCA TTCCCACGAC CATAGCCAAC 2040

TGCAGAAGGC TTCACACCCT TGTCGCACAC TCTAACAACA TCAGCATTTT CCCAGAAATT 2100

CTGCAGTTGC CTCAGATCCA GTTTGTAGAC CTAAGTTGCA ATGACTTGAC AGAGATCTTG 2160

ATTCCGGAGG CTCTGCCTGC TACTTTACAA GACCTTGACC TGACCGGAAA TACAAATCTG 2220

GTTCTGGAAC ACAAGACGCT GGACACATTT AGCCATATCA CAACCCTGAA AATTGATCAG 2280

AAACCTTTGC CAACCACCGA TTCTACAGTT ACATCAACCT TCTGGAGCCA TGGACTGGCT 2340

GAGATGGCAG GGCAGAGAAA TAAGCTGTGT GTATCTGCCC TAGCTGTGGA TAACTTTGCA 2400

GAGGGGGTGG GAGCCGTGTA TGGCATGTTT GACGGGGACC GTAATGAGGA GCTCCCTCGC 2460

CTACTCCAGT GCACCATGGC AGATGTGCTT TTGGAAGAAG TACAGCAGTC AACAAATGAC 2520

ACTGTTTTCA TGGCTAACAC CTTCTTGGTA TCTCACAGAA AATTGGGAAT GGCTGGACAG 2580

AAGCTGGGCT CCTCCGCTCT CCTTTGTTAT ATCCGCCCTG ACACTGCTGA CCCAACAAGT 2640

AGTTTCAGTC TGACTGTGGC CAACGTCGGC ACGTGCCAAG CAGTCCTGTG CCGTGGTGGA 2700

AAGCCAGTGC CACTCTCAAA AGTCTTCAGC CTGGAACAGG ACCCGGAGGA GGCTCAAAGG 2760

GTGAAGGACC AGAAAGCCAT CATAACAGAG GACAACAAAG TGAATGGGGT AACCTGCTGT 2820

ACCCGGATGC TGGGCTGTAC ATACCTCTAC CCTTGGATCC TCCCCAAGCC CCACATATCT 2880

GCCACTCCAC TTACCATTCA AGATGAGTTG CTGATTCTGG GAAACAAAGC ATTGTGGGAA 2940

CACTTGTCAT ATACGGAAGC TGTCAACGCA GTACGCCACG TGCAGGACCC ATTAGCAGCT 3000

GCCAAGAAGC TGTGCACATT AGCCCAGAGC TATGGTTGTC AGGACAATGT GGGGGCAATG 3060

GTGGTTTATT TGAACATTGG TGAGGAAGGG TGCACGTGTG AAATGAATGG GCTCACCCTC 3120

CCAGGTCCTG TGGGGTTTGC TTCAACCACC ATTATCAAAG ACCCCCCCAA ACCAACCACT 3180

CCTTCCTCCA GTAGTGGTAT TGCCTCTGAG TTTGGCAGCG AGATGTCCAC TTCAGAGGTG 3240

AGCAGTGAGG TGGGGTCCAC TGCTTCTGAT GAACACAACA CTGTTGGCCT GGATGCTGGC 3300

TTGCTTCCAA GGCCAGAAAG GCGCTGCAGC CTTCATCCAA CACCCACCTC TGGGGTTTTT 3360

CAGCGCCAGC CTTCTTGTGC GACTTTCTCA AGTAACCAGT CTGACAATGG CCTGGACAGT 3420

GATGACGACC AGCCTGTGGA GGGAGTCATA ACAAATGGCA GCAAGGTAGA AGTAGAAGTA 3480

GATATCCACT GCTGCAGGGG AAGGGATCTT GAGAACTCCC CCACTCTTAC AGAGAATTCT 3540

CATACCCCGT GTCCCGAAGA ACATGCTAGA GGATCATTTT TTGGGATCCG AAGACAGAAC 3600

AGTGTGAACA GTGGCATACT TCTGCCAGTG AGCAAGGACA AGATGGAGTT GCAGAAGTCC 3660

CCCTCTACTT CCTGCCTCTA TGGAAAGAAA CTCTCCAACG GCTCTATTGT GCCCCTAGAA 3720

GATAGCCTGA ACCTCATTGA GGTGGCCACA GAAGCACCCA AGAAGAAGAC TGGCTATTTT 3780

GCTGCCCCGA CGCAGCTGGA GCCAGAGGAT CAGTTTGTTG TTCCTCGTGA CCTGGAAGAA 3840

GAAGTGAAGG AGCAGATGAA ACAGCACCAG GAAGGCAGGC CGGAGCCTGA GCCCAGCGAA 3900

GAGGATCGGA CCGAGCTCCC GGAGGAGTTT GACACAGCAC TGTAA 3945

Domain Profile

S: 2     lvgvvsvngrrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheil  61

         ++g++++ g+rn+++ ++ +++nf++  +     a++g++DG++++e  + +++++ ++l

Q: 776   SHGLAEMAGQRNKLCVSALAVDNFAEGVG-----AVYGMFDGDRNEELPRLLQCTMADVL  830

         6899*********************9877.....59************************

S: 62    aeelesseseerkvkkalakaFlstdeelkvleeksldidksGstavvalikds......  115

          ee++    ++++ + ++a++Fl  +++l       ++ +k Gs+a++++i+++

Q: 831   LEEVQ----QSTNDTVFMANTFLVSHRKL------GMAGQKLGSSALLCYIRPDtadpts  880

         ***99....77888889************......89***************999999**

S: 116   ..klyvanvGdSravLcrngkavelssdHkpsre.dEleRieeaggsvilkdgaRvlGvL  172

           +l+vanvG ++avLcr+gk+v+ls+ ++ +++ +E +R++++++ +++++  +v+Gv+

Q: 881   sfSLTVANVGTCQAVLCRGGKPVPLSKVFSLEQDpEEAQRVKDQKAIITEDN--KVNGVT  938

         ******************************99866**********9999998..******

S: 173   avsRalGdlylkpyvtpePevtshrltsedefliLasDGlwdvvsneeavslvrdvlekk  232

         +++R+lG++yl+p++ p+P+++ ++lt +de liL+ + lw+++s  eav++vr+v +

Q: 939   CCTRMLGCTYLYPWILPKPHISATPLTIQDELLILGNKALWEHLSYTEAVNAVRHVQD--  996

         **********************************************************..

S: 233   eaeqeaakkLvklalargskdnvsaivv  260

           + +aakkL++la+++g++dnv a+vv

Q: 997   --PLAAAKKLCTLAQSYGCQDNVGAMVV  1022

         ..************************97

Domain Sequence
(FASTA)

SHGLAEMAGQ RNKLCVSALA VDNFAEGVGA VYGMFDGDRN EELPRLLQCT MADVLLEEVQ 60

QSTNDTVFMA NTFLVSHRKL GMAGQKLGSS ALLCYIRPDT ADPTSSFSLT VANVGTCQAV 120

LCRGGKPVPL SKVFSLEQDP EEAQRVKDQK AIITEDNKVN GVTCCTRMLG CTYLYPWILP 180

KPHISATPLT IQDELLILGN KALWEHLSYT EAVNAVRHVQ DPLAAAKKLC TLAQSYGCQD 240

NVGAMVV 247

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>