EKS-FEC-00391

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-FEC-00391

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/IRAK	374.3	4.0E-112	189	454	266

Status

Unreviewed

Ensembl Protein

ENSFCAP00000018714

Gene Name

IRAK4

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSFCAG00000021974	ENSFCAP00000018714	ENSFCAT00000028213

Organism

Felis catus

Protein Length

460

Protein Sequence
(FASTA)

MNKPITSSTY VRSLNVGLIR KLSDFIDPQE GWKKLAVAIK KPSGDDRYNQ FHIRRFEALL 60

QTGKSPTCEL LFDWGTTNCT VGDLVDLLVQ NEFFAPASLL LPDAVPQTVN TLPAKEAVTI 120

PQKELPLCGK DRTFVLPVQD LEQNYMPPDS SSPENTSLAG SDTRFHSFSF YELKNVTNNF 180

DERPISVGGN KMGEGGFGVV YKGCVNNKTV AVKKLAAMVD ISTEELKQQF DQEIKVMAKC 240

QHENLVELLG FSSDGDDLCL VYVYMPNGSL LDRLSCLDDT PPLSWHMRCK IAQGAATGIS 300

FLHENHHIHR DIKSANILLD EDFTAKISDF GLARASEKFA QTVMTSRIVG TTAYMAPEAL 360

RGEITAKSDI YSFGVVLLEI ITGLPAVDEY REPQLLLDIK EEIEDEEKTI EDYIDTKMKD 420

SDPISIETMY SVASQCLHEK KNKRPDIKKV QQLLQDMTVS 460

Nucleotide Sequence
(FASTA)

ATGAATAAAC CCATAACATC TTCAACATAT GTGCGCTCCC TCAATGTTGG ACTAATCAGG 60

AAGCTGTCAG ATTTTATTGA TCCTCAAGAA GGATGGAAGA AGTTAGCGGT AGCTATTAAA 120

AAACCATCTG GTGATGATAG ATACAATCAG TTTCACATAA GGAGATTTGA AGCATTACTT 180

CAAACTGGAA AAAGCCCCAC TTGTGAATTA CTGTTTGACT GGGGTACCAC AAATTGCACA 240

GTTGGTGATC TTGTGGATCT TTTGGTCCAA AATGAGTTTT TTGCCCCAGC AAGTCTTTTG 300

CTACCAGATG CTGTTCCCCA AACTGTTAAT ACACTACCTG CTAAAGAAGC TGTAACAATT 360

CCGCAGAAAG AATTGCCTCT CTGTGGCAAA GACAGGACAT TTGTGTTACC TGTGCAGGAT 420

CTTGAACAAA ACTATATGCC CCCTGACTCC TCAAGTCCAG AAAATACAAG TTTAGCAGGG 480

AGTGATACAC GTTTTCACAG CTTTTCATTT TATGAATTGA AGAATGTCAC AAATAACTTT 540

GATGAAAGGC CCATTTCTGT CGGTGGCAAC AAGATGGGAG AGGGCGGGTT TGGAGTTGTG 600

TATAAAGGCT GCGTGAACAA CAAAACTGTA GCAGTGAAGA AGCTTGCAGC AATGGTTGAC 660

ATTAGTACTG AAGAACTGAA ACAGCAGTTT GATCAAGAAA TAAAAGTTAT GGCAAAGTGT 720

CAACATGAAA ACTTAGTAGA ACTACTTGGT TTCTCAAGTG ATGGAGATGA CCTCTGCTTA 780

GTGTATGTTT ACATGCCCAA TGGGTCATTG CTGGACAGGC TGTCCTGCTT GGATGATACT 840

CCACCACTTT CATGGCATAT GAGATGCAAG ATTGCTCAGG GTGCAGCTAC TGGCATCAGT 900

TTTTTACATG AAAACCATCA TATTCATAGA GACATTAAAA GTGCAAATAT CTTACTAGAT 960

GAAGACTTTA CAGCCAAAAT ATCAGACTTT GGGCTTGCAC GGGCTTCTGA GAAGTTTGCC 1020

CAAACAGTCA TGACTAGCAG AATTGTGGGA ACAACAGCTT ATATGGCACC TGAGGCTTTA 1080

CGAGGAGAAA TAACAGCCAA ATCTGACATA TACAGCTTTG GTGTGGTTTT ATTAGAAATA 1140

ATAACTGGAC TTCCAGCTGT AGATGAATAC CGTGAACCTC AGTTATTGCT AGATATTAAA 1200

GAAGAAATCG AAGATGAAGA AAAGACAATT GAAGATTATA TTGATACGAA GATGAAAGAC 1260

AGTGATCCCA TTTCCATTGA AACCATGTAT TCTGTTGCCA GTCAATGCTT GCATGAAAAG 1320

AAAAATAAGA GACCAGATAT TAAGAAGGTT CAACAGCTGC TGCAAGACAT GACAGTTTCT 1380

TGA 1383

Domain Profile

S: 4     dnrigeGgfgevyrgelkntavavkklkeeadlslkelkqsfltElkvlarfrHdnilel  63

         +n++geGgfg+vy+g+++n++vavkkl++++d+s++elkq+f++E+kv+a+++H+n++el

Q: 189   GNKMGEGGFGVVYKGCVNNKTVAVKKLAAMVDISTEELKQQFDQEIKVMAKCQHENLVEL  248

         79**********************************************************

S: 64    lgysaeseklcLvYqymknGsLedrLqcqkgsepLsWpqRlsillGtaraiefLHeasps  123

         lg+s+++++lcLvY ym+nGsL drL+c ++++pLsW++R++i++G+a +i+fLHe+  +

Q: 249   LGFSSDGDDLCLVYVYMPNGSLLDRLSCLDDTPPLSWHMRCKIAQGAATGISFLHEN--H  306

         *********************************************************..*

S: 124   lihgdiksaNiLLDekltpKlgDfglarfapesekqsstvlrtskvrgtlaYlpeefirv  183

         +ih+diksaNiLLDe++t+K++Dfglar   +sek ++tv+ ts+++gt+aY+++e++r

Q: 307   HIHRDIKSANILLDEDFTAKISDFGLAR---ASEKFAQTVM-TSRIVGTTAYMAPEALR-  361

         ****************************...9********9.*****************.

S: 184   gqltvkvDvySfGiVllEvltGlravdedrktkyLkdllkeeieeekveilekfldkkag  243

         g++t k+D+ySfG+VllE++tGl+avde r+++ L+d+ keeie+e+ +++e+++d k+

Q: 362   GEITAKSDIYSFGVVLLEIITGLPAVDEYREPQLLLDI-KEEIEDEE-KTIEDYIDTKMK  419

         *************************************9.********.9***********

S: 244   kleeellealielalaclaekakkrPtmsqvlell  278

         + ++ + e+++++a++cl+ek++krP++++v++ll

Q: 420   DSDPISIETMYSVASQCLHEKKNKRPDIKKVQQLL  454

         ********************************986

Domain Sequence
(FASTA)

GNKMGEGGFG VVYKGCVNNK TVAVKKLAAM VDISTEELKQ QFDQEIKVMA KCQHENLVEL 60

LGFSSDGDDL CLVYVYMPNG SLLDRLSCLD DTPPLSWHMR CKIAQGAATG ISFLHENHHI 120

HRDIKSANIL LDEDFTAKIS DFGLARASEK FAQTVMTSRI VGTTAYMAPE ALRGEITAKS 180

DIYSFGVVLL EIITGLPAVD EYREPQLLLD IKEEIEDEEK TIEDYIDTKM KDSDPISIET 240

MYSVASQCLH EKKNKRPDIK KVQQLL 266

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Dasypus novemcinctus"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>