EPS-FEC-00030

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-FEC-00030

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	209.0	9.9E-62	663	908	246

Status

Unreviewed

Ensembl Protein

ENSFCAP00000015879

Gene Name

PHLPP1

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSFCAG00000018908	ENSFCAP00000015879	ENSFCAT00000018904

Organism

Felis catus

Protein Length

1070

Protein Sequence
(FASTA)

MDSEIGCLIR FYAGKPHSTG GSERIQLSGM YNVRKGKMQL PVNRWARRQV ILCGTCLMVS 60

SVKDSWAGKM HVLPLIGGKV EEVKKHQHCL AFSSSGPQSQ TYYICFDTFT EYLRWLRQVS 120

KVASQRISSV DLSCCSLEHL PANLFYSQDL THLNLKQNFL RQNPCLPTAR GLNELQRFTK 180

LKSLNLSNNH LGEFPLAVCS IPTLTELNVS CNALRAVPAA VRVMHNLQTF LLDGNFLQAL 240

PPELENMHQL SYLGLSFNEF TDIPEVLEKL TAVDKLCMSG NCMETLRLQA LRRMPHIKHV 300

DLRLNIIRKL IADEVDFLQH VTQLDLRDNK LGDLDAMIFN NIEVLHCERN QLVTLNICGY 360

FLKALYASSN ELVQLDVYPV PNYLSYMDVS RNCLENVPEW VCESRKLEVL DISHNQICEL 420

PARLFCNGAL RKLLAGHNEL TRLPERLERT SVEVLDVQHN QLLELPPNLL MKADSLRFLN 480

ASANKLETLP PATLSEETSS ILQELYLTNN SLTDKCVPLL TGHPRLKILH MAYNRLQSFP 540

ASKMAKLEEL EEIDVSGNKL KAIPTTVMNC RRMHTVIAHS NCIEVFPEVM QLPEIKCVDL 600

SCNELSEVTL PENLPPKLQE LDLTGNPRLA LDHKTLELLN NIRCFKIDQP SAGDGSGAPA 660

VWSHGYTEAS GVKNKLCVAA LSVNNFCDNR EALYGVFDGD RNVEVPYLLQ CTMSDILAEE 720

LQKTKNEEEY MVNTFIVMQR KLGTAGQKLG GAAVLCHIKH DPMDPGGSFT LTSANVGKCQ 780

TVLCRNGKPL PLSRSYVMSC EEELKRIKRH KAIITEDGKV NGVTESTRIL GYTFLHPSVV 840

PRPHVQSVPL TPQDEFFILG SKGLWDSLSA EEAVAAVRNV PDALAAAKKL CTLAQSYGCR 900

DSLSAVVVQL SVAEDGFCCC ELGAGGAGPP PSPGIFPPAA SMATRDRPAD ALGVPSSSSG 960

MASEMSSELS TSEMSSEVGS TASDEPPPGA PAESSPAYAS EPRCALHPVG LAHAFQRQLS 1020

SATFSSAFSD NGLDSDDEEP IEGVFTNGSR VEVEVDIHCG RAREKERRRP 1070

Nucleotide Sequence
(FASTA)

ATGGACTCGG AGATTGGCTG CCTCATCCGC TTCTATGCAG GAAAACCCCA CAGCACTGGT 60

GGCTCTGAAC GGATTCAGCT CTCAGGAATG TATAACGTCC GTAAAGGCAA AATGCAGTTG 120

CCGGTGAACC GATGGGCCAG ACGCCAAGTC ATCCTGTGTG GGACCTGCCT GATGGTGTCA 180

TCTGTGAAAG ACAGCTGGGC CGGAAAGATG CATGTTCTGC CTCTCATTGG TGGAAAAGTA 240

GAAGAAGTGA AAAAGCACCA GCACTGTTTA GCATTTAGCT CCTCTGGACC CCAAAGCCAG 300

ACTTACTACA TTTGTTTTGA TACATTCACA GAGTATTTAA GGTGGCTTCG ACAAGTCTCC 360

AAGGTGGCTT CACAGCGCAT TAGCTCAGTG GACCTCTCGT GCTGTAGCCT GGAGCACCTG 420

CCTGCCAACC TCTTCTACAG CCAGGACCTC ACGCACCTCA ACTTAAAACA AAACTTCCTA 480

AGGCAAAATC CCTGCCTGCC AACTGCCAGG GGGCTCAATG AACTGCAAAG GTTCACCAAG 540

TTGAAGAGTC TTAACCTTTC CAATAATCAC TTAGGGGAAT TCCCATTAGC TGTCTGCAGT 600

ATTCCAACCC TGACTGAGTT GAATGTGTCC TGCAACGCCC TTCGAGCAGT CCCAGCGGCC 660

GTCCGAGTTA TGCACAACCT GCAGACATTT TTGTTGGATG GAAACTTTCT CCAGGCCCTT 720

CCTCCTGAGT TGGAGAACAT GCACCAGCTC AGTTATCTTG GTCTTTCTTT TAATGAATTC 780

ACTGACATTC CAGAGGTTTT GGAGAAATTG ACTGCTGTGG ATAAACTTTG TATGTCTGGA 840

AACTGTATGG AAACCCTGCG GCTCCAGGCT TTAAGAAGAA TGCCTCACAT TAAACATGTG 900

GATCTGAGAC TGAACATAAT TAGGAAGCTA ATAGCAGACG AAGTGGACTT TCTCCAGCAC 960

GTCACTCAGC TTGATCTGCG CGACAATAAG CTTGGTGACC TCGATGCTAT GATTTTCAAC 1020

AACATTGAAG TTTTGCACTG TGAAAGGAAT CAGCTGGTGA CATTAAACAT CTGTGGCTAC 1080

TTCCTAAAAG CACTCTACGC CTCTTCTAAC GAACTTGTAC AACTGGATGT TTACCCAGTT 1140

CCAAATTATC TGTCCTACAT GGACGTTTCA AGGAACTGCT TAGAAAACGT GCCTGAGTGG 1200

GTATGCGAAA GCCGAAAGCT GGAAGTTTTG GATATTAGTC ATAATCAAAT ATGCGAACTT 1260

CCTGCACGCT TATTTTGTAA CGGCGCTCTC CGGAAGCTCC TGGCGGGACA CAACGAGCTG 1320

ACGAGGCTCC CTGAGAGGCT GGAAAGGACC TCGGTGGAGG TCTTGGATGT ACAGCACAAC 1380

CAGCTCCTGG AGCTGCCGCC GAACCTTCTG ATGAAGGCCG ACAGCCTGAG ATTCCTGAAT 1440

GCGTCTGCCA ACAAACTGGA AACCCTTCCG CCAGCCACTC TGTCGGAAGA GACGAGCAGC 1500

ATCCTGCAGG AGTTGTATTT GACAAATAAC AGCCTCACAG ATAAATGTGT GCCCTTGTTA 1560

ACAGGACACC CCCGCCTAAA GATCCTTCAC ATGGCCTATA ACCGACTTCA GAGTTTTCCA 1620

GCAAGTAAAA TGGCAAAACT GGAGGAACTT GAAGAAATTG ATGTCAGTGG GAATAAACTG 1680

AAAGCCATCC CGACCACTGT CATGAATTGC AGGCGTATGC ACACCGTGAT TGCACATTCT 1740

AATTGCATCG AAGTCTTTCC TGAAGTGATG CAGCTCCCAG AAATCAAGTG CGTGGACCTG 1800

AGCTGTAATG AGCTAAGCGA AGTCACTTTG CCAGAAAACC TGCCTCCGAA ACTACAAGAA 1860

CTAGACCTGA CTGGGAACCC CCGACTTGCC CTTGATCACA AAACCCTGGA ACTGCTGAAT 1920

AACATCCGCT GTTTCAAGAT TGATCAGCCT TCAGCAGGAG ATGGATCTGG AGCCCCAGCT 1980

GTATGGAGCC ACGGCTACAC CGAAGCTTCA GGAGTGAAAA ACAAGTTGTG TGTCGCAGCC 2040

CTGTCGGTGA ACAACTTCTG TGACAACCGG GAGGCCCTGT ACGGGGTGTT TGACGGGGAC 2100

CGGAACGTGG AGGTGCCCTA CCTTCTCCAG TGTACGATGA GTGACATTTT GGCCGAAGAG 2160

CTGCAGAAAA CCAAAAATGA AGAAGAATAC ATGGTCAATA CGTTCATTGT TATGCAAAGG 2220

AAGCTTGGAA CTGCTGGGCA GAAACTTGGA GGTGCTGCTG TCCTCTGTCA CATCAAGCAC 2280

GACCCTATGG ACCCAGGAGG GTCCTTCACC TTGACCTCTG CTAATGTGGG GAAGTGCCAG 2340

ACGGTTCTCT GTCGGAACGG GAAGCCGTTG CCTCTGTCCA GATCATATGT CATGAGCTGC 2400

GAAGAAGAAC TGAAGAGAAT TAAGCGGCAC AAGGCCATTA TCACTGAGGA CGGCAAGGTG 2460

AACGGAGTGA CGGAGTCCAC GCGCATCCTG GGGTACACCT TCCTGCACCC CAGCGTGGTG 2520

CCGCGCCCTC ACGTGCAGTC CGTGCCCCTG ACCCCCCAGG ACGAGTTCTT CATCCTGGGC 2580

AGTAAGGGCC TGTGGGACAG CCTGTCCGCC GAGGAGGCGG TGGCGGCCGT GCGCAACGTG 2640

CCCGACGCCC TGGCGGCCGC CAAGAAGCTG TGCACCCTGG CGCAGAGCTA CGGCTGCCGC 2700

GACAGCCTCA GCGCCGTGGT GGTGCAGCTG AGCGTCGCCG AGGACGGCTT CTGCTGCTGC 2760

GAGCTGGGCG CCGGCGGGGC CGGGCCCCCG CCCAGCCCCG GCATCTTCCC GCCGGCCGCG 2820

AGCATGGCGA CCAGGGACCG GCCGGCCGAC GCGCTGGGCG TGCCGTCGTC CAGCAGCGGC 2880

ATGGCCTCCG AGATGAGCAG CGAGCTGTCC ACCTCCGAGA TGAGCAGCGA GGTGGGCTCC 2940

ACGGCCTCGG ACGAGCCGCC GCCCGGCGCC CCGGCCGAGA GCAGCCCCGC CTACGCCAGC 3000

GAGCCGCGCT GCGCACTGCA CCCGGTGGGC CTGGCCCACG CGTTCCAGCG CCAGCTGTCC 3060

AGCGCCACCT TCTCCAGCGC CTTCTCCGAC AACGGCCTGG ACAGCGACGA CGAGGAGCCC 3120

ATCGAGGGCG TGTTCACCAA CGGCAGCCGC GTGGAGGTGG AGGTGGACAT CCACTGCGGC 3180

CGGGCGCGGG AGAAGGAGAG GCGGCGCCCG 3210

Domain Profile

S: 2     lvgvvsvngrrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheil  61

         ++g+++ +g +n+++ a+ s++nf++++e+     ++gv+DG+++ ev + +++++++il

Q: 663   SHGYTEASGVKNKLCVAALSVNNFCDNREA-----LYGVFDGDRNVEVPYLLQCTMSDIL  717

         689***********************9885.....9************************

S: 62    aeelesseseerkvkkalakaFlstdeelkvleeksldidksGstavvalikds......  115

         aeel+    ++++ ++++ ++F+ ++++l       ++ +k G +av+++ik++

Q: 718   AEELQ----KTKNEEEYMVNTFIVMQRKL------GTAGQKLGGAAVLCHIKHDpmdpgg  767

         ***99....999*****************......99****************999****

S: 116   ..klyvanvGdSravLcrngkavelssdHkpsredEleRieeaggsvilkdgaRvlGvLa  173

           +l+ anvG++++vLcrngk+++ls+ + +s+e+El+Ri+++++ ++++   +v+Gv++

Q: 768   sfTLTSANVGKCQTVLCRNGKPLPLSRSYVMSCEEELKRIKRHKAIITEDG--KVNGVTE  825

         *99*****************************************9999998..*******

S: 174   vsRalGdlylkpyvtpePevtshrltsedefliLasDGlwdvvsneeavslvrdvlekke  233

          +R lG ++l+p v+p+P+v+s++lt++def+iL+s+Glwd +s eeav++vr+v +

Q: 826   STRILGYTFLHPSVVPRPHVQSVPLTPQDEFFILGSKGLWDSLSAEEAVAAVRNVPD---  882

         *********************************************************...

S: 234   aeqeaakkLvklalargskdnvsaivv  260

          + +aakkL++la+++g++d++sa+vv

Q: 883   -ALAAAKKLCTLAQSYGCRDSLSAVVV  908

         .************************97

Domain Sequence
(FASTA)

SHGYTEASGV KNKLCVAALS VNNFCDNREA LYGVFDGDRN VEVPYLLQCT MSDILAEELQ 60

KTKNEEEYMV NTFIVMQRKL GTAGQKLGGA AVLCHIKHDP MDPGGSFTLT SANVGKCQTV 120

LCRNGKPLPL SRSYVMSCEE ELKRIKRHKA IITEDGKVNG VTESTRILGY TFLHPSVVPR 180

PHVQSVPLTP QDEFFILGSK GLWDSLSAEE AVAAVRNVPD ALAAAKKLCT LAQSYGCRDS 240

LSAVVV 246

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Loxodonta africana"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Schizosaccharomyces pombe"; ?>