EKS-HOS-00515

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-HOS-00515

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Atypical/H11	N/A	N/A	N/A	N/A	N/A

Status

Reviewed

Ensembl Protein

ENSP00000281938

UniProt Accession

Q9UJY1; B2R6A6; Q6FIH3; Q9UKS3;

Protein Name

Heat shock protein beta-8

Protein Synonyms/Alias

HspB8; Alpha-crystallin C chain; E2-induced gene 1 protein; Protein kinase H11; Small stress protein-like protein HSP22;

Gene Name

HSPB8

Gene Synonyms/Alias

HSPB8; CRYAC, E2IG1, HSP22; PP1629;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSG00000152137	ENSP00000441541	ENST00000541798
ENSG00000152137	ENSP00000281938	ENST00000281938

Organism

Homo sapiens

Functional Description

Displays temperature-dependent chaperone activity.

Protein Length

196

Protein Sequence
(FASTA)

MADGQMPFSC HYPSRLRRDP FRDSPLSSRL LDDGFGMDPF PDDLTASWPD WALPRLSSAW 60

PGTLRSGMVP RGPTATARFG VPAEGRTPPP FPGEPWKVCV NVHSFKPEEL MVKTKDGYVE 120

VSGKHEEKQQ EGGIVSKNFT KKIQLPAEVD PVTVFASLSP EGLLIIEAPQ VPPYSTFGES 180

SFNNELPQDS QEVTCT 196

Nucleotide Sequence
(FASTA)

ATGGCTGACG GTCAGATGCC CTTCTCCTGC CACTACCCAA GCCGCCTGCG CCGAGACCCC 60

TTCCGGGACT CTCCCCTCTC CTCTCGCCTG CTGGATGATG GCTTTGGCAT GGACCCCTTC 120

CCAGACGACT TGACAGCCTC TTGGCCCGAC TGGGCTCTGC CTCGTCTCTC CTCCGCCTGG 180

CCAGGCACCC TAAGGTCGGG CATGGTGCCC CGGGGCCCCA CTGCCACCGC CAGGTTTGGG 240

GTGCCTGCCG AGGGCAGGAC CCCCCCACCC TTCCCTGGGG AGCCCTGGAA AGTGTGTGTG 300

AATGTGCACA GCTTCAAGCC AGAGGAGTTG ATGGTGAAGA CCAAAGATGG ATACGTGGAG 360

GTGTCTGGCA AACATGAAGA GAAACAGCAA GAAGGTGGCA TTGTTTCTAA GAACTTCACA 420

AAGAAAATCC AGCTTCCTGC AGAGGTGGAT CCTGTGACAG TATTTGCCTC ACTTTCCCCA 480

GAGGGTCTGC TGATCATCGA AGCTCCCCAG GTCCCTCCTT ACTCAACATT TGGAGAGAGC 540

AGTTTCAACA ACGAGCTTCC CCAGGACAGC CAGGAAGTCA CCTGTACCTG A 591

Domain Profile

N/A

Domain Sequence
(FASTA)

N/A

Keyword

Chaperone; Charcot-Marie-Tooth disease; Complete proteome; Cytoplasm; Disease mutation; Neurodegeneration; Neuropathy; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Stress response.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>