| Tag | Content |
|---|
| EKPD ID | EKS-HOS-00015 |
| Classification | | Group/Family | Score | E-Value | Start | End | Domain Length |
|---|
| CAMK/PHK | 527.8 | 2.7E-158 | 20 | 288 | 269 |
|
| Status | Reviewed |
| Ensembl Protein | ENSP00000297373 |
| UniProt Accession | Q16816; B7Z1D0; F5H2S1; Q75LP5; |
| Protein Name | Phosphorylase b kinase gamma catalytic chain, skeletal muscle isoform |
| Protein Synonyms/Alias | Phosphorylase kinase subunit gamma-1; |
| Gene Name | PHKG1 |
| Gene Synonyms/Alias | PHKG1; PHKG; |
| Ensembl Information | |
| Organism | Homo sapiens |
| Functional Description | Phosphorylase b kinase catalyzes the phosphorylation ofserine in certain substrates, including troponin I. |
| Protein Length | 387 |
Protein Sequence
(FASTA) | | MTRDEALPDS HSAQDFYENY EPKEILGRGV SSVVRRCIHK PTSQEYAVKV IDVTGGGSFS 60 | | PEEVRELREA TLKEVDILRK VSGHPNIIQL KDTYETNTFF FLVFDLMKRG ELFDYLTEKV 120 | | TLSEKETRKI MRALLEVICT LHKLNIVHRD LKPENILLDD NMNIKLTDFG FSCQLEPGER 180 | | LREVCGTPSY LAPEIIECSM NEDHPGYGKE VDMWSTGVIM YTLLAGSPPF WHRKQMLMLR 240 | | MIMSGNYQFG SPEWDDYSDT VKDLVSRFLV VQPQNRYTAE EALAHPFFQQ YLVEEVRHFS 300 | | PRGKFKVIAL TVLASVRIYY QYRRVKPVTR EIVIRDPYAL RPLRRLIDAY AFRIYGHWVK 360 | | KGQQQNRAAL FENTPKAVLL SLAEEDY 387 |
|
Nucleotide Sequence
(FASTA) | | ATGACCCGGG ACGAGGCACT GCCGGACTCT CATTCTGCAC AGGACTTCTA TGAGAATTAT 60 | | GAGCCCAAAG AGATCCTGGG CAGGGGCGTT AGCAGTGTGG TCAGGCGATG CATCCACAAG 120 | | CCCACGAGCC AGGAGTACGC CGTGAAGGTC ATCGACGTCA CCGGTGGAGG CAGCTTCAGC 180 | | CCGGAGGAGG TGCGGGAGCT GCGAGAAGCC ACGCTGAAGG AGGTGGACAT CCTGCGCAAG 240 | | GTCTCAGGGC ACCCCAACAT CATACAGCTG AAGGACACTT ATGAGACCAA CACTTTCTTC 300 | | TTCTTGGTGT TTGACCTGAT GAAGAGAGGG GAGCTCTTTG ACTACCTCAC TGAGAAGGTC 360 | | ACCTTGAGTG AGAAGGAAAC CAGAAAGATC ATGCGAGCTC TGCTGGAGGT GATCTGCACC 420 | | TTGCACAAAC TCAACATCGT GCACCGGGAC CTGAAGCCCG AGAACATTCT CTTGGATGAC 480 | | AACATGAACA TCAAGCTCAC AGACTTTGGC TTTTCCTGCC AGCTGGAGCC GGGAGAGAGG 540 | | CTGCGAGAGG TCTGCGGGAC CCCCAGTTAC CTGGCCCCTG AGATTATCGA GTGCTCCATG 600 | | AATGAGGACC ACCCGGGCTA CGGGAAAGAG GTGGACATGT GGAGCACTGG CGTCATCATG 660 | | TACACGCTGC TGGCCGGCTC CCCGCCCTTC TGGCACCGGA AGCAGATGCT GATGCTGAGG 720 | | ATGATCATGA GCGGCAACTA CCAGTTTGGC TCGCCCGAGT GGGATGATTA CTCGGACACC 780 | | GTGAAGGACC TGGTCTCCCG ATTCCTGGTG GTGCAACCCC AGAACCGCTA CACAGCGGAA 840 | | GAGGCCTTGG CACACCCCTT CTTCCAGCAG TACTTGGTGG AGGAAGTGCG GCACTTCAGC 900 | | CCCCGGGGGA AGTTCAAGGT GATCGCTCTG ACCGTGCTGG CTTCAGTGCG GATCTACTAC 960 | | CAGTACCGCC GGGTGAAGCC TGTGACCCGG GAGATCGTCA TCCGAGACCC CTATGCCCTC 1020 | | CGGCCTCTGC GCCGGCTCAT CGACGCCTAC GCTTTCCGAA TCTATGGCCA CTGGGTGAAG 1080 | | AAGGGGCAGC AGCAGAACCG GGCAGCCCTT TTCGAGAACA CACCCAAGGC CGTGCTCCTC 1140 | | TCCCTGGCCG AGGAGGACTA CTGA 1164 |
|
| Domain Profile | S: 1 yepkeilGrGvssvvrrciekatgqefavkiidvs.aeklseeevkelreatlkeveilr 59 | yepkeilGrGvssvvrrci+k+t+qe+avk+idv+ ++++s+eev+elreatlkev+ilr | Q: 20 YEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTgGGSFSPEEVRELREATLKEVDILR 79 | 9**********************************899********************** |
| S: 60 qvsGhpsiiklkdvyesssflflvfdlmkkGelfdyltekvtlseketrkimralleave 119 | +vsGhp+ii+lkd+ye+++f+flvfdlmk+Gelfdyltekvtlseketrkimralle+++ | Q: 80 KVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRALLEVIC 139 | ************************************************************ |
| S: 120 ylhaknivhrdlkpenillddneniklsdfGfstqleeGeklrelcGtpgylapeilkcs 179 | +lh+ nivhrdlkpenillddn+nikl+dfGfs+qle+Ge+lre+cGtp+ylapei++cs | Q: 140 TLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGERLREVCGTPSYLAPEIIECS 199 | ************************************************************ |
| S: 180 mdeeapGyskevdlwalGvilytllaGsppfwhrkqllmlrlimeGkyqftspewddise 239 | m+e++pGy+kevd+w++Gvi+ytllaGsppfwhrkq+lmlr+im+G+yqf+spewdd+s+ | Q: 200 MNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWDDYSD 259 | ************************************************************ |
| S: 240 evkdliskllvvdpekrltaeealahpff 268 | +vkdl+s++lvv+p++r+taeealahpff | Q: 260 TVKDLVSRFLVVQPQNRYTAEEALAHPFF 288 | ****************************8 |
|
Domain Sequence
(FASTA) | | YEPKEILGRG VSSVVRRCIH KPTSQEYAVK VIDVTGGGSF SPEEVRELRE ATLKEVDILR 60 | | KVSGHPNIIQ LKDTYETNTF FFLVFDLMKR GELFDYLTEK VTLSEKETRK IMRALLEVIC 120 | | TLHKLNIVHR DLKPENILLD DNMNIKLTDF GFSCQLEPGE RLREVCGTPS YLAPEIIECS 180 | | MNEDHPGYGK EVDMWSTGVI MYTLLAGSPP FWHRKQMLML RMIMSGNYQF GSPEWDDYSD 240 | | TVKDLVSRFL VVQPQNRYTA EEALAHPFF 269 |
|
| Keyword | Alternative splicing; ATP-binding; Calmodulin-binding; Carbohydrate metabolism; Complete proteome; Glycogen metabolism; Kinase; Muscle protein; Nucleotide-binding; Polymorphism; Reference proteome; Serine/threonine-protein kinase; Transferase. |
| Sequence Source | Ensembl |
| Orthology | |
| Gene Ontology | |
| KEGG | |
| InterPros | |
| Pfam | |
| SMARTs | |
| Prosites | |
| Prints | |
| Created Date | 20-Feb-2013 |