EKS-HOS-00148

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-HOS-00148

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Atypical/RIO	331.8	1.1E-98	236	464	229

Status

Reviewed

Ensembl Protein

ENSP00000463660

UniProt Accession

O14730; Q8IXN9;

Protein Name

Serine/threonine-protein kinase RIO3

Protein Synonyms/Alias

RIO kinase 3; sudD homolog;

Gene Name

RIOK3

Gene Synonyms/Alias

RIOK3; SUDD;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSG00000101782	ENSP00000341874	ENST00000339486
ENSG00000101782	ENSP00000463644	ENST00000577250
ENSG00000101782	ENSP00000463791	ENST00000584130
ENSG00000101782	ENSP00000462548	ENST00000577501
ENSG00000101782	ENSP00000463660	ENST00000581585

Organism

Homo sapiens

Functional Description

Protein Length

503

Protein Sequence
(FASTA)

MDLVGVASPE PGTAAAWGPS KCPWAIPQNT ISCSLADVMS EQLAKELQLE EEAAVFPEVA 60

DLMLAQMLQM EYDREYDAQL RREEKKFNGD SKVSISFENY RKVHPYEDSD SSEDEVDWQD 120

TRDDPYRPAK PVPTPKKGFI GKGKDITTKH DEVVCGRKNT ARMENFAPEF QVGDGIGMDL 180

KLSNHVFNAL KQHAYSEERR SARLHEKKEH STAEKAVDPK TRLLMYKMVN SGMLETITGC 240

ISTGKESVVF HAYGGSMEDE KEDSKVIPTE CAIKVFKTTL NEFKNRDKYI KDDFRFKDRF 300

SKLNPRKIIR MWAEKEMHNL ARMQRAGIPC PTVVLLKKHI LVMSFIGHDQ VPAPKLKEVK 360

LNSEEMKEAY YQTLHLMRQL YHECTLVHAD LSEYNMLWHA GKVWLIDVSQ SVEPTHPHGL 420

EFLFRDCRNV SQFFQKGGVK EALSERELFN AVSGLNITAD NEADFLAEIE ALEKMNEDHV 480

QKNGRKAASF LKDDGDPPLL YDE 503

Nucleotide Sequence
(FASTA)

ATGGATCTGG TAGGAGTGGC ATCGCCTGAG CCCGGGACGG CAGCGGCCTG GGGACCCAGC 60

AAGTGTCCAT GGGCTATTCC TCAAAATACA ATATCTTGTT CTTTGGCTGA TGTAATGAGT 120

GAACAGCTGG CCAAAGAATT GCAGTTAGAA GAAGAAGCTG CCGTTTTTCC TGAAGTTGCT 180

GACCTTATGC TGGCTCAGAT GCTACAGATG GAATATGACA GAGAATATGA TGCACAGCTT 240

AGGCGTGAAG AAAAAAAATT CAATGGAGAT AGCAAAGTTT CCATTTCCTT TGAAAATTAT 300

CGAAAAGTGC ATCCTTATGA AGACAGCGAT AGCTCTGAAG ATGAGGTTGA CTGGCAGGAT 360

ACTCGTGATG ATCCCTACAG ACCAGCAAAA CCGGTTCCCA CTCCTAAAAA GGGCTTTATT 420

GGAAAAGGAA AAGATATCAC CACCAAACAT GATGAAGTAG TATGTGGGAG AAAGAACACA 480

GCAAGAATGG AAAATTTTGC ACCTGAGTTT CAGGTAGGAG ATGGAATTGG AATGGATTTA 540

AAACTATCAA ACCATGTTTT CAATGCTTTA AAACAACATG CCTACTCAGA AGAACGTCGA 600

AGTGCCCGCC TACATGAGAA AAAGGAGCAT TCTACAGCAG AAAAAGCAGT TGATCCTAAG 660

ACACGTTTAC TTATGTATAA AATGGTCAAC TCTGGAATGT TGGAGACAAT CACTGGCTGT 720

ATTAGTACAG GAAAGGAGTC TGTTGTCTTT CATGCATATG GAGGGAGCAT GGAGGATGAA 780

AAGGAAGATA GTAAAGTTAT ACCTACAGAA TGTGCCATCA AGGTATTTAA AACAACCCTT 840

AATGAATTTA AGAATCGTGA CAAATATATT AAAGATGATT TCAGGTTTAA AGATCGCTTC 900

AGTAAACTAA ATCCACGTAA GATCATCCGC ATGTGGGCAG AAAAAGAAAT GCACAATCTC 960

GCAAGAATGC AGAGAGCTGG AATTCCTTGT CCAACAGTTG TACTACTGAA GAAACACATT 1020

TTAGTTATGT CTTTTATTGG CCATGATCAA GTTCCAGCCC CTAAATTAAA AGAAGTAAAG 1080

CTCAATAGTG AAGAAATGAA AGAAGCCTAC TATCAAACTC TTCATTTGAT GCGGCAGTTA 1140

TATCATGAAT GTACGCTTGT CCATGCTGAC CTCAGTGAGT ATAACATGCT GTGGCATGCT 1200

GGAAAGGTCT GGTTGATCGA TGTCAGTCAG TCAGTAGAAC CTACCCACCC TCACGGCCTG 1260

GAGTTCTTGT TCCGGGACTG CAGGAATGTC TCGCAGTTTT TCCAGAAAGG AGGAGTCAAG 1320

GAAGCCCTTA GTGAACGAGA ACTCTTCAAT GCTGTTTCAG GCTTAAACAT CACAGCAGAT 1380

AATGAAGCTG ATTTTTTAGC TGAGATAGAA GCTTTGGAGA AAATGAATGA AGATCACGTT 1440

CAGAAGAATG GAAGGAAAGC TGCTTCATTT TTGAAAGATG ATGGAGACCC ACCACTACTA 1500

TATGATGAAT AG 1512

Domain Profile

S: 2     svgntigvgkesdvykvsekngee...........raiKiyktsllvlknrdkYvdgefr  50

         +++++i++gkes v++++  ++e+           +aiK++kt+l+++knrdkY++++fr

Q: 236   TITGCISTGKESVVFHAYGGSMEDekedskvipteCAIKVFKTTLNEFKNRDKYIKDDFR  295

         79*********************999**********************************

S: 51    fkksrskanprklsrlwAeKEfrnlkrlyekgvpvPepidlkrhvlvmeligrdgypapk  110

         fk+++sk nprk++r+wAeKE++nl+r++++g+p+P+++ lk+h+lvm++ig+d++papk

Q: 296   FKDRFSKLNPRKIIRMWAEKEMHNLARMQRAGIPCPTVVLLKKHILVMSFIGHDQVPAPK  355

         ************************************************************

S: 111   lkdvklkeeeikelYsdllalivklynegrLvHaDlsEfnilleddklvliDvsqsveie  170

         lk+vkl++ee+ke+Y+++l+l+++ly+e++LvHaDlsE+n+l++++k++liDvsqsve++

Q: 356   LKEVKLNSEEMKEAYYQTLHLMRQLYHECTLVHADLSEYNMLWHAGKVWLIDVSQSVEPT  415

         ************************************************************

S: 171   HpdaleflrrDvknvkefFkkklvydvlrerelfelvsasgltkekead  219

         Hp++lefl rD++nv++fF+k +v+++l+erelf++vs+ ++t+++ead

Q: 416   HPHGLEFLFRDCRNVSQFFQKGGVKEALSERELFNAVSGLNITADNEAD  464

         **********************************************996

Domain Sequence
(FASTA)

TITGCISTGK ESVVFHAYGG SMEDEKEDSK VIPTECAIKV FKTTLNEFKN RDKYIKDDFR 60

FKDRFSKLNP RKIIRMWAEK EMHNLARMQR AGIPCPTVVL LKKHILVMSF IGHDQVPAPK 120

LKEVKLNSEE MKEAYYQTLH LMRQLYHECT LVHADLSEYN MLWHAGKVWL IDVSQSVEPT 180

HPHGLEFLFR DCRNVSQFFQ KGGVKEALSE RELFNAVSGL NITADNEAD 229

Keyword

Alternative splicing; ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Phosphoprotein; Polymorphism; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macropus eugenii"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>