| Tag | Content |
|---|
| EKPD ID | EKS-HOS-00072 |
| Classification | | Group/Family | Score | E-Value | Start | End | Domain Length |
|---|
| CMGC/CDK | 351.3 | 1.9E-104 | 52 | 336 | 285 |
|
| Status | Reviewed |
| Ensembl Protein | ENSP00000260967 |
| UniProt Accession | Q96Q40; A8K8R9; B8ZZX0; C9J1N8; C9K003; Q4ZG86; Q53TV1; Q6ZMR9; Q8IUP1; |
| Protein Name | Cyclin-dependent kinase 15 |
| Protein Synonyms/Alias | Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 7 protein; Cell division protein kinase 15; Serine/threonine-protein kinase ALS2CR7; Serine/threonine-protein kinase PFTAIRE-2; |
| Gene Name | CDK15 |
| Gene Synonyms/Alias | CDK15; ALS2CR7, PFTK2; |
| Ensembl Information | |
| Organism | Homo sapiens |
| Functional Description | Serine/threonine-protein kinase involved in the controlof the eukaryotic cell cycle, whose activity is controlled by an associated cyclin (By similarity). |
| Protein Length | 384 |
Protein Sequence
(FASTA) | | MTSFHPRGLQ AARAQKFKSK RPRSNSDCFQ EEDLRQGFQW RKSLPFGAAS SYLNLEKLGE 60 | | GSYATVYKGI SRINGQLVAL KVISMNAEEG VPFTAIREAS LLKGLKHANI VLLHDIIHTK 120 | | ETLTFVFEYM HTDLAQYMSQ HPGGLHPHNV RLFMFQLLRG LAYIHHQHVL HRDLKPQNLL 180 | | ISHLGELKLA DFGLARAKSI PSQTYSSEVV TLWYRPPDAL LGATEYSSEL DIWGAGCIFI 240 | | EMFQGQPLFP GVSNILEQLE KIWEVLGVPT EDTWPGVSKL PNYNPEWFPL PTPRSLHVVW 300 | | NRLGRVPEAE DLASQMLKGF PRDRVSAQEA LVHDYFSALP SQLYQLPDEE SLFTVSGVRL 360 | | KPEMCDLLAS YQKGHHPAQF SKCW 384 |
|
Nucleotide Sequence
(FASTA) | | ATGACTTCAT TTCACCCCAG GGGACTTCAA GCTGCCCGTG CCCAGAAGTT CAAGAGTAAA 60 | | AGGCCACGGA GTAACAGTGA TTGTTTTCAG GAAGAGGATC TGAGGCAGGG TTTTCAGTGG 120 | | AGGAAGAGCC TCCCTTTTGG GGCAGCCTCA TCTTACTTGA ACTTGGAGAA GCTGGGTGAA 180 | | GGCTCTTATG CGACAGTTTA CAAGGGGATT AGCAGAATAA ATGGACAACT AGTGGCTTTA 240 | | AAAGTCATCA GCATGAATGC AGAGGAAGGA GTCCCATTTA CAGCTATCCG AGAAGCTTCT 300 | | CTCCTGAAGG GTTTGAAACA TGCCAATATT GTGCTCCTGC ATGACATAAT CCACACCAAA 360 | | GAGACACTGA CATTCGTTTT TGAATACATG CACACAGACC TGGCCCAGTA TATGTCTCAG 420 | | CATCCAGGAG GGCTTCATCC TCATAATGTC AGACTTTTCA TGTTTCAACT TTTGCGGGGC 480 | | CTGGCGTACA TCCACCACCA ACACGTTCTT CACAGGGACC TGAAACCTCA GAACTTACTC 540 | | ATCAGTCACC TGGGAGAGCT CAAACTGGCT GATTTTGGTC TTGCCCGGGC CAAGTCCATT 600 | | CCCAGCCAGA CATACTCTTC AGAAGTCGTG ACCCTCTGGT ACCGGCCCCC TGATGCTTTG 660 | | CTGGGAGCCA CTGAATATTC CTCTGAGCTG GACATATGGG GTGCAGGCTG CATCTTTATT 720 | | GAAATGTTCC AGGGTCAACC TTTGTTTCCT GGGGTTTCCA ACATCCTTGA ACAGCTGGAG 780 | | AAAATCTGGG AGGTGCTGGG AGTCCCTACA GAGGATACTT GGCCGGGAGT CTCCAAGCTA 840 | | CCTAACTACA ATCCAGAATG GTTCCCACTG CCTACGCCTC GAAGCCTTCA TGTTGTCTGG 900 | | AACAGGCTGG GCAGGGTTCC TGAAGCTGAA GACCTGGCCT CCCAGATGCT AAAAGGCTTT 960 | | CCCAGAGACC GCGTCTCCGC CCAGGAAGCA CTTGTTCATG ATTATTTCAG CGCCCTGCCA 1020 | | TCTCAGCTGT ACCAGCTTCC TGATGAGGAG TCTTTGTTTA CAGTTTCAGG AGTGAGGCTA 1080 | | AAGCCAGAAA TGTGTGACCT TTTGGCCTCC TACCAGAAAG GTCACCACCC AGCCCAGTTT 1140 | | AGCAAATGCT GGTGA 1155 |
|
| Domain Profile | S: 1 yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkelkhkni 60 | y +lek+geG+y++vyk+ ++ +g++vAlK i ++ e egvp+ta+rE sllk lkh+ni | Q: 52 YLNLEKLGEGSYATVYKGISRINGQLVALKVISMNAE-EGVPFTAIREASLLKGLKHANI 110 | 6789******************************998.9********************* |
| S: 61 vkLlevvakdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqlleglaylHsnk 120 | v L+++++ +k++l++vfe++++dL++++++++ +l++++v+ +++qll+glay+H+++ | Q: 111 VLLHDIIH-TKETLTFVFEYMHTDLAQYMSQHPG-GLHPHNVRLFMFQLLRGLAYIHHQH 168 | ********.99***********************.************************* |
| S: 121 ilHRDlKpqNlLiskegklklaDfGlarafssplktytkevvTlwYraPelLlgakeYst 180 | +lHRDlKpqNlLis+ g+lklaDfGlara s p++ty++evvTlwYr+P+ Llga+eYs+ | Q: 169 VLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEYSS 228 | ************************************************************ |
| S: 181 avDiWsvgcilaelltrkplfqgkse.idqlerifkllgtpsekvwpevsklpeyk.ksf 238 | ++DiW++gci+ e+++ +plf+g s+ +qle+i+++lg p+e++wp+vsklp+y+ + f | Q: 229 ELDIWGAGCIFIEMFQGQPLFPGVSNiLEQLEKIWEVLGVPTEDTWPGVSKLPNYNpEWF 288 | ***********************99967****************************8889 |
| S: 239 pkkkkkklkekvkklk..ekaldllekllaldpkkRisakealqhkyf 284 | p ++++l+ ++++l +a dl +++l+ p++R+sa+eal h+yf | Q: 289 PLPTPRSLHVVWNRLGrvPEAEDLASQMLKGFPRDRVSAQEALVHDYF 336 | 999999******999965679**************************9 |
|
Domain Sequence
(FASTA) | | YLNLEKLGEG SYATVYKGIS RINGQLVALK VISMNAEEGV PFTAIREASL LKGLKHANIV 60 | | LLHDIIHTKE TLTFVFEYMH TDLAQYMSQH PGGLHPHNVR LFMFQLLRGL AYIHHQHVLH 120 | | RDLKPQNLLI SHLGELKLAD FGLARAKSIP SQTYSSEVVT LWYRPPDALL GATEYSSELD 180 | | IWGAGCIFIE MFQGQPLFPG VSNILEQLEK IWEVLGVPTE DTWPGVSKLP NYNPEWFPLP 240 | | TPRSLHVVWN RLGRVPEAED LASQMLKGFP RDRVSAQEAL VHDYF 285 |
|
| Keyword | Alternative splicing; ATP-binding; Complete proteome; Kinase; Magnesium; Metal-binding; Nucleotide-binding; Polymorphism; Reference proteome; Serine/threonine-protein kinase; Transferase. |
| Sequence Source | Ensembl |
| Orthology | |
| Gene Ontology | |
| KEGG | |
| InterPros | |
| Pfam | |
| SMARTs | |
| Prosites | |
| Prints | |
| Created Date | 20-Feb-2013 |