EPS-HOS-00063

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-HOS-00063

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Asp-Based PTP/FCP	181.3	6.4E-53	217	378	162

Status

Reviewed

Ensembl Protein

ENSP00000380000

UniProt Accession

Q05D32; Q3ZTU1; Q6AI06; Q8IYI9; Q9NVT2; Q9NZX8; Q9P030;

Protein Name

CTD small phosphatase-like protein 2

Protein Synonyms/Alias

CTDSP-like 2;

Gene Name

CTDSPL2

Gene Synonyms/Alias

CTDSPL2; HSPC058, HSPC129;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSG00000137770	ENSP00000380000	ENST00000396780
ENSG00000137770	ENSP00000452837	ENST00000558966
ENSG00000137770	ENSP00000453612	ENST00000558791
ENSG00000137770	ENSP00000454187	ENST00000559793
ENSG00000137770	ENSP00000453538	ENST00000560620
ENSG00000137770	ENSP00000454154	ENST00000558968
ENSG00000137770	ENSP00000260327	ENST00000260327
ENSG00000137770	ENSP00000453051	ENST00000558373

Organism

Homo sapiens

Functional Description

Probable phosphatase (By similarity).

Protein Length

394

Protein Sequence
(FASTA)

MRLRTRKASQ QSNQIQTQRT ARAKRKYSEV DDSLPSGGEK PSKNETGLLS SIKKFIKGST 60

PKEERENPSK RSRIERDIDN NLITSTPRAG EKPNKQISRV RRKSQVNGEA GSYEMTNQHV 120

KQNGKLEDNP SSGSPPRTTL LGTIFSPVFN FFSPANKNAP VTPDSGYSSA HAEATYEEDW 180

EVFDPYYFIK HVPPLTEEQL NRKPALPLKT RSTPEFSLVL DLDETLVHCS LNELEDAALT 240

FPVLFQDVIY QVYVRLRPFF REFLERMSQM YEIILFTASK KVYADKLLNI LDPKKQLVRH 300

RLFREHCVCV QGNYIKDLNI LGRDLSKTII IDNSPQAFAY QLSNGIPIES WFMDKNDNEL 360

LKLIPFLEKL VELNEDVRPH IRDRFRLHDL LPPD 394

Nucleotide Sequence
(FASTA)

ATGAGGCTGA GAACACGGAA AGCTTCTCAG CAGTCAAATC AAATCCAAAC ACAACGCACT 60

GCCAGAGCAA AGAGGAAATA TTCAGAGGTT GATGATAGCC TGCCTTCAGG AGGAGAAAAA 120

CCATCGAAGA ATGAAACCGG CTTGTTGTCT TCAATTAAAA AATTTATTAA AGGAAGCACA 180

CCTAAGGAAG AGAGAGAAAA TCCTTCAAAA CGGAGTAGAA TTGAACGTGA TATAGATAAC 240

AATTTGATCA CGTCAACACC AAGAGCAGGA GAAAAACCTA ACAAACAGAT ATCTCGAGTA 300

AGACGGAAAA GTCAAGTAAA TGGAGAAGCT GGTAGTTATG AAATGACAAA TCAACATGTA 360

AAACAAAATG GAAAATTAGA AGATAATCCT TCCTCTGGCA GTCCTCCAAG GACTACTTTG 420

TTGGGGACCA TATTTTCACC TGTCTTCAAC TTTTTTTCAC CAGCAAATAA AAATGCACCA 480

GTAACTCCAG ATAGTGGTTA TTCATCAGCC CACGCGGAGG CCACCTATGA AGAAGACTGG 540

GAAGTATTTG ACCCCTATTA TTTCATCAAA CATGTCCCGC CACTGACAGA AGAACAACTA 600

AATAGGAAAC CTGCTCTTCC GTTGAAAACA AGAAGCACAC CGGAATTCTC CCTAGTTTTA 660

GACTTGGATG AAACACTAGT GCATTGTAGT CTAAATGAGC TAGAAGATGC AGCACTTACT 720

TTTCCAGTCC TTTTCCAAGA TGTCATTTAT CAGGTTTATG TGAGATTAAG ACCATTTTTC 780

AGGGAATTCC TGGAACGAAT GTCTCAGATG TATGAGATCA TTCTTTTTAC TGCTTCTAAG 840

AAGGTGTATG CAGACAAGTT ACTGAACATA CTAGACCCTA AAAAGCAACT GGTCAGGCAC 900

CGGCTTTTCC GTGAACATTG TGTTTGTGTA CAAGGAAACT ATATAAAGGA CTTAAATATT 960

CTTGGAAGAG ATCTTTCAAA AACTATAATA ATTGACAACT CACCACAAGC CTTTGCATAT 1020

CAGCTTTCTA ATGGAATCCC TATAGAAAGT TGGTTTATGG ATAAAAATGA CAATGAACTC 1080

CTAAAATTGA TTCCATTCCT GGAGAAGCTT GTAGAACTGA ATGAAGATGT TCGACCACAC 1140

ATCAGAGACA GATTTCGCTT GCATGATTTG CTGCCCCCAG ATTAA 1185

Domain Profile

S: 2     tLVLDLDetLvhsksekdee.........e.ektkasvkkRPgldeFLkelskayevvif  51

          LVLDLDetLvh++ ++ e+         +   ++++v +RP+ +eFL+++s++ye+++f

Q: 217   SLVLDLDETLVHCSLNELEDaaltfpvlfQdVIYQVYVRLRPFFREFLERMSQMYEIILF  276

         59************544443467777765258899*************************

S: 52    tasskeyadavldkldpkkklfkkrlyresctlengkyvKdLsllgrdlskvvivDdspr  111

         tas+k yad++l++ldpkk+l+++rl+re+c++ +g+y+KdL++lgrdlsk++i+D+sp+

Q: 277   TASKKVYADKLLNILDPKKQLVRHRLFREHCVCVQGNYIKDLNILGRDLSKTIIIDNSPQ  336

         ************************************************************

S: 112   sfelqpdnlipiepfygdsdkdtellkllpflealeks.ddvr  153

         +f+ q +n+ipie++++d ++d+ellkl+pfle+l +  +dvr

Q: 337   AFAYQLSNGIPIESWFMD-KNDNELLKLIPFLEKLVELnEDVR  378

         ******************.999**********66665559997

Domain Sequence
(FASTA)

SLVLDLDETL VHCSLNELED AALTFPVLFQ DVIYQVYVRL RPFFREFLER MSQMYEIILF 60

TASKKVYADK LLNILDPKKQ LVRHRLFREH CVCVQGNYIK DLNILGRDLS KTIIIDNSPQ 120

AFAYQLSNGI PIESWFMDKN DNELLKLIPF LEKLVELNED VR 162

Keyword

Acetylation; Alternative splicing; Complete proteome; Hydrolase; Phosphoprotein; Polymorphism; Protein phosphatase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>