EKS-GAA-00284

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GAA-00284

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/MAPKAPK	427.5	2.4E-128	51	312	262

Status

Unreviewed

Ensembl Protein

ENSGACP00000000505

UniProt Accession

G3N5D5;

Protein Name

Protein Synonyms/Alias

Gene Name

MAPKAPK2

Gene Synonyms/Alias

MAPKAPK2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGACG00000000388	ENSGACP00000000505	ENSGACT00000000505

Organism

Gasterosteus aculeatus

Functional Description

Protein Length

389

Protein Sequence
(FASTA)

MLSNAQNQPL FPNPSGQQNP GGQQNTTGQF LPFHARPSLQ IKKNAITDDY KVTSQVLGLG 60

INGKVLEIFQ KKTGDKYALK MLQDCAKARR EVELHWRASP CANIVRIIDV YENLYQSRKC 120

LLIVMECMDG GELFSRIQDR GDQAFTEREA SDIMKNIGEA IQFLHAVNIA HRDVKPENLL 180

YSSKRPNALL KLTDFGFAKE TTSHNSLATP CYTPYYVAPE VLGPEKYDKS CDMWSLGVIM 240

YILLCGYPPF YSNHGLAISP GMKKRIRMGQ YEFPNPEWSD VSEEAKQLIR TLLKTEPTQR 300

MTITEFMNNP WINQSMEVPQ TPLHTSRVLK EEKDAWEDVK EEMTSALATM RVDYEQIKIK 360

TIEDSTNPLL TKRRKKASHS MPDPQSAAH 389

Nucleotide Sequence
(FASTA)

ATGCTGTCCA ACGCTCAGAA CCAGCCACTG TTTCCCAACC CGTCGGGGCA GCAGAACCCG 60

GGCGGGCAGC AGAACACTAC AGGCCAGTTC CTCCCCTTCC ACGCTCGACC CTCCTTACAG 120

ATCAAGAAGA ATGCCATAAC AGACGACTAC AAGGTAACCA GCCAGGTGCT GGGGCTGGGC 180

ATCAACGGCA AGGTGCTGGA GATCTTCCAG AAGAAGACCG GAGACAAGTA TGCGCTGAAG 240

ATGCTGCAGG ATTGTGCCAA GGCCCGTAGG GAAGTGGAGC TGCACTGGAG GGCTTCTCCC 300

TGTGCCAACA TTGTGCGCAT CATTGATGTC TATGAGAACC TCTATCAGAG CAGGAAGTGT 360

CTGCTTATTG TCATGGAGTG CATGGATGGT GGTGAGCTTT TTAGTCGAAT CCAGGACAGA 420

GGAGATCAGG CCTTCACAGA GCGAGAGGCG TCTGACATCA TGAAAAACAT CGGCGAGGCC 480

ATTCAGTTCC TGCATGCCGT CAACATTGCT CACAGAGACG TCAAGCCAGA GAACTTACTG 540

TATTCCTCAA AGAGGCCCAA CGCCCTGCTC AAACTCACAG ATTTTGGCTT TGCCAAGGAA 600

ACCACCTCCC ACAACTCTTT AGCTACTCCG TGCTACACCC CCTACTATGT TGCTCCAGAA 660

GTTCTTGGCC CAGAGAAATA TGACAAGTCA TGTGACATGT GGTCACTGGG TGTCATTATG 720

TATATCCTGT TGTGTGGATA CCCTCCTTTT TATTCAAACC ACGGTTTAGC CATCTCTCCT 780

GGGATGAAGA AGAGGATCAG GATGGGCCAA TATGAGTTTC CAAACCCTGA GTGGTCTGAC 840

GTATCAGAGG AAGCAAAACA ACTGATTAGG ACTCTCCTTA AGACTGAGCC AACGCAGAGG 900

ATGACCATCA CCGAATTCAT GAATAATCCC TGGATCAATC AATCGATGGA GGTTCCCCAG 960

ACCCCACTTC ACACCAGCCG GGTGCTAAAG GAGGAGAAGG ACGCGTGGGA GGATGTCAAG 1020

GAGGAAATGA CCAGTGCCTT GGCAACAATG AGAGTCGACT ACGAGCAAAT CAAGATCAAG 1080

ACCATTGAGG ACTCGACCAA TCCCCTGCTA ACAAAAAGGA GAAAGAAAGC CAGTCACTCC 1140

ATGCCGGACC CCCAATCTGC TGCCCACTGA 1170

Domain Profile

S: 1     klteevlGeGisgkvlecvkkktgekyalkilkdrkkvrrevelhvqasghknivelidv  60

         k+t++vlG Gi+gkvle+++kktg+kyalk+l+d++k+rrevelh++as + niv++idv

Q: 51    KVTSQVLGLGINGKVLEIFQKKTGDKYALKMLQDCAKARREVELHWRASPCANIVRIIDV  110

         5799********************************************************

S: 61    fensfedekrlllvlekleGGellsriqer..kaftekeasevvkdiasalkflhsknia  118

         +en ++ +k+ll+v+e+++GGel+sriq+r  +afte+eas+++k+i++a++flh  nia

Q: 111   YENLYQSRKCLLIVMECMDGGELFSRIQDRgdQAFTEREASDIMKNIGEAIQFLHAVNIA  170

         *******************************9****************************

S: 119   hrDlkpenlLyeskeknapvklcDfglaketeeeeelktpcltaeyvaPevleaekeeal  178

         hrD+kpenlLy+sk+ na +kl+Dfg+aket+++++l+tpc+t++yvaPevl++ek

Q: 171   HRDVKPENLLYSSKRPNALLKLTDFGFAKETTSHNSLATPCYTPYYVAPEVLGPEK----  226

         ********************************************************....

S: 179   lydksCDlWslGvilyillcGypPfyskkgraiskklkeriqegkyefPeeeWsevseea  238

          ydksCD+WslGvi+yillcGypPfys++g ais+++k+ri++g+yefP++eWs+vseea

Q: 227   -YDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKKRIRMGQYEFPNPEWSDVSEEA  285

         .***********************************************************

S: 239   kdlirklLkrdpkerltieevlnhpwv  265

         k+lir+lLk++p++r+ti+e++n+pw+

Q: 286   KQLIRTLLKTEPTQRMTITEFMNNPWI  312

         **************************8

Domain Sequence
(FASTA)

KVTSQVLGLG INGKVLEIFQ KKTGDKYALK MLQDCAKARR EVELHWRASP CANIVRIIDV 60

YENLYQSRKC LLIVMECMDG GELFSRIQDR GDQAFTEREA SDIMKNIGEA IQFLHAVNIA 120

HRDVKPENLL YSSKRPNALL KLTDFGFAKE TTSHNSLATP CYTPYYVAPE VLGPEKYDKS 180

CDMWSLGVIM YILLCGYPPF YSNHGLAISP GMKKRIRMGQ YEFPNPEWSD VSEEAKQLIR 240

TLLKTEPTQR MTITEFMNNP WI 262

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013