| Tag | Content |
|---|
| EKPD ID | EPS-HOS-00007 |
| Classification | | Group/Family | Score | E-Value | Start | End | Domain Length |
|---|
| DSP/aDSP | 157.2 | 1.3E-45 | 23 | 160 | 138 |
|
| Status | Reviewed |
| Ensembl Protein | ENSP00000343244 |
| UniProt Accession | Q9H596; Q0VDA6; Q6IAJ6; Q6YDQ8; |
| Protein Name | Dual specificity protein phosphatase 21 |
| Protein Synonyms/Alias | Low molecular weight dual specificity phosphatase 21; LMW-DSP21; |
| Gene Name | DUSP21 |
| Gene Synonyms/Alias | DUSP21; LMWDSP21; |
| Ensembl Information | |
| Organism | Homo sapiens |
| Functional Description | Can dephosphorylate single and diphosphorylatedsynthetic MAPK peptides, with preference for the phosphotyrosine and diphosphorylated forms over phosphothreonine. |
| Protein Length | 190 |
Protein Sequence
(FASTA) | | MTASASSFSS SQGVQQPSIY SFSQITRSLF LSNGVAANDK LLLSSNRITA IVNASVEVVN 60 | | VFFEGIQYIK VPVTDARDSR LYDFFDPIAD LIHTIDMRQG RTLLHCMAGV SRSASLCLAY 120 | | LMKYHSMSLL DAHTWTKSRR PIIRPNNGFW EQLINYEFKL FNNNTVRMIN SPVGNIPDIY 180 | | EKDLRMMISM 190 |
|
Nucleotide Sequence
(FASTA) | | ATGACAGCAT CCGCGTCCTC CTTTTCATCA TCTCAGGGTG TCCAGCAGCC CTCCATCTAC 60 | | AGCTTCTCCC AAATAACCAG AAGCTTGTTT CTCAGCAATG GTGTGGCCGC CAACGACAAA 120 | | CTCCTTCTGT CCAGCAATCG CATCACCGCC ATTGTCAATG CCTCGGTGGA AGTGGTCAAC 180 | | GTATTCTTCG AGGGCATTCA GTACATAAAG GTGCCTGTTA CCGATGCTCG TGACTCGCGT 240 | | CTCTACGACT TTTTTGACCC CATTGCTGAT CTTATCCACA CCATCGATAT GAGGCAGGGC 300 | | CGTACGCTGC TGCACTGCAT GGCTGGAGTG AGCCGTTCCG CCTCACTGTG CCTTGCGTAC 360 | | CTCATGAAAT ACCACTCCAT GTCGCTGCTG GACGCCCATA CATGGACCAA GTCGCGCCGC 420 | | CCCATCATCC GGCCCAACAA CGGCTTTTGG GAACAGCTCA TCAATTACGA ATTCAAGCTG 480 | | TTTAATAACA ACACCGTGCG CATGATCAAC TCGCCGGTAG GTAACATCCC TGACATCTAT 540 | | GAGAAGGACC TACGTATGAT GATATCAATG TAA 573 |
|
| Domain Profile | S: 3 teilpglylgdqataldrreLsklgitvvinaslsvikvqviPeylikkgityknipvdD 62 | ++i+ +l+l++ a+d++ Ls + it ++nas++v++ ++ +gi+y ++pv D | Q: 23 SQITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVN-------VFFEGIQYIKVPVTD 75 | 799***********************************.......889************ |
| S: 63 sdvtdllqyfdeaaefideakekggkvlvHCaaGvsRSatlvlaYLmkveglslsdAiea 122 | + ++ l+++fd++a++i+ + +++g++l+HC aGvsRSa l+laYLmk++ +sl dA+++ | Q: 76 ARDSRLYDFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLAYLMKYHSMSLLDAHTW 135 | ************************************************************ |
| S: 123 vkrkrpsiepnegfleQLlelekkl 147 | +k++rp+i+pn+gf+eQL+++e kl | Q: 136 TKSRRPIIRPNNGFWEQLINYEFKL 160 | **********************998 |
|
Domain Sequence
(FASTA) | | SQITRSLFLS NGVAANDKLL LSSNRITAIV NASVEVVNVF FEGIQYIKVP VTDARDSRLY 60 | | DFFDPIADLI HTIDMRQGRT LLHCMAGVSR SASLCLAYLM KYHSMSLLDA HTWTKSRRPI 120 | | IRPNNGFWEQ LINYEFKL 138 |
|
| Keyword | Complete proteome; Cytoplasm; Hydrolase; Membrane; Mitochondrion; Mitochondrion inner membrane; Nucleus; Polymorphism; Protein phosphatase; Reference proteome. |
| Sequence Source | Ensembl |
| Orthology | |
| Gene Ontology | |
| KEGG | |
| InterPros | |
| Pfam | |
| SMARTs | |
| Prosites | |
| Prints | |
| Created Date | 20-Feb-2013 |