EKS-FEC-00449

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-FEC-00449

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/MAPK	335.5	2.3E-100	22	312	291

Status

Unreviewed

Ensembl Protein

ENSFCAP00000011277

Gene Name

MAPK4

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSFCAG00000012154	ENSFCAP00000011277	ENSFCAT00000012157

Organism

Felis catus

Protein Length

588

Protein Sequence
(FASTA)

MAEKGDCIAS VYGYDLGGRF VDFQPLGFGV NGLVLSAVDS RACRKVAVKK ITLSDSRSMK 60

HALREIKIIR RLDHDNIVKV YEVLGPKGTD LQGELFKFSV AYIVQEYMET DLARLLEQGT 120

LTEEHAKLFM YQLLRGLKYI HSANVLHRDL KPANIFISTE DLVLKIGDFG LARIVDQHYS 180

HKGYLSEGLV TKWYRSPRLL LSPNNYTKAI DMWAAGCILA EMLTGRMLFA GAHELEQMQL 240

ILETIPVIRE EDKDELLKVM PSFVSSTWEV KRPLRKLLPE VNSEAIDFLE KILTFNPMDR 300

LTAEMGLQHP YMSPYSCPED EPTSQHPFRI EDEIDDILLM AANQSQLSNW DRCSSRGYPV 360

SLSSDLEWRP DRCQDASEVQ RDPRAGSAPL AEDVQVDPRK DSQSSSERFL ERSHSSMERA 420

FEADCGRSCD YKVGSPSYLD KLLWRDNKPH HYSEPKLILD LSHWKQAAGA PPSAAVAADA 480

GPREDEPASL FLEIAQWVKS TQVGPERASP PPDSPERRLS ASPPGHPAPI DGGGSPQFDL 540

DVFISRALKL CTNPEDLPDN KLGDLNGGCI SEHPGDLVQT EAFSKERW 588

Nucleotide Sequence
(FASTA)

ATGGCCGAGA AGGGCGACTG CATCGCCAGT GTCTATGGGT ATGACCTTGG TGGGCGCTTC 60

GTTGACTTCC AACCCCTGGG TTTTGGTGTC AATGGGCTGG TGCTGTCAGC TGTGGACAGC 120

AGGGCCTGCC GGAAGGTGGC TGTGAAGAAG ATCACCCTGA GTGACTCCCG CAGCATGAAG 180

CATGCGCTCC GGGAGATCAA GATCATCCGG CGCCTGGACC ATGACAACAT CGTGAAGGTG 240

TATGAGGTGC TGGGGCCCAA GGGCACTGAC CTGCAGGGCG AGCTGTTCAA GTTCAGCGTG 300

GCCTACATTG TCCAGGAGTA CATGGAGACC GACCTGGCAC GCCTGTTGGA GCAAGGCACG 360

CTGACAGAGG AACACGCAAA GCTGTTCATG TACCAGCTGC TCCGAGGGCT CAAGTACATC 420

CACTCCGCCA ACGTGCTGCA CAGGGACCTG AAGCCCGCCA ACATCTTCAT TAGCACGGAG 480

GACCTCGTGC TCAAGATCGG GGATTTCGGG TTGGCGAGGA TCGTTGACCA GCATTATTCA 540

CACAAGGGCT ATCTGTCGGA AGGGTTGGTA ACTAAGTGGT ACCGCTCACC ACGCCTGCTC 600

CTCTCCCCGA ACAACTACAC CAAAGCCATT GACATGTGGG CCGCCGGCTG CATCCTGGCC 660

GAGATGCTCA CGGGGAGAAT GCTCTTTGCC GGGGCCCACG AGCTGGAGCA GATGCAGCTC 720

ATCCTGGAGA CCATCCCCGT GATCCGGGAG GAGGACAAAG ACGAGCTGCT CAAGGTGATG 780

CCTTCCTTCG TCAGCAGCAC CTGGGAGGTG AAGCGGCCGC TGCGCAAGCT GCTGCCCGAA 840

GTGAACAGCG AAGCCATTGA CTTTCTGGAG AAGATCCTGA CCTTTAACCC CATGGATCGC 900

CTAACAGCAG AGATGGGGCT GCAGCATCCC TACATGAGCC CATACTCGTG CCCCGAGGAC 960

GAGCCCACCT CACAGCACCC CTTCCGCATC GAAGATGAGA TCGACGACAT CCTGCTGATG 1020

GCCGCCAACC AGAGCCAGCT CTCCAACTGG GACAGGTGCA GTTCCAGAGG GTACCCTGTG 1080

AGCCTGTCAT CGGACCTGGA GTGGAGGCCG GACAGATGTC AGGACGCCAG CGAGGTACAG 1140

CGCGACCCGC GCGCGGGCTC CGCGCCGCTG GCTGAGGACG TGCAGGTGGA TCCGCGCAAG 1200

GACTCGCAGA GCAGCTCCGA GCGCTTTCTG GAGCGCTCGC ACTCGTCCAT GGAGCGCGCC 1260

TTCGAGGCCG ACTGCGGCCG CTCCTGCGAC TACAAAGTGG GCTCGCCGTC CTACCTGGAT 1320

AAGCTGCTGT GGCGCGACAA CAAGCCGCAC CACTACTCGG AGCCCAAGCT CATTCTGGAC 1380

CTGTCGCACT GGAAGCAGGC GGCCGGGGCG CCCCCCAGTG CCGCGGTGGC CGCAGACGCC 1440

GGGCCACGCG AAGACGAGCC GGCCAGCCTC TTCCTGGAGA TCGCGCAGTG GGTCAAGAGC 1500

ACGCAGGTGG GCCCCGAGCG CGCCAGCCCA CCCCCCGACA GCCCCGAGCG CCGCCTGTCT 1560

GCCTCTCCAC CGGGCCACCC CGCACCCATC GACGGGGGCG GGAGCCCCCA GTTCGACCTG 1620

GACGTGTTCA TCTCCCGCGC CCTGAAGCTC TGCACCAACC CGGAGGACCT GCCAGACAAT 1680

AAACTGGGTG ACCTCAATGG TGGGTGCATC TCTGAGCACC CTGGCGATCT TGTGCAGACA 1740

GAGGCCTTCT CCAAAGAAAG GTGGTGA 1767

Domain Profile

S: 3     slkplgeGaygvvvsavdkrteervaikklsrpfqketsakrtlRElkllkelkheNiik  62

         + +plg G +g+v+savd+r+ ++va+kk++  ++++ s+k++lRE+k++++l+h+Ni+k

Q: 22    DFQPLGFGVNGLVLSAVDSRACRKVAVKKIT--LSDSRSMKHALREIKIIRRLDHDNIVK  79

         6799**************************9..9**************************

S: 63    lldvftpee.....eleelkdvYlvtelmetdLkkviksqklsdehiklllyqilrglky  117

         +++v+ p+      el +++  Y+v+e+metdL++++++ +l++eh+kl++yq+lrglky

Q: 80    VYEVLGPKGtdlqgELFKFSVAYIVQEYMETDLARLLEQGTLTEEHAKLFMYQLLRGLKY  139

         *******9888888899*******************************************

S: 118   lHsanviHrDlKPsNllvnedc.elkildFGlarsadkekekk..lteyvatrwYraPei  174

         +Hsanv+HrDlKP+N++++++   lki dFGlar+ d+++++k  l+e ++t+wYr+P++

Q: 140   IHSANVLHRDLKPANIFISTEDlVLKIGDFGLARIVDQHYSHKgyLSEGLVTKWYRSPRL  199

         ******************8765169**************999999***************

S: 175   llslkeytkavDiWsvGCIlaElltgkplfpgkdeidqlekilevlgtpseeflkkiese  234

         lls ++ytka+D+W++GCIlaE+ltg++lf+g++e++q+++ile+++  +ee+ +++ +

Q: 200   LLSPNNYTKAIDMWAAGCILAEMLTGRMLFAGAHELEQMQLILETIPVIREEDKDELLKV  259

         **********************************************************95

S: 235   earnyikslpkkkkkdfeelfpkaseealdLleklLvldpdkRisveeaLehpYl  289

          + ++++s+++ k+ ++++l+p+ ++ea+d+lek+L+++p++R+++e+ L+hpY+

Q: 260   -MPSFVSSTWEVKR-PLRKLLPEVNSEAIDFLEKILTFNPMDRLTAEMGLQHPYM  312

         .9*******99988.9**************************************7

Domain Sequence
(FASTA)

DFQPLGFGVN GLVLSAVDSR ACRKVAVKKI TLSDSRSMKH ALREIKIIRR LDHDNIVKVY 60

EVLGPKGTDL QGELFKFSVA YIVQEYMETD LARLLEQGTL TEEHAKLFMY QLLRGLKYIH 120

SANVLHRDLK PANIFISTED LVLKIGDFGL ARIVDQHYSH KGYLSEGLVT KWYRSPRLLL 180

SPNNYTKAID MWAAGCILAE MLTGRMLFAG AHELEQMQLI LETIPVIREE DKDELLKVMP 240

SFVSSTWEVK RPLRKLLPEV NSEAIDFLEK ILTFNPMDRL TAEMGLQHPY M 291

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>