| Tag | Content |
|---|
| EKPD ID | EPS-HOS-00135 |
| Classification | | Group/Family | Score | E-Value | Start | End | Domain Length |
|---|
| PPP/PP2B | 418.8 | 1.6E-125 | 80 | 280 | 201 |
|
| Status | Reviewed |
| Ensembl Protein | ENSP00000429379 |
| UniProt Accession | P48454; Q9BSS6; Q9H4M5; |
| Protein Name | Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform |
| Protein Synonyms/Alias | CAM-PRP catalytic subunit; Calcineurin, testis-specific catalytic subunit; Calmodulin-dependent calcineurin A subunit gamma isoform; |
| Gene Name | PPP3CC |
| Gene Synonyms/Alias | PPP3CC; CALNA3, CNA3; |
| Ensembl Information | |
| Organism | Homo sapiens |
| Functional Description | Calcium-dependent, calmodulin-stimulated proteinphosphatase. This subunit may have a role in the calmodulin activation of calcineurin. |
| Protein Length | 326 |
Protein Sequence
(FASTA) | | MSGRRFHLST TDRVIKAVPF PPTQRLTFKE VFENGKPKVD VLKNHLVKEG RLEEEVALKI 60 | | INDGAAILRQ EKTMIEVDAP ITVCGDIHGQ FFDLMKLFEV GGSPSNTRYL FLGDYVDRGY 120 | | FSIECVLYLW SLKINHPKTL FLLRGNHECR HLTDYFTFKQ ECRIKYSEQV YDACMETFDC 180 | | LPLAALLNQQ FLCVHGGMSP EITSLDDIRK LDRFTEPPAF GPVCDLLWSD PSEDYGNEKT 240 | | LEHYTHNTVR GCSYFYSYPA VCEFLQNNNL LSIIRAHEAQ DAGYRMYRKS QATGFPSLIT 300 | | IFSAPNYLDV YNNKGKGIQQ YLSLNL 326 |
|
Nucleotide Sequence
(FASTA) | | ATGTCCGGGA GGCGCTTCCA CCTCTCCACC ACCGACCGCG TCATCAAAGC TGTCCCCTTT 60 | | CCTCCAACCC AACGGCTTAC TTTCAAGGAA GTATTTGAGA ATGGGAAACC TAAAGTTGAT 120 | | GTTTTAAAAA ACCATTTGGT AAAGGAAGGA CGACTGGAAG AGGAAGTAGC CTTAAAGATA 180 | | ATCAATGATG GGGCTGCCAT CCTGAGGCAA GAGAAGACTA TGATAGAAGT AGATGCTCCA 240 | | ATCACAGTAT GTGGTGATAT TCATGGACAA TTCTTTGACC TAATGAAGTT ATTTGAAGTT 300 | | GGAGGATCAC CTAGTAACAC ACGCTACCTC TTTCTGGGTG ACTATGTGGA CAGAGGCTAT 360 | | TTCAGTATAG AGTGTGTGCT GTATTTATGG AGTTTAAAGA TTAATCATCC CAAAACATTG 420 | | TTTCTGCTTC GGGGAAATCA TGAATGCAGG CATCTTACAG ACTATTTCAC CTTCAAACAG 480 | | GAATGTCGAA TCAAATATTC GGAACAGGTG TATGATGCCT GTATGGAGAC ATTTGACTGT 540 | | CTTCCTCTTG CTGCCCTCTT AAACCAGCAG TTTCTCTGTG TACATGGAGG AATGTCACCT 600 | | GAAATTACTT CTTTAGATGA CATTAGGAAA TTAGACAGGT TTACGGAACC TCCCGCCTTT 660 | | GGACCTGTGT GTGACCTGCT TTGGTCTGAT CCCTCAGAGG ATTATGGCAA TGAGAAGACC 720 | | TTGGAGCACT ATACCCACAA CACTGTCCGA GGGTGCTCTT ATTTCTACAG TTACCCTGCA 780 | | GTTTGTGAAT TTTTGCAGAA CAATAATTTA CTATCAATTA TCAGAGCCCA TGAAGCCCAA 840 | | GATGCTGGGT ATCGAATGTA CAGGAAGAGC CAAGCCACAG GCTTTCCATC ACTTATTACA 900 | | ATTTTCTCTG CCCCCAATTA CCTAGATGTC TATAACAATA AAGGTAAAGG AATCCAGCAA 960 | | TATTTGAGTT TGAATTTATG A 981 |
|
| Domain Profile | S: 1 pvtvcgdihgqffdllklfevggspantrylflgdyvdrgyfsiecvlylyalkilypkt 60 | p+tvcgdihgqffdl+klfevggsp+ntrylflgdyvdrgyfsiecvlyl++lki++pkt | Q: 80 PITVCGDIHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRGYFSIECVLYLWSLKINHPKT 139 | 9*********************************************************** |
| S: 61 lfllrgnhecrhlteyftfkqelkikyservydacleafdalplaallnqqflcvhggls 120 | lfllrgnhecrhlt+yftfkqe++ikyse+vydac+e+fd+lplaallnqqflcvhgg+s | Q: 140 LFLLRGNHECRHLTDYFTFKQECRIKYSEQVYDACMETFDCLPLAALLNQQFLCVHGGMS 199 | ************************************************************ |
| S: 121 pelktlddirkldrfkeppayglmcdllwsdpledfgnekseeefvhnsvrgcsyfysyk 180 | pe+++lddirkldrf eppa+g++cdllwsdp ed+gnek+ e+++hn+vrgcsyfysy+ | Q: 200 PEITSLDDIRKLDRFTEPPAFGPVCDLLWSDPSEDYGNEKTLEHYTHNTVRGCSYFYSYP 259 | ************************************************************ |
| S: 181 avceflqennllsiiraheaq 201 | avceflq+nnllsiiraheaq | Q: 260 AVCEFLQNNNLLSIIRAHEAQ 280 | ********************8 |
|
Domain Sequence
(FASTA) | | PITVCGDIHG QFFDLMKLFE VGGSPSNTRY LFLGDYVDRG YFSIECVLYL WSLKINHPKT 60 | | LFLLRGNHEC RHLTDYFTFK QECRIKYSEQ VYDACMETFD CLPLAALLNQ QFLCVHGGMS 120 | | PEITSLDDIR KLDRFTEPPA FGPVCDLLWS DPSEDYGNEK TLEHYTHNTV RGCSYFYSYP 180 | | AVCEFLQNNN LLSIIRAHEA Q 201 |
|
| Keyword | Alternative splicing; Calmodulin-binding; Complete proteome; Hydrolase; Iron; Metal-binding; Polymorphism; Protein phosphatase; Reference proteome; Zinc. |
| Sequence Source | Ensembl |
| Orthology | |
| Gene Ontology | |
| KEGG | |
| InterPros | |
| Pfam | |
| SMARTs | |
| Prosites | |
| Prints | |
| Created Date | 20-Feb-2013 |