EPS-HOS-00034

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-HOS-00034

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	65.5	3.1E-17	136	316	181

Status

Reviewed

Ensembl Protein

ENSP00000228705

UniProt Accession

Q9ULR3; B1Q2A9; B2RXG4; Q6PI86;

Protein Name

Protein phosphatase 1H

Protein Synonyms/Alias

Gene Name

PPM1H

Gene Synonyms/Alias

PPM1H; ARHCL1, KIAA1157, URCC2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSG00000111110	ENSP00000228705	ENST00000228705

Organism

Homo sapiens

Functional Description

Protein Length

514

Protein Sequence
(FASTA)

MLTRVKSAVA NFMGGIMAGS SGSEHGGGSC GGSDLPLRFP YGRPEFLGLS QDEVECSADH 60

IARPILILKE TRRLPWATGY AEVINAGKST HNEDQASCEV LTVKKKAGAV TSTPNRNSSK 120

RRSSLPNGEG LQLKENSESE GVSCHYWSLF DGHAGSGAAV VASRLLQHHI TEQLQDIVDI 180

LKNSAVLPPT CLGEEPENTP ANSRTLTRAA SLRGGVGAPG SPSTPPTRFF TEKKIPHECL 240

VIGALESAFK EMDLQIERER SSYNISGGCT ALIVICLLGK LYVANAGDSR AIIIRNGEII 300

PMSSEFTPET ERQRLQYLAF MQPHLLGNEF THLEFPRRVQ RKELGKKMLY RDFNMTGWAY 360

KTIEDEDLKF PLIYGEGKKA RVMATIGVTR GLGDHDLKVH DSNIYIKPFL SSAPEVRIYD 420

LSKYDHGSDD VLILATDGLW DVLSNEEVAE AITQFLPNCD PDDPHRYTLA AQDLVMRARG 480

VLKDRGWRIS NDRLGSGDDI SVYVIPLIHG NKLS 514

Nucleotide Sequence
(FASTA)

ATGCTCACTC GAGTGAAATC TGCCGTGGCC AATTTCATGG GCGGCATCAT GGCTGGCAGC 60

TCAGGCTCCG AGCACGGCGG CGGCAGCTGC GGAGGCTCGG ACCTGCCCCT GCGTTTCCCC 120

TACGGGCGGC CAGAGTTCCT GGGGCTGTCT CAGGACGAGG TGGAGTGCAG CGCCGACCAC 180

ATCGCCCGCC CCATCCTCAT CCTCAAGGAG ACTCGGCGGC TGCCCTGGGC CACTGGCTAC 240

GCAGAGGTTA TCAATGCCGG GAAGAGCACA CACAATGAAG ACCAAGCCAG CTGTGAGGTG 300

CTCACTGTGA AGAAGAAGGC AGGGGCCGTG ACCTCAACCC CAAACAGGAA CTCATCCAAG 360

AGACGGTCCT CCCTTCCCAA TGGGGAAGGG CTGCAGCTGA AGGAGAACTC GGAATCCGAG 420

GGTGTTTCCT GCCACTATTG GTCGCTGTTT GACGGGCACG CGGGGTCCGG GGCCGCGGTG 480

GTGGCGTCAC GCCTGCTGCA GCACCACATC ACGGAGCAGC TGCAGGACAT CGTGGACATC 540

CTGAAGAACT CCGCCGTCCT GCCCCCTACC TGCCTGGGGG AGGAGCCTGA GAACACGCCC 600

GCCAACAGCC GGACTCTGAC CCGGGCAGCC TCCCTGCGCG GAGGGGTGGG GGCCCCGGGC 660

TCCCCCAGCA CGCCCCCCAC ACGCTTCTTT ACCGAGAAGA AGATTCCCCA TGAGTGCCTG 720

GTCATCGGAG CGCTTGAAAG TGCATTCAAG GAAATGGACC TACAGATAGA ACGAGAGAGG 780

AGTTCATATA ATATATCTGG TGGCTGCACG GCCCTCATTG TGATTTGCCT TTTGGGGAAG 840

CTGTATGTTG CAAATGCTGG GGATAGCAGG GCCATAATCA TCAGAAATGG AGAAATTATC 900

CCCATGTCTT CAGAATTTAC CCCCGAGACG GAGCGCCAGC GACTTCAGTA CCTGGCATTC 960

ATGCAGCCTC ACTTGCTGGG AAATGAGTTC ACACATTTGG AGTTTCCAAG GAGAGTACAG 1020

AGAAAGGAGC TTGGAAAGAA GATGCTCTAC AGGGACTTTA ATATGACAGG CTGGGCATAC 1080

AAAACCATTG AGGATGAGGA CTTGAAGTTC CCCCTTATAT ATGGAGAAGG CAAGAAGGCC 1140

CGGGTAATGG CAACTATTGG AGTGACCAGG GGACTTGGGG ACCATGACCT GAAGGTGCAT 1200

GACTCCAACA TCTACATTAA ACCATTCCTG TCTTCAGCTC CAGAGGTAAG AATCTACGAT 1260

CTTTCAAAAT ATGATCATGG ATCAGATGAT GTGCTGATCT TGGCCACTGA TGGACTCTGG 1320

GACGTTTTAT CAAATGAAGA AGTAGCAGAA GCAATCACTC AGTTTCTTCC TAACTGTGAT 1380

CCAGATGATC CTCACAGGTA CACACTGGCA GCTCAGGACC TGGTGATGCG TGCCCGGGGT 1440

GTGCTGAAGG ACAGAGGATG GCGGATATCT AATGACCGAC TGGGCTCAGG AGACGACATT 1500

TCTGTATATG TCATTCCTTT AATACATGGA AACAAGCTGT CATGA 1545

Domain Profile

S: 32    kdr.....laffgvyDGhggsevakfcseklheilaeele....................  66

         +++      ++   +DGh+gs +a  +s  l+ +++e+l+

Q: 136   NSEsegvsCHYWSLFDGHAGSGAAVVASRLLQHHITEQLQdivdilknsavlpptclgee  195

         222467779***************************************************

S: 67    .....................................sseseerkvkkalakaFlstdee  89

                                              ++ ++e  v  al++aF+++d +

Q: 196   pentpansrtltraaslrggvgapgspstpptrffteKKIPHECLVIGALESAFKEMDLQ  255

         ******99999999999999999999999999998777777788888*************

S: 90    lkvleeksldidk.sGstavvalikdsklyvanvGdSravLcrngkavelssdHkpsred  148

         +   e+++++ +   G+ta++++    klyvan+GdSra++ rng+++++ss+++p+

Q: 256   I---ERERSSYNIsGGCTALIVICLLGKLYVANAGDSRAIIIRNGEIIPMSSEFTPET--  310

         *...44433444436777777777777*****************************98..

S: 149   EleRie  154

         E++R++

Q: 311   ERQRLQ  316

Domain Sequence
(FASTA)

NSESEGVSCH YWSLFDGHAG SGAAVVASRL LQHHITEQLQ DIVDILKNSA VLPPTCLGEE 60

PENTPANSRT LTRAASLRGG VGAPGSPSTP PTRFFTEKKI PHECLVIGAL ESAFKEMDLQ 120

IERERSSYNI SGGCTALIVI CLLGKLYVAN AGDSRAIIIR NGEIIPMSSE FTPETERQRL 180

Q 181

Keyword

Complete proteome; Hydrolase; Phosphoprotein; Protein phosphatase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>