EKS-HOS-00227

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-HOS-00227

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/NKF1	350.8	2.1E-104	43	304	262

Status

Unreviewed

Ensembl Protein

ENSP00000388220

UniProt Accession

H7BZ84;

Protein Name

Protein Synonyms/Alias

Putative uncharacterized serine/threonine-protein kinase SgK110;

Gene Name

SGK110

Gene Synonyms/Alias

SGK110;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSG00000231274	ENSP00000467263	ENST00000592464
ENSG00000231274	ENSP00000388220	ENST00000420723

Organism

Homo sapiens

Functional Description

Protein Length

423

Protein Sequence
(FASTA)

MERRASETPE DGDPEEDTAT ALQRLVELTT SRVTPVRSLR DQYHLIRKLG SGSYGRVLLA 60

QPHQGGPAVA LKLLRRDLVL RSTFLREFCV GRCVSAHPGL LQTLAGPLQT PRYFAFAQEY 120

APCGDLSGML QERGLPELLV KRVVAQLAGA LDFLHSRGLV HADVKPDNVL VFDPVCSRVA 180

LGDLGLTRPE GSPTPAPPVP LPTAPPELCL LLPPDTLPLR PAVDSWGLGV LLFCAATACF 240

PWDVALAPNP EFEAFAGWVT TKPQPPQPPP PWDQFAPPAL ALLQGLLDLD PETRSPPLAV 300

LDFLGDDWGL QGNREGPGFW GAPCPMRTGR REAQAWRSGQ MRVMTAKVVG GRGQMGELPD 360

QVTETGGQSL GQRPFPQPPG PPGWRDSCTR EDREGTHCTL PTERWAWTRI PLPTEDPRAQ 420

LLP 423

Nucleotide Sequence
(FASTA)

ATGGAGCGCA GGGCCTCCGA GACCCCTGAG GATGGGGACC CAGAGGAGGA CACAGCCACA 60

GCCCTCCAAC GGCTGGTGGA GCTGACGACC AGCAGGGTGA CCCCGGTGAG GAGCCTTCGG 120

GACCAGTACC ACCTCATCCG GAAGCTGGGC TCCGGCTCCT ACGGCCGCGT GCTCCTTGCC 180

CAGCCTCACC AGGGGGGTCC AGCTGTGGCT CTGAAGCTCC TGCGTCGGGA TTTGGTCCTG 240

AGAAGCACCT TCCTGAGGGA GTTCTGTGTG GGCCGCTGCG TCTCTGCACA CCCAGGCCTG 300

CTGCAGACCC TGGCAGGACC CCTACAGACC CCCCGCTATT TTGCCTTCGC CCAGGAGTAC 360

GCGCCCTGTG GGGACCTCAG CGGGATGCTG CAGGAAAGGG GCCTCCCAGA ACTGCTGGTG 420

AAGCGGGTGG TGGCCCAGTT GGCAGGAGCT CTGGACTTCC TCCACAGCCG GGGGCTGGTC 480

CACGCAGATG TCAAACCTGA CAACGTGCTG GTCTTCGACC CGGTCTGCAG CCGTGTGGCC 540

CTGGGAGACC TGGGTCTGAC CCGGCCAGAG GGCAGCCCGA CCCCCGCCCC ACCAGTGCCT 600

CTGCCCACGG CACCGCCTGA GCTCTGTCTC CTGCTACCGC CCGACACCCT GCCTCTGCGG 660

CCAGCCGTGG ACTCCTGGGG CCTGGGGGTG CTTCTCTTCT GTGCTGCCAC TGCCTGTTTC 720

CCTTGGGACG TGGCACTGGC CCCCAACCCT GAGTTCGAGG CCTTCGCTGG CTGGGTGACC 780

ACCAAGCCTC AGCCACCTCA GCCACCACCA CCCTGGGACC AGTTTGCGCC CCCAGCCCTG 840

GCCTTGCTCC AGGGGCTTCT GGACCTGGAT CCCGAGACTA GGAGCCCCCC ACTGGCTGTC 900

CTGGACTTCC TGGGGGACGA CTGGGGGTTG CAAGGGAACA GAGAGGGACC TGGGTTTTGG 960

GGAGCGCCGT GTCCTATGAG GACAGGGAGG AGGGAGGCTC AAGCCTGGAG GAGTGGACAG 1020

ATGAGGGTGA TGACAGCAAA AGTGGTGGGA GGACGGGGAC AGATGGGGGA GCTCCCTGAC 1080

CAGGTGACAG AGACAGGTGG CCAGAGCCTG GGCCAGAGGC CCTTCCCCCA GCCCCCAGGG 1140

CCACCTGGAT GGAGAGACAG CTGCACCCGG GAGGACAGAG AGGGAACACA TTGCACTCTC 1200

CCTACGGAAC GCTGGGCTTG GACGCGCATT CCTCTTCCAA CTGAGGACCC AAGAGCCCAG 1260

CTCCTGCCC 1269

Domain Profile

S: 1     yelvrklgeGsfgkvlLvehrqsgtkvalKllpkektklkdFlrEfsvglslsshsaivk  60

         y+l+rklg+Gs+g+vlL++++q+g +valKll+++ + +++FlrEf+vg+++s+h+ +++

Q: 43    YHLIRKLGSGSYGRVLLAQPHQGGPAVALKLLRRDLVLRSTFLREFCVGRCVSAHPGLLQ  102

         99**********************************************************

S: 61    tydvaletadayvFaqEyaplgdLaeaiqekvGlpeaavkrvvaqlasAldflHsrnlvh  120

         t++++l+t+++++FaqEyap+gdL++++qe+ Glpe  vkrvvaqla+AldflHsr+lvh

Q: 103   TLAGPLQTPRYFAFAQEYAPCGDLSGMLQER-GLPELLVKRVVAQLAGALDFLHSRGLVH  161

         *******************************.****************************

S: 121   rdlKpenvLvfdpdcsrvkltDfGltrkkgslvkkkeevipytapelcelvkeeklkvdp  180

         +d+Kp+nvLvfdp csrv+l+D+Gltr++gs++++  +++p+++pelc l ++++l+++p

Q: 162   ADVKPDNVLVFDPVCSRVALGDLGLTRPEGSPTPAPPVPLPTAPPELCLLLPPDTLPLRP  221

         ************************************************************

S: 181   svDvWalGvllfvvltgkfPWdkasleadpfyeeflkwqkr..klrklPkkfkrlsekal  238

         +vD+W lGvllf++ t++fPWd a l+ +p++e+f+ w +   ++++ P ++++++++al

Q: 222   AVDSWGLGVLLFCAATACFPWDVA-LAPNPEFEAFAGWVTTkpQPPQPPPPWDQFAPPAL  280

         ************************.9*************4436999**************

S: 239   rllkklldlepedrskakevakfl  262

         +ll++lldl+pe+rs+  +v +fl

Q: 281   ALLQGLLDLDPETRSPPLAVLDFL  304

         ********************9987

Domain Sequence
(FASTA)

YHLIRKLGSG SYGRVLLAQP HQGGPAVALK LLRRDLVLRS TFLREFCVGR CVSAHPGLLQ 60

TLAGPLQTPR YFAFAQEYAP CGDLSGMLQE RGLPELLVKR VVAQLAGALD FLHSRGLVHA 120

DVKPDNVLVF DPVCSRVALG DLGLTRPEGS PTPAPPVPLP TAPPELCLLL PPDTLPLRPA 180

VDSWGLGVLL FCAATACFPW DVALAPNPEF EAFAGWVTTK PQPPQPPPPW DQFAPPALAL 240

LQGLLDLDPE TRSPPLAVLD FL 262

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Felis catus"; ?>Gorilla gorilla"; ?>Ictidomys tridecemlineatus"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Ornithorhynchus anatinus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Rattus norvegicus"; ?>