EKS-HOS-00218

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-HOS-00218

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/NKF4	690.2	2.1E-207	63	392	330

Status

Reviewed

Ensembl Protein

ENSP00000426612

UniProt Accession

Q8TDR2; B2RBM3; C7ENV8; Q2NKW6; Q5T3R1; Q5T3R2; Q96AB4; Q9BZ06;

Protein Name

Serine/threonine-protein kinase 35

Protein Synonyms/Alias

CLP-36-interacting kinase 1; CLIK-1; PDLIM1-interacting kinase 1; Serine/threonine-protein kinase 35 L1;

Gene Name

STK35

Gene Synonyms/Alias

STK35; CLIK1, PDIK1, STK35L1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSG00000125834	ENSP00000246032	ENST00000246032
ENSG00000125834	ENSP00000426612	ENST00000493263
ENSG00000125834	ENSP00000370891	ENST00000381482
ENSG00000125834	ENSP00000382937	ENST00000400064

Organism

Homo sapiens

Functional Description

Protein Length

395

Protein Sequence
(FASTA)

GARRGTQSPE RKRRSPVPRA PSTKLRPAAA ARAMDPVAAE APGEAFLARR RPEGGGGSAR 60

PRYSLLAEIG RGSYGVVYEA VAGRSGARVA VKKIRCDAPE NVELALAEFW ALTSLKRRHQ 120

NVVQFEECVL QRNGLAQRMS HGNKSSQLYL RLVETSLKGE RILGYAEEPC YLWFVMEFCE 180

GGDLNQYVLS RRPDPATNKS FMLQLTSAIA FLHKNHIVHR DLKPDNILIT ERSGTPILKV 240

ADFGLSKVCA GLAPRGKEGN QDNKNVNVNK YWLSSACGSD FYMAPEVWEG HYTAKADIFA 300

LGIIIWAMIE RITFIDSETK KELLGTYIKQ GTEIVPVGEA LLENPKMELH IPQKRRTSMS 360

EGIKQLLKDM LAANPQDRPD AFELETRMDQ VTCAA 395

Nucleotide Sequence
(FASTA)

GGCGCCCGCA GAGGTACACA AAGCCCGGAG CGGAAAAGGC GAAGCCCAGT GCCGCGGGCG 60

CCCAGCACGA AGCTGAGGCC GGCGGCGGCG GCCCGGGCCA TGGATCCGGT GGCGGCCGAG 120

GCCCCGGGCG AGGCCTTCCT GGCGCGGCGA CGGCCTGAGG GCGGTGGCGG GTCCGCGCGG 180

CCGCGTTACA GCCTGTTGGC GGAGATCGGG CGCGGCAGCT ACGGCGTGGT TTATGAGGCA 240

GTGGCCGGGC GCAGCGGGGC CCGGGTGGCG GTCAAGAAGA TCCGCTGCGA CGCCCCCGAG 300

AACGTGGAGC TGGCGCTGGC TGAATTCTGG GCCCTCACCA GCCTCAAGCG GCGCCACCAG 360

AACGTCGTGC AGTTTGAGGA GTGCGTCCTG CAGCGCAATG GGTTAGCCCA GCGCATGAGT 420

CACGGCAACA AGAGCTCGCA GCTTTACCTG CGCCTGGTGG AGACCTCGCT GAAAGGAGAA 480

AGGATCCTGG GTTATGCTGA GGAGCCCTGC TATCTCTGGT TTGTCATGGA GTTCTGTGAA 540

GGTGGAGACC TGAATCAGTA TGTCCTGTCC CGGAGGCCAG ACCCAGCCAC CAACAAAAGT 600

TTCATGCTAC AGCTGACGAG CGCCATTGCC TTCCTGCACA AAAACCATAT TGTGCACAGG 660

GACCTGAAGC CAGACAACAT CCTCATCACA GAGCGGTCTG GCACCCCCAT CCTCAAAGTG 720

GCCGACTTTG GACTAAGCAA GGTCTGTGCT GGGCTGGCAC CCCGAGGCAA AGAGGGCAAT 780

CAAGACAACA AAAATGTGAA TGTGAATAAG TACTGGCTGT CCTCAGCCTG CGGTTCGGAC 840

TTCTACATGG CTCCTGAAGT CTGGGAGGGA CACTACACAG CCAAGGCGGA CATCTTTGCC 900

CTGGGCATTA TCATCTGGGC AATGATAGAA AGAATCACTT TTATTGACTC TGAGACCAAG 960

AAGGAGCTCC TGGGGACCTA CATTAAACAG GGGACTGAGA TCGTCCCTGT TGGTGAGGCG 1020

CTGCTAGAAA ACCCAAAGAT GGAGTTGCAC ATCCCCCAAA AACGCAGGAC TTCCATGTCT 1080

GAGGGGATCA AGCAGCTCTT GAAAGATATG TTAGCTGCTA ACCCACAGGA CCGGCCTGAT 1140

GCCTTTGAAC TTGAAACCAG AATGGACCAG GTCACATGTG CTGCTTAA 1188

Domain Profile

S: 1     ydllaevgrgsygvvyeavirkssarvavkkircdapenvelalaefwalsslkrrhqnv  60

         y+llae+grgsygvvyeav+++s+arvavkkircdapenvelalaefwal+slkrrhqnv

Q: 63    YSLLAEIGRGSYGVVYEAVAGRSGARVAVKKIRCDAPENVELALAEFWALTSLKRRHQNV  122

         99**********************************************************

S: 61    vqleecvlqkdglvqkmshgs.nsslylrlvetslkgeiild.aeeayylwfvmefcegg  118

         vq+eecvlq++gl+q+mshg+ +s+lylrlvetslkge+il+ aee++ylwfvmefcegg

Q: 123   VQFEECVLQRNGLAQRMSHGNkSSQLYLRLVETSLKGERILGyAEEPCYLWFVMEFCEGG  182

         *********************999************************************

S: 119   dlneyllsrkpdrktnksfmlqlssalaflhknqivhrdlkpdnilisesrldtsdlepi  178

         dln+y+lsr+pd++tnksfmlql+sa+aflhkn+ivhrdlkpdnili+e r++t    pi

Q: 183   DLNQYVLSRRPDPATNKSFMLQLTSAIAFLHKNHIVHRDLKPDNILITE-RSGT----PI  237

         *************************************************.****....**

S: 179   lkvadfglskvcaa......egqqdeknvsvnkyflssacgsdfymapevweghytakad  232

         lkvadfglskvca+      eg+qd+knv+vnky+lssacgsdfymapevweghytakad

Q: 238   LKVADFGLSKVCAGlaprgkEGNQDNKNVNVNKYWLSSACGSDFYMAPEVWEGHYTAKAD  297

         ************************************************************

S: 233   ifalgiiiwamleritfidsetkkellgsyvkqgteivpvgeallenpkmellipvkkk.  291

         ifalgiiiwam+eritfidsetkkellg+y+kqgteivpvgeallenpkmel+ip+k++

Q: 298   IFALGIIIWAMIERITFIDSETKKELLGTYIKQGTEIVPVGEALLENPKMELHIPQKRRt  357

         ***********************************************************9

S: 292   smserlkqllkemlaanpqdrpdafelelrlvqva  326

         smse++kqllk+mlaanpqdrpdafele+r++qv+

Q: 358   SMSEGIKQLLKDMLAANPQDRPDAFELETRMDQVT  392

         *********************************96

Domain Sequence
(FASTA)

YSLLAEIGRG SYGVVYEAVA GRSGARVAVK KIRCDAPENV ELALAEFWAL TSLKRRHQNV 60

VQFEECVLQR NGLAQRMSHG NKSSQLYLRL VETSLKGERI LGYAEEPCYL WFVMEFCEGG 120

DLNQYVLSRR PDPATNKSFM LQLTSAIAFL HKNHIVHRDL KPDNILITER SGTPILKVAD 180

FGLSKVCAGL APRGKEGNQD NKNVNVNKYW LSSACGSDFY MAPEVWEGHY TAKADIFALG 240

IIIWAMIERI TFIDSETKKE LLGTYIKQGT EIVPVGEALL ENPKMELHIP QKRRTSMSEG 300

IKQLLKDMLA ANPQDRPDAF ELETRMDQVT 330

Keyword

ATP-binding; Complete proteome; Cytoplasm; Kinase; Nucleotide-binding; Nucleus; Phosphoprotein; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dasypus novemcinctus"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xiphophorus maculatus"; ?>