EKS-GAA-00088

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GAA-00088

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	335.5	3.2E-100	4	288	285

Status

Unreviewed

Ensembl Protein

ENSGACP00000001045

UniProt Accession

G3N6W7;

Protein Name

Protein Synonyms/Alias

Gene Name

CDK20

Gene Synonyms/Alias

CDK20;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGACG00000000810	ENSGACP00000001042	ENSGACT00000001042
ENSGACG00000000810	ENSGACP00000001045	ENSGACT00000001045

Organism

Gasterosteus aculeatus

Functional Description

Protein Length

339

Protein Sequence
(FASTA)

MEEYSILGRI GEGAHGIVFK AKHIETGETV ALKKVALRRL EDGIPNQALR EIKALQEIED 60

NQHVVKLKDV FPHGTGFVLV FDFMLSDLSE VIRNFQQPLT PAQVKGYMMM LLKGVAFLHH 120

NNIMHRDLKP ANLLISSSGH LKIADFGLAR LFTEQEDRLY SHQVATRWYR APELLYGARK 180

YDEGVDLWAV GCIFGELLNL SPLFPGENDI EQLCCVLRVL GTPTEDSWPE IVELPDYNKI 240

TFKENPAIPL EQIVPDSSPQ AVDLLYNFLV YPSYRRCSAR QALLHPFFFS SPIPAHHSEL 300

PIPERGGRLP HQRLQAPPSD FSVDLPLHCS MVDPALLRG 339

Nucleotide Sequence
(FASTA)

ATGGAGGAGT ACAGTATTCT TGGTCGGATC GGTGAAGGAG CTCACGGCAT CGTCTTCAAG 60

GCCAAACACA TTGAGACTGG AGAGACAGTA GCTCTGAAAA AAGTGGCTCT GAGGCGGCTG 120

GAGGACGGCA TTCCCAACCA GGCTCTGAGG GAGATTAAGG CCCTGCAGGA GATCGAAGAC 180

AACCAGCATG TGGTGAAGCT GAAGGACGTC TTCCCTCACG GGACGGGCTT CGTGCTGGTG 240

TTTGACTTCA TGCTGTCTGA CCTCTCTGAG GTGATCAGGA ACTTCCAGCA ACCTTTGACC 300

CCGGCTCAGG TCAAAGGTTA CATGATGATG CTGCTGAAGG GCGTGGCCTT CCTGCATCAC 360

AACAACATCA TGCACCGAGA CCTGAAGCCA GCAAACCTCC TCATCAGCTC TTCGGGTCAT 420

CTGAAAATTG CAGACTTTGG TTTGGCGAGA TTGTTCACTG AGCAGGAAGA CAGACTGTAC 480

AGCCACCAGG TGGCCACCAG GTGGTACAGA GCCCCTGAGC TGCTGTATGG TGCCAGAAAG 540

TACGACGAAG GAGTTGATCT GTGGGCGGTG GGCTGTATTT TCGGGGAGCT GCTGAACTTG 600

TCTCCTCTGT TTCCTGGTGA AAACGATATC GAACAGCTCT GCTGTGTCCT CCGAGTGCTG 660

GGGACACCGA CTGAGGACAG CTGGCCTGAG ATTGTGGAGT TGCCAGATTA CAATAAAATC 720

ACCTTCAAGG AGAATCCAGC GATCCCATTG GAGCAGATCG TCCCGGACTC TTCCCCTCAG 780

GCCGTCGACC TGCTCTACAA CTTCCTGGTT TATCCGTCCT ACCGACGCTG CTCTGCTCGA 840

CAGGCTCTCC TCCATCCCTT CTTCTTCTCC TCTCCTATTC CTGCTCACCA CTCAGAGCTT 900

CCCATTCCTG AGAGGGGGGG TCGACTCCCC CACCAGCGGC TGCAGGCTCC ACCCAGCGAC 960

TTCTCAGTGG ACCTTCCTCT GCATTGCAGC ATGGTAGACC CTGCCCTGCT GCGGGGT 1017

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkel.khkn  59

         y+ l +igeG++g v+kak+ etge+vAlKk++l + ++g+p +alrEi+ l+e+ ++++

Q: 4     YSILGRIGEGAHGIVFKAKHIETGETVALKKVALRRLEDGIPNQALREIKALQEIeDNQH  63

         778899*************************************************7899*

S: 60    ivkLlevvakdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqlleglaylHsn  119

         +vkL++v+  + + ++Lvf+f+ +dL++++++ ++  l++++vk ++++ll+g+a+lH+n

Q: 64    VVKLKDVFP-HGTGFVLVFDFMLSDLSEVIRNFQQ-PLTPAQVKGYMMMLLKGVAFLHHN  121

         *********.99***********************.************************

S: 120   kilHRDlKpqNlLiskegklklaDfGlarafssplkt.ytkevvTlwYraPelLlgakeY  178

         +i+HRDlKp+NlLis++g+lk+aDfGlar f +++++ y+++v T+wYraPelL+ga++Y

Q: 122   NIMHRDLKPANLLISSSGHLKIADFGLARLFTEQEDRlYSHQVATRWYRAPELLYGARKY  181

         *******************************8887755**********************

S: 179   stavDiWsvgcilaelltrkplfqgkseidqlerifkllgtpsekvwpevsklpeyk.ks  237

         ++ vD+W+vgci+ ell+ +plf+g+++i+ql  ++++lgtp+e++wpe+ +lp+y+  +

Q: 182   DEGVDLWAVGCIFGELLNLSPLFPGENDIEQLCCVLRVLGTPTEDSWPEIVELPDYNkIT  241

         *********************************************************778

S: 238   fpkkkkkklkekvkklkekaldllekllaldpkkRisakealqhkyf  284

         f+++++  l++ v++ + +a+dll ++l +   +R+sa++al h++f

Q: 242   FKENPAIPLEQIVPDSSPQAVDLLYNFLVYPSYRRCSARQALLHPFF  288

         8888888**************************************98

Domain Sequence
(FASTA)

YSILGRIGEG AHGIVFKAKH IETGETVALK KVALRRLEDG IPNQALREIK ALQEIEDNQH 60

VVKLKDVFPH GTGFVLVFDF MLSDLSEVIR NFQQPLTPAQ VKGYMMMLLK GVAFLHHNNI 120

MHRDLKPANL LISSSGHLKI ADFGLARLFT EQEDRLYSHQ VATRWYRAPE LLYGARKYDE 180

GVDLWAVGCI FGELLNLSPL FPGENDIEQL CCVLRVLGTP TEDSWPEIVE LPDYNKITFK 240

ENPAIPLEQI VPDSSPQAVD LLYNFLVYPS YRRCSARQAL LHPFF 285

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013