EKS-HOS-00494

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-HOS-00494

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/RSKL	629.8	9.7E-189	153	539	387

Status

Reviewed

Ensembl Protein

ENSP00000351086

UniProt Accession

Q9Y6S9; A6NGM9; Q69YT9; Q6ZMQ6; Q96NR9; Q9BSU9;

Protein Name

Ribosomal protein S6 kinase-like 1

Protein Synonyms/Alias

Gene Name

RPS6KL1

Gene Synonyms/Alias

RPS6KL1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSG00000198208	ENSP00000450968	ENST00000553315
ENSG00000198208	ENSP00000450567	ENST00000557413
ENSG00000198208	ENSP00000351086	ENST00000358328
ENSG00000198208	ENSP00000450846	ENST00000553789
ENSG00000198208	ENSP00000450660	ENST00000555009
ENSG00000198208	ENSP00000346644	ENST00000354625
ENSG00000198208	ENSP00000452027	ENST00000555647
ENSG00000198208	ENSP00000451986	ENST00000555910
ENSG00000198208	ENSP00000451152	ENST00000553971
ENSG00000198208	ENSP00000451338	ENST00000556776
ENSG00000198208	ENSP00000451795	ENST00000556848

Organism

Homo sapiens

Functional Description

Protein Length

549

Protein Sequence
(FASTA)

MSLVACECLP SPGLEPEPCS RARSQAHVYL EQIRNRVALG VPDMTKRDYL VDAATQIRLA 60

LERDVSEDYE AAFNHYQNGV DVLLRGIHVD PNKERREAVK LKITKYLRRA EEIFNCHLQR 120

PLSSGASPSA GFSSLRLRPI RTLSSAVEQL RGCRVVGVIE KVQLVQDPAT GGTFVVKSLP 180

RCHMVSRERL TIIPHGVPYM TKLLRYFVSE DSIFLHLEHV QGGTLWSHLL SQAHSRHSGL 240

SSGSTQERMK AQLNPHLNLL TPARLPSGHA PGQDRIALEP PRTSPNLLLA GEAPSTRPQR 300

EAEGEPTART STSGSSDLPK APGGHLHLQA RRAGQNSDAG PPRGLTWVPE GAGPVLGGCG 360

RGMDQSCLSA DGAGRGCGRA TWSVREEQVK QWAAEMLVAL EALHEQGVLC RDLHPGNLLL 420

DQAGHIRLTY FGQWSEVEPQ CCGEAVDNLY SAPEVGGISE LTEACDWWSF GSLLYELLTG 480

MALSQSHPSG IQAHTQLQLP EWLSRPAASL LTELLQFEPT RRLGMGEGGV SKLKSHPFFS 540

TIQWSKLVG 549

Nucleotide Sequence
(FASTA)

ATGAGCCTGG TGGCCTGTGA GTGCCTGCCC AGCCCCGGCC TGGAGCCTGA GCCTTGCTCA 60

CGAGCACGGT CCCAAGCTCA CGTGTACCTG GAGCAGATTC GCAACAGGGT GGCTCTGGGA 120

GTGCCTGACA TGACAAAACG TGACTATCTG GTGGATGCGG CCACGCAGAT CCGGCTGGCC 180

CTGGAGCGCG ATGTTAGTGA GGACTATGAG GCGGCCTTCA ACCACTATCA GAATGGCGTG 240

GACGTGCTGC TCCGTGGCAT ACACGTTGAC CCCAACAAGG AGCGACGTGA GGCTGTGAAG 300

CTGAAAATTA CCAAATACCT GCGGCGGGCA GAGGAGATCT TCAACTGCCA CCTGCAGCGG 360

CCGCTGAGCA GTGGAGCCAG CCCCAGCGCG GGTTTCAGCA GCCTGAGGCT CCGGCCCATT 420

CGCACGCTGA GCTCTGCCGT GGAGCAGCTG AGGGGCTGCA GGGTGGTCGG GGTCATCGAG 480

AAGGTGCAGC TGGTCCAGGA CCCGGCAACC GGAGGGACCT TTGTGGTGAA GAGCCTACCC 540

AGGTGCCACA TGGTGAGCAG GGAGCGGCTG ACCATCATCC CACACGGAGT CCCCTACATG 600

ACGAAGCTGC TCAGGTACTT TGTGAGCGAG GACTCCATCT TCCTGCACCT GGAGCATGTG 660

CAAGGAGGCA CTCTCTGGTC CCACCTGCTC TCCCAGGCGC ACTCCCGACA TTCTGGGCTC 720

AGCTCTGGCT CTACCCAGGA GAGGATGAAG GCTCAGCTCA ACCCCCACCT CAACCTCCTG 780

ACCCCAGCGA GGCTTCCCTC AGGCCATGCC CCTGGCCAGG ACAGAATCGC CCTGGAGCCT 840

CCTAGGACTT CTCCGAACCT TCTCCTAGCT GGGGAGGCCC CATCCACCAG ACCCCAGAGG 900

GAGGCTGAAG GTGAACCCAC AGCCAGGACC AGCACCTCTG GCTCCTCGGA CCTTCCAAAG 960

GCCCCAGGTG GCCACCTGCA CCTTCAAGCT AGGAGGGCTG GCCAGAACTC AGACGCTGGG 1020

CCCCCTCGGG GGCTCACTTG GGTTCCTGAG GGGGCCGGCC CGGTGCTAGG GGGCTGTGGC 1080

CGAGGCATGG ATCAGAGCTG CCTGTCAGCA GATGGGGCCG GCCGGGGCTG TGGCAGGGCC 1140

ACCTGGAGTG TGAGAGAGGA GCAGGTGAAG CAGTGGGCGG CAGAGATGCT GGTAGCGCTG 1200

GAGGCGCTGC ACGAGCAGGG GGTGCTGTGC CGGGACCTCC ACCCCGGGAA CCTGCTCCTG 1260

GACCAGGCAG GTCACATCCG GCTCACATAT TTTGGCCAGT GGTCAGAGGT GGAGCCCCAG 1320

TGCTGCGGGG AGGCCGTGGA CAATCTCTAC AGCGCCCCAG AGGTGGGTGG GATTTCCGAG 1380

CTGACGGAAG CCTGTGACTG GTGGAGCTTT GGGTCTCTAC TGTATGAACT GCTGACGGGA 1440

ATGGCACTGT CCCAGAGCCA CCCTTCAGGA ATCCAGGCCC ACACCCAGCT CCAGCTGCCC 1500

GAGTGGCTCA GTCGCCCAGC GGCCTCTCTG CTGACTGAGC TGCTGCAGTT CGAGCCTACC 1560

CGGCGCCTGG GCATGGGAGA AGGTGGTGTC AGCAAACTCA AGTCCCATCC CTTTTTCAGT 1620

ACCATCCAAT GGAGCAAGCT GGTGGGGTAA 1650

Domain Profile

S: 1     crvvgilkkvqllvepvtgesfvvkslekeavassdrsiflPtnvPymvkLlryfesEek  60

         crvvg+++kvql+++p+tg++fvvksl++++++s++r++++P++vPym+kLlryf+sE++

Q: 153   CRVVGVIEKVQLVQDPATGGTFVVKSLPRCHMVSRERLTIIPHGVPYMTKLLRYFVSEDS  212

         9***********************************************************

S: 61    illlLefvegGtLwsfLldeaesrhadlrdGdtqekvkvqltkrllllvgvdlervvelr  120

         i+l+Le+v+gGtLws+Ll++a+srh++l++G+tqe++k+ql+++l+ll++++l+++++++

Q: 213   IFLHLEHVQGGTLWSHLLSQAHSRHSGLSSGSTQERMKAQLNPHLNLLTPARLPSGHAPG  272

         ************************************************************

S: 121   derislekprtesllllvgeeptsrsqreaeeesearvklefssdkskaprGn...rirr  177

         ++ri+le+prt+++lll+ge+p++r qreae+e++ar+++++ssd +kap+G+   ++rr

Q: 273   QDRIALEPPRTSPNLLLAGEAPSTRPQREAEGEPTARTSTSGSSDLPKAPGGHlhlQARR  332

         ************************************************************

S: 178   egqnsspssskeiklvsedadkslealsrgldkalqsvdka.lslrravwslpEelikqW  236

         +gqns++++++ +++v+e+a+++l+ ++rg+d+++ s+d a ++++ra+ws++Ee++kqW

Q: 333   AGQNSDAGPPRGLTWVPEGAGPVLGGCGRGMDQSCLSADGAgRGCGRATWSVREEQVKQW  392

         ************************************************************

S: 237   aaelvvaleaLHeegvlirDlnadniLldskGhllltYfgrwsevekscrreavdnlysA  296

         aae++valeaLHe+gvl+rDl+++n+Lld++Gh++ltYfg+wseve++c+ eavdnlysA

Q: 393   AAEMLVALEALHEQGVLCRDLHPGNLLLDQAGHIRLTYFGQWSEVEPQCCGEAVDNLYSA  452

         ************************************************************

S: 297   PEvgaiselteasDwWslGalLyelLtGkalaeahPsgiqahtelqlPevvSeeAkdLle  356

         PEvg+iseltea+DwWs+G+lLyelLtG+al+++hPsgiqaht+lqlPe++S++A++Ll+

Q: 453   PEVGGISELTEACDWWSFGSLLYELLTGMALSQSHPSGIQAHTQLQLPEWLSRPAASLLT  512

         ************************************************************

S: 357   eLLqfePalRlGaGeagvdelkaHPFF  383

         eLLqfeP++RlG+Ge+gv++lk+HPFF

Q: 513   ELLQFEPTRRLGMGEGGVSKLKSHPFF  539

         **************************9

Domain Sequence
(FASTA)

CRVVGVIEKV QLVQDPATGG TFVVKSLPRC HMVSRERLTI IPHGVPYMTK LLRYFVSEDS 60

IFLHLEHVQG GTLWSHLLSQ AHSRHSGLSS GSTQERMKAQ LNPHLNLLTP ARLPSGHAPG 120

QDRIALEPPR TSPNLLLAGE APSTRPQREA EGEPTARTST SGSSDLPKAP GGHLHLQARR 180

AGQNSDAGPP RGLTWVPEGA GPVLGGCGRG MDQSCLSADG AGRGCGRATW SVREEQVKQW 240

AAEMLVALEA LHEQGVLCRD LHPGNLLLDQ AGHIRLTYFG QWSEVEPQCC GEAVDNLYSA 300

PEVGGISELT EACDWWSFGS LLYELLTGMA LSQSHPSGIQ AHTQLQLPEW LSRPAASLLT 360

ELLQFEPTRR LGMGEGGVSK LKSHPFF 387

Keyword

Alternative splicing; ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Polymorphism; Reference proteome; Ribonucleoprotein; Ribosomal protein; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Xiphophorus maculatus"; ?>