| Tag | Content |
|---|
| EKPD ID | EPS-HOS-00001 |
| Classification | | Group/Family | Score | E-Value | Start | End | Domain Length |
|---|
| PPM/PP2C | 54.9 | 5.9E-14 | 74 | 296 | 223 |
|
| Status | Reviewed |
| Ensembl Protein | ENSP00000346255 |
| UniProt Accession | Q8NI37; B3KWC5; Q68DZ7; Q6UY82; |
| Protein Name | Protein phosphatase PTC7 homolog |
| Protein Synonyms/Alias | T-cell activation protein phosphatase 2C; TA-PP2C; T-cell activation protein phosphatase 2C-like; |
| Gene Name | PPTC7 |
| Gene Synonyms/Alias | PPTC7; TAPP2C; |
| Ensembl Information | |
| Organism | Homo sapiens |
| Functional Description | |
| Protein Length | 304 |
Protein Sequence
(FASTA) | | MFSVLSYGRL VARAVLGGLS QTDPRAGGGG GGDYGLVTAG CGFGKDFRKG LLKKGACYGD 60 | | DACFVARHRS ADVLGVADGV GGWRDYGVDP SQFSGTLMRT CERLVKEGRF VPSNPIGILT 120 | | TSYCELLQNK VPLLGSSTAC IVVLDRTSHR LHTANLGDSG FLVVRGGEVV HRSDEQQHYF 180 | | NTPFQLSIAP PEAEGVVLSD SPDAADSTSF DVQLGDIILT ATDGLFDNMP DYMILQELKK 240 | | LKNSNYESIQ QTARSIAEQA HELAYDPNYM SPFAQFACDN GLNVRGGKPD DITVLLSIVA 300 | | EYTD 304 |
|
Nucleotide Sequence
(FASTA) | | ATGTTCTCGG TCCTCTCGTA CGGGCGGCTG GTGGCCCGCG CCGTGCTCGG CGGCCTCTCG 60 | | CAGACCGACC CCAGGGCCGG CGGCGGCGGC GGCGGCGACT ACGGACTGGT GACGGCCGGC 120 | | TGCGGCTTCG GGAAGGACTT CCGTAAGGGC CTCCTCAAGA AGGGCGCGTG CTACGGGGAC 180 | | GACGCGTGCT TCGTGGCCCG GCACCGTTCC GCGGACGTGC TCGGGGTTGC AGATGGTGTA 240 | | GGAGGCTGGA GAGACTATGG AGTTGATCCA TCTCAATTCT CAGGGACTTT AATGCGGACG 300 | | TGTGAACGTT TAGTAAAAGA AGGACGGTTC GTACCTAGTA ATCCCATTGG AATTCTCACC 360 | | ACAAGCTACT GTGAGTTGCT GCAAAATAAA GTCCCTTTGC TCGGTAGCAG CACCGCCTGC 420 | | ATTGTGGTGC TGGACAGAAC CAGCCACCGC TTACACACAG CAAACCTGGG CGATTCAGGC 480 | | TTCCTGGTTG TCAGGGGTGG TGAAGTCGTG CACCGATCAG ATGAGCAGCA GCATTACTTC 540 | | AACACTCCAT TCCAGCTCTC AATCGCTCCC CCTGAAGCCG AGGGAGTCGT CTTGAGCGAC 600 | | AGTCCGGATG CTGCTGATAG CACGTCTTTC GATGTCCAGC TAGGAGACAT TATCCTGACG 660 | | GCAACAGATG GACTCTTTGA CAACATGCCT GATTATATGA TTCTTCAGGA GCTAAAAAAG 720 | | TTAAAGAATT CAAATTATGA GAGTATACAA CAGACTGCCA GAAGCATTGC TGAGCAAGCT 780 | | CATGAGCTGG CCTATGACCC AAATTATATG TCACCTTTTG CACAGTTTGC ATGTGACAAT 840 | | GGATTGAATG TGAGAGGTGG AAAGCCAGAT GACATCACCG TCCTTCTTTC AATAGTGGCT 900 | | GAGTATACAG ACTAG 915 |
|
| Domain Profile | S: 7 lvvgDvvG....hGleAalimgllrsalrelatagle.paevlerlnealarnleee... 58 | l+v+D+vG G++ + ++g l + ++l+++g p++ ++ l + ++ l+++ | Q: 74 LGVADGVGgwrdYGVDPSQFSGTLMRTCERLVKEGRFvPSNPIGILTTSYCELLQNKvpl 133 | 789*****99999*******************8886676666666666666667777666 |
| S: 59 erfatavlaeydpstgkleyanaGhpppllvrpdg...gtkfllvstglp..lGilpe.. 111 | ta+++++d +++l+ an+G++ +l+vr+ + + ++ + ++ p l+i p | Q: 134 LGSSTACIVVLDRTSHRLHTANLGDSGFLVVRGGEvvhRSDEQQHYFNTPfqLSIAPPea 193 | 7999*****************************556665555555566668999988899 |
| S: 112 .........adyeeaelqlepgdllllyTDGvtEardpdgelfgkerllallaeaegesl 162 | +++++++++ gd++l +TDG+++++ + l + l+ l+++ es | Q: 194 egvvlsdspDAADSTSFDVQLGDIILTATDGLFDNMPDYMIL----QELKKLKNSNYESI 249 | *******9999*************************555555....44444444445789 |
| S: 163 eelldalveelle....................lgsgeleDDitllv 189 | +++++++ e+++e + +g++ DDit+l+ | Q: 250 QQTARSIAEQAHElaydpnymspfaqfacdnglNVRGGKPDDITVLL 296 | *********************************8889********96 |
|
Domain Sequence
(FASTA) | | LGVADGVGGW RDYGVDPSQF SGTLMRTCER LVKEGRFVPS NPIGILTTSY CELLQNKVPL 60 | | LGSSTACIVV LDRTSHRLHT ANLGDSGFLV VRGGEVVHRS DEQQHYFNTP FQLSIAPPEA 120 | | EGVVLSDSPD AADSTSFDVQ LGDIILTATD GLFDNMPDYM ILQELKKLKN SNYESIQQTA 180 | | RSIAEQAHEL AYDPNYMSPF AQFACDNGLN VRGGKPDDIT VLL 223 |
|
| Keyword | Complete proteome; Hydrolase; Magnesium; Manganese; Metal-binding; Protein phosphatase; Reference proteome. |
| Sequence Source | Ensembl |
| Orthology | |
| Gene Ontology | |
| KEGG | |
| InterPros | |
| Pfam | |
| SMARTs | |
| Prosites | |
| Prints | |
| Created Date | 20-Feb-2013 |